Development Level

Tbio 44 | 10,625
Tdark 16 | 7,003
Tchem 9 | 1,890
Tclin 3 | 602

Collection

Eligible Ion Channel Proteins 1 | 117

IMPC Term

abnormal behavior 4 | 226
preweaning lethality, incomple... 3 | 260
abnormal heart left ventricle ... 2 | 20
decreased caudal vertebrae num... 2 | 49
decreased circulating glucose ... 2 | 121
decreased prepulse inhibition 2 | 52
decreased startle reflex 2 | 48
increased or absent threshold ... 2 | 128
abnormal locomotor activation 1 | 26
abnormal retina morphology 1 | 100
absent startle reflex 1 | 15
cardiovascular system phenotyp... 1 | 35
decreased KLRG1-positive NK ce... 1 | 9
decreased Ly6C low monocyte nu... 1 | 23
decreased body length 1 | 108
decreased body weight 1 | 174
decreased bone mineral density 1 | 126
decreased circulating HDL chol... 1 | 77
decreased circulating calcium ... 1 | 33
decreased circulating chloride... 1 | 32
decreased circulating choleste... 1 | 85
decreased circulating free fat... 1 | 39
decreased circulating fructosa... 1 | 31
decreased circulating insulin ... 1 | 75
decreased circulating serum al... 1 | 79
decreased heart weight 1 | 44
decreased lean body mass 1 | 195
decreased lumbar vertebrae num... 1 | 62
decreased mean corpuscular vol... 1 | 50
decreased rib number 1 | 59
decreased thoracic vertebrae n... 1 | 7
decreased total body fat amoun... 1 | 186
hyperactivity 1 | 108
hypoactivity 1 | 89
improved glucose tolerance 1 | 56
increased Ly6C high monocyte n... 1 | 12
increased circulating alkaline... 1 | 119
increased circulating free fat... 1 | 17
increased circulating fructosa... 1 | 11
increased circulating sodium l... 1 | 71
increased circulating triglyce... 1 | 24
increased mean corpuscular vol... 1 | 91
increased neutrophil cell numb... 1 | 15
increased red blood cell distr... 1 | 21
persistence of hyaloid vascula... 1 | 22
preweaning lethality, complete... 1 | 633
short tibia 1 | 82
straub tail 1 | 26

Disease

ovarian cancer 40 | 8,484
medulloblastoma, large-cell 35 | 6,234
glioblastoma 33 | 5,572
osteosarcoma 33 | 7,933
psoriasis 25 | 6,685
Carcinoma 23 | 2,147
atypical teratoid / rhabdoid tumor 23 | 4,369
primitive neuroectodermal tumor 20 | 3,031
lung cancer 19 | 4,466
lung carcinoma 19 | 2,844
pituitary cancer 19 | 1,972
Breast cancer 18 | 3,094
interstitial cystitis 18 | 2,299
pilocytic astrocytoma 18 | 3,086
intraductal papillary-mucinous adenoma (IPMA) 17 | 2,956
adult high grade glioma 16 | 2,148
lung adenocarcinoma 16 | 2,713
malignant mesothelioma 16 | 3,162
subependymal giant cell astrocytoma 15 | 2,287
astrocytic glioma 14 | 2,241
invasive ductal carcinoma 14 | 2,950
oligodendroglioma 14 | 2,849
pediatric high grade glioma 14 | 2,712
ependymoma 13 | 2,514
intraductal papillary-mucinous carcinoma (IPMC) 13 | 2,988
medulloblastoma 13 | 1,524
non-small cell lung cancer 13 | 2,798
pancreatic cancer 12 | 2,300
posterior fossa group B ependymoma 12 | 1,530
group 4 medulloblastoma 11 | 1,875
intraductal papillary-mucinous neoplasm (IPMN) 11 | 3,289
Cancer 10 | 2,346
Pick disease 10 | 1,893
cystic fibrosis 10 | 1,665
ductal carcinoma in situ 10 | 1,745
ulcerative colitis 10 | 2,087
adrenocortical carcinoma 9 | 1,427
colon cancer 9 | 1,475
posterior fossa group A ependymoma 9 | 1,511
Schizophrenia 8 | 501
cutaneous lupus erythematosus 8 | 1,056
Obesity 7 | 616
Rheumatoid Arthritis 7 | 1,160
group 3 medulloblastoma 7 | 2,254
Atopic dermatitis 6 | 944
atypical teratoid/rhabdoid tumor 6 | 1,095
breast carcinoma 6 | 1,614
non primary Sjogren syndrome sicca 6 | 840
primary pancreatic ductal adenocarcinoma 6 | 1,271
tuberculosis 6 | 1,557
Intellectual disability 5 | 573
active Crohn's disease 5 | 918
astrocytoma 5 | 1,493
dermatomyositis 5 | 933
gastric carcinoma 5 | 832
nasopharyngeal carcinoma 5 | 1,056
non-small cell lung carcinoma 5 | 413
pancreatic ductal adenocarcinoma liver metastasis 5 | 1,795
primary Sjogren syndrome 5 | 789
sonic hedgehog group medulloblastoma 5 | 1,482
Alzheimer's disease 4 | 644
Parkinson's disease 4 | 364
Prostatic Neoplasms 4 | 471
Substance-Related Disorders 4 | 114
Type 2 diabetes mellitus 4 | 189
Waldenstrons macroglobulinemia 4 | 765
acute myeloid leukemia 4 | 780
chronic rhinosinusitis 4 | 512
diabetes mellitus 4 | 1,663
fibroadenoma 4 | 557
hepatocellular carcinoma 4 | 532
progressive supranuclear palsy 4 | 674
spina bifida 4 | 1,064
Acquired metabolic disease 3 | 267
Asphyxiating thoracic dystrophy 3 | 32
Asthma, Occupational 3 | 3
Chronic obstructive pulmonary disease 3 | 146
Endometriosis 3 | 535
Epilepsy 3 | 346
Kidney cancer 3 | 118
Liver disease 3 | 219
Liver neoplasms 3 | 109
Osteoporosis 3 | 257
Renal Cell Carcinoma 3 | 199
Sensenbrenner syndrome 3 | 15
esophageal adenocarcinoma 3 | 737
gastric cancer 3 | 430
juvenile dermatomyositis 3 | 1,189
nephrosclerosis 3 | 329
ovarian neoplasm 3 | 97
severe Alzheimer's disease 3 | 49
Diabetes Mellitus, Non-Insulin-Dependent 2 | 157
Hypertensive disease 2 | 193
Multiple Sclerosis 2 | 498
Peripheral Neuropathy 2 | 303
acute quadriplegic myopathy 2 | 1,157
autosomal dominant Emery-Dreifuss muscular dystrophy 2 | 499
hearing impairment 2 | 40
pancreatic carcinoma 2 | 567
urothelial carcinoma 2 | 318

Tissue

Digestive Tract 70 | 18,473
Endocrine System 70 | 18,512
Female tissues 70 | 18,647
Nervous System 70 | 18,561
Urinary Tract 70 | 18,444
Blood and immune system 69 | 17,995
Cardiovascular System 69 | 17,958
Liver and Pancreas 69 | 18,136
Male tissues 68 | 17,969
Respiratory system 68 | 17,484
Skin and soft tissues 68 | 18,115

Target Family

Non-IDG 45 | 11,971
Enzyme 12 | 4,146
Transcription Factor 5 | 1,400
Kinase 3 | 634
Transporter 3 | 473
Ion Channel 2 | 341
Epigenetic 1 | 242
oGPCR 1 | 421

GWAS Trait

Diisocyanate-induced asthma 72 | 72
Obesity-related traits 380 | 380
Schizophrenia 334 | 334
Height 250 | 250
Post bronchodilator FEV1/FVC r... 192 | 192
Body mass index 180 | 180
IgG glycosylation 162 | 162
Inflammatory bowel disease 117 | 117
Post bronchodilator FEV1 112 | 112
Crohn's disease 110 | 110
Blood metabolite levels 103 | 103
Type 2 diabetes 94 | 94
3-hydroxy-1-methylpropylmercap... 93 | 93
3-hydroxypropylmercapturic aci... 92 | 92
Ulcerative colitis 89 | 89
Platelet count 79 | 79
Systemic lupus erythematosus 78 | 78
HDL cholesterol 76 | 76
Rheumatoid arthritis 74 | 74
Cholesterol, total 73 | 73
Menarche (age at onset) 73 | 73
Multiple sclerosis 68 | 68
LDL cholesterol 67 | 67
QT interval 58 | 58
Metabolite levels 55 | 55
Atopic dermatitis 54 | 54
Bipolar disorder and schizophr... 54 | 54
Breast cancer 54 | 54
Prostate cancer 54 | 54
Triglycerides 53 | 53
Bipolar disorder 52 | 52
HIV-1 control 50 | 50
Post bronchodilator FEV1/FVC r... 50 | 50
HIV-1 viral setpoint 49 | 49
Cognitive performance 48 | 48
Amyotrophic lateral sclerosis ... 46 | 46
Bone mineral density 46 | 46
Clozapine-induced agranulocyto... 46 | 46
Attention deficit hyperactivit... 44 | 44
Blood pressure 44 | 44
Coronary heart disease 43 | 43
Glomerular filtration rate (cr... 43 | 43
Parkinson's disease 43 | 43
Type 1 diabetes 42 | 42
PR interval in Tripanosoma cru... 40 | 40
Post bronchodilator FEV1 in CO... 39 | 39
Alzheimer's disease (cognitive... 38 | 38
Educational attainment 38 | 38
Pulmonary function 38 | 38
Diffuse large B cell lymphoma 37 | 37
Inflammatory skin disease 37 | 37
Beta-2 microglubulin plasma le... 36 | 36
Glucose homeostasis traits 36 | 36
Urate levels 36 | 36
Blood metabolite ratios 35 | 35
Psoriasis 35 | 35
Autism spectrum disorder, atte... 34 | 34
Migraine 33 | 33
Coronary artery disease 32 | 32
Metabolic traits 32 | 32
Waist-to-hip ratio adjusted fo... 32 | 32
Cognitive function 31 | 31
Colorectal cancer 31 | 31
Amyotrophic lateral sclerosis 30 | 30
Myopia (pathological) 30 | 30
Obesity 30 | 30
Response to amphetamines 30 | 30
Systolic blood pressure 30 | 30
Alzheimer's disease (late onse... 29 | 29
Celiac disease 29 | 29
Phospholipid levels (plasma) 29 | 29
Red blood cell traits 29 | 29
Advanced age-related macular d... 28 | 28
Dental caries 28 | 28
Fibrinogen levels 28 | 28
Parental extreme longevity (95... 28 | 28
Pulmonary function (interactio... 28 | 28
Asthma 27 | 27
Cognitive decline rate in late... 27 | 27
Glomerular filtration rate in ... 27 | 27
Longevity 27 | 27
Mean platelet volume 27 | 27
Chronic kidney disease 26 | 26
Diabetic kidney disease 26 | 26
Diastolic blood pressure 26 | 26
Coronary artery calcification 25 | 25
Metabolic syndrome 25 | 25
Pancreatic cancer 25 | 25
Protein quantitative trait loc... 25 | 25
Hypertension 24 | 24
Migraine - clinic-based 24 | 24
Parental longevity (combined p... 24 | 24
Primary biliary cirrhosis 24 | 24
Thiazide-induced adverse metab... 24 | 24
Menopause (age at onset) 23 | 23
Response to antipsychotic trea... 23 | 23
Age-related macular degenerati... 22 | 22
Immune response to smallpox va... 22 | 22
Mild influenza (H1N1) infectio... 22 | 22
Sudden cardiac arrest 22 | 22

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Equilibrative nucleoside transporter 3 SLC29A3 Tbio Transporter -2.36515 247.3 58
Transmembrane protein 132D TMEM132D Tbio Non-IDG -2.20806 159.4 59
Calsyntenin-1 CLSTN1 Tbio Non-IDG -1.08669 14.3 106
Polypeptide N-acetylgalactosaminyltransferase 18 GALNT18 Tdark Enzyme -0.28065 3.03 33
Zinc finger protein GLI2 GLI2 Tchem Transcription Factor -2.51321 325.2 174
Formiminotransferase N-terminal subdomain-containing protein FTCDNL1 Tdark Enzyme 0.00000 1.00 0
Putative protein KRIP1 KLKP1 Tdark Non-IDG 0.00000 0
Cytoplasmic dynein 2 heavy chain 1 DYNC2H1 Tbio Non-IDG -1.59494 38.2 10
Interleukin-2 receptor subunit alpha IL2RA Tclin Non-IDG -2.98987 913.0 1297
PDZ domain-containing RING finger protein 4 PDZRN4 Tdark Non-IDG -0.30752 2.34 30