Development Level

Tbio 7 | 11,445

IMPC Phenotype

decreased KLRG1+ CD8 alpha bet... 1 | 2
decreased bone mineral content 1 | 151
decreased lean body mass 1 | 135
decreased neutrophil cell numb... 1 | 42
decreased red blood cell distr... 1 | 41
preweaning lethality, complete... 1 | 979

Disease

ependymoma 6 | 4,679
Carcinoma 5 | 11,493
Anorexia nervosa 4 | 80
Kidney cancer 4 | 2,613
adult high grade glioma 4 | 3,801
atypical teratoid / rhabdoid tumor 4 | 5,112
glioblastoma 4 | 5,792
lung carcinoma 4 | 2,843
non-small cell lung cancer 4 | 2,890
osteosarcoma 4 | 7,950
ovarian cancer 4 | 8,520
Astrocytoma, Pilocytic 3 | 3,081
Bipolar Disorder 3 | 666
Breast cancer 3 | 3,578
Liver cancer 3 | 604
Schizophrenia 3 | 1,160
medulloblastoma, large-cell 3 | 6,241
oligodendroglioma 3 | 2,850
pancreatic cancer 3 | 2,398
tuberculosis 3 | 2,010
Asthma 2 | 385
Melanoma 2 | 711
Skin cancer 2 | 469
cystic fibrosis 2 | 1,696
group 3 medulloblastoma 2 | 4,104
head and neck cancer 2 | 271
interstitial cystitis 2 | 2,312
intraductal papillary-mucinous neoplasm (IPMN) 2 | 3,291
lung adenocarcinoma 2 | 2,716
pituitary cancer 2 | 1,972
primitive neuroectodermal tumor 2 | 3,035
psoriasis 2 | 6,694
11 pairs of ribs 1 | 7
Abnormal development of end part of bone 1 | 14
Abnormality of the humerus 1 | 6
Abnormality of the metacarpal bones 1 | 17
Abnormality of the tibia 1 | 9
Acquired flat foot 1 | 72
Alcohol abuse 1 | 50
Aplasia/Hypoplasia of the abdominal wall musculature 1 | 17
Aplasia/Hypoplasia of the lungs 1 | 13
Beaked vertebral bodies 1 | 9
Brachyonychia 1 | 6
Broad distal phalanges 1 | 2
Broad face 1 | 7
Bronchomalacia 1 | 7
Chikungunya 1 | 16
Colitis, Ulcerative 1 | 59
Compression of spinal cord 1 | 10
Congenital hypoplasia of femur 1 | 8
Congenital pectus carinatum 1 | 52
Coronal cleft vertebrae 1 | 8
DOID:9917 1 | 31
Defective enamel matrix 1 | 35
Diabetes Mellitus, Insulin-Dependent 1 | 48
Diabetes Mellitus, Type 1 1 | 43
Dilatation of aorta 1 | 9
Epiphyseal dysplasia 1 | 14
Equinovalgus deformity 1 | 4
Flat acetabular roof 1 | 10
Flatfoot 1 | 73
Fused cervical vertebrae 1 | 5
Gastroenteritis 1 | 41
Graves' disease 1 | 24
Hearing Loss, Mixed Conductive-Sensorineural 1 | 12
Hitchhiker thumb 1 | 3
Horizontal sacrum 1 | 3
Hydrops Fetalis 1 | 21
Hypoplastic iliac body 1 | 2
Isolated somatotropin deficiency 1 | 30
Joint laxity 1 | 54
Larsen syndrome 1 | 10
Liver Diseases, Parasitic 1 | 9
Neonatal Death 1 | 14
ODONTOID HYPOPLASIA 1 | 16
Proximal club shaped femurs 1 | 2
Restrictive lung disease 1 | 11
Restrictive ventilatory defect 1 | 11
Sandal gap 1 | 24
Severe short-limb dwarfism 1 | 4
Shallow orbits 1 | 13
Short distal phalanges 1 | 50
Short metatarsal 1 | 21
Sickle Cell Anemia 1 | 53
Spatulate thumbs 1 | 3
Spondyloepiphyseal dysplasia with congenital joint dislocations 1 | 13
Spondylolysis 1 | 14
Stiff-Person syndrome 1 | 12
Stillbirth 1 | 17
Talipes Equinovalgus 1 | 4
Tarsal Coalition 1 | 12
Thin hypoplastic alae nasi 1 | 51
Tibial bowing 1 | 19
Tracheal stenosis 1 | 23
Venezuelan equine encephalitis 1 | 7
Vesico-Ureteral Reflux 1 | 33
Vesicoureteral Reflux 2 1 | 1
Vesicoureteral reflux 1 | 32
Wedging of vertebra 1 | 9
Western equine encephalitis 1 | 13

Tissue

Blood and immune system 6 | 16,909
Digestive Tract 6 | 17,369
Endocrine System 6 | 18,159
Female tissues 6 | 17,400
Liver and Pancreas 6 | 16,750
Male tissues 6 | 17,142
Nervous System 6 | 16,725
Respiratory system 6 | 16,393
Skin and soft tissues 6 | 17,230
Urinary Tract 6 | 16,678
Cardiovascular System 5 | 15,192

Target Family

Non-IDG 6 | 12,091
Enzyme 1 | 4,145

GWAS Trait

Eating disorders (purging via ... 7 | 7
Obesity-related traits 569 | 569
Schizophrenia 533 | 533
Breast cancer 492 | 492
Body mass index 379 | 379
Height 369 | 369
Coronary artery disease 367 | 367
Blood protein levels 351 | 351
Post bronchodilator FEV1-FVC r... 308 | 308
Mean corpuscular volume 283 | 283
Platelet count 275 | 275
Intelligence (multi-trait anal... 267 | 267
Mean platelet volume 253 | 253
IgG glycosylation 250 | 250
Mean corpuscular hemoglobin 238 | 238
Inflammatory bowel disease 235 | 235
Plateletcrit 227 | 227
Crohn's disease 215 | 215
Type 2 diabetes 210 | 210
Red blood cell count 191 | 191
Monocyte count 183 | 183
Red cell distribution width 182 | 182
Eosinophil counts 180 | 180
Neuroticism 180 | 180
Platelet distribution width 174 | 174
Monocyte percentage of white c... 173 | 173
Post bronchodilator FEV1 173 | 173
Sum eosinophil basophil counts 173 | 173
White blood cell count 172 | 172
3-hydroxy-1-methylpropylmercap... 166 | 166
Eosinophil percentage of granu... 163 | 163
Eosinophil percentage of white... 163 | 163
Reticulocyte fraction of red c... 163 | 163
Ulcerative colitis 163 | 163
Granulocyte percentage of myel... 162 | 162
Itch intensity from mosquito b... 162 | 162
Systemic lupus erythematosus 159 | 159
High light scatter reticulocyt... 158 | 158
Lymphocyte counts 158 | 158
Reticulocyte count 158 | 158
Blood metabolite levels 157 | 157
Neutrophil count 154 | 154
High light scatter reticulocyt... 153 | 153
Neutrophil percentage of granu... 153 | 153
3-hydroxypropylmercapturic aci... 150 | 150
Tonsillectomy 149 | 149
Diastolic blood pressure 144 | 144
Sum basophil neutrophil counts 140 | 140
Autism spectrum disorder or sc... 134 | 134
Myeloid white cell count 133 | 133
Granulocyte count 132 | 132
Sum neutrophil eosinophil coun... 129 | 129
Colorectal cancer 126 | 126
Alzheimer disease and age of o... 124 | 124
Multiple sclerosis 124 | 124
Cholesterol, total 123 | 123
Night sleep phenotypes 123 | 123
Lung cancer 122 | 122
Lymphocyte percentage of white... 122 | 122
Menarche (age at onset) 122 | 122
Neutrophil percentage of white... 121 | 121
Rheumatoid arthritis 121 | 121
Systolic blood pressure 120 | 120
Immature fraction of reticuloc... 118 | 118
Diisocyanate-induced asthma 116 | 116
HDL cholesterol 116 | 116
Allergic disease (asthma, hay ... 115 | 115
Educational attainment (years ... 114 | 114
Hematocrit 113 | 113
Hemoglobin concentration 112 | 112
LDL cholesterol 110 | 110
QT interval 110 | 110
Waist circumference adjusted f... 110 | 110
Mosquito bite size 107 | 107
Asthma 106 | 106
Lobe attachment (rater-scored ... 103 | 103
Peripheral arterial disease (t... 101 | 101
Pulse pressure 97 | 97
Bipolar disorder 94 | 94
Major depressive disorder 94 | 94
Prostate cancer 92 | 92
Parkinson's disease 90 | 90
Hip circumference adjusted for... 89 | 89
Metabolite levels 87 | 87
Triglycerides 87 | 87
Colonoscopy-negative controls ... 85 | 85
Mean corpuscular hemoglobin co... 85 | 85
Itch intensity from mosquito b... 84 | 84
Bipolar disorder and schizophr... 83 | 83
Resting heart rate 82 | 82
Macrophage inflammatory protei... 81 | 81
Migraine 81 | 81
Waist-to-hip ratio adjusted fo... 81 | 81
PR interval in Tripanosoma cru... 80 | 80
Cognitive performance 79 | 79
Glomerular filtration rate (cr... 78 | 78
Late-onset Alzheimer's disease 78 | 78
Waist circumference adjusted f... 75 | 75
Tuberculosis 73 | 73
Type 1 diabetes 73 | 73
Morning vs. evening chronotype 72 | 72

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
C-C motif chemokine 20 CCL20 Tbio Non-IDG -3.10283 1250.3 496
Roundabout homolog 2 ROBO2 Tbio Non-IDG -1.89275 74.1 161
CUB and sushi domain-containing protein 1 CSMD1 Tbio Non-IDG -1.68684 47.7 0
Filamin-B FLNB Tbio Non-IDG -2.43075 263.4 168
Ras-specific guanine nucleotide-releasing factor 2 RASGRF2 Tbio Non-IDG -1.31521 23.7 21
SH2 domain-containing protein 3C SH2D3C Tbio Non-IDG -2.11272 127.2 231
Acidic amino acid decarboxylase GADL1 GADL1 Tbio Enzyme -1.55798 36.2 79