Development Level

Tbio 110 | 11,445
Tchem 22 | 1,598
Tdark 17 | 6,588
Tclin 14 | 613

IMPC Phenotype

preweaning lethality, complete... 10 | 979
embryonic lethality prior to t... 6 | 278
embryonic lethality prior to o... 4 | 239
abnormal embryo size 3 | 220
abnormal heart morphology 3 | 162
increased grip strength 3 | 41
increased neutrophil cell numb... 3 | 46
preweaning lethality, incomple... 3 | 499
abnormal coat-hair pigmentatio... 2 | 64
abnormal cornea morphology 2 | 31
corneal opacity 2 | 32
decreased body weight 2 | 161
decreased circulating amylase ... 2 | 28
decreased fasted circulating g... 2 | 65
decreased large unstained cell... 2 | 11
decreased lymphocyte cell numb... 2 | 83
embryonic growth retardation 2 | 106
enlarged heart 2 | 210
hydrometra 2 | 53
increased anti-nuclear antigen... 2 | 19
increased circulating alkaline... 2 | 122
increased lean body mass 2 | 172
increased leukocyte cell numbe... 2 | 47
increased monocyte cell number 2 | 63
increased startle reflex 2 | 112
prenatal lethality prior to he... 2 | 87
short tibia 2 | 97
thrombocytopenia 2 | 56
abnormal behavior 1 | 298
abnormal bone structure 1 | 187
abnormal eye anterior chamber ... 1 | 9
abnormal eye morphology 1 | 68
abnormal gait 1 | 69
abnormal kidney morphology 1 | 65
abnormal lens morphology 1 | 81
abnormal liver morphology 1 | 17
abnormal locomotor activation 1 | 16
abnormal maxilla morphology 1 | 17
abnormal pericardium morpholog... 1 | 26
abnormal retinal outer nuclear... 1 | 3
abnormal seminal vesicle morph... 1 | 114
abnormal skin condition 1 | 6
abnormal skin morphology 1 | 50
abnormal tooth morphology 1 | 24
abnormal vitelline vasculature... 1 | 6
anophthalmia 1 | 33
cardiovascular system phenotyp... 1 | 36
cataract 1 | 92
decreased basophil cell number 1 | 16
decreased body length 1 | 101
decreased bone mineral content 1 | 151
decreased bone mineral density 1 | 126
decreased circulating HDL chol... 1 | 68
decreased circulating alanine ... 1 | 47
decreased circulating aspartat... 1 | 34
decreased circulating bilirubi... 1 | 19
decreased circulating calcium ... 1 | 36
decreased circulating choleste... 1 | 93
decreased circulating creatini... 1 | 39
decreased circulating fructosa... 1 | 30
decreased circulating glucose ... 1 | 126
decreased circulating insulin ... 1 | 76
decreased circulating serum al... 1 | 82
decreased circulating sodium l... 1 | 22
decreased circulating total pr... 1 | 49
decreased circulating triglyce... 1 | 79
decreased grip strength 1 | 116
decreased lean body mass 1 | 135
decreased leukocyte cell numbe... 1 | 73
decreased mean corpuscular hem... 1 | 31
decreased neutrophil cell numb... 1 | 42
decreased prepulse inhibition 1 | 82
decreased startle reflex 1 | 75
decreased thermal nociceptive ... 1 | 2
decreased total body fat amoun... 1 | 207
decreased total retina thickne... 1 | 17
enlarged testis 1 | 6
head bobbing 1 | 5
hemorrhage 1 | 23
hyperactivity 1 | 148
impaired pupillary reflex 1 | 26
increased circulating HDL chol... 1 | 80
increased circulating amylase ... 1 | 25
increased circulating choleste... 1 | 66
increased circulating free fat... 1 | 20
increased fasted circulating g... 1 | 76
increased heart rate variabili... 1 | 7
increased lymphocyte cell numb... 1 | 32
increased mean corpuscular hem... 1 | 96
increased spleen weight 1 | 10
increased thermal nociceptive ... 1 | 9
increased total body fat amoun... 1 | 134
irregularly shaped pupil 1 | 7
long tibia 1 | 25
male infertility 1 | 123
mydriasis 1 | 6
pale yolk sac 1 | 25
prenatal lethality 1 | 28
small superior vagus ganglion 1 | 74
unresponsive to tactile stimul... 1 | 8

Disease

Carcinoma 114 | 11,493
osteosarcoma 96 | 7,950
ovarian cancer 88 | 8,520
medulloblastoma, large-cell 68 | 6,241
psoriasis 68 | 6,694
lung cancer 56 | 4,740
glioblastoma 55 | 5,792
Cancer 45 | 2,499
atypical teratoid / rhabdoid tumor 41 | 5,112
adult high grade glioma 39 | 3,801
ependymoma 39 | 4,679
tuberculosis 39 | 2,010
group 3 medulloblastoma 34 | 4,104
Breast cancer 33 | 3,578
intraductal papillary-mucinous neoplasm (IPMN) 33 | 3,291
ulcerative colitis 32 | 1,819
Astrocytoma, Pilocytic 31 | 3,081
lung carcinoma 31 | 2,843
malignant mesothelioma 31 | 3,232
non-small cell lung cancer 31 | 2,890
Kidney cancer 30 | 2,613
interstitial cystitis 30 | 2,312
invasive ductal carcinoma 28 | 2,951
lung adenocarcinoma 28 | 2,716
Asthma 27 | 385
primitive neuroectodermal tumor 27 | 3,035
intraductal papillary-mucinous adenoma (IPMA) 26 | 2,955
intraductal papillary-mucinous carcinoma (IPMC) 26 | 2,989
pancreatic cancer 25 | 2,398
subependymal giant cell astrocytoma 25 | 2,287
diabetes mellitus 24 | 1,728
Crohn's disease 22 | 321
Pick disease 22 | 1,894
oligodendroglioma 21 | 2,850
pancreatic ductal adenocarcinoma liver metastasis 21 | 1,962
Rheumatoid arthritis 20 | 1,191
group 4 medulloblastoma 20 | 1,855
Atopic dermatitis 19 | 952
Autosomal recessive predisposition 19 | 1,442
Schizophrenia 19 | 1,160
astrocytic glioma 19 | 2,597
pituitary cancer 19 | 1,972
Multiple myeloma 18 | 1,332
astrocytoma 18 | 1,146
cystic fibrosis 17 | 1,696
ductal carcinoma in situ 15 | 1,745
Multiple Sclerosis 14 | 540
acute quadriplegic myopathy 14 | 1,158
primary Sjogren syndrome 14 | 735
Alzheimer's disease 13 | 658
Breast Neoplasms 13 | 445
Liver Cirrhosis, Experimental 13 | 769
Liver cancer 13 | 604
Mammary Neoplasms 13 | 425
breast carcinoma 13 | 1,638
colon cancer 13 | 1,478
primary pancreatic ductal adenocarcinoma 13 | 1,109
Celiac disease 12 | 116
Inflammatory bowel disease 12 | 151
Intellectual disability 12 | 1,016
Obesity 12 | 678
juvenile dermatomyositis 12 | 1,187
spina bifida 12 | 1,074
Chronic Lymphocytic Leukemia 11 | 262
Kidney disease 11 | 430
Waldenstrons macroglobulinemia 11 | 765
cutaneous lupus erythematosus 11 | 1,057
non primary Sjogren syndrome sicca 11 | 891
Allergic rhinitis 10 | 94
Bipolar Disorder 10 | 666
Hypereosinophilic syndrome 10 | 71
Hypersensitivity reaction type II disease 10 | 253
Leukemia, Myelocytic, Acute 10 | 120
Lymphoid leukemia 10 | 160
Muscle hypotonia 10 | 571
Prostatic Neoplasms 10 | 495
nasopharyngeal carcinoma 10 | 1,058
progressive supranuclear palsy 10 | 676
Atherosclerosis 9 | 291
Autistic Disorder 9 | 364
Hypertension 9 | 396
Leukemia, Myeloid, Acute 9 | 105
Polycystic ovary syndrome 9 | 360
Vascular disease 9 | 319
active Crohn's disease 9 | 922
active ulcerative colitis 9 | 764
acute myeloid leukemia 9 | 783
adrenocortical carcinoma 9 | 1,428
dermatomyositis 9 | 966
fibroadenoma 9 | 559
gastric carcinoma 9 | 807
Cognitive delay 8 | 608
Dull intelligence 8 | 645
Global developmental delay 8 | 608
Low intelligence 8 | 645
Mental Retardation 8 | 645
Mental and motor retardation 8 | 608
Mental deficiency 8 | 645
Poor school performance 8 | 645
Splenomegaly 8 | 190

Tissue

Endocrine System 154 | 18,159
Digestive Tract 153 | 17,369
Female tissues 152 | 17,400
Blood and immune system 151 | 16,909
Skin and soft tissues 151 | 17,230
Male tissues 150 | 17,142
Urinary Tract 150 | 16,678
Liver and Pancreas 149 | 16,750
Nervous System 148 | 16,725
Respiratory system 146 | 16,393
Cardiovascular System 138 | 15,192

Target Family

Non-IDG 78 | 12,091
Enzyme 31 | 4,145
Transcription Factor 28 | 1,400
Kinase 10 | 634
GPCR 7 | 408
Epigenetic 4 | 242
Transporter 2 | 473
Ion Channel 1 | 344
Nuclear Receptor 1 | 48
TF/Epigenetic 1 | 38

GWAS Trait

Eosinophil percentage of white... 163 | 163
Obesity-related traits 569 | 569
Schizophrenia 533 | 533
Breast cancer 492 | 492
Body mass index 379 | 379
Height 369 | 369
Coronary artery disease 367 | 367
Blood protein levels 351 | 351
Post bronchodilator FEV1-FVC r... 308 | 308
Mean corpuscular volume 283 | 283
Platelet count 275 | 275
Intelligence (multi-trait anal... 267 | 267
Mean platelet volume 253 | 253
IgG glycosylation 250 | 250
Mean corpuscular hemoglobin 238 | 238
Inflammatory bowel disease 235 | 235
Plateletcrit 227 | 227
Crohn's disease 215 | 215
Type 2 diabetes 210 | 210
Red blood cell count 191 | 191
Monocyte count 183 | 183
Red cell distribution width 182 | 182
Eosinophil counts 180 | 180
Neuroticism 180 | 180
Platelet distribution width 174 | 174
Monocyte percentage of white c... 173 | 173
Post bronchodilator FEV1 173 | 173
Sum eosinophil basophil counts 173 | 173
White blood cell count 172 | 172
3-hydroxy-1-methylpropylmercap... 166 | 166
Eosinophil percentage of granu... 163 | 163
Reticulocyte fraction of red c... 163 | 163
Ulcerative colitis 163 | 163
Granulocyte percentage of myel... 162 | 162
Itch intensity from mosquito b... 162 | 162
Systemic lupus erythematosus 159 | 159
High light scatter reticulocyt... 158 | 158
Lymphocyte counts 158 | 158
Reticulocyte count 158 | 158
Blood metabolite levels 157 | 157
Neutrophil count 154 | 154
High light scatter reticulocyt... 153 | 153
Neutrophil percentage of granu... 153 | 153
3-hydroxypropylmercapturic aci... 150 | 150
Tonsillectomy 149 | 149
Diastolic blood pressure 144 | 144
Sum basophil neutrophil counts 140 | 140
Autism spectrum disorder or sc... 134 | 134
Myeloid white cell count 133 | 133
Granulocyte count 132 | 132
Sum neutrophil eosinophil coun... 129 | 129
Colorectal cancer 126 | 126
Alzheimer disease and age of o... 124 | 124
Multiple sclerosis 124 | 124
Cholesterol, total 123 | 123
Night sleep phenotypes 123 | 123
Lung cancer 122 | 122
Lymphocyte percentage of white... 122 | 122
Menarche (age at onset) 122 | 122
Neutrophil percentage of white... 121 | 121
Rheumatoid arthritis 121 | 121
Systolic blood pressure 120 | 120
Immature fraction of reticuloc... 118 | 118
Diisocyanate-induced asthma 116 | 116
HDL cholesterol 116 | 116
Allergic disease (asthma, hay ... 115 | 115
Educational attainment (years ... 114 | 114
Hematocrit 113 | 113
Hemoglobin concentration 112 | 112
LDL cholesterol 110 | 110
QT interval 110 | 110
Waist circumference adjusted f... 110 | 110
Mosquito bite size 107 | 107
Asthma 106 | 106
Lobe attachment (rater-scored ... 103 | 103
Peripheral arterial disease (t... 101 | 101
Pulse pressure 97 | 97
Bipolar disorder 94 | 94
Major depressive disorder 94 | 94
Prostate cancer 92 | 92
Parkinson's disease 90 | 90
Hip circumference adjusted for... 89 | 89
Metabolite levels 87 | 87
Triglycerides 87 | 87
Colonoscopy-negative controls ... 85 | 85
Mean corpuscular hemoglobin co... 85 | 85
Itch intensity from mosquito b... 84 | 84
Bipolar disorder and schizophr... 83 | 83
Resting heart rate 82 | 82
Macrophage inflammatory protei... 81 | 81
Migraine 81 | 81
Waist-to-hip ratio adjusted fo... 81 | 81
PR interval in Tripanosoma cru... 80 | 80
Cognitive performance 79 | 79
Glomerular filtration rate (cr... 78 | 78
Late-onset Alzheimer's disease 78 | 78
Waist circumference adjusted f... 75 | 75
Tuberculosis 73 | 73
Type 1 diabetes 73 | 73
Morning vs. evening chronotype 72 | 72

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Zinc finger protein Helios IKZF2 Tbio Transcription Factor -1.26324 15.8 221
Krueppel-like factor 2 KLF2 Tbio Transcription Factor -2.30630 216.2 308
Adenylate kinase isoenzyme 5 AK5 Tbio Kinase -1.83209 76.0 225
Transcriptional-regulating factor 1 TRERF1 Tbio Transcription Factor -0.69436 6.18 146
5-hydroxytryptamine receptor 4 HTR4 Tclin GPCR -2.87235 796.4 248
Serpin B12 SERPINB12 Tbio Non-IDG -0.56624 4.27 155
Serine/threonine-protein kinase SIK3 SIK3 Tchem Kinase -1.18286 18.2 0
Mitochondrial peptide methionine sulfoxide reductase MSRA Tbio Enzyme -1.92325 88.1 167
Suppressor of tumorigenicity 20 protein ST20 Tdark Non-IDG -1.66163 0.71 0
Lysine-specific demethylase 6B KDM6B Tchem Epigenetic -2.22888 174.2 272