Development Level

Tbio 39 | 11,445
Tdark 7 | 6,588
Tchem 6 | 1,598
Tclin 2 | 613

Collection

Kinase: IDG Consortium (Target... 2 | 125

IMPC Phenotype

preweaning lethality, complete... 4 | 979
decreased caudal vertebrae num... 2 | 53
decreased circulating insulin ... 2 | 76
decreased circulating serum al... 2 | 82
decreased grip strength 2 | 116
impaired glucose tolerance 2 | 75
preweaning lethality, incomple... 2 | 499
vertebral transformation 2 | 12
abnormal behavior 1 | 298
abnormal bone structure 1 | 187
abnormal cornea morphology 1 | 31
abnormal cranium morphology 1 | 36
abnormal epididymis morphology 1 | 42
abnormal eye morphology 1 | 68
abnormal gait 1 | 69
abnormal heart morphology 1 | 162
abnormal incisor morphology 1 | 4
abnormal iris morphology 1 | 13
abnormal lens morphology 1 | 81
abnormal optic disc morphology 1 | 10
abnormal retina morphology 1 | 71
abnormal retinal blood vessel ... 1 | 26
abnormal seminal vesicle morph... 1 | 114
abnormal testis morphology 1 | 43
abnormal vertebral arch morpho... 1 | 9
abnormal vibrissa morphology 1 | 25
absent pinna reflex 1 | 23
cataract 1 | 92
corneal opacity 1 | 32
decreased circulating alkaline... 1 | 46
decreased circulating calcium ... 1 | 36
decreased circulating fructosa... 1 | 30
decreased circulating glycerol... 1 | 16
decreased erythrocyte cell num... 1 | 62
decreased threshold for audito... 1 | 26
enlarged epididymis 1 | 31
enlarged heart 1 | 210
fused cornea and lens 1 | 5
fusion of vertebral arches 1 | 7
head bobbing 1 | 5
improved glucose tolerance 1 | 79
increased blood urea nitrogen ... 1 | 48
increased circulating creatini... 1 | 38
increased circulating iron lev... 1 | 30
increased circulating potassiu... 1 | 29
increased erythrocyte cell num... 1 | 39
increased hematocrit 1 | 46
increased mean corpuscular hem... 1 | 96
increased or absent threshold ... 1 | 101
increased prepulse inhibition 1 | 32
mydriasis 1 | 6
persistence of hyaloid vascula... 1 | 33
small testis 1 | 58

Disease

Carcinoma 47 | 11,493
medulloblastoma, large-cell 30 | 6,241
ovarian cancer 30 | 8,520
glioblastoma 25 | 5,792
osteosarcoma 25 | 7,950
atypical teratoid / rhabdoid tumor 24 | 5,112
ependymoma 22 | 4,679
psoriasis 21 | 6,694
adult high grade glioma 20 | 3,801
Kidney cancer 18 | 2,613
intraductal papillary-mucinous adenoma (IPMA) 18 | 2,955
Astrocytoma, Pilocytic 17 | 3,081
intraductal papillary-mucinous carcinoma (IPMC) 17 | 2,989
lung cancer 17 | 4,740
group 3 medulloblastoma 14 | 4,104
subependymal giant cell astrocytoma 14 | 2,287
cystic fibrosis 13 | 1,696
lung adenocarcinoma 13 | 2,716
pituitary cancer 13 | 1,972
primitive neuroectodermal tumor 13 | 3,035
Breast cancer 12 | 3,578
Pick disease 12 | 1,894
astrocytic glioma 12 | 2,597
intraductal papillary-mucinous neoplasm (IPMN) 12 | 3,291
oligodendroglioma 12 | 2,850
group 4 medulloblastoma 11 | 1,855
pancreatic cancer 11 | 2,398
ulcerative colitis 11 | 1,819
interstitial cystitis 10 | 2,312
malignant mesothelioma 10 | 3,232
Schizophrenia 9 | 1,160
non-small cell lung cancer 9 | 2,890
Rheumatoid arthritis 8 | 1,191
lung carcinoma 8 | 2,843
pancreatic ductal adenocarcinoma liver metastasis 8 | 1,962
tuberculosis 8 | 2,010
Cancer 7 | 2,499
Obesity 7 | 678
astrocytoma 7 | 1,146
diabetes mellitus 7 | 1,728
invasive ductal carcinoma 7 | 2,951
Acquired metabolic disease 6 | 336
Autistic Disorder 6 | 364
Mental Depression 6 | 333
Autosomal recessive predisposition 5 | 1,442
Epilepsy 5 | 792
Intellectual disability 5 | 1,016
adrenocortical carcinoma 5 | 1,428
autosomal dominant Emery-Dreifuss muscular dystrophy 5 | 510
breast carcinoma 5 | 1,638
interstitial lung disease 5 | 298
nasopharyngeal carcinoma 5 | 1,058
progressive supranuclear palsy 5 | 676
spina bifida 5 | 1,074
Bipolar Disorder 4 | 666
Breast Neoplasms 4 | 445
Depressive disorder 4 | 409
Down syndrome 4 | 499
Liver cancer 4 | 604
Mammary Neoplasms 4 | 425
acute quadriplegic myopathy 4 | 1,158
aldosterone-producing adenoma 4 | 665
colon cancer 4 | 1,478
ductal carcinoma in situ 4 | 1,745
juvenile dermatomyositis 4 | 1,187
medulloblastoma 4 | 720
pediatric high grade glioma 4 | 1,064
Alzheimer's disease 3 | 658
Arthritis, Juvenile 3 | 126
Barrett's esophagus 3 | 182
Cognitive delay 3 | 608
Duchenne muscular dystrophy 3 | 601
Global developmental delay 3 | 608
Hypertension 3 | 396
Juvenile arthritis 3 | 126
Mental and motor retardation 3 | 608
Osteoporosis 3 | 363
Squamous cell carcinoma 3 | 129
cutaneous lupus erythematosus 3 | 1,057
head and neck cancer 3 | 271
non primary Sjogren syndrome sicca 3 | 891
pancreatic carcinoma 3 | 562
posterior fossa group A ependymoma 3 | 468
primary Sjogren syndrome 3 | 735
sonic hedgehog group medulloblastoma 3 | 467
Anorexia nervosa 2 | 80
Atherosclerosis 2 | 291
Atopic dermatitis 2 | 952
Chronic obstructive pulmonary disease 2 | 184
Diabetes Mellitus, Non-Insulin-Dependent 2 | 145
Diabetes Mellitus, Type 2 2 | 142
Endometrial cancer 2 | 311
Endometriosis 2 | 540
Glaucoma 2 | 239
Prostatic Neoplasms 2 | 495
Seizures 2 | 596
Stomach Neoplasms 2 | 300
Vascular disease 2 | 319
active Crohn's disease 2 | 922
primary pancreatic ductal adenocarcinoma 2 | 1,109

Tissue

Endocrine System 52 | 18,159
Skin and soft tissues 50 | 17,230
Digestive Tract 49 | 17,369
Urinary Tract 49 | 16,678
Blood and immune system 48 | 16,909
Female tissues 48 | 17,400
Male tissues 48 | 17,142
Nervous System 48 | 16,725
Cardiovascular System 46 | 15,192
Respiratory system 46 | 16,393
Liver and Pancreas 45 | 16,750

Target Family

Non-IDG 27 | 12,091
Enzyme 12 | 4,145
Transcription Factor 6 | 1,400
Kinase 5 | 634
Ion Channel 2 | 344
Epigenetic 1 | 242
GPCR 1 | 408

GWAS Trait

Educational attainment 54 | 54
Obesity-related traits 569 | 569
Schizophrenia 533 | 533
Breast cancer 492 | 492
Body mass index 379 | 379
Height 369 | 369
Coronary artery disease 367 | 367
Blood protein levels 351 | 351
Post bronchodilator FEV1-FVC r... 308 | 308
Mean corpuscular volume 283 | 283
Platelet count 275 | 275
Intelligence (multi-trait anal... 267 | 267
Mean platelet volume 253 | 253
IgG glycosylation 250 | 250
Mean corpuscular hemoglobin 238 | 238
Inflammatory bowel disease 235 | 235
Plateletcrit 227 | 227
Crohn's disease 215 | 215
Type 2 diabetes 210 | 210
Red blood cell count 191 | 191
Monocyte count 183 | 183
Red cell distribution width 182 | 182
Eosinophil counts 180 | 180
Neuroticism 180 | 180
Platelet distribution width 174 | 174
Monocyte percentage of white c... 173 | 173
Post bronchodilator FEV1 173 | 173
Sum eosinophil basophil counts 173 | 173
White blood cell count 172 | 172
3-hydroxy-1-methylpropylmercap... 166 | 166
Eosinophil percentage of granu... 163 | 163
Eosinophil percentage of white... 163 | 163
Reticulocyte fraction of red c... 163 | 163
Ulcerative colitis 163 | 163
Granulocyte percentage of myel... 162 | 162
Itch intensity from mosquito b... 162 | 162
Systemic lupus erythematosus 159 | 159
High light scatter reticulocyt... 158 | 158
Lymphocyte counts 158 | 158
Reticulocyte count 158 | 158
Blood metabolite levels 157 | 157
Neutrophil count 154 | 154
High light scatter reticulocyt... 153 | 153
Neutrophil percentage of granu... 153 | 153
3-hydroxypropylmercapturic aci... 150 | 150
Tonsillectomy 149 | 149
Diastolic blood pressure 144 | 144
Sum basophil neutrophil counts 140 | 140
Autism spectrum disorder or sc... 134 | 134
Myeloid white cell count 133 | 133
Granulocyte count 132 | 132
Sum neutrophil eosinophil coun... 129 | 129
Colorectal cancer 126 | 126
Alzheimer disease and age of o... 124 | 124
Multiple sclerosis 124 | 124
Cholesterol, total 123 | 123
Night sleep phenotypes 123 | 123
Lung cancer 122 | 122
Lymphocyte percentage of white... 122 | 122
Menarche (age at onset) 122 | 122
Neutrophil percentage of white... 121 | 121
Rheumatoid arthritis 121 | 121
Systolic blood pressure 120 | 120
Immature fraction of reticuloc... 118 | 118
Diisocyanate-induced asthma 116 | 116
HDL cholesterol 116 | 116
Allergic disease (asthma, hay ... 115 | 115
Educational attainment (years ... 114 | 114
Hematocrit 113 | 113
Hemoglobin concentration 112 | 112
LDL cholesterol 110 | 110
QT interval 110 | 110
Waist circumference adjusted f... 110 | 110
Mosquito bite size 107 | 107
Asthma 106 | 106
Lobe attachment (rater-scored ... 103 | 103
Peripheral arterial disease (t... 101 | 101
Pulse pressure 97 | 97
Bipolar disorder 94 | 94
Major depressive disorder 94 | 94
Prostate cancer 92 | 92
Parkinson's disease 90 | 90
Hip circumference adjusted for... 89 | 89
Metabolite levels 87 | 87
Triglycerides 87 | 87
Colonoscopy-negative controls ... 85 | 85
Mean corpuscular hemoglobin co... 85 | 85
Itch intensity from mosquito b... 84 | 84
Bipolar disorder and schizophr... 83 | 83
Resting heart rate 82 | 82
Macrophage inflammatory protei... 81 | 81
Migraine 81 | 81
Waist-to-hip ratio adjusted fo... 81 | 81
PR interval in Tripanosoma cru... 80 | 80
Cognitive performance 79 | 79
Glomerular filtration rate (cr... 78 | 78
Late-onset Alzheimer's disease 78 | 78
Waist circumference adjusted f... 75 | 75
Tuberculosis 73 | 73
Type 1 diabetes 73 | 73
Morning vs. evening chronotype 72 | 72

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Beta-secretase 2 BACE2 Tchem Enzyme -2.09709 114.0 418
SKI family transcriptional corepressor 2 SKOR2 Tbio Non-IDG -0.52843 4.42 59
Serine/threonine-protein kinase 24 STK24 Tchem Kinase -2.24110 132.9 243
BarH-like 2 homeobox protein BARHL2 Tbio Transcription Factor -0.91713 9.51 53
LHFPL tetraspan subfamily member 3 protein LHFPL3 Tdark Non-IDG -0.42390 2.31 47
AF4/FMR2 family member 3 AFF3 Tbio Transcription Factor -1.37981 25.3 50
Arf-GAP with GTPase, ANK repeat and PH domain-containing protein 1 AGAP1 Tbio Enzyme -0.83079 8.71 94
E3 ubiquitin-protein ligase RNF123 RNF123 Tbio Enzyme -1.29797 18.7 77
Ataxin-2-like protein ATXN2L Tbio Non-IDG -1.58925 37.9 93
CUGBP Elav-like family member 4 CELF4 Tbio Non-IDG -1.58928 38.2 56