Development Level

Tbio 115 | 11,445
Tdark 19 | 6,588
Tchem 17 | 1,598
Tclin 12 | 613

IMPC Phenotype

preweaning lethality, complete... 11 | 979
embryonic lethality prior to t... 5 | 278
abnormal embryo size 3 | 220
embryonic lethality prior to o... 3 | 239
increased grip strength 3 | 41
abnormal coat-hair pigmentatio... 2 | 64
abnormal cornea morphology 2 | 31
abnormal heart morphology 2 | 162
corneal opacity 2 | 32
decreased circulating amylase ... 2 | 28
decreased fasted circulating g... 2 | 65
decreased large unstained cell... 2 | 11
decreased lymphocyte cell numb... 2 | 83
embryonic growth retardation 2 | 106
hydrometra 2 | 53
hyperactivity 2 | 148
increased circulating alkaline... 2 | 122
increased lean body mass 2 | 172
increased leukocyte cell numbe... 2 | 47
increased monocyte cell number 2 | 63
increased neutrophil cell numb... 2 | 46
prenatal lethality prior to he... 2 | 87
preweaning lethality, incomple... 2 | 499
abnormal behavior 1 | 298
abnormal bone structure 1 | 187
abnormal eye anterior chamber ... 1 | 9
abnormal eye morphology 1 | 68
abnormal gait 1 | 69
abnormal kidney morphology 1 | 65
abnormal lens morphology 1 | 81
abnormal liver morphology 1 | 17
abnormal locomotor activation 1 | 16
abnormal maxilla morphology 1 | 17
abnormal pericardium morpholog... 1 | 26
abnormal retinal outer nuclear... 1 | 3
abnormal seminal vesicle morph... 1 | 114
abnormal skin condition 1 | 6
abnormal tooth morphology 1 | 24
abnormal vitelline vasculature... 1 | 6
anophthalmia 1 | 33
cataract 1 | 92
decreased basophil cell number 1 | 16
decreased body length 1 | 101
decreased body weight 1 | 161
decreased bone mineral content 1 | 151
decreased bone mineral density 1 | 126
decreased circulating HDL chol... 1 | 68
decreased circulating alanine ... 1 | 47
decreased circulating aspartat... 1 | 34
decreased circulating bilirubi... 1 | 19
decreased circulating calcium ... 1 | 36
decreased circulating choleste... 1 | 93
decreased circulating creatini... 1 | 39
decreased circulating fructosa... 1 | 30
decreased circulating insulin ... 1 | 76
decreased circulating serum al... 1 | 82
decreased circulating sodium l... 1 | 22
decreased circulating total pr... 1 | 49
decreased circulating triglyce... 1 | 79
decreased grip strength 1 | 116
decreased lean body mass 1 | 135
decreased leukocyte cell numbe... 1 | 73
decreased lumbar vertebrae num... 1 | 2
decreased mean corpuscular hem... 1 | 31
decreased neutrophil cell numb... 1 | 42
decreased prepulse inhibition 1 | 82
decreased startle reflex 1 | 75
decreased thermal nociceptive ... 1 | 2
decreased total body fat amoun... 1 | 207
decreased total retina thickne... 1 | 17
enlarged heart 1 | 210
head bobbing 1 | 5
hemorrhage 1 | 23
impaired pupillary reflex 1 | 26
increased anti-nuclear antigen... 1 | 19
increased circulating HDL chol... 1 | 80
increased circulating amylase ... 1 | 25
increased circulating choleste... 1 | 66
increased circulating free fat... 1 | 20
increased lymphocyte cell numb... 1 | 32
increased mean corpuscular hem... 1 | 96
increased startle reflex 1 | 112
increased thermal nociceptive ... 1 | 9
increased total body fat amoun... 1 | 134
irregularly shaped pupil 1 | 7
long tibia 1 | 25
male infertility 1 | 123
mydriasis 1 | 6
pale yolk sac 1 | 25
prenatal lethality 1 | 28
short tibia 1 | 97
small superior vagus ganglion 1 | 74
thrombocytopenia 1 | 56
unresponsive to tactile stimul... 1 | 8

Disease

Carcinoma 103 | 11,493
osteosarcoma 96 | 7,950
ovarian cancer 88 | 8,520
medulloblastoma, large-cell 65 | 6,241
psoriasis 65 | 6,694
glioblastoma 58 | 5,792
lung cancer 58 | 4,740
Cancer 43 | 2,499
tuberculosis 43 | 2,010
atypical teratoid / rhabdoid tumor 41 | 5,112
adult high grade glioma 37 | 3,801
non-small cell lung cancer 37 | 2,890
ependymoma 36 | 4,679
lung carcinoma 35 | 2,843
group 3 medulloblastoma 34 | 4,104
invasive ductal carcinoma 33 | 2,951
intraductal papillary-mucinous neoplasm (IPMN) 32 | 3,291
malignant mesothelioma 32 | 3,232
ulcerative colitis 32 | 1,819
Astrocytoma, Pilocytic 30 | 3,081
Breast cancer 30 | 3,578
interstitial cystitis 29 | 2,312
intraductal papillary-mucinous adenoma (IPMA) 29 | 2,955
intraductal papillary-mucinous carcinoma (IPMC) 29 | 2,989
lung adenocarcinoma 28 | 2,716
Kidney cancer 27 | 2,613
Asthma 26 | 385
primitive neuroectodermal tumor 26 | 3,035
diabetes mellitus 25 | 1,728
Crohn's disease 24 | 321
Rheumatoid arthritis 23 | 1,191
Pick disease 22 | 1,894
subependymal giant cell astrocytoma 22 | 2,287
oligodendroglioma 21 | 2,850
pancreatic cancer 21 | 2,398
group 4 medulloblastoma 20 | 1,855
pancreatic ductal adenocarcinoma liver metastasis 20 | 1,962
pituitary cancer 20 | 1,972
cystic fibrosis 19 | 1,696
Atopic dermatitis 18 | 952
Multiple myeloma 18 | 1,332
astrocytic glioma 17 | 2,597
Autosomal recessive predisposition 16 | 1,442
astrocytoma 16 | 1,146
ductal carcinoma in situ 16 | 1,745
primary Sjogren syndrome 16 | 735
Breast Neoplasms 15 | 445
Mammary Neoplasms 15 | 425
Schizophrenia 15 | 1,160
breast carcinoma 15 | 1,638
colon cancer 15 | 1,478
Multiple Sclerosis 14 | 540
cutaneous lupus erythematosus 14 | 1,057
juvenile dermatomyositis 14 | 1,187
spina bifida 14 | 1,074
Intellectual disability 13 | 1,016
Liver Cirrhosis, Experimental 13 | 769
Liver cancer 13 | 604
acute quadriplegic myopathy 13 | 1,158
active ulcerative colitis 12 | 764
non primary Sjogren syndrome sicca 12 | 891
primary pancreatic ductal adenocarcinoma 12 | 1,109
Alzheimer's disease 11 | 658
Bipolar Disorder 11 | 666
Celiac disease 11 | 116
Inflammatory bowel disease 11 | 151
Leukemia, Myelocytic, Acute 11 | 120
Prostatic Neoplasms 11 | 495
Waldenstrons macroglobulinemia 11 | 765
acute myeloid leukemia 11 | 783
dermatomyositis 11 | 966
Arthritis, Rheumatoid 10 | 174
Chronic Lymphocytic Leukemia 10 | 262
Hypereosinophilic syndrome 10 | 71
Hypersensitivity reaction type II disease 10 | 253
Kidney disease 10 | 430
Leukemia, Myeloid, Acute 10 | 105
Obesity 10 | 678
Vascular disease 10 | 319
adrenocortical carcinoma 10 | 1,428
Allergic rhinitis 9 | 94
Atherosclerosis 9 | 291
Dull intelligence 9 | 645
Low intelligence 9 | 645
Lymphoid leukemia 9 | 160
Mental Retardation 9 | 645
Mental deficiency 9 | 645
Muscle hypotonia 9 | 571
Poor school performance 9 | 645
active Crohn's disease 9 | 922
fibroadenoma 9 | 559
nasopharyngeal carcinoma 9 | 1,058
progressive supranuclear palsy 9 | 676
Cognitive delay 8 | 608
Depressive disorder 8 | 409
Global developmental delay 8 | 608
Mental and motor retardation 8 | 608
Myocardial Ischemia 8 | 169
gastric carcinoma 8 | 807
hepatocellular carcinoma 8 | 547

Tissue

Endocrine System 154 | 18,159
Digestive Tract 153 | 17,369
Female tissues 153 | 17,400
Blood and immune system 152 | 16,909
Skin and soft tissues 152 | 17,230
Urinary Tract 151 | 16,678
Liver and Pancreas 149 | 16,750
Male tissues 149 | 17,142
Nervous System 149 | 16,725
Respiratory system 147 | 16,393
Cardiovascular System 138 | 15,192

Target Family

Non-IDG 81 | 12,091
Enzyme 31 | 4,145
Transcription Factor 31 | 1,400
GPCR 7 | 408
Epigenetic 5 | 242
Kinase 5 | 634
Nuclear Receptor 1 | 48
TF/Epigenetic 1 | 38
Transporter 1 | 473

GWAS Trait

Eosinophil percentage of granu... 163 | 163
Obesity-related traits 569 | 569
Schizophrenia 533 | 533
Breast cancer 492 | 492
Body mass index 379 | 379
Height 369 | 369
Coronary artery disease 367 | 367
Blood protein levels 351 | 351
Post bronchodilator FEV1-FVC r... 308 | 308
Mean corpuscular volume 283 | 283
Platelet count 275 | 275
Intelligence (multi-trait anal... 267 | 267
Mean platelet volume 253 | 253
IgG glycosylation 250 | 250
Mean corpuscular hemoglobin 238 | 238
Inflammatory bowel disease 235 | 235
Plateletcrit 227 | 227
Crohn's disease 215 | 215
Type 2 diabetes 210 | 210
Red blood cell count 191 | 191
Monocyte count 183 | 183
Red cell distribution width 182 | 182
Eosinophil counts 180 | 180
Neuroticism 180 | 180
Platelet distribution width 174 | 174
Monocyte percentage of white c... 173 | 173
Post bronchodilator FEV1 173 | 173
Sum eosinophil basophil counts 173 | 173
White blood cell count 172 | 172
3-hydroxy-1-methylpropylmercap... 166 | 166
Eosinophil percentage of white... 163 | 163
Reticulocyte fraction of red c... 163 | 163
Ulcerative colitis 163 | 163
Granulocyte percentage of myel... 162 | 162
Itch intensity from mosquito b... 162 | 162
Systemic lupus erythematosus 159 | 159
High light scatter reticulocyt... 158 | 158
Lymphocyte counts 158 | 158
Reticulocyte count 158 | 158
Blood metabolite levels 157 | 157
Neutrophil count 154 | 154
High light scatter reticulocyt... 153 | 153
Neutrophil percentage of granu... 153 | 153
3-hydroxypropylmercapturic aci... 150 | 150
Tonsillectomy 149 | 149
Diastolic blood pressure 144 | 144
Sum basophil neutrophil counts 140 | 140
Autism spectrum disorder or sc... 134 | 134
Myeloid white cell count 133 | 133
Granulocyte count 132 | 132
Sum neutrophil eosinophil coun... 129 | 129
Colorectal cancer 126 | 126
Alzheimer disease and age of o... 124 | 124
Multiple sclerosis 124 | 124
Cholesterol, total 123 | 123
Night sleep phenotypes 123 | 123
Lung cancer 122 | 122
Lymphocyte percentage of white... 122 | 122
Menarche (age at onset) 122 | 122
Neutrophil percentage of white... 121 | 121
Rheumatoid arthritis 121 | 121
Systolic blood pressure 120 | 120
Immature fraction of reticuloc... 118 | 118
Diisocyanate-induced asthma 116 | 116
HDL cholesterol 116 | 116
Allergic disease (asthma, hay ... 115 | 115
Educational attainment (years ... 114 | 114
Hematocrit 113 | 113
Hemoglobin concentration 112 | 112
LDL cholesterol 110 | 110
QT interval 110 | 110
Waist circumference adjusted f... 110 | 110
Mosquito bite size 107 | 107
Asthma 106 | 106
Lobe attachment (rater-scored ... 103 | 103
Peripheral arterial disease (t... 101 | 101
Pulse pressure 97 | 97
Bipolar disorder 94 | 94
Major depressive disorder 94 | 94
Prostate cancer 92 | 92
Parkinson's disease 90 | 90
Hip circumference adjusted for... 89 | 89
Metabolite levels 87 | 87
Triglycerides 87 | 87
Colonoscopy-negative controls ... 85 | 85
Mean corpuscular hemoglobin co... 85 | 85
Itch intensity from mosquito b... 84 | 84
Bipolar disorder and schizophr... 83 | 83
Resting heart rate 82 | 82
Macrophage inflammatory protei... 81 | 81
Migraine 81 | 81
Waist-to-hip ratio adjusted fo... 81 | 81
PR interval in Tripanosoma cru... 80 | 80
Cognitive performance 79 | 79
Glomerular filtration rate (cr... 78 | 78
Late-onset Alzheimer's disease 78 | 78
Waist circumference adjusted f... 75 | 75
Tuberculosis 73 | 73
Type 1 diabetes 73 | 73
Morning vs. evening chronotype 72 | 72

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Transcription regulator protein BACH2 BACH2 Tbio Transcription Factor -1.90906 89.8 184
Protein FAM57B FAM57B Tdark Non-IDG 0.48 0.62 20
Forkhead box protein O1 FOXO1 Tbio Transcription Factor -3.05358 1143.3 1478
NEDD4 family-interacting protein 1 NDFIP1 Tbio Non-IDG -1.24333 24.3 147
Juxtaposed with another zinc finger protein 1 JAZF1 Tbio Non-IDG -1.61585 42.8 94
Serpin B12 SERPINB12 Tbio Non-IDG -0.56624 4.27 155
Mitochondrial peptide methionine sulfoxide reductase MSRA Tbio Enzyme -1.92325 88.1 167
Suppressor of tumorigenicity 20 protein ST20 Tdark Non-IDG -1.66163 0.71 0
Transcriptional-regulating factor 1 TRERF1 Tbio Transcription Factor -0.69436 6.18 146
5-hydroxytryptamine receptor 4 HTR4 Tclin GPCR -2.87235 796.4 248