Development Level

Tbio 25 | 11,445
Tdark 6 | 6,588
Tchem 2 | 1,598

Collection

GPCR: IDG Consortium (Targets) 1 | 126

IMPC Phenotype

abnormal behavior 2 | 298
decreased body length 2 | 101
preweaning lethality, complete... 2 | 979
abnormal behavioral response t... 1 | 66
abnormal embryo size 1 | 220
abnormal seminal vesicle morph... 1 | 114
abnormal sleep behavior 1 | 70
abnormal tail movements 1 | 12
convulsive seizures 1 | 13
decreased circulating alanine ... 1 | 47
decreased circulating insulin ... 1 | 76
decreased grip strength 1 | 116
decreased threshold for audito... 1 | 26
embryonic growth retardation 1 | 106
embryonic lethality prior to t... 1 | 278
improved glucose tolerance 1 | 79
increased blood urea nitrogen ... 1 | 48
increased bone mineral density 1 | 72
increased circulating phosphat... 1 | 26
increased fasted circulating g... 1 | 76
increased vertical activity 1 | 24
male infertility 1 | 123
thrombocytopenia 1 | 56

Disease

Carcinoma 26 | 11,493
medulloblastoma, large-cell 16 | 6,241
ovarian cancer 16 | 8,520
lung cancer 14 | 4,740
atypical teratoid / rhabdoid tumor 12 | 5,112
ependymoma 12 | 4,679
lung adenocarcinoma 12 | 2,716
osteosarcoma 12 | 7,950
Breast cancer 11 | 3,578
glioblastoma 10 | 5,792
intraductal papillary-mucinous adenoma (IPMA) 10 | 2,955
intraductal papillary-mucinous carcinoma (IPMC) 10 | 2,989
non-small cell lung cancer 10 | 2,890
Kidney cancer 9 | 2,613
astrocytic glioma 9 | 2,597
intraductal papillary-mucinous neoplasm (IPMN) 9 | 3,291
invasive ductal carcinoma 9 | 2,951
lung carcinoma 9 | 2,843
malignant mesothelioma 9 | 3,232
oligodendroglioma 9 | 2,850
psoriasis 9 | 6,694
adult high grade glioma 8 | 3,801
colon cancer 8 | 1,478
group 3 medulloblastoma 8 | 4,104
Astrocytoma, Pilocytic 7 | 3,081
tuberculosis 7 | 2,010
Melanoma 6 | 711
Pick disease 6 | 1,894
Skin cancer 6 | 469
breast carcinoma 6 | 1,638
pancreatic cancer 6 | 2,398
subependymal giant cell astrocytoma 6 | 2,287
ulcerative colitis 6 | 1,819
Cancer 5 | 2,499
Rheumatoid arthritis 5 | 1,191
Substance-Related Disorders 5 | 115
ductal carcinoma in situ 5 | 1,745
primitive neuroectodermal tumor 5 | 3,035
Autosomal recessive predisposition 4 | 1,442
Schizophrenia 4 | 1,160
cystic fibrosis 4 | 1,696
dermatomyositis 4 | 966
interstitial cystitis 4 | 2,312
pancreatic ductal adenocarcinoma liver metastasis 4 | 1,962
Autistic Disorder 3 | 364
Cardiovascular system disease 3 | 246
Dental caries 3 | 164
Epilepsy 3 | 792
Liver cancer 3 | 604
Obesity 3 | 678
Osteoporosis 3 | 363
X-linked cerebral adrenoleukodystrophy 3 | 116
aldosterone-producing adenoma 3 | 665
astrocytoma 3 | 1,146
cutaneous lupus erythematosus 3 | 1,057
fibroadenoma 3 | 559
group 4 medulloblastoma 3 | 1,855
interstitial lung disease 3 | 298
non-small cell lung carcinoma 3 | 317
pediatric high grade glioma 3 | 1,064
pituitary cancer 3 | 1,972
Acquired metabolic disease 2 | 336
Alcoholic Intoxication, Chronic 2 | 289
Amyotrophic lateral sclerosis 2 | 451
Anorexia nervosa 2 | 80
Arrhythmogenic right ventricular cardiomyopathy 2 | 30
Asthma 2 | 385
Atopic dermatitis 2 | 952
Barrett's esophagus 2 | 182
Becker muscular dystrophy 2 | 191
Bipolar Disorder 2 | 666
Breast Neoplasms 2 | 445
Cardiomyopathy 2 | 116
Colorectal Neoplasms 2 | 243
Deafness 2 | 198
Endometrial cancer 2 | 311
Heart disease 2 | 306
Infantile onset 2 | 238
Large intestine cancer 2 | 126
Liver Cirrhosis, Experimental 2 | 769
Liver disease 2 | 237
Liver neoplasms 2 | 130
Mammary Neoplasms 2 | 425
Multiple Sclerosis 2 | 540
Multiple myeloma 2 | 1,332
Muscle Hypertonia 2 | 88
Polycystic ovary syndrome 2 | 360
Seizures 2 | 596
Stomach Neoplasms 2 | 300
Type 2 diabetes mellitus 2 | 272
adrenocortical carcinoma 2 | 1,428
atypical teratoid/rhabdoid tumor 2 | 357
autosomal dominant Emery-Dreifuss muscular dystrophy 2 | 510
chronic lymphosyte leukemia 2 | 204
diabetes mellitus 2 | 1,728
hepatocellular carcinoma 2 | 547
hereditary spastic paraplegia 2 | 318
primary Sjogren syndrome 2 | 735
primary pancreatic ductal adenocarcinoma 2 | 1,109
substance-related disorder 2 | 162

Tissue

Endocrine System 33 | 18,159
Nervous System 33 | 16,725
Blood and immune system 32 | 16,909
Digestive Tract 32 | 17,369
Female tissues 32 | 17,400
Male tissues 32 | 17,142
Skin and soft tissues 32 | 17,230
Liver and Pancreas 31 | 16,750
Respiratory system 31 | 16,393
Urinary Tract 31 | 16,678
Cardiovascular System 28 | 15,192

Target Family

Non-IDG 17 | 12,091
Enzyme 8 | 4,145
Transporter 4 | 473
GPCR 1 | 408
Kinase 1 | 634
Transcription Factor 1 | 1,400
oGPCR 1 | 421

GWAS Trait

Epstein-Barr virus copy number... 33 | 33
Obesity-related traits 569 | 569
Schizophrenia 533 | 533
Breast cancer 492 | 492
Body mass index 379 | 379
Height 369 | 369
Coronary artery disease 367 | 367
Blood protein levels 351 | 351
Post bronchodilator FEV1-FVC r... 308 | 308
Mean corpuscular volume 283 | 283
Platelet count 275 | 275
Intelligence (multi-trait anal... 267 | 267
Mean platelet volume 253 | 253
IgG glycosylation 250 | 250
Mean corpuscular hemoglobin 238 | 238
Inflammatory bowel disease 235 | 235
Plateletcrit 227 | 227
Crohn's disease 215 | 215
Type 2 diabetes 210 | 210
Red blood cell count 191 | 191
Monocyte count 183 | 183
Red cell distribution width 182 | 182
Eosinophil counts 180 | 180
Neuroticism 180 | 180
Platelet distribution width 174 | 174
Monocyte percentage of white c... 173 | 173
Post bronchodilator FEV1 173 | 173
Sum eosinophil basophil counts 173 | 173
White blood cell count 172 | 172
3-hydroxy-1-methylpropylmercap... 166 | 166
Eosinophil percentage of granu... 163 | 163
Eosinophil percentage of white... 163 | 163
Reticulocyte fraction of red c... 163 | 163
Ulcerative colitis 163 | 163
Granulocyte percentage of myel... 162 | 162
Itch intensity from mosquito b... 162 | 162
Systemic lupus erythematosus 159 | 159
High light scatter reticulocyt... 158 | 158
Lymphocyte counts 158 | 158
Reticulocyte count 158 | 158
Blood metabolite levels 157 | 157
Neutrophil count 154 | 154
High light scatter reticulocyt... 153 | 153
Neutrophil percentage of granu... 153 | 153
3-hydroxypropylmercapturic aci... 150 | 150
Tonsillectomy 149 | 149
Diastolic blood pressure 144 | 144
Sum basophil neutrophil counts 140 | 140
Autism spectrum disorder or sc... 134 | 134
Myeloid white cell count 133 | 133
Granulocyte count 132 | 132
Sum neutrophil eosinophil coun... 129 | 129
Colorectal cancer 126 | 126
Alzheimer disease and age of o... 124 | 124
Multiple sclerosis 124 | 124
Cholesterol, total 123 | 123
Night sleep phenotypes 123 | 123
Lung cancer 122 | 122
Lymphocyte percentage of white... 122 | 122
Menarche (age at onset) 122 | 122
Neutrophil percentage of white... 121 | 121
Rheumatoid arthritis 121 | 121
Systolic blood pressure 120 | 120
Immature fraction of reticuloc... 118 | 118
Diisocyanate-induced asthma 116 | 116
HDL cholesterol 116 | 116
Allergic disease (asthma, hay ... 115 | 115
Educational attainment (years ... 114 | 114
Hematocrit 113 | 113
Hemoglobin concentration 112 | 112
LDL cholesterol 110 | 110
QT interval 110 | 110
Waist circumference adjusted f... 110 | 110
Mosquito bite size 107 | 107
Asthma 106 | 106
Lobe attachment (rater-scored ... 103 | 103
Peripheral arterial disease (t... 101 | 101
Pulse pressure 97 | 97
Bipolar disorder 94 | 94
Major depressive disorder 94 | 94
Prostate cancer 92 | 92
Parkinson's disease 90 | 90
Hip circumference adjusted for... 89 | 89
Metabolite levels 87 | 87
Triglycerides 87 | 87
Colonoscopy-negative controls ... 85 | 85
Mean corpuscular hemoglobin co... 85 | 85
Itch intensity from mosquito b... 84 | 84
Bipolar disorder and schizophr... 83 | 83
Resting heart rate 82 | 82
Macrophage inflammatory protei... 81 | 81
Migraine 81 | 81
Waist-to-hip ratio adjusted fo... 81 | 81
PR interval in Tripanosoma cru... 80 | 80
Cognitive performance 79 | 79
Glomerular filtration rate (cr... 78 | 78
Late-onset Alzheimer's disease 78 | 78
Waist circumference adjusted f... 75 | 75
Tuberculosis 73 | 73
Type 1 diabetes 73 | 73
Morning vs. evening chronotype 72 | 72

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Protocadherin-15 PCDH15 Tbio Non-IDG -1.83877 74.3 42
Carboxypeptidase Q CPQ Tbio Enzyme -2.51783 330.9 81
Galactocerebrosidase GALC Tbio Enzyme -2.56924 363.2 143
Titin TTN Tbio Kinase -3.24415 1743.0 123
Mitochondrial carrier homolog 1 MTCH1 Tbio Non-IDG -0.76817 7.07 103
Protein Niban FAM129A Tbio Non-IDG -1.07686 12.9 159
Protein FAM184A FAM184A Tdark Non-IDG 1.00 0.08 22
O-acetyl-ADP-ribose deacetylase MACROD2 MACROD2 Tbio Enzyme -1.21785 14.5 19
FYVE, RhoGEF and PH domain-containing protein 2 FGD2 Tbio Non-IDG 0.00000 51
Scrapie-responsive protein 1 SCRG1 Tdark Non-IDG -0.66377 6.57 35