Development Level

Tbio 80 | 11,445
Tdark 22 | 6,588
Tchem 9 | 1,598
Tclin 5 | 613

Collection

GPCR: IDG Consortium (Targets) 1 | 126
Ion Channel: IDG Consortium (T... 1 | 99

IMPC Phenotype

preweaning lethality, incomple... 6 | 499
abnormal behavior 5 | 298
decreased total body fat amoun... 3 | 207
hypoactivity 3 | 132
decreased body weight 2 | 161
decreased circulating HDL chol... 2 | 68
decreased circulating glucose ... 2 | 126
decreased prepulse inhibition 2 | 82
decreased startle reflex 2 | 75
hyperactivity 2 | 148
improved glucose tolerance 2 | 79
increased bone mineral content 2 | 108
increased circulating triglyce... 2 | 42
increased lean body mass 2 | 172
increased or absent threshold ... 2 | 101
increased spleen weight 2 | 10
preweaning lethality, complete... 2 | 979
short tibia 2 | 97
abnormal bone structure 1 | 187
abnormal colon morphology 1 | 3
abnormal duodenum morphology 1 | 4
abnormal embryo size 1 | 220
abnormal eye anterior chamber ... 1 | 9
abnormal eye morphology 1 | 68
abnormal heart left ventricle ... 1 | 16
abnormal locomotor behavior 1 | 24
abnormal nail morphology 1 | 8
abnormal retina morphology 1 | 71
abnormal seminal vesicle morph... 1 | 114
abnormal sleep behavior 1 | 70
abnormal spleen morphology 1 | 55
abnormal tail movements 1 | 12
abnormal vertebrae morphology 1 | 18
absent prostate gland 1 | 1
absent seminal vesicle 1 | 4
absent startle reflex 1 | 24
absent testes 1 | 6
cardiovascular system phenotyp... 1 | 36
corneal opacity 1 | 32
decreased KLRG1+ CD8 alpha bet... 1 | 2
decreased basophil cell number 1 | 16
decreased body length 1 | 101
decreased circulating bilirubi... 1 | 19
decreased circulating calcium ... 1 | 36
decreased circulating chloride... 1 | 30
decreased circulating free fat... 1 | 31
decreased circulating fructosa... 1 | 30
decreased circulating insulin ... 1 | 76
decreased circulating iron lev... 1 | 32
decreased circulating lipase l... 1 | 3
decreased circulating serum al... 1 | 82
decreased eosinophil cell numb... 1 | 24
decreased erythrocyte cell num... 1 | 62
decreased grip strength 1 | 116
decreased heart weight 1 | 27
decreased hemoglobin content 1 | 68
decreased vertical activity 1 | 208
enlarged lymph nodes 1 | 37
female infertility 1 | 60
impaired glucose tolerance 1 | 75
increased bone mineral density 1 | 72
increased circulating alkaline... 1 | 122
increased circulating fructosa... 1 | 13
increased circulating phosphat... 1 | 26
increased circulating serum al... 1 | 22
increased circulating sodium l... 1 | 71
increased exploration in new e... 1 | 8
increased fasted circulating g... 1 | 76
increased heart rate 1 | 23
increased mean corpuscular hem... 1 | 96
increased mean corpuscular vol... 1 | 92
increased red blood cell distr... 1 | 34
increased respiratory quotient 1 | 2
long tibia 1 | 25
male infertility 1 | 123
persistence of hyaloid vascula... 1 | 33
prolonged QT interval 1 | 38
prolonged ST segment 1 | 36
small testis 1 | 58
thrombocytosis 1 | 27

Disease

Carcinoma 86 | 11,493
ovarian cancer 66 | 8,520
glioblastoma 53 | 5,792
medulloblastoma, large-cell 53 | 6,241
osteosarcoma 51 | 7,950
ependymoma 48 | 4,679
adult high grade glioma 46 | 3,801
atypical teratoid / rhabdoid tumor 46 | 5,112
Breast cancer 44 | 3,578
psoriasis 42 | 6,694
group 3 medulloblastoma 37 | 4,104
Kidney cancer 35 | 2,613
invasive ductal carcinoma 33 | 2,951
primitive neuroectodermal tumor 33 | 3,035
lung carcinoma 32 | 2,843
Astrocytoma, Pilocytic 31 | 3,081
lung cancer 31 | 4,740
pancreatic cancer 31 | 2,398
malignant mesothelioma 30 | 3,232
pituitary cancer 30 | 1,972
oligodendroglioma 26 | 2,850
astrocytic glioma 25 | 2,597
intraductal papillary-mucinous adenoma (IPMA) 25 | 2,955
lung adenocarcinoma 25 | 2,716
non-small cell lung cancer 24 | 2,890
subependymal giant cell astrocytoma 24 | 2,287
interstitial cystitis 23 | 2,312
intraductal papillary-mucinous carcinoma (IPMC) 23 | 2,989
ductal carcinoma in situ 20 | 1,745
Cancer 19 | 2,499
cystic fibrosis 19 | 1,696
group 4 medulloblastoma 19 | 1,855
intraductal papillary-mucinous neoplasm (IPMN) 19 | 3,291
pancreatic ductal adenocarcinoma liver metastasis 19 | 1,962
ulcerative colitis 19 | 1,819
colon cancer 18 | 1,478
Pick disease 17 | 1,894
adrenocortical carcinoma 17 | 1,428
tuberculosis 16 | 2,010
Rheumatoid arthritis 15 | 1,191
breast carcinoma 15 | 1,638
Autosomal recessive predisposition 14 | 1,442
Liver cancer 13 | 604
Schizophrenia 13 | 1,160
Atopic dermatitis 12 | 952
cutaneous lupus erythematosus 12 | 1,057
gastric carcinoma 12 | 807
Type 2 diabetes mellitus 11 | 272
acute quadriplegic myopathy 11 | 1,158
non primary Sjogren syndrome sicca 11 | 891
primary pancreatic ductal adenocarcinoma 11 | 1,109
Intellectual disability 10 | 1,016
dermatomyositis 10 | 966
Parkinson's disease 9 | 392
active Crohn's disease 9 | 922
astrocytoma 9 | 1,146
nasopharyngeal carcinoma 9 | 1,058
Duchenne muscular dystrophy 8 | 601
Epilepsy 8 | 792
Liver Cirrhosis, Experimental 8 | 769
diabetes mellitus 8 | 1,728
fibroadenoma 8 | 559
spina bifida 8 | 1,074
Acquired metabolic disease 7 | 336
Endometrial cancer 7 | 311
Infantile onset 7 | 238
Melanoma 7 | 711
Short stature 7 | 531
Skin cancer 7 | 469
active ulcerative colitis 7 | 764
acute myeloid leukemia 7 | 783
autosomal dominant Emery-Dreifuss muscular dystrophy 7 | 510
juvenile dermatomyositis 7 | 1,187
medulloblastoma 7 | 720
Attention deficit hyperactivity disorder 6 | 278
Dull intelligence 6 | 645
Endometriosis 6 | 540
Highly variable severity 6 | 157
Low intelligence 6 | 645
Mental Retardation 6 | 645
Mental deficiency 6 | 645
Motor delay 6 | 147
Multiple Sclerosis 6 | 540
Multiple myeloma 6 | 1,332
Muscle hypotonia 6 | 571
Neoplasm Invasiveness 6 | 161
No development of motor milestones 6 | 147
Poor school performance 6 | 645
Prostatic Neoplasms 6 | 495
Splenomegaly 6 | 190
Variable expressivity 6 | 157
aldosterone-producing adenoma 6 | 665
esophageal adenocarcinoma 6 | 737
periodontitis 6 | 293
primary Sjogren syndrome 6 | 735
progressive supranuclear palsy 6 | 676
Cognitive delay 5 | 608
Global developmental delay 5 | 608
Mental and motor retardation 5 | 608
Small head 5 | 374

Tissue

Endocrine System 109 | 18,159
Female tissues 107 | 17,400
Nervous System 107 | 16,725
Digestive Tract 106 | 17,369
Male tissues 106 | 17,142
Respiratory system 106 | 16,393
Blood and immune system 104 | 16,909
Liver and Pancreas 103 | 16,750
Urinary Tract 103 | 16,678
Skin and soft tissues 102 | 17,230
Cardiovascular System 97 | 15,192

Target Family

Non-IDG 64 | 12,091
Enzyme 24 | 4,145
Transcription Factor 10 | 1,400
Transporter 5 | 473
Kinase 4 | 634
Ion Channel 3 | 344
GPCR 2 | 408
oGPCR 2 | 421
Epigenetic 1 | 242
Nuclear Receptor 1 | 48

GWAS Trait

Diisocyanate-induced asthma 116 | 116
Obesity-related traits 569 | 569
Schizophrenia 533 | 533
Breast cancer 492 | 492
Body mass index 379 | 379
Height 369 | 369
Coronary artery disease 367 | 367
Blood protein levels 351 | 351
Post bronchodilator FEV1-FVC r... 308 | 308
Mean corpuscular volume 283 | 283
Platelet count 275 | 275
Intelligence (multi-trait anal... 267 | 267
Mean platelet volume 253 | 253
IgG glycosylation 250 | 250
Mean corpuscular hemoglobin 238 | 238
Inflammatory bowel disease 235 | 235
Plateletcrit 227 | 227
Crohn's disease 215 | 215
Type 2 diabetes 210 | 210
Red blood cell count 191 | 191
Monocyte count 183 | 183
Red cell distribution width 182 | 182
Eosinophil counts 180 | 180
Neuroticism 180 | 180
Platelet distribution width 174 | 174
Monocyte percentage of white c... 173 | 173
Post bronchodilator FEV1 173 | 173
Sum eosinophil basophil counts 173 | 173
White blood cell count 172 | 172
3-hydroxy-1-methylpropylmercap... 166 | 166
Eosinophil percentage of granu... 163 | 163
Eosinophil percentage of white... 163 | 163
Reticulocyte fraction of red c... 163 | 163
Ulcerative colitis 163 | 163
Granulocyte percentage of myel... 162 | 162
Itch intensity from mosquito b... 162 | 162
Systemic lupus erythematosus 159 | 159
High light scatter reticulocyt... 158 | 158
Lymphocyte counts 158 | 158
Reticulocyte count 158 | 158
Blood metabolite levels 157 | 157
Neutrophil count 154 | 154
High light scatter reticulocyt... 153 | 153
Neutrophil percentage of granu... 153 | 153
3-hydroxypropylmercapturic aci... 150 | 150
Tonsillectomy 149 | 149
Diastolic blood pressure 144 | 144
Sum basophil neutrophil counts 140 | 140
Autism spectrum disorder or sc... 134 | 134
Myeloid white cell count 133 | 133
Granulocyte count 132 | 132
Sum neutrophil eosinophil coun... 129 | 129
Colorectal cancer 126 | 126
Alzheimer disease and age of o... 124 | 124
Multiple sclerosis 124 | 124
Cholesterol, total 123 | 123
Night sleep phenotypes 123 | 123
Lung cancer 122 | 122
Lymphocyte percentage of white... 122 | 122
Menarche (age at onset) 122 | 122
Neutrophil percentage of white... 121 | 121
Rheumatoid arthritis 121 | 121
Systolic blood pressure 120 | 120
Immature fraction of reticuloc... 118 | 118
HDL cholesterol 116 | 116
Allergic disease (asthma, hay ... 115 | 115
Educational attainment (years ... 114 | 114
Hematocrit 113 | 113
Hemoglobin concentration 112 | 112
LDL cholesterol 110 | 110
QT interval 110 | 110
Waist circumference adjusted f... 110 | 110
Mosquito bite size 107 | 107
Asthma 106 | 106
Lobe attachment (rater-scored ... 103 | 103
Peripheral arterial disease (t... 101 | 101
Pulse pressure 97 | 97
Bipolar disorder 94 | 94
Major depressive disorder 94 | 94
Prostate cancer 92 | 92
Parkinson's disease 90 | 90
Hip circumference adjusted for... 89 | 89
Metabolite levels 87 | 87
Triglycerides 87 | 87
Colonoscopy-negative controls ... 85 | 85
Mean corpuscular hemoglobin co... 85 | 85
Itch intensity from mosquito b... 84 | 84
Bipolar disorder and schizophr... 83 | 83
Resting heart rate 82 | 82
Macrophage inflammatory protei... 81 | 81
Migraine 81 | 81
Waist-to-hip ratio adjusted fo... 81 | 81
PR interval in Tripanosoma cru... 80 | 80
Cognitive performance 79 | 79
Glomerular filtration rate (cr... 78 | 78
Late-onset Alzheimer's disease 78 | 78
Waist circumference adjusted f... 75 | 75
Tuberculosis 73 | 73
Type 1 diabetes 73 | 73
Morning vs. evening chronotype 72 | 72

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Thrombopoietin THPO Tbio Non-IDG -3.23551 1632.3 440
Zinc transporter 1 SLC30A1 Tbio Transporter -2.12639 135.9 148
Cytoplasmic phosphatidylinositol transfer protein 1 PITPNC1 Tbio Non-IDG -0.74280 6.46 51
CUB and sushi domain-containing protein 1 CSMD1 Tbio Non-IDG -1.68684 47.7 0
EF-hand domain-containing protein D1 EFHD1 Tbio Non-IDG -1.96673 92.2 187
Arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 1 ASAP1 Tbio Non-IDG -1.76454 62.6 183
Collagen alpha-1(XII) chain COL12A1 Tbio Non-IDG -1.36571 21.4 38
BMP-binding endothelial regulator protein BMPER Tbio Non-IDG -2.51174 317.7 120
Krueppel-like factor 13 KLF13 Tbio Transcription Factor -1.40009 27.3 111
Coiled-coil domain-containing protein 178 CCDC178 Tdark Non-IDG 0.27 0.79 13