Development Level

Tbio 11 | 11,445
Tdark 2 | 6,588

IMPC Phenotype

preweaning lethality, incomple... 2 | 499
abnormal behavior 1 | 298
decreased KLRG1+ CD8 alpha bet... 1 | 2
decreased mean corpuscular hem... 1 | 50
embryonic lethality prior to t... 1 | 278
increased blood urea nitrogen ... 1 | 48
increased circulating sodium l... 1 | 71
prenatal lethality 1 | 28

Disease

Carcinoma 9 | 11,493
group 3 medulloblastoma 8 | 4,104
glioblastoma 7 | 5,792
adult high grade glioma 6 | 3,801
medulloblastoma, large-cell 6 | 6,241
atypical teratoid / rhabdoid tumor 5 | 5,112
ovarian cancer 5 | 8,520
primitive neuroectodermal tumor 5 | 3,035
psoriasis 5 | 6,694
Astrocytoma, Pilocytic 4 | 3,081
Breast cancer 4 | 3,578
Kidney cancer 4 | 2,613
ependymoma 4 | 4,679
invasive ductal carcinoma 4 | 2,951
osteosarcoma 4 | 7,950
Endometrial cancer 3 | 311
adrenocortical carcinoma 3 | 1,428
astrocytoma 3 | 1,146
intraductal papillary-mucinous neoplasm (IPMN) 3 | 3,291
oligodendroglioma 3 | 2,850
pancreatic cancer 3 | 2,398
pancreatic ductal adenocarcinoma liver metastasis 3 | 1,962
Autosomal recessive predisposition 2 | 1,442
Concave bridge of nose 2 | 195
Depressed nasal bridge 2 | 195
Depressed nasal root/bridge 2 | 195
Diastrophic dysplasia 2 | 21
Frontal bossing 2 | 157
Large intestine cancer 2 | 126
Liver cancer 2 | 604
Long philtrum 2 | 137
Rhizomelia 2 | 25
Schizophrenia 2 | 1,160
Short neck 2 | 140
Ventricular Septal Defects 2 | 119
atypical teratoid/rhabdoid tumor 2 | 357
cutaneous lupus erythematosus 2 | 1,057
dermatomyositis 2 | 966
gastric carcinoma 2 | 807
interstitial cystitis 2 | 2,312
intraductal papillary-mucinous adenoma (IPMA) 2 | 2,955
lung adenocarcinoma 2 | 2,716
lung carcinoma 2 | 2,843
non-small cell lung cancer 2 | 2,890
tuberculosis 2 | 2,010
Acquired flat foot 1 | 72
Acquired immunodeficiency syndrome 1 | 197
Acute conjunctivitis 1 | 4
Advanced bone age 1 | 35
Anterior/lateral radial head dislocation 1 | 1
Aortic Valve Insufficiency 1 | 40
Aortic root dilatation 1 | 11
Arthropathy 1 | 43
Bicuspid aortic valve 1 | 16
Bowed and upward slanting eyebrows 1 | 41
Bushy eyebrows 1 | 49
Congenital dyserythropoietic anemia 1 | 18
DOID:9917 1 | 31
Decreased size of teeth 1 | 62
Decreased width of tooth 1 | 59
Desbuquois dysplasia 1 | 13
Endometriosis of ovary 1 | 5
Esotropia 1 | 31
Flatfoot 1 | 73
Fundus dystrophy 1 | 83
Hypoplastic distal humeri 1 | 1
Idiopathic pulmonary arterial hypertension 1 | 40
Increased fibular diameter 1 | 4
Joint laxity 1 | 54
Knee joint valgus deformity 1 | 56
Kyphoscoliosis deformity of spine 1 | 60
Limited elbow flexion/extension 1 | 1
Limited knee flexion/extension 1 | 1
Metatarsus Varus 1 | 24
Microdontia (disorder) 1 | 59
Mitral Valve Prolapse Syndrome 1 | 39
Mitral regurgitation, mild 1 | 32
Mitral valve insufficiency 1 | 49
Mitral valve stenosis 1 | 14
Omodysplasia 1 1 | 1
Pendred Syndrome 1 | 22
Popliteal pterygium 1 | 4
Pre-Eclampsia 1 | 68
Pulmonary Stenosis 1 | 45
Pulmonary hypertension 1 | 85
Retinitis pigmentosa 25 1 | 9
Short distal phalanges 1 | 50
Short ulnae 1 | 24
Sickle Cell Anemia 1 | 53
Sparse eyebrow 1 | 42
Spatulate thumbs 1 | 3
Spondyloepiphyseal dysplasia with congenital joint dislocations 1 | 13
Thick, flared eyebrows 1 | 41
Toeing-in 1 | 24
ULNAR HYPOPLASIA 1 | 24
Ulnar bowing 1 | 10
Ventricular hypertrophy 1 | 6
Wide spaced nipples 1 | 46
Widely spaced teeth 1 | 31
cone-rod dystrophy 1 | 59

Tissue

Blood and immune system 11 | 16,909
Digestive Tract 11 | 17,369
Endocrine System 11 | 18,159
Female tissues 11 | 17,400
Liver and Pancreas 11 | 16,750
Male tissues 11 | 17,142
Nervous System 11 | 16,725
Respiratory system 11 | 16,393
Skin and soft tissues 11 | 17,230
Cardiovascular System 10 | 15,192
Urinary Tract 10 | 16,678

Target Family

Non-IDG 7 | 12,091
Enzyme 4 | 4,145
Kinase 1 | 634
Transporter 1 | 473

GWAS Trait

Disc degeneration (lumbar) 13 | 13
Obesity-related traits 569 | 569
Schizophrenia 533 | 533
Breast cancer 492 | 492
Body mass index 379 | 379
Height 369 | 369
Coronary artery disease 367 | 367
Blood protein levels 351 | 351
Post bronchodilator FEV1-FVC r... 308 | 308
Mean corpuscular volume 283 | 283
Platelet count 275 | 275
Intelligence (multi-trait anal... 267 | 267
Mean platelet volume 253 | 253
IgG glycosylation 250 | 250
Mean corpuscular hemoglobin 238 | 238
Inflammatory bowel disease 235 | 235
Plateletcrit 227 | 227
Crohn's disease 215 | 215
Type 2 diabetes 210 | 210
Red blood cell count 191 | 191
Monocyte count 183 | 183
Red cell distribution width 182 | 182
Eosinophil counts 180 | 180
Neuroticism 180 | 180
Platelet distribution width 174 | 174
Monocyte percentage of white c... 173 | 173
Post bronchodilator FEV1 173 | 173
Sum eosinophil basophil counts 173 | 173
White blood cell count 172 | 172
3-hydroxy-1-methylpropylmercap... 166 | 166
Eosinophil percentage of granu... 163 | 163
Eosinophil percentage of white... 163 | 163
Reticulocyte fraction of red c... 163 | 163
Ulcerative colitis 163 | 163
Granulocyte percentage of myel... 162 | 162
Itch intensity from mosquito b... 162 | 162
Systemic lupus erythematosus 159 | 159
High light scatter reticulocyt... 158 | 158
Lymphocyte counts 158 | 158
Reticulocyte count 158 | 158
Blood metabolite levels 157 | 157
Neutrophil count 154 | 154
High light scatter reticulocyt... 153 | 153
Neutrophil percentage of granu... 153 | 153
3-hydroxypropylmercapturic aci... 150 | 150
Tonsillectomy 149 | 149
Diastolic blood pressure 144 | 144
Sum basophil neutrophil counts 140 | 140
Autism spectrum disorder or sc... 134 | 134
Myeloid white cell count 133 | 133
Granulocyte count 132 | 132
Sum neutrophil eosinophil coun... 129 | 129
Colorectal cancer 126 | 126
Alzheimer disease and age of o... 124 | 124
Multiple sclerosis 124 | 124
Cholesterol, total 123 | 123
Night sleep phenotypes 123 | 123
Lung cancer 122 | 122
Lymphocyte percentage of white... 122 | 122
Menarche (age at onset) 122 | 122
Neutrophil percentage of white... 121 | 121
Rheumatoid arthritis 121 | 121
Systolic blood pressure 120 | 120
Immature fraction of reticuloc... 118 | 118
Diisocyanate-induced asthma 116 | 116
HDL cholesterol 116 | 116
Allergic disease (asthma, hay ... 115 | 115
Educational attainment (years ... 114 | 114
Hematocrit 113 | 113
Hemoglobin concentration 112 | 112
LDL cholesterol 110 | 110
QT interval 110 | 110
Waist circumference adjusted f... 110 | 110
Mosquito bite size 107 | 107
Asthma 106 | 106
Lobe attachment (rater-scored ... 103 | 103
Peripheral arterial disease (t... 101 | 101
Pulse pressure 97 | 97
Bipolar disorder 94 | 94
Major depressive disorder 94 | 94
Prostate cancer 92 | 92
Parkinson's disease 90 | 90
Hip circumference adjusted for... 89 | 89
Metabolite levels 87 | 87
Triglycerides 87 | 87
Colonoscopy-negative controls ... 85 | 85
Mean corpuscular hemoglobin co... 85 | 85
Itch intensity from mosquito b... 84 | 84
Bipolar disorder and schizophr... 83 | 83
Resting heart rate 82 | 82
Macrophage inflammatory protei... 81 | 81
Migraine 81 | 81
Waist-to-hip ratio adjusted fo... 81 | 81
PR interval in Tripanosoma cru... 80 | 80
Cognitive performance 79 | 79
Glomerular filtration rate (cr... 78 | 78
Late-onset Alzheimer's disease 78 | 78
Waist circumference adjusted f... 75 | 75
Tuberculosis 73 | 73
Type 1 diabetes 73 | 73
Morning vs. evening chronotype 72 | 72

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Ras-related protein Rab-40C RAB40C Tbio Non-IDG -0.89913 7.57 111
Putative protein phosphatase inhibitor 2-like protein 1 PPP1R2P1 Tdark Enzyme 0.00000 0
Glypican-6 GPC6 Tbio Non-IDG -1.33560 21.9 125
CUB and sushi domain-containing protein 1 CSMD1 Tbio Non-IDG -1.68684 47.7 0
ADP-ribosylation factor-like protein 8B ARL8B Tbio Enzyme -0.99083 12.0 99
Anion exchange transporter SLC26A7 Tbio Transporter -1.26445 19.4 41
Carbohydrate sulfotransferase 3 CHST3 Tbio Enzyme -2.32897 204.3 128
Myosin-14 MYH14 Tbio Non-IDG -1.41429 24.4 155
Testican-2 SPOCK2 Tbio Non-IDG -0.87419 6.75 57
Protein eyes shut homolog EYS Tbio Non-IDG -2.09079 119.9 24