Development Level

Tbio 92 | 11,445
Tdark 22 | 6,588
Tchem 20 | 1,598
Tclin 10 | 613

Collection

Ion Channel: IDG Consortium (T... 2 | 99
Kinase: IDG Consortium (Target... 2 | 125
GPCR: IDG Consortium (Targets) 1 | 126
Kinase: IDG Consortium (Comple... 1 | 37

IMPC Phenotype

preweaning lethality, complete... 9 | 979
enlarged heart 6 | 210
abnormal behavior 4 | 298
abnormal seminal vesicle morph... 4 | 114
decreased body weight 4 | 161
decreased prepulse inhibition 4 | 82
increased lean body mass 4 | 172
abnormal embryo size 3 | 220
abnormal heart morphology 3 | 162
decreased circulating glucose ... 3 | 126
embryonic growth retardation 3 | 106
embryonic lethality prior to t... 3 | 278
enlarged lymph nodes 3 | 37
increased circulating amylase ... 3 | 25
increased startle reflex 3 | 112
increased total body fat amoun... 3 | 134
preweaning lethality, incomple... 3 | 499
abnormal bone mineralization 2 | 38
abnormal bone structure 2 | 187
abnormal gait 2 | 69
abnormal locomotor activation 2 | 16
abnormal startle reflex 2 | 15
cataract 2 | 92
corneal opacity 2 | 32
decreased blood urea nitrogen ... 2 | 51
decreased bone mineral density 2 | 126
decreased circulating LDL chol... 2 | 38
decreased circulating calcium ... 2 | 36
decreased circulating insulin ... 2 | 76
decreased circulating iron lev... 2 | 32
decreased circulating total pr... 2 | 49
decreased erythrocyte cell num... 2 | 62
decreased fasted circulating g... 2 | 65
decreased hematocrit 2 | 46
decreased hemoglobin content 2 | 68
decreased total body fat amoun... 2 | 207
decreased vertical activity 2 | 208
hypoactivity 2 | 132
improved glucose tolerance 2 | 79
increased blood urea nitrogen ... 2 | 48
increased circulating fructosa... 2 | 13
limb grasping 2 | 41
prenatal lethality prior to he... 2 | 87
prolonged ST segment 2 | 36
tremors 2 | 39
abnormal coat-hair pigmentatio... 1 | 64
abnormal cornea morphology 1 | 31
abnormal cranium morphology 1 | 36
abnormal epididymis morphology 1 | 42
abnormal head size 1 | 6
abnormal iris morphology 1 | 13
abnormal lens morphology 1 | 81
abnormal response to new envir... 1 | 10
abnormal retinal blood vessel ... 1 | 26
abnormal sleep behavior 1 | 70
abnormal snout morphology 1 | 23
abnormal spleen morphology 1 | 55
abnormal vibrissa morphology 1 | 25
absent pinna reflex 1 | 23
absent vibrissae 1 | 12
decreased bone mineral content 1 | 151
decreased circulating choleste... 1 | 93
decreased circulating phosphat... 1 | 27
decreased circulating serum al... 1 | 82
decreased circulating triglyce... 1 | 79
decreased exploration in new e... 1 | 11
decreased grip strength 1 | 116
decreased lactate dehydrogenas... 1 | 16
decreased lean body mass 1 | 135
decreased spleen weight 1 | 10
decreased startle reflex 1 | 75
edema 1 | 59
embryonic lethality prior to o... 1 | 239
enlarged epididymis 1 | 31
enlarged spleen 1 | 41
female infertility 1 | 60
impaired glucose tolerance 1 | 75
increased body length 1 | 32
increased body weight 1 | 25
increased bone mineral content 1 | 108
increased circulating HDL chol... 1 | 80
increased circulating alkaline... 1 | 122
increased circulating choleste... 1 | 66
increased circulating glucose ... 1 | 24
increased circulating iron lev... 1 | 30
increased circulating magnesiu... 1 | 10
increased circulating sodium l... 1 | 71
increased circulating triglyce... 1 | 42
increased heart weight 1 | 62
increased hematocrit 1 | 46
increased hemoglobin content 1 | 45
increased mean platelet volume 1 | 45
increased monocyte cell number 1 | 63
increased vertical activity 1 | 24
male infertility 1 | 123
short tibia 1 | 97
shortened ST segment 1 | 10
small kidney 1 | 16
small testis 1 | 58
thrombocytosis 1 | 27

Disease

Carcinoma 108 | 11,493
osteosarcoma 78 | 7,950
ovarian cancer 75 | 8,520
medulloblastoma, large-cell 66 | 6,241
atypical teratoid / rhabdoid tumor 55 | 5,112
glioblastoma 55 | 5,792
psoriasis 53 | 6,694
ependymoma 50 | 4,679
adult high grade glioma 46 | 3,801
lung cancer 44 | 4,740
Kidney cancer 43 | 2,613
Astrocytoma, Pilocytic 40 | 3,081
group 3 medulloblastoma 40 | 4,104
intraductal papillary-mucinous adenoma (IPMA) 36 | 2,955
lung carcinoma 36 | 2,843
Breast cancer 35 | 3,578
intraductal papillary-mucinous carcinoma (IPMC) 35 | 2,989
lung adenocarcinoma 34 | 2,716
malignant mesothelioma 34 | 3,232
primitive neuroectodermal tumor 33 | 3,035
intraductal papillary-mucinous neoplasm (IPMN) 31 | 3,291
astrocytic glioma 30 | 2,597
interstitial cystitis 30 | 2,312
invasive ductal carcinoma 30 | 2,951
non-small cell lung cancer 30 | 2,890
oligodendroglioma 29 | 2,850
subependymal giant cell astrocytoma 29 | 2,287
Cancer 28 | 2,499
Essential Hypertension 28 | 94
tuberculosis 28 | 2,010
pancreatic cancer 27 | 2,398
pituitary cancer 24 | 1,972
Schizophrenia 23 | 1,160
cystic fibrosis 23 | 1,696
Autosomal recessive predisposition 22 | 1,442
Pick disease 22 | 1,894
ductal carcinoma in situ 21 | 1,745
ulcerative colitis 21 | 1,819
Bipolar Disorder 18 | 666
Melanoma 18 | 711
diabetes mellitus 17 | 1,728
Hypertension 16 | 396
Obesity 16 | 678
group 4 medulloblastoma 16 | 1,855
gastric carcinoma 15 | 807
breast carcinoma 14 | 1,638
primary pancreatic ductal adenocarcinoma 14 | 1,109
Liver cancer 13 | 604
adrenocortical carcinoma 13 | 1,428
colon cancer 13 | 1,478
juvenile dermatomyositis 13 | 1,187
Alzheimer's disease 12 | 658
Depressive disorder 12 | 409
active Crohn's disease 12 | 922
astrocytoma 12 | 1,146
Acquired metabolic disease 11 | 336
Coronary artery disease 11 | 268
Osteoporosis 11 | 363
Rheumatoid arthritis 11 | 1,191
Seizures 11 | 596
Skin cancer 11 | 469
spina bifida 11 | 1,074
Epilepsy 10 | 792
Intellectual disability 10 | 1,016
Parkinson's disease 10 | 392
autosomal dominant Emery-Dreifuss muscular dystrophy 10 | 510
medulloblastoma 10 | 720
nasopharyngeal carcinoma 10 | 1,058
primary Sjogren syndrome 10 | 735
Atrial Fibrillation 9 | 124
Breast Neoplasms 9 | 445
Cognitive delay 9 | 608
Duchenne muscular dystrophy 9 | 601
Global developmental delay 9 | 608
Hypertensive disease 9 | 292
Kidney disease 9 | 430
Mammary Neoplasms 9 | 425
Mental Depression 9 | 333
Mental and motor retardation 9 | 608
Neuropathy 9 | 261
Peripheral vascular disease 9 | 87
Prostatic Neoplasms 9 | 495
Asthma 8 | 385
Heart disease 8 | 306
Liver Cirrhosis, Experimental 8 | 769
Multiple myeloma 8 | 1,332
active ulcerative colitis 8 | 764
aldosterone-producing adenoma 8 | 665
cutaneous lupus erythematosus 8 | 1,057
dermatomyositis 8 | 966
non primary Sjogren syndrome sicca 8 | 891
substance-related disorder 8 | 162
Atherosclerosis 7 | 291
Cerebrovascular disease 7 | 238
Dementia 7 | 175
Major Depressive Disorder 7 | 301
esophageal adenocarcinoma 7 | 737
mucosa-associated lymphoid tissue lymphoma 7 | 484
pancreatic carcinoma 7 | 562
pancreatic ductal adenocarcinoma liver metastasis 7 | 1,962

Tissue

Female tissues 136 | 17,400
Endocrine System 135 | 18,159
Respiratory system 134 | 16,393
Skin and soft tissues 134 | 17,230
Blood and immune system 133 | 16,909
Digestive Tract 133 | 17,369
Male tissues 132 | 17,142
Liver and Pancreas 131 | 16,750
Urinary Tract 131 | 16,678
Nervous System 129 | 16,725
Cardiovascular System 123 | 15,192

Target Family

Non-IDG 78 | 12,091
Enzyme 28 | 4,145
Kinase 9 | 634
Transcription Factor 9 | 1,400
Transporter 8 | 473
Ion Channel 7 | 344
TF/Epigenetic 3 | 38
GPCR 2 | 408

GWAS Trait

Diastolic blood pressure 144 | 144
Obesity-related traits 569 | 569
Schizophrenia 533 | 533
Breast cancer 492 | 492
Body mass index 379 | 379
Height 369 | 369
Coronary artery disease 367 | 367
Blood protein levels 351 | 351
Post bronchodilator FEV1-FVC r... 308 | 308
Mean corpuscular volume 283 | 283
Platelet count 275 | 275
Intelligence (multi-trait anal... 267 | 267
Mean platelet volume 253 | 253
IgG glycosylation 250 | 250
Mean corpuscular hemoglobin 238 | 238
Inflammatory bowel disease 235 | 235
Plateletcrit 227 | 227
Crohn's disease 215 | 215
Type 2 diabetes 210 | 210
Red blood cell count 191 | 191
Monocyte count 183 | 183
Red cell distribution width 182 | 182
Eosinophil counts 180 | 180
Neuroticism 180 | 180
Platelet distribution width 174 | 174
Monocyte percentage of white c... 173 | 173
Post bronchodilator FEV1 173 | 173
Sum eosinophil basophil counts 173 | 173
White blood cell count 172 | 172
3-hydroxy-1-methylpropylmercap... 166 | 166
Eosinophil percentage of granu... 163 | 163
Eosinophil percentage of white... 163 | 163
Reticulocyte fraction of red c... 163 | 163
Ulcerative colitis 163 | 163
Granulocyte percentage of myel... 162 | 162
Itch intensity from mosquito b... 162 | 162
Systemic lupus erythematosus 159 | 159
High light scatter reticulocyt... 158 | 158
Lymphocyte counts 158 | 158
Reticulocyte count 158 | 158
Blood metabolite levels 157 | 157
Neutrophil count 154 | 154
High light scatter reticulocyt... 153 | 153
Neutrophil percentage of granu... 153 | 153
3-hydroxypropylmercapturic aci... 150 | 150
Tonsillectomy 149 | 149
Sum basophil neutrophil counts 140 | 140
Autism spectrum disorder or sc... 134 | 134
Myeloid white cell count 133 | 133
Granulocyte count 132 | 132
Sum neutrophil eosinophil coun... 129 | 129
Colorectal cancer 126 | 126
Alzheimer disease and age of o... 124 | 124
Multiple sclerosis 124 | 124
Cholesterol, total 123 | 123
Night sleep phenotypes 123 | 123
Lung cancer 122 | 122
Lymphocyte percentage of white... 122 | 122
Menarche (age at onset) 122 | 122
Neutrophil percentage of white... 121 | 121
Rheumatoid arthritis 121 | 121
Systolic blood pressure 120 | 120
Immature fraction of reticuloc... 118 | 118
Diisocyanate-induced asthma 116 | 116
HDL cholesterol 116 | 116
Allergic disease (asthma, hay ... 115 | 115
Educational attainment (years ... 114 | 114
Hematocrit 113 | 113
Hemoglobin concentration 112 | 112
LDL cholesterol 110 | 110
QT interval 110 | 110
Waist circumference adjusted f... 110 | 110
Mosquito bite size 107 | 107
Asthma 106 | 106
Lobe attachment (rater-scored ... 103 | 103
Peripheral arterial disease (t... 101 | 101
Pulse pressure 97 | 97
Bipolar disorder 94 | 94
Major depressive disorder 94 | 94
Prostate cancer 92 | 92
Parkinson's disease 90 | 90
Hip circumference adjusted for... 89 | 89
Metabolite levels 87 | 87
Triglycerides 87 | 87
Colonoscopy-negative controls ... 85 | 85
Mean corpuscular hemoglobin co... 85 | 85
Itch intensity from mosquito b... 84 | 84
Bipolar disorder and schizophr... 83 | 83
Resting heart rate 82 | 82
Macrophage inflammatory protei... 81 | 81
Migraine 81 | 81
Waist-to-hip ratio adjusted fo... 81 | 81
PR interval in Tripanosoma cru... 80 | 80
Cognitive performance 79 | 79
Glomerular filtration rate (cr... 78 | 78
Late-onset Alzheimer's disease 78 | 78
Waist circumference adjusted f... 75 | 75
Tuberculosis 73 | 73
Type 1 diabetes 73 | 73
Morning vs. evening chronotype 72 | 72

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
A disintegrin and metalloproteinase with thrombospondin motifs 7 ADAMTS7 Tbio Enzyme -1.43732 33.7 98
43 kDa receptor-associated protein of the synapse RAPSN Tbio Non-IDG -2.09902 132.1 134
Sodium bicarbonate cotransporter 3 SLC4A7 Tbio Transporter -1.82039 64.7 133
Grifin GRIFIN Tdark Non-IDG 0.00000 0
Protein TASOR FAM208A Tbio Non-IDG -0.45230 1.33 12
Pro-neuregulin-4, membrane-bound isoform NRG4 Tbio Non-IDG -1.33564 24.6 137
Putative helicase MOV-10 MOV10 Tbio Enzyme -1.55297 38.5 121
Protocadherin-18 PCDH18 Tbio Non-IDG -0.69395 5.31 87
Methylenetetrahydrofolate reductase MTHFR Tbio Enzyme -3.68447 5032.2 275