Development Level

Tbio 92 | 11,445
Tdark 14 | 6,588
Tchem 5 | 1,598
Tclin 3 | 613

Collection

Kinase: IDG Consortium (Target... 1 | 125

IMPC Phenotype

preweaning lethality, complete... 10 | 979
abnormal bone structure 8 | 187
abnormal behavior 6 | 298
decreased grip strength 6 | 116
decreased bone mineral content 5 | 151
decreased lean body mass 5 | 135
decreased total body fat amoun... 5 | 207
increased lean body mass 5 | 172
increased total body fat amoun... 5 | 134
preweaning lethality, incomple... 5 | 499
decreased caudal vertebrae num... 4 | 53
embryonic lethality prior to t... 4 | 278
abnormal embryo size 3 | 220
abnormal epididymis morphology 3 | 42
abnormal heart morphology 3 | 162
abnormal lens morphology 3 | 81
cataract 3 | 92
decreased circulating alkaline... 3 | 46
decreased circulating insulin ... 3 | 76
decreased circulating serum al... 3 | 82
decreased circulating triglyce... 3 | 79
decreased fasted circulating g... 3 | 65
embryonic lethality prior to o... 3 | 239
enlarged heart 3 | 210
hypoactivity 3 | 132
impaired glucose tolerance 3 | 75
increased bone mineral content 3 | 108
increased circulating alkaline... 3 | 122
increased fasted circulating g... 3 | 76
polycystic kidney 3 | 15
short tibia 3 | 97
abnormal embryo turning 2 | 31
abnormal gait 2 | 69
abnormal kidney morphology 2 | 65
abnormal locomotor behavior 2 | 24
abnormal seminal vesicle morph... 2 | 114
decreased blood urea nitrogen ... 2 | 51
decreased body length 2 | 101
decreased circulating HDL chol... 2 | 68
decreased circulating choleste... 2 | 93
decreased exploration in new e... 2 | 11
decreased lymphocyte cell numb... 2 | 83
decreased prepulse inhibition 2 | 82
decreased pulmonary respirator... 2 | 5
decreased startle reflex 2 | 75
decreased vertical activity 2 | 208
enlarged epididymis 2 | 31
enlarged stomach 2 | 2
increased circulating amylase ... 2 | 25
increased circulating chloride... 2 | 41
increased hematocrit 2 | 46
increased or absent threshold ... 2 | 101
increased red blood cell distr... 2 | 34
limb grasping 2 | 41
small thymus 2 | 16
tremors 2 | 39
vertebral transformation 2 | 12
abnormal behavioral response t... 1 | 66
abnormal cornea morphology 1 | 31
abnormal craniofacial morpholo... 1 | 33
abnormal cranium morphology 1 | 36
abnormal eye morphology 1 | 68
abnormal forebrain development 1 | 20
abnormal heart left ventricle ... 1 | 16
abnormal hindbrain development 1 | 16
abnormal iris morphology 1 | 13
abnormal midbrain development 1 | 20
abnormal neural tube closure 1 | 46
abnormal optic disc morphology 1 | 10
abnormal sleep behavior 1 | 70
abnormal testis morphology 1 | 43
abnormal tooth morphology 1 | 24
abnormal urinary bladder morph... 1 | 11
absent pinna reflex 1 | 23
anophthalmia 1 | 33
corneal opacity 1 | 32
cystolithiasis 1 | 3
decreased bone mineral density 1 | 126
decreased circulating amylase ... 1 | 28
decreased circulating calcium ... 1 | 36
dilated heart left ventricle 1 | 11
enlarged adrenal glands 1 | 3
enlarged uterus 1 | 11
hydrometra 1 | 53
hyperactivity 1 | 148
increased circulating iron lev... 1 | 30
increased circulating potassiu... 1 | 29
increased coping response 1 | 4
increased exploration in new e... 1 | 8
increased heart rate 1 | 23
increased heart weight 1 | 62
increased leukocyte cell numbe... 1 | 47
increased mean corpuscular hem... 1 | 96
increased vertical activity 1 | 24
microphthalmia 1 | 26
persistence of hyaloid vascula... 1 | 33
prenatal lethality prior to he... 1 | 87
small spleen 1 | 19
small testis 1 | 58
thick skin 1 | 4

Disease

Carcinoma 88 | 11,493
medulloblastoma, large-cell 62 | 6,241
ovarian cancer 59 | 8,520
atypical teratoid / rhabdoid tumor 54 | 5,112
osteosarcoma 54 | 7,950
glioblastoma 53 | 5,792
ependymoma 50 | 4,679
psoriasis 47 | 6,694
adult high grade glioma 43 | 3,801
group 3 medulloblastoma 43 | 4,104
Kidney cancer 36 | 2,613
oligodendroglioma 36 | 2,850
lung cancer 35 | 4,740
Astrocytoma, Pilocytic 33 | 3,081
Breast cancer 33 | 3,578
intraductal papillary-mucinous carcinoma (IPMC) 32 | 2,989
astrocytic glioma 31 | 2,597
intraductal papillary-mucinous adenoma (IPMA) 27 | 2,955
lung carcinoma 27 | 2,843
subependymal giant cell astrocytoma 26 | 2,287
interstitial cystitis 25 | 2,312
intraductal papillary-mucinous neoplasm (IPMN) 25 | 3,291
invasive ductal carcinoma 25 | 2,951
lung adenocarcinoma 25 | 2,716
primitive neuroectodermal tumor 25 | 3,035
pituitary cancer 23 | 1,972
group 4 medulloblastoma 22 | 1,855
malignant mesothelioma 21 | 3,232
pancreatic cancer 20 | 2,398
Pick disease 19 | 1,894
Schizophrenia 19 | 1,160
non-small cell lung cancer 18 | 2,890
cystic fibrosis 17 | 1,696
astrocytoma 16 | 1,146
breast carcinoma 16 | 1,638
Intellectual disability 15 | 1,016
tuberculosis 15 | 2,010
ulcerative colitis 15 | 1,819
Autistic Disorder 14 | 364
Cancer 14 | 2,499
Rheumatoid arthritis 14 | 1,191
pancreatic ductal adenocarcinoma liver metastasis 14 | 1,962
juvenile dermatomyositis 13 | 1,187
Bipolar Disorder 12 | 666
colon cancer 12 | 1,478
adrenocortical carcinoma 11 | 1,428
ductal carcinoma in situ 11 | 1,745
Epilepsy 10 | 792
Alzheimer's disease 9 | 658
Obesity 9 | 678
dermatomyositis 9 | 966
Autosomal recessive predisposition 8 | 1,442
Melanoma 8 | 711
Skin cancer 8 | 469
active Crohn's disease 8 | 922
cutaneous lupus erythematosus 8 | 1,057
primary pancreatic ductal adenocarcinoma 8 | 1,109
spina bifida 8 | 1,074
Acquired metabolic disease 7 | 336
Amyotrophic lateral sclerosis 7 | 451
Atopic dermatitis 7 | 952
Autism spectrum disorder 7 | 101
Endometrial cancer 7 | 311
Liver cancer 7 | 604
Multiple myeloma 7 | 1,332
Muscle hypotonia 7 | 571
Autism Spectrum Disorders 6 | 75
Depressive disorder 6 | 409
Dull intelligence 6 | 645
Low intelligence 6 | 645
Mental Depression 6 | 333
Mental Retardation 6 | 645
Mental deficiency 6 | 645
Poor school performance 6 | 645
Vascular disease 6 | 319
active ulcerative colitis 6 | 764
acute myeloid leukemia 6 | 783
acute quadriplegic myopathy 6 | 1,158
aldosterone-producing adenoma 6 | 665
autosomal dominant Emery-Dreifuss muscular dystrophy 6 | 510
diabetes mellitus 6 | 1,728
gastric cancer 6 | 459
tuberculosis and treatment for 6 months 6 | 409
Adenoid Cystic Carcinoma 5 | 99
Carcinoma, Adenoid Cystic 5 | 99
Crohn's disease 5 | 321
Down syndrome 5 | 499
Language Development Disorders 5 | 11
Osteoporosis 5 | 363
Parkinson's disease 5 | 392
Prostatic Neoplasms 5 | 495
Seizures 5 | 596
esophageal adenocarcinoma 5 | 737
interstitial lung disease 5 | 298
nasopharyngeal carcinoma 5 | 1,058
non primary Sjogren syndrome sicca 5 | 891
pancreatic carcinoma 5 | 562
pediatric high grade glioma 5 | 1,064
primary Sjogren syndrome 5 | 735
progressive supranuclear palsy 5 | 676

Tissue

Endocrine System 109 | 18,159
Skin and soft tissues 107 | 17,230
Nervous System 106 | 16,725
Digestive Tract 105 | 17,369
Female tissues 104 | 17,400
Male tissues 104 | 17,142
Respiratory system 103 | 16,393
Blood and immune system 101 | 16,909
Liver and Pancreas 101 | 16,750
Urinary Tract 101 | 16,678
Cardiovascular System 96 | 15,192

Target Family

Non-IDG 63 | 12,091
Enzyme 22 | 4,145
Transcription Factor 17 | 1,400
Kinase 4 | 634
GPCR 2 | 408
Ion Channel 2 | 344
Transporter 2 | 473
Epigenetic 1 | 242
Nuclear Receptor 1 | 48

GWAS Trait

Educational attainment (years ... 114 | 114
Obesity-related traits 569 | 569
Schizophrenia 533 | 533
Breast cancer 492 | 492
Body mass index 379 | 379
Height 369 | 369
Coronary artery disease 367 | 367
Blood protein levels 351 | 351
Post bronchodilator FEV1-FVC r... 308 | 308
Mean corpuscular volume 283 | 283
Platelet count 275 | 275
Intelligence (multi-trait anal... 267 | 267
Mean platelet volume 253 | 253
IgG glycosylation 250 | 250
Mean corpuscular hemoglobin 238 | 238
Inflammatory bowel disease 235 | 235
Plateletcrit 227 | 227
Crohn's disease 215 | 215
Type 2 diabetes 210 | 210
Red blood cell count 191 | 191
Monocyte count 183 | 183
Red cell distribution width 182 | 182
Eosinophil counts 180 | 180
Neuroticism 180 | 180
Platelet distribution width 174 | 174
Monocyte percentage of white c... 173 | 173
Post bronchodilator FEV1 173 | 173
Sum eosinophil basophil counts 173 | 173
White blood cell count 172 | 172
3-hydroxy-1-methylpropylmercap... 166 | 166
Eosinophil percentage of granu... 163 | 163
Eosinophil percentage of white... 163 | 163
Reticulocyte fraction of red c... 163 | 163
Ulcerative colitis 163 | 163
Granulocyte percentage of myel... 162 | 162
Itch intensity from mosquito b... 162 | 162
Systemic lupus erythematosus 159 | 159
High light scatter reticulocyt... 158 | 158
Lymphocyte counts 158 | 158
Reticulocyte count 158 | 158
Blood metabolite levels 157 | 157
Neutrophil count 154 | 154
High light scatter reticulocyt... 153 | 153
Neutrophil percentage of granu... 153 | 153
3-hydroxypropylmercapturic aci... 150 | 150
Tonsillectomy 149 | 149
Diastolic blood pressure 144 | 144
Sum basophil neutrophil counts 140 | 140
Autism spectrum disorder or sc... 134 | 134
Myeloid white cell count 133 | 133
Granulocyte count 132 | 132
Sum neutrophil eosinophil coun... 129 | 129
Colorectal cancer 126 | 126
Alzheimer disease and age of o... 124 | 124
Multiple sclerosis 124 | 124
Cholesterol, total 123 | 123
Night sleep phenotypes 123 | 123
Lung cancer 122 | 122
Lymphocyte percentage of white... 122 | 122
Menarche (age at onset) 122 | 122
Neutrophil percentage of white... 121 | 121
Rheumatoid arthritis 121 | 121
Systolic blood pressure 120 | 120
Immature fraction of reticuloc... 118 | 118
Diisocyanate-induced asthma 116 | 116
HDL cholesterol 116 | 116
Allergic disease (asthma, hay ... 115 | 115
Hematocrit 113 | 113
Hemoglobin concentration 112 | 112
LDL cholesterol 110 | 110
QT interval 110 | 110
Waist circumference adjusted f... 110 | 110
Mosquito bite size 107 | 107
Asthma 106 | 106
Lobe attachment (rater-scored ... 103 | 103
Peripheral arterial disease (t... 101 | 101
Pulse pressure 97 | 97
Bipolar disorder 94 | 94
Major depressive disorder 94 | 94
Prostate cancer 92 | 92
Parkinson's disease 90 | 90
Hip circumference adjusted for... 89 | 89
Metabolite levels 87 | 87
Triglycerides 87 | 87
Colonoscopy-negative controls ... 85 | 85
Mean corpuscular hemoglobin co... 85 | 85
Itch intensity from mosquito b... 84 | 84
Bipolar disorder and schizophr... 83 | 83
Resting heart rate 82 | 82
Macrophage inflammatory protei... 81 | 81
Migraine 81 | 81
Waist-to-hip ratio adjusted fo... 81 | 81
PR interval in Tripanosoma cru... 80 | 80
Cognitive performance 79 | 79
Glomerular filtration rate (cr... 78 | 78
Late-onset Alzheimer's disease 78 | 78
Waist circumference adjusted f... 75 | 75
Tuberculosis 73 | 73
Type 1 diabetes 73 | 73
Morning vs. evening chronotype 72 | 72

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Adenylate kinase isoenzyme 5 AK5 Tbio Kinase -1.83209 76.0 225
Neurexin-1 NRXN1 Tbio Non-IDG -1.88807 125.1 174
Epithelial membrane protein 1 EMP1 Tbio Non-IDG -2.60119 387.7 88
Zinc transporter 1 SLC30A1 Tbio Transporter -2.12639 135.9 148
SKI family transcriptional corepressor 2 SKOR2 Tbio Non-IDG -0.52843 4.42 59
Putative uncharacterized protein encoded by LINC01559 LINC01559 Tdark Non-IDG 0.00000 0
BarH-like 2 homeobox protein BARHL2 Tbio Transcription Factor -0.91713 9.51 53
Putative uncharacterized protein encoded by LINC00467 LINC00467 Tdark Non-IDG 0.00000 0
Endosialin CD248 Tbio Non-IDG -3.07620 1180.8 253
Forkhead box protein O6 FOXO6 Tbio Transcription Factor -1.13890 17.2 38