Development Level

Tbio 4 | 11,445

IMPC Phenotype

decreased vertical activity 2 | 208
enlarged heart 2 | 210
abnormal heart morphology 1 | 162
abnormal seminal vesicle morph... 1 | 114
embryonic lethality prior to o... 1 | 239
embryonic lethality prior to t... 1 | 278
preweaning lethality, complete... 1 | 979
preweaning lethality, incomple... 1 | 499

Disease

lung cancer 3 | 4,740
psoriasis 3 | 6,694
Autosomal recessive hypohidrotic ectodermal dysplasia syndrome 2 | 3
Carcinoma 2 | 11,493
Ectodermal Dysplasia 10A, Hypohidrotic/Hair/Nail Type, Autosomal Dominant 2 | 3
Hypohidrotic ectodermal dysplasia 2 | 15
Multiple myeloma 2 | 1,332
astrocytoma 2 | 1,146
atypical teratoid / rhabdoid tumor 2 | 5,112
glioblastoma 2 | 5,792
ovarian cancer 2 | 8,520
Abnormality of nail of toe 1 | 11
Abnormality of the fingernails 1 | 51
Acute necrotizing encephalitis 1 | 2
Alopecia 1 | 115
Alzheimer's disease 1 | 658
Anhidrosis 1 | 23
Anodontia 1 | 12
Astrocytoma, Pilocytic 1 | 3,081
Autosomal dominant hypohidrotic ectodermal dysplasia syndrome (disorder) 1 | 3
Autosomal recessive congenital ichthyosis 4B 1 | 13
Autosomal recessive hypohidrotic ectodermal dysplasia 1 | 3
Autosomal recessive predisposition 1 | 1,442
Brain disease 1 | 96
Cataract 8 multiple types 1 | 33
Christ-Siemens-Touraine syndrome 1 | 3
Clouston syndrome 1 | 9
Concave bridge of nose 1 | 195
Decreased size of teeth 1 | 62
Decreased width of tooth 1 | 59
Dental abnormalities 1 | 60
Depressed nasal bridge 1 | 195
Depressed nasal root/bridge 1 | 195
Developmental absence of tooth 1 | 7
Drooping upper lip 1 | 4
Dry skin 1 | 75
ECTODERMAL DYSPLASIA 10B, HYPOHIDROTIC/HAIR/TOOTH TYPE, AUTOSOMAL RECESSIVE 1 | 1
ENCEPHALOPATHY, ACUTE, INFECTION-INDUCED, SUSCEPTIBILITY TO, 3 1 | 1
Ectodermal Dysplasia 1 | 14
Ectodermal Dysplasia 3, Anhidrotic 1 | 2
Ectodermal Dysplasia, Hypohidrotic, Autosomal Recessive 1 | 3
Endometrial cancer 1 | 311
Everted lower lip vermilion 1 | 54
Everted upper lip vermilion 1 | 4
Extratemporal epilepsy 1 | 6
Fine hair 1 | 42
Frontal bossing 1 | 157
Fuhrmann syndrome 1 | 7
Granuloma, Plasma Cell 1 | 2
Hypodontia 1 | 81
Hypohidrosis 1 | 34
Hypotrichosis 1 | 47
Inflammatory myofibroblastic tumor 1 | 8
Influenza 1 | 142
Intolerant of heat 1 | 7
Kidney cancer 1 | 2,613
Large intestine cancer 1 | 126
Microdontia (disorder) 1 | 59
Missing all teeth 1 | 3
Mood Disorders 1 | 184
Nail dysplasia 1 | 52
Periorbital hyperpigmentation 1 | 2
Periorbital wrinkles 1 | 2
Precocious exfoliation of primary tooth 1 | 11
Protruding lower lip 1 | 54
Protruding upper lip 1 | 4
Reye syndrome 1 | 11
Rheumatoid arthritis 1 | 1,191
Slow-growing hair 1 | 19
Sparse eyebrow 1 | 42
Sparse eyelashes 1 | 31
Thick vermilion border 1 | 25
Thyroid Diseases 1 | 24
Tooth Abnormalities 1 | 69
Tooth agenesis 1 | 44
Tooth hypoplasia 1 | 7
Xerosis 1 | 75
acute myeloid leukemia 1 | 783
acute quadriplegic myopathy 1 | 1,158
adrenocortical carcinoma 1 | 1,428
autosomal dominant Emery-Dreifuss muscular dystrophy 1 | 510
breast carcinoma 1 | 1,638
colon cancer 1 | 1,478
dermatomyositis 1 | 966
ependymoma 1 | 4,679
esophageal adenocarcinoma 1 | 737
hereditary spastic paraplegia 1 | 318
interstitial cystitis 1 | 2,312
intraductal papillary-mucinous adenoma (IPMA) 1 | 2,955
intraductal papillary-mucinous carcinoma (IPMC) 1 | 2,989
lung adenocarcinoma 1 | 2,716
lung carcinoma 1 | 2,843
malignant mesothelioma 1 | 3,232
medulloblastoma, large-cell 1 | 6,241
non diabetic and post-ischemic heart failure 1 | 200
non-small cell lung carcinoma 1 | 317
oligodendroglioma 1 | 2,850
sonic hedgehog group medulloblastoma 1 | 467
tuberculosis 1 | 2,010
type II diabetes mellitus and post-ischemic heart failure 1 | 88

Tissue

Blood and immune system 4 | 16,909
Cardiovascular System 4 | 15,192
Digestive Tract 4 | 17,369
Endocrine System 4 | 18,159
Female tissues 4 | 17,400
Liver and Pancreas 4 | 16,750
Male tissues 4 | 17,142
Nervous System 4 | 16,725
Respiratory system 4 | 16,393
Skin and soft tissues 4 | 17,230
Urinary Tract 4 | 16,678

Target Family

Enzyme 2 | 4,145
Non-IDG 2 | 12,091

GWAS Trait

Ear protrusion 4 | 4
Obesity-related traits 569 | 569
Schizophrenia 533 | 533
Breast cancer 492 | 492
Body mass index 379 | 379
Height 369 | 369
Coronary artery disease 367 | 367
Blood protein levels 351 | 351
Post bronchodilator FEV1-FVC r... 308 | 308
Mean corpuscular volume 283 | 283
Platelet count 275 | 275
Intelligence (multi-trait anal... 267 | 267
Mean platelet volume 253 | 253
IgG glycosylation 250 | 250
Mean corpuscular hemoglobin 238 | 238
Inflammatory bowel disease 235 | 235
Plateletcrit 227 | 227
Crohn's disease 215 | 215
Type 2 diabetes 210 | 210
Red blood cell count 191 | 191
Monocyte count 183 | 183
Red cell distribution width 182 | 182
Eosinophil counts 180 | 180
Neuroticism 180 | 180
Platelet distribution width 174 | 174
Monocyte percentage of white c... 173 | 173
Post bronchodilator FEV1 173 | 173
Sum eosinophil basophil counts 173 | 173
White blood cell count 172 | 172
3-hydroxy-1-methylpropylmercap... 166 | 166
Eosinophil percentage of granu... 163 | 163
Eosinophil percentage of white... 163 | 163
Reticulocyte fraction of red c... 163 | 163
Ulcerative colitis 163 | 163
Granulocyte percentage of myel... 162 | 162
Itch intensity from mosquito b... 162 | 162
Systemic lupus erythematosus 159 | 159
High light scatter reticulocyt... 158 | 158
Lymphocyte counts 158 | 158
Reticulocyte count 158 | 158
Blood metabolite levels 157 | 157
Neutrophil count 154 | 154
High light scatter reticulocyt... 153 | 153
Neutrophil percentage of granu... 153 | 153
3-hydroxypropylmercapturic aci... 150 | 150
Tonsillectomy 149 | 149
Diastolic blood pressure 144 | 144
Sum basophil neutrophil counts 140 | 140
Autism spectrum disorder or sc... 134 | 134
Myeloid white cell count 133 | 133
Granulocyte count 132 | 132
Sum neutrophil eosinophil coun... 129 | 129
Colorectal cancer 126 | 126
Alzheimer disease and age of o... 124 | 124
Multiple sclerosis 124 | 124
Cholesterol, total 123 | 123
Night sleep phenotypes 123 | 123
Lung cancer 122 | 122
Lymphocyte percentage of white... 122 | 122
Menarche (age at onset) 122 | 122
Neutrophil percentage of white... 121 | 121
Rheumatoid arthritis 121 | 121
Systolic blood pressure 120 | 120
Immature fraction of reticuloc... 118 | 118
Diisocyanate-induced asthma 116 | 116
HDL cholesterol 116 | 116
Allergic disease (asthma, hay ... 115 | 115
Educational attainment (years ... 114 | 114
Hematocrit 113 | 113
Hemoglobin concentration 112 | 112
LDL cholesterol 110 | 110
QT interval 110 | 110
Waist circumference adjusted f... 110 | 110
Mosquito bite size 107 | 107
Asthma 106 | 106
Lobe attachment (rater-scored ... 103 | 103
Peripheral arterial disease (t... 101 | 101
Pulse pressure 97 | 97
Bipolar disorder 94 | 94
Major depressive disorder 94 | 94
Prostate cancer 92 | 92
Parkinson's disease 90 | 90
Hip circumference adjusted for... 89 | 89
Metabolite levels 87 | 87
Triglycerides 87 | 87
Colonoscopy-negative controls ... 85 | 85
Mean corpuscular hemoglobin co... 85 | 85
Itch intensity from mosquito b... 84 | 84
Bipolar disorder and schizophr... 83 | 83
Resting heart rate 82 | 82
Macrophage inflammatory protei... 81 | 81
Migraine 81 | 81
Waist-to-hip ratio adjusted fo... 81 | 81
PR interval in Tripanosoma cru... 80 | 80
Cognitive performance 79 | 79
Glomerular filtration rate (cr... 78 | 78
Late-onset Alzheimer's disease 78 | 78
Waist circumference adjusted f... 75 | 75
Tuberculosis 73 | 73
Type 1 diabetes 73 | 73
Morning vs. evening chronotype 72 | 72

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Sulfotransferase 1C4 SULT1C4 Tbio Enzyme -1.19364 16.1 77
Trans-Golgi network integral membrane protein 2 TGOLN2 Tbio Non-IDG -2.09006 106.0 218
Tumor necrosis factor receptor superfamily member EDAR EDAR Tbio Non-IDG -2.21203 161.3 194
E3 SUMO-protein ligase RanBP2 RANBP2 Tbio Enzyme -2.24609 178.6 172