Development Level

Tbio 20 | 11,445
Tdark 4 | 6,588
Tchem 1 | 1,598

IMPC Phenotype

decreased lymphocyte cell numb... 3 | 83
decreased total body fat amoun... 3 | 207
abnormal seminal vesicle morph... 2 | 114
abnormal vertebrae morphology 2 | 18
decreased circulating choleste... 2 | 93
decreased leukocyte cell numbe... 2 | 73
decreased vertical activity 2 | 208
preweaning lethality, complete... 2 | 979
short tibia 2 | 97
abnormal bone structure 1 | 187
abnormal coat-hair pigmentatio... 1 | 64
abnormal cranium morphology 1 | 36
abnormal eye anterior chamber ... 1 | 9
abnormal heart morphology 1 | 162
abnormal joint morphology 1 | 23
abnormal kidney morphology 1 | 65
abnormal maxilla morphology 1 | 17
abnormal optic disc morphology 1 | 10
abnormal pelvic girdle bone mo... 1 | 12
abnormal retinal outer nuclear... 1 | 3
abnormal skin morphology 1 | 50
abnormal spleen morphology 1 | 55
abnormal testis morphology 1 | 43
abnormal vibrissa morphology 1 | 25
abnormal vitreous body morphol... 1 | 10
abnormal zygomatic bone morpho... 1 | 3
brachydactyly 1 | 19
decreased body length 1 | 101
decreased bone mineral density 1 | 126
decreased caudal vertebrae num... 1 | 53
decreased circulating HDL chol... 1 | 68
decreased circulating glucose ... 1 | 126
decreased circulating insulin ... 1 | 76
decreased circulating serum al... 1 | 82
decreased circulating total pr... 1 | 49
decreased startle reflex 1 | 75
decreased total retina thickne... 1 | 17
embryonic lethality prior to o... 1 | 239
embryonic lethality prior to t... 1 | 278
enlarged heart 1 | 210
enlarged spleen 1 | 41
female infertility 1 | 60
hydrometra 1 | 53
increased bone mineral content 1 | 108
increased bone mineral density 1 | 72
increased circulating alkaline... 1 | 122
increased lean body mass 1 | 172
increased leukocyte cell numbe... 1 | 47
increased lymphocyte cell numb... 1 | 32
polycystic kidney 1 | 15
preweaning lethality, incomple... 1 | 499
scaly skin 1 | 4
small superior vagus ganglion 1 | 74
small testis 1 | 58
syndactyly 1 | 23
vertebral fusion 1 | 23

Disease

Carcinoma 19 | 11,493
ovarian cancer 17 | 8,520
lung cancer 12 | 4,740
medulloblastoma, large-cell 12 | 6,241
osteosarcoma 12 | 7,950
Breast cancer 11 | 3,578
lung carcinoma 9 | 2,843
atypical teratoid / rhabdoid tumor 8 | 5,112
psoriasis 8 | 6,694
glioblastoma 7 | 5,792
invasive ductal carcinoma 7 | 2,951
Astrocytoma, Pilocytic 6 | 3,081
Cancer 6 | 2,499
Ovarian Neoplasms 6 | 102
adult high grade glioma 6 | 3,801
ependymoma 6 | 4,679
intraductal papillary-mucinous carcinoma (IPMC) 6 | 2,989
intraductal papillary-mucinous neoplasm (IPMN) 6 | 3,291
lung adenocarcinoma 6 | 2,716
ovarian neoplasm 6 | 99
Epithelial ovarian cancer 5 | 9
Kidney cancer 5 | 2,613
Ovarian epithelial cancer 5 | 10
Prostatic Neoplasms 5 | 495
group 3 medulloblastoma 5 | 4,104
interstitial cystitis 5 | 2,312
intraductal papillary-mucinous adenoma (IPMA) 5 | 2,955
pancreatic cancer 5 | 2,398
primitive neuroectodermal tumor 5 | 3,035
Pick disease 4 | 1,894
Prostate cancer 4 | 175
acute quadriplegic myopathy 4 | 1,158
astrocytic glioma 4 | 2,597
breast carcinoma 4 | 1,638
cystic fibrosis 4 | 1,696
oligodendroglioma 4 | 2,850
spina bifida 4 | 1,074
Amyotrophic lateral sclerosis 3 | 451
Autosomal recessive predisposition 3 | 1,442
Carcinoma, Renal Cell 3 | 124
Melanoma 3 | 711
Renal Cell Carcinoma 3 | 214
Short stature 3 | 531
Type 2 diabetes mellitus 3 | 272
adrenocortical carcinoma 3 | 1,428
aldosterone-producing adenoma 3 | 665
diabetes mellitus 3 | 1,728
ductal carcinoma in situ 3 | 1,745
group 4 medulloblastoma 3 | 1,855
malignant mesothelioma 3 | 3,232
non primary Sjogren syndrome sicca 3 | 891
non-small cell lung cancer 3 | 2,890
subependymal giant cell astrocytoma 3 | 2,287
tuberculosis 3 | 2,010
Adenoma 2 | 167
Alcoholic Intoxication, Chronic 2 | 289
Anemia 2 | 365
Atopic dermatitis 2 | 952
Cerebral atrophy 2 | 178
Coronary artery disease 2 | 268
Diabetes Mellitus, Non-Insulin-Dependent 2 | 145
Diabetes Mellitus, Type 2 2 | 142
Dystrophia unguium 2 | 53
Elevated hepatic transaminases 2 | 81
Endometriosis 2 | 540
Failure to gain weight 2 | 365
Gout 2 | 106
Hemoglobin low 2 | 124
Hepatic enzyme increased 2 | 81
Highly variable clinical phenotype 2 | 150
Highly variable phenotype and severity 2 | 150
Highly variable phenotype, even within families 2 | 150
Infantile onset 2 | 238
Kidney disease 2 | 430
Liver Dysfunction 2 | 99
Liver enzymes abnormal 2 | 81
Liver function test increased 2 | 81
Liver function tests abnormal finding 2 | 81
Osteoporosis 2 | 363
Pancreatic Neoplasm 2 | 85
Pancreatic Neoplasms 2 | 85
Parkinson's disease 2 | 392
Pediatric failure to thrive 2 | 365
Penile hypospadias 2 | 106
Phenotypic variability 2 | 150
Refractive error 2 | 50
Schizophrenia 2 | 1,160
Skin cancer 2 | 469
Subclinical abnormal liver function tests 2 | 81
Transaminases increased 2 | 81
active ulcerative colitis 2 | 764
acute myeloid leukemia 2 | 783
colon cancer 2 | 1,478
esophageal adenocarcinoma 2 | 737
fibroadenoma 2 | 559
nasopharyngeal carcinoma 2 | 1,058
pancreatic ductal adenocarcinoma liver metastasis 2 | 1,962
pituitary cancer 2 | 1,972
primary pancreatic ductal adenocarcinoma 2 | 1,109
urothelial carcinoma 2 | 318

Tissue

Endocrine System 22 | 18,159
Male tissues 22 | 17,142
Digestive Tract 21 | 17,369
Female tissues 20 | 17,400
Liver and Pancreas 20 | 16,750
Skin and soft tissues 20 | 17,230
Urinary Tract 20 | 16,678
Blood and immune system 19 | 16,909
Respiratory system 19 | 16,393
Nervous System 18 | 16,725
Cardiovascular System 15 | 15,192

Target Family

Enzyme 10 | 4,145
Non-IDG 10 | 12,091
Transcription Factor 4 | 1,400
Epigenetic 1 | 242

GWAS Trait

Epithelial ovarian cancer 25 | 25
Obesity-related traits 569 | 569
Schizophrenia 533 | 533
Breast cancer 492 | 492
Body mass index 379 | 379
Height 369 | 369
Coronary artery disease 367 | 367
Blood protein levels 351 | 351
Post bronchodilator FEV1-FVC r... 308 | 308
Mean corpuscular volume 283 | 283
Platelet count 275 | 275
Intelligence (multi-trait anal... 267 | 267
Mean platelet volume 253 | 253
IgG glycosylation 250 | 250
Mean corpuscular hemoglobin 238 | 238
Inflammatory bowel disease 235 | 235
Plateletcrit 227 | 227
Crohn's disease 215 | 215
Type 2 diabetes 210 | 210
Red blood cell count 191 | 191
Monocyte count 183 | 183
Red cell distribution width 182 | 182
Eosinophil counts 180 | 180
Neuroticism 180 | 180
Platelet distribution width 174 | 174
Monocyte percentage of white c... 173 | 173
Post bronchodilator FEV1 173 | 173
Sum eosinophil basophil counts 173 | 173
White blood cell count 172 | 172
3-hydroxy-1-methylpropylmercap... 166 | 166
Eosinophil percentage of granu... 163 | 163
Eosinophil percentage of white... 163 | 163
Reticulocyte fraction of red c... 163 | 163
Ulcerative colitis 163 | 163
Granulocyte percentage of myel... 162 | 162
Itch intensity from mosquito b... 162 | 162
Systemic lupus erythematosus 159 | 159
High light scatter reticulocyt... 158 | 158
Lymphocyte counts 158 | 158
Reticulocyte count 158 | 158
Blood metabolite levels 157 | 157
Neutrophil count 154 | 154
High light scatter reticulocyt... 153 | 153
Neutrophil percentage of granu... 153 | 153
3-hydroxypropylmercapturic aci... 150 | 150
Tonsillectomy 149 | 149
Diastolic blood pressure 144 | 144
Sum basophil neutrophil counts 140 | 140
Autism spectrum disorder or sc... 134 | 134
Myeloid white cell count 133 | 133
Granulocyte count 132 | 132
Sum neutrophil eosinophil coun... 129 | 129
Colorectal cancer 126 | 126
Alzheimer disease and age of o... 124 | 124
Multiple sclerosis 124 | 124
Cholesterol, total 123 | 123
Night sleep phenotypes 123 | 123
Lung cancer 122 | 122
Lymphocyte percentage of white... 122 | 122
Menarche (age at onset) 122 | 122
Neutrophil percentage of white... 121 | 121
Rheumatoid arthritis 121 | 121
Systolic blood pressure 120 | 120
Immature fraction of reticuloc... 118 | 118
Diisocyanate-induced asthma 116 | 116
HDL cholesterol 116 | 116
Allergic disease (asthma, hay ... 115 | 115
Educational attainment (years ... 114 | 114
Hematocrit 113 | 113
Hemoglobin concentration 112 | 112
LDL cholesterol 110 | 110
QT interval 110 | 110
Waist circumference adjusted f... 110 | 110
Mosquito bite size 107 | 107
Asthma 106 | 106
Lobe attachment (rater-scored ... 103 | 103
Peripheral arterial disease (t... 101 | 101
Pulse pressure 97 | 97
Bipolar disorder 94 | 94
Major depressive disorder 94 | 94
Prostate cancer 92 | 92
Parkinson's disease 90 | 90
Hip circumference adjusted for... 89 | 89
Metabolite levels 87 | 87
Triglycerides 87 | 87
Colonoscopy-negative controls ... 85 | 85
Mean corpuscular hemoglobin co... 85 | 85
Itch intensity from mosquito b... 84 | 84
Bipolar disorder and schizophr... 83 | 83
Resting heart rate 82 | 82
Macrophage inflammatory protei... 81 | 81
Migraine 81 | 81
Waist-to-hip ratio adjusted fo... 81 | 81
PR interval in Tripanosoma cru... 80 | 80
Cognitive performance 79 | 79
Glomerular filtration rate (cr... 78 | 78
Late-onset Alzheimer's disease 78 | 78
Waist circumference adjusted f... 75 | 75
Tuberculosis 73 | 73
Type 1 diabetes 73 | 73
Morning vs. evening chronotype 72 | 72

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Pleckstrin homology domain-containing family M member 1 PLEKHM1 Tbio Non-IDG -1.44998 27.9 116
Acyl-coenzyme A oxidase-like protein ACOXL Tdark Enzyme -0.18122 1.46 28
Collagen alpha-1(XV) chain COL15A1 Tbio Non-IDG -1.18716 15.5 74
Histo-blood group ABO system transferase ABO Tbio Enzyme 0.00000 0
Ankyrin repeat and LEM domain-containing protein 1 ANKLE1 Tbio Non-IDG -1.22574 16.7 31
Zinc finger protein basonuclin-2 BNC2 Tbio Transcription Factor -1.47650 30.8 61
Synaptopodin-2 SYNPO2 Tbio Non-IDG -1.31714 27.9 42
SLIT-ROBO Rho GTPase-activating protein 1 SRGAP1 Tbio Enzyme -0.99760 9.60 170
Homeobox protein Hox-D3 HOXD3 Tbio Transcription Factor -1.51371 40.2 144
Charged multivesicular body protein 4c CHMP4C Tbio Non-IDG -0.86389 7.74 42