Development Level

Tbio 8 | 11,445
Tdark 2 | 6,588
Tchem 1 | 1,598

IMPC Phenotype

preweaning lethality, complete... 2 | 979
decreased bone mineral density 1 | 126
decreased total body fat amoun... 1 | 207
increased bone mineral content 1 | 108
increased circulating iron lev... 1 | 30
increased lean body mass 1 | 172
prenatal lethality prior to he... 1 | 87

Disease

Carcinoma 11 | 11,493
medulloblastoma, large-cell 9 | 6,241
atypical teratoid / rhabdoid tumor 6 | 5,112
glioblastoma 6 | 5,792
group 3 medulloblastoma 6 | 4,104
ovarian cancer 6 | 8,520
Kidney cancer 5 | 2,613
ependymoma 5 | 4,679
Astrocytoma, Pilocytic 4 | 3,081
astrocytic glioma 4 | 2,597
osteosarcoma 4 | 7,950
pituitary cancer 4 | 1,972
psoriasis 4 | 6,694
Breast cancer 3 | 3,578
Intellectual disability 3 | 1,016
Schizophrenia 3 | 1,160
adult high grade glioma 3 | 3,801
lung carcinoma 3 | 2,843
malignant mesothelioma 3 | 3,232
oligodendroglioma 3 | 2,850
primitive neuroectodermal tumor 3 | 3,035
subependymal giant cell astrocytoma 3 | 2,287
Actinomycosis 2 | 9
Alzheimer's disease 2 | 658
Cancer 2 | 2,499
Dull intelligence 2 | 645
Liver cancer 2 | 604
Low intelligence 2 | 645
Melanoma 2 | 711
Mental Retardation 2 | 645
Mental deficiency 2 | 645
Muscle hypotonia 2 | 571
Pick disease 2 | 1,894
Poor school performance 2 | 645
Skin cancer 2 | 469
Stomach Neoplasms 2 | 300
interstitial cystitis 2 | 2,312
intraductal papillary-mucinous adenoma (IPMA) 2 | 2,955
intraductal papillary-mucinous carcinoma (IPMC) 2 | 2,989
pancreatic ductal adenocarcinoma liver metastasis 2 | 1,962
posterior fossa group B ependymoma 2 | 416
substance-related disorder 2 | 162
tuberculosis 2 | 2,010
ulcerative colitis 2 | 1,819
Acquired metabolic disease 1 | 336
Acute monocytic leukemia 1 | 13
Adamantinoma 1 | 3
Adenocarcinoma 1 | 122
Adenoid Cystic Carcinoma 1 | 99
Alveolar rhabdomyosarcoma 1 | 7
Bladder Neoplasm 1 | 112
Blepharophimosis 1 | 70
Broad-based gait 1 | 19
Carcinoma of colon 1 | 32
Carcinoma, Adenoid Cystic 1 | 99
Carcinoma, Hepatocellular 1 | 228
Carcinoma, Transitional Cell 1 | 32
Celiac disease 1 | 116
Colorectal Neoplasms 1 | 243
Congenital Heart Defects 1 | 58
Coronary Restenosis 1 | 8
Downward slant of palpebral fissure 1 | 158
Esophageal Neoplasms 1 | 69
Flat face 1 | 52
Globe disease 1 | 67
Heart Defects, Congenital 1 | 37
Hypertrichosis 1 | 46
Hypoplasia of corpus callosum 1 | 90
Hypoplastic toes 1 | 29
Hypsarrhythmia 1 | 25
Infantile onset 1 | 238
Large intestine cancer 1 | 126
Leukemia, Monocytic, Acute 1 | 2
Leukemia, Myelocytic, Acute 1 | 120
Leukemia, Myeloid 1 | 18
Leukemia, Myeloid, Acute 1 | 105
Liver carcinoma 1 | 240
Lymphoid leukemia 1 | 160
Lymphoma 1 | 81
Malignant Squamous Cell Neoplasm 1 | 17
Microcephaly 1 | 166
Myeloid Leukemia 1 | 19
NUT Midline Carcinoma 1 | 4
Nonorganic psychosis 1 | 84
Periventricular nodular heterotopia 1 | 30
Pilocytic astrocytoma 1 | 56
Pseudobulbar palsy 1 | 11
Quadriparesis 1 | 8
Renal Cell Carcinoma 1 | 214
Sarcoma 1 | 62
Severe mental retardation (I.Q. 20-34) 1 | 99
Squamous cell carcinoma 1 | 129
Synophrys 1 | 40
Thin upper lip vermilion 1 | 67
Type 1 diabetes mellitus 6 1 | 2
Urinary Bladder Neoplasms 1 | 114
Wide nose 1 | 35
fascioscapulohumeral muscular dystrophy 1 | 100
non-small cell lung carcinoma 1 | 317
tuberculosis and treatment for 6 months 1 | 409

Tissue

Digestive Tract 11 | 17,369
Endocrine System 11 | 18,159
Female tissues 11 | 17,400
Nervous System 11 | 16,725
Urinary Tract 11 | 16,678
Blood and immune system 10 | 16,909
Male tissues 10 | 17,142
Skin and soft tissues 10 | 17,230
Liver and Pancreas 9 | 16,750
Respiratory system 9 | 16,393
Cardiovascular System 8 | 15,192

Target Family

Non-IDG 8 | 12,091
Epigenetic 1 | 242
Kinase 1 | 634
Transcription Factor 1 | 1,400

GWAS Trait

Depression 11 | 11
Obesity-related traits 569 | 569
Schizophrenia 533 | 533
Breast cancer 492 | 492
Body mass index 379 | 379
Height 369 | 369
Coronary artery disease 367 | 367
Blood protein levels 351 | 351
Post bronchodilator FEV1-FVC r... 308 | 308
Mean corpuscular volume 283 | 283
Platelet count 275 | 275
Intelligence (multi-trait anal... 267 | 267
Mean platelet volume 253 | 253
IgG glycosylation 250 | 250
Mean corpuscular hemoglobin 238 | 238
Inflammatory bowel disease 235 | 235
Plateletcrit 227 | 227
Crohn's disease 215 | 215
Type 2 diabetes 210 | 210
Red blood cell count 191 | 191
Monocyte count 183 | 183
Red cell distribution width 182 | 182
Eosinophil counts 180 | 180
Neuroticism 180 | 180
Platelet distribution width 174 | 174
Monocyte percentage of white c... 173 | 173
Post bronchodilator FEV1 173 | 173
Sum eosinophil basophil counts 173 | 173
White blood cell count 172 | 172
3-hydroxy-1-methylpropylmercap... 166 | 166
Eosinophil percentage of granu... 163 | 163
Eosinophil percentage of white... 163 | 163
Reticulocyte fraction of red c... 163 | 163
Ulcerative colitis 163 | 163
Granulocyte percentage of myel... 162 | 162
Itch intensity from mosquito b... 162 | 162
Systemic lupus erythematosus 159 | 159
High light scatter reticulocyt... 158 | 158
Lymphocyte counts 158 | 158
Reticulocyte count 158 | 158
Blood metabolite levels 157 | 157
Neutrophil count 154 | 154
High light scatter reticulocyt... 153 | 153
Neutrophil percentage of granu... 153 | 153
3-hydroxypropylmercapturic aci... 150 | 150
Tonsillectomy 149 | 149
Diastolic blood pressure 144 | 144
Sum basophil neutrophil counts 140 | 140
Autism spectrum disorder or sc... 134 | 134
Myeloid white cell count 133 | 133
Granulocyte count 132 | 132
Sum neutrophil eosinophil coun... 129 | 129
Colorectal cancer 126 | 126
Alzheimer disease and age of o... 124 | 124
Multiple sclerosis 124 | 124
Cholesterol, total 123 | 123
Night sleep phenotypes 123 | 123
Lung cancer 122 | 122
Lymphocyte percentage of white... 122 | 122
Menarche (age at onset) 122 | 122
Neutrophil percentage of white... 121 | 121
Rheumatoid arthritis 121 | 121
Systolic blood pressure 120 | 120
Immature fraction of reticuloc... 118 | 118
Diisocyanate-induced asthma 116 | 116
HDL cholesterol 116 | 116
Allergic disease (asthma, hay ... 115 | 115
Educational attainment (years ... 114 | 114
Hematocrit 113 | 113
Hemoglobin concentration 112 | 112
LDL cholesterol 110 | 110
QT interval 110 | 110
Waist circumference adjusted f... 110 | 110
Mosquito bite size 107 | 107
Asthma 106 | 106
Lobe attachment (rater-scored ... 103 | 103
Peripheral arterial disease (t... 101 | 101
Pulse pressure 97 | 97
Bipolar disorder 94 | 94
Major depressive disorder 94 | 94
Prostate cancer 92 | 92
Parkinson's disease 90 | 90
Hip circumference adjusted for... 89 | 89
Metabolite levels 87 | 87
Triglycerides 87 | 87
Colonoscopy-negative controls ... 85 | 85
Mean corpuscular hemoglobin co... 85 | 85
Itch intensity from mosquito b... 84 | 84
Bipolar disorder and schizophr... 83 | 83
Resting heart rate 82 | 82
Macrophage inflammatory protei... 81 | 81
Migraine 81 | 81
Waist-to-hip ratio adjusted fo... 81 | 81
PR interval in Tripanosoma cru... 80 | 80
Cognitive performance 79 | 79
Glomerular filtration rate (cr... 78 | 78
Late-onset Alzheimer's disease 78 | 78
Waist circumference adjusted f... 75 | 75
Tuberculosis 73 | 73
Type 1 diabetes 73 | 73
Morning vs. evening chronotype 72 | 72

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Brefeldin A-inhibited guanine nucleotide-exchange protein 2 ARFGEF2 Tbio Non-IDG -1.15371 14.4 81
Cortactin-binding protein 2 CTTNBP2 Tbio Non-IDG -2.42985 261.1 59
Kinase suppressor of Ras 2 KSR2 Tbio Kinase -0.90433 8.77 280
VPS10 domain-containing receptor SorCS3 SORCS3 Tbio Non-IDG -0.70549 6.30 49
Folliculin-interacting protein 2 FNIP2 Tbio Non-IDG -0.75931 4.81 135
Histone-lysine N-methyltransferase 2A KMT2A Tchem Epigenetic -2.88228 736.0 334
Uncharacterized protein C12orf42 C12orf42 Tdark Non-IDG 0.30 0.50 48
Contactin-5 CNTN5 Tbio Non-IDG -2.54880 296.6 100
Netrin receptor DCC DCC Tbio Non-IDG -2.05574 103.6 222
Mastermind-like protein 3 MAML3 Tbio Non-IDG -0.91427 7.57 116