Development Level

Tbio 4 | 11,445

IMPC Phenotype

decreased vertical activity 2 | 208
enlarged heart 2 | 210
preweaning lethality, complete... 2 | 979
abnormal heart morphology 1 | 162
abnormal seminal vesicle morph... 1 | 114
embryonic lethality prior to o... 1 | 239
embryonic lethality prior to t... 1 | 278
preweaning lethality, incomple... 1 | 499

Disease

Carcinoma 3 | 11,493
lung cancer 3 | 4,740
ovarian cancer 3 | 8,520
Autosomal recessive hypohidrotic ectodermal dysplasia syndrome 2 | 3
Autosomal recessive predisposition 2 | 1,442
Ectodermal Dysplasia 10A, Hypohidrotic/Hair/Nail Type, Autosomal Dominant 2 | 3
Hypohidrotic ectodermal dysplasia 2 | 15
Kidney cancer 2 | 2,613
Multiple myeloma 2 | 1,332
atypical teratoid / rhabdoid tumor 2 | 5,112
interstitial cystitis 2 | 2,312
malignant mesothelioma 2 | 3,232
psoriasis 2 | 6,694
tuberculosis 2 | 2,010
Abnormality of nail of toe 1 | 11
Abnormality of the fingernails 1 | 51
Acute necrotizing encephalitis 1 | 2
Agammaglobulinemia 1 | 34
Alopecia 1 | 115
Anhidrosis 1 | 23
Anodontia 1 | 12
Autoimmune hemolytic anemia 1 | 31
Autoimmune lymphoproliferative syndrome 1 | 11
Autosomal dominant hypohidrotic ectodermal dysplasia syndrome (disorder) 1 | 3
Autosomal recessive hypohidrotic ectodermal dysplasia 1 | 3
Brain disease 1 | 96
Breast Neoplasms 1 | 445
Bronchiectasis 1 | 64
Christ-Siemens-Touraine syndrome 1 | 3
Chronic diarrhea 1 | 29
Chronic lung disease 1 | 6
Clouston syndrome 1 | 9
Colitis 1 | 54
Common variable immunodeficiency 1 | 101
Conjunctivitis 1 | 53
Conjunctivitis, recurrent 1 | 37
Decreased IgM 1 | 11
Decreased platelet count 1 | 111
Decreased size of teeth 1 | 62
Decreased width of tooth 1 | 59
Dental abnormalities 1 | 60
Developmental absence of tooth 1 | 7
Dry skin 1 | 75
Ectodermal Dysplasia 1 | 14
Ectodermal Dysplasia 3, Anhidrotic 1 | 2
Ectodermal Dysplasia, Hypohidrotic, Autosomal Recessive 1 | 3
Endometrial cancer 1 | 311
Everted lower lip vermilion 1 | 54
Extratemporal epilepsy 1 | 6
Fine hair 1 | 42
Frontal bossing 1 | 157
Fuhrmann syndrome 1 | 7
Functional diarrhea 1 | 4
Gastritis 1 | 47
Growth delay 1 | 114
Growth failure 1 | 114
Growth retardation 1 | 115
Hypodontia 1 | 81
Hypohidrosis 1 | 34
Hypothyroidism 1 | 122
Hypotrichosis 1 | 47
Immunoglobulin A deficiency (disorder) 1 | 19
Immunologic Deficiency Syndromes 1 | 113
Inflammatory myofibroblastic tumor 1 | 8
Influenza 1 | 142
Intolerant of heat 1 | 7
Kawasaki disease 1 | 28
Large intestine cancer 1 | 126
Lateral medullary syndrome 1 | 4
Lymphadenopathy 1 | 62
MICROPHTHALMIA, SYNDROMIC 14 1 | 2
Mammary Neoplasms 1 | 425
Microdontia (disorder) 1 | 59
Nail dysplasia 1 | 52
Periorbital hyperpigmentation 1 | 2
Periorbital wrinkles 1 | 2
Pneumonia 1 | 174
Poor growth 1 | 114
Precocious exfoliation of primary tooth 1 | 11
Progressive disorder 1 | 142
Protruding lower lip 1 | 54
Protruding upper lip 1 | 4
Reactive airway disease 1 | 21
Recurrent otitis media 1 | 42
Recurrent sinus disease 1 | 22
Recurrent sinusitis 1 | 22
Reye syndrome 1 | 11
Rubeosis iridis 1 | 4
Slow-growing hair 1 | 19
Sparse eyebrow 1 | 42
Sparse eyelashes 1 | 31
Thalassemia 1 | 53
Thick vermilion border 1 | 25
Thrombocytopenia 1 | 197
Tooth Abnormalities 1 | 69
Tooth agenesis 1 | 44
Tooth hypoplasia 1 | 7
Very poor growth 1 | 114
Xerosis 1 | 75
hereditary spastic paraplegia 1 | 318

Tissue

Blood and immune system 4 | 16,909
Cardiovascular System 4 | 15,192
Digestive Tract 4 | 17,369
Endocrine System 4 | 18,159
Female tissues 4 | 17,400
Liver and Pancreas 4 | 16,750
Male tissues 4 | 17,142
Nervous System 4 | 16,725
Respiratory system 4 | 16,393
Skin and soft tissues 4 | 17,230
Urinary Tract 4 | 16,678

Target Family

Non-IDG 3 | 12,091
Enzyme 1 | 4,145

GWAS Trait

Ear morphology 4 | 4
Obesity-related traits 569 | 569
Schizophrenia 533 | 533
Breast cancer 492 | 492
Body mass index 379 | 379
Height 369 | 369
Coronary artery disease 367 | 367
Blood protein levels 351 | 351
Post bronchodilator FEV1-FVC r... 308 | 308
Mean corpuscular volume 283 | 283
Platelet count 275 | 275
Intelligence (multi-trait anal... 267 | 267
Mean platelet volume 253 | 253
IgG glycosylation 250 | 250
Mean corpuscular hemoglobin 238 | 238
Inflammatory bowel disease 235 | 235
Plateletcrit 227 | 227
Crohn's disease 215 | 215
Type 2 diabetes 210 | 210
Red blood cell count 191 | 191
Monocyte count 183 | 183
Red cell distribution width 182 | 182
Eosinophil counts 180 | 180
Neuroticism 180 | 180
Platelet distribution width 174 | 174
Monocyte percentage of white c... 173 | 173
Post bronchodilator FEV1 173 | 173
Sum eosinophil basophil counts 173 | 173
White blood cell count 172 | 172
3-hydroxy-1-methylpropylmercap... 166 | 166
Eosinophil percentage of granu... 163 | 163
Eosinophil percentage of white... 163 | 163
Reticulocyte fraction of red c... 163 | 163
Ulcerative colitis 163 | 163
Granulocyte percentage of myel... 162 | 162
Itch intensity from mosquito b... 162 | 162
Systemic lupus erythematosus 159 | 159
High light scatter reticulocyt... 158 | 158
Lymphocyte counts 158 | 158
Reticulocyte count 158 | 158
Blood metabolite levels 157 | 157
Neutrophil count 154 | 154
High light scatter reticulocyt... 153 | 153
Neutrophil percentage of granu... 153 | 153
3-hydroxypropylmercapturic aci... 150 | 150
Tonsillectomy 149 | 149
Diastolic blood pressure 144 | 144
Sum basophil neutrophil counts 140 | 140
Autism spectrum disorder or sc... 134 | 134
Myeloid white cell count 133 | 133
Granulocyte count 132 | 132
Sum neutrophil eosinophil coun... 129 | 129
Colorectal cancer 126 | 126
Alzheimer disease and age of o... 124 | 124
Multiple sclerosis 124 | 124
Cholesterol, total 123 | 123
Night sleep phenotypes 123 | 123
Lung cancer 122 | 122
Lymphocyte percentage of white... 122 | 122
Menarche (age at onset) 122 | 122
Neutrophil percentage of white... 121 | 121
Rheumatoid arthritis 121 | 121
Systolic blood pressure 120 | 120
Immature fraction of reticuloc... 118 | 118
Diisocyanate-induced asthma 116 | 116
HDL cholesterol 116 | 116
Allergic disease (asthma, hay ... 115 | 115
Educational attainment (years ... 114 | 114
Hematocrit 113 | 113
Hemoglobin concentration 112 | 112
LDL cholesterol 110 | 110
QT interval 110 | 110
Waist circumference adjusted f... 110 | 110
Mosquito bite size 107 | 107
Asthma 106 | 106
Lobe attachment (rater-scored ... 103 | 103
Peripheral arterial disease (t... 101 | 101
Pulse pressure 97 | 97
Bipolar disorder 94 | 94
Major depressive disorder 94 | 94
Prostate cancer 92 | 92
Parkinson's disease 90 | 90
Hip circumference adjusted for... 89 | 89
Metabolite levels 87 | 87
Triglycerides 87 | 87
Colonoscopy-negative controls ... 85 | 85
Mean corpuscular hemoglobin co... 85 | 85
Itch intensity from mosquito b... 84 | 84
Bipolar disorder and schizophr... 83 | 83
Resting heart rate 82 | 82
Macrophage inflammatory protei... 81 | 81
Migraine 81 | 81
Waist-to-hip ratio adjusted fo... 81 | 81
PR interval in Tripanosoma cru... 80 | 80
Cognitive performance 79 | 79
Glomerular filtration rate (cr... 78 | 78
Late-onset Alzheimer's disease 78 | 78
Waist circumference adjusted f... 75 | 75
Tuberculosis 73 | 73
Type 1 diabetes 73 | 73
Morning vs. evening chronotype 72 | 72

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Lipopolysaccharide-responsive and beige-like anchor protein LRBA Tbio Non-IDG -2.99957 965.6 40
28S ribosomal protein S22, mitochondrial MRPS22 Tbio Non-IDG -2.42971 211.9 107
Tumor necrosis factor receptor superfamily member EDAR EDAR Tbio Non-IDG -2.21203 161.3 194
E3 SUMO-protein ligase RanBP2 RANBP2 Tbio Enzyme -2.24609 178.6 172