Development Level

Tbio 70 | 10,625
Tchem 19 | 1,890
Tdark 16 | 7,003
Tclin 5 | 602

Collection

GPCR: IDG Consortium (Complete/Control) 2 | 24

IMPC Phenotype

increased mean corpuscular hem... 3 | 93
abnormal bone structure 2 | 131
abnormal lens morphology 2 | 73
decreased CD4-positive, CD25-p... 2 | 24
decreased body weight 2 | 174
decreased effector memory CD8-... 2 | 24
decreased gamma-delta T cell n... 2 | 18
decreased neutrophil cell numb... 2 | 37
increased circulating HDL chol... 2 | 63
increased circulating choleste... 2 | 53
increased circulating serum al... 2 | 25
increased effector memory CD4-... 2 | 15
increased neutrophil cell numb... 2 | 15
preweaning lethality, complete... 2 | 633
abnormal behavior 1 | 226
abnormal coping response 1 | 12
abnormal embryo size 1 | 112
abnormal epididymis morphology 1 | 31
abnormal heart morphology 1 | 51
abnormal retinal blood vessel ... 1 | 18
abnormal retinal vasculature m... 1 | 15
abnormal skin morphology 1 | 23
decreased B cell number 1 | 30
decreased CD4-positive, alpha ... 1 | 19
decreased CD8-positive, alpha-... 1 | 26
decreased CD8-positive, naive ... 1 | 5
decreased IgM level 1 | 1
decreased T cell number 1 | 31
decreased alpha-beta T cell nu... 1 | 12
decreased body length 1 | 108
decreased bone mineral content 1 | 157
decreased bone mineral density 1 | 126
decreased circulating HDL chol... 1 | 77
decreased circulating creatini... 1 | 31
decreased circulating insulin ... 1 | 75
decreased circulating phosphat... 1 | 15
decreased fasted circulating g... 1 | 49
decreased grip strength 1 | 123
decreased lean body mass 1 | 195
decreased lymphocyte cell numb... 1 | 9
decreased mature B cell number 1 | 25
decreased rib number 1 | 59
enlarged epididymis 1 | 27
enlarged heart 1 | 111
female infertility 1 | 34
increased CD4-positive, CD25-p... 1 | 18
increased CD4-positive, alpha ... 1 | 15
increased KLRG1+ CD4 alpha bet... 1 | 5
increased KLRG1+ CD8 alpha bet... 1 | 2
increased KLRG1-positive CD4-n... 1 | 1
increased KLRG1-positive CD4-p... 1 | 3
increased KLRG1-positive NK ce... 1 | 9
increased KLRG1-positive T-hel... 1 | 2
increased KLRG1-positive gamma... 1 | 2
increased Ly6C low monocyte nu... 1 | 8
increased NK cell number 1 | 19
increased body length 1 | 20
increased circulating alkaline... 1 | 119
increased circulating free fat... 1 | 17
increased effector memory CD8-... 1 | 14
increased effector memory T-he... 1 | 5
increased eosinophil cell numb... 1 | 9
increased fasted circulating g... 1 | 68
increased grip strength 1 | 83
increased hemoglobin content 1 | 45
increased leukocyte cell numbe... 1 | 37
increased memory CD4-positive,... 1 | 3
increased memory-marker CD4-ne... 1 | 1
increased monocyte cell number 1 | 27
increased myeloid cell number 1 | 2
increased rib number 1 | 41
increased total body fat amoun... 1 | 57
male infertility 1 | 62
preweaning lethality, incomple... 1 | 260
small superior vagus ganglion 1 | 20

Disease

Crohn's disease 86 | 304
ovarian cancer 61 | 8,491
osteosarcoma 58 | 7,933
Crohn Disease 56 | 97
Inflammatory Bowel Diseases 49 | 87
psoriasis 44 | 6,685
glioblastoma 42 | 5,572
ulcerative colitis 39 | 2,087
medulloblastoma, large-cell 38 | 6,234
lung cancer 35 | 4,473
atypical teratoid / rhabdoid tumor 29 | 4,369
pediatric high grade glioma 25 | 2,712
pilocytic astrocytoma 25 | 3,086
primitive neuroectodermal tumor 25 | 3,031
Breast cancer 24 | 3,098
Rheumatoid Arthritis 24 | 1,170
lung carcinoma 24 | 2,844
oligodendroglioma 24 | 2,849
Carcinoma 23 | 2,147
invasive ductal carcinoma 22 | 2,950
intraductal papillary-mucinous adenoma (IPMA) 21 | 2,956
malignant mesothelioma 21 | 3,163
tuberculosis 21 | 1,563
Cancer 20 | 2,346
interstitial cystitis 19 | 2,299
intraductal papillary-mucinous neoplasm (IPMN) 19 | 3,289
non-small cell lung cancer 19 | 2,798
intraductal papillary-mucinous carcinoma (IPMC) 18 | 2,988
lung adenocarcinoma 17 | 2,714
Common variable immunodeficiency 16 | 98
Pick disease 16 | 1,893
Multiple Sclerosis 15 | 498
astrocytic glioma 15 | 2,241
cystic fibrosis 15 | 1,670
ependymoma 15 | 2,514
group 3 medulloblastoma 15 | 2,254
group 4 medulloblastoma 14 | 1,875
pancreatic cancer 14 | 2,300
pituitary cancer 14 | 1,972
primary Sjogren syndrome 14 | 788
subependymal giant cell astrocytoma 14 | 2,287
colon cancer 12 | 1,475
diabetes mellitus 12 | 1,663
posterior fossa group A ependymoma 12 | 1,511
Atopic dermatitis 11 | 944
adult high grade glioma 11 | 2,148
astrocytoma 11 | 1,493
atypical teratoid/rhabdoid tumor 11 | 1,095
medulloblastoma 11 | 1,524
Celiac disease 10 | 112
ductal carcinoma in situ 10 | 1,745
pancreatic ductal adenocarcinoma liver metastasis 10 | 1,795
posterior fossa group B ependymoma 10 | 1,530
Gastrointestinal system disease 9 | 50
Type 1 diabetes mellitus 9 | 104
cutaneous lupus erythematosus 9 | 1,056
mucosa-associated lymphoid tissue lymphoma 9 | 480
nasopharyngeal carcinoma 9 | 1,056
systemic lupus erythematosus 9 | 172
Acquired metabolic disease 8 | 267
Alzheimer's disease 8 | 644
Diabetes Mellitus, Insulin-Dependent 8 | 77
Kidney disease 8 | 397
Mammary Neoplasms 8 | 410
active Crohn's disease 8 | 918
acute myeloid leukemia 8 | 785
breast carcinoma 8 | 1,614
esophageal adenocarcinoma 8 | 737
gastric carcinoma 8 | 832
juvenile dermatomyositis 8 | 1,189
non primary Sjogren syndrome sicca 8 | 840
primary pancreatic ductal adenocarcinoma 8 | 1,271
Asthma 7 | 349
Diabetes Mellitus, Non-Insulin-Dependent 7 | 161
IGA Glomerulonephritis 7 | 454
Inflammatory bowel disease 7 | 142
Prostate cancer 7 | 172
acute quadriplegic myopathy 7 | 1,157
spina bifida 7 | 1,064
Down syndrome 6 | 548
Lupus Erythematosus, Systemic 6 | 73
Multiple myeloma 6 | 1,327
Neurodegenerative disease 6 | 383
Obesity 6 | 616
Waldenstrons macroglobulinemia 6 | 764
adrenocortical carcinoma 6 | 1,427
sonic hedgehog group medulloblastoma 6 | 1,482
tuberculosis and treatment for 6 months 6 | 686
Endometriosis 5 | 535
Prostatic Neoplasms 5 | 471
Type 2 diabetes mellitus 5 | 192
Vascular disease 5 | 281
Vitiligo 5 | 71
active ulcerative colitis 5 | 477
aldosterone-producing adenoma 5 | 664
dermatomyositis 5 | 966
interstitial lung disease 5 | 292
progressive supranuclear palsy 5 | 674
sarcoidosis 5 | 368
urothelial carcinoma 5 | 318

Tissue

Digestive Tract 109 | 18,472
Nervous System 109 | 18,560
Cardiovascular System 108 | 17,957
Endocrine System 108 | 18,511
Female tissues 108 | 18,646
Urinary Tract 108 | 18,443
Blood and immune system 107 | 17,994
Liver and Pancreas 107 | 18,135
Male tissues 107 | 17,968
Skin and soft tissues 107 | 18,114
Respiratory system 105 | 17,483

Target Family

Non-IDG 59 | 11,969
Enzyme 26 | 4,146
Transcription Factor 10 | 1,400
Kinase 7 | 634
GPCR 3 | 408
Epigenetic 2 | 242
Nuclear Receptor 1 | 48
TF/Epigenetic 1 | 38
Transporter 1 | 473

GWAS Trait

Crohn's disease 110 | 110
Obesity-related traits 380 | 380
Schizophrenia 334 | 334
Height 250 | 250
Post bronchodilator FEV1-FVC r... 191 | 191
Body mass index 180 | 180
IgG glycosylation 162 | 162
Inflammatory bowel disease 117 | 117
Post bronchodilator FEV1 111 | 111
Blood metabolite levels 103 | 103
Type 2 diabetes 94 | 94
3-hydroxy-1-methylpropylmercap... 93 | 93
3-hydroxypropylmercapturic aci... 92 | 92
Ulcerative colitis 89 | 89
Platelet count 79 | 79
Systemic lupus erythematosus 78 | 78
HDL cholesterol 76 | 76
Rheumatoid arthritis 74 | 74
Cholesterol, total 73 | 73
Menarche (age at onset) 73 | 73
Diisocyanate-induced asthma 72 | 72
Multiple sclerosis 68 | 68
LDL cholesterol 67 | 67
QT interval 58 | 58
Metabolite levels 55 | 55
Atopic dermatitis 54 | 54
Bipolar disorder and schizophr... 54 | 54
Breast cancer 54 | 54
Prostate cancer 54 | 54
Triglycerides 53 | 53
Bipolar disorder 52 | 52
HIV-1 control 50 | 50
Post bronchodilator FEV1-FVC r... 50 | 50
HIV-1 viral setpoint 49 | 49
Cognitive performance 48 | 48
Amyotrophic lateral sclerosis ... 46 | 46
Bone mineral density 46 | 46
Clozapine-induced agranulocyto... 46 | 46
Attention deficit hyperactivit... 44 | 44
Blood pressure 44 | 44
Coronary heart disease 43 | 43
Glomerular filtration rate (cr... 43 | 43
Parkinson's disease 43 | 43
Type 1 diabetes 42 | 42
PR interval in Tripanosoma cru... 40 | 40
Post bronchodilator FEV1 in CO... 39 | 39
Alzheimer's disease (cognitive... 38 | 38
Educational attainment 38 | 38
Pulmonary function 38 | 38
Diffuse large B cell lymphoma 37 | 37
Inflammatory skin disease 37 | 37
Beta-2 microglubulin plasma le... 36 | 36
Glucose homeostasis traits 36 | 36
Urate levels 36 | 36
Blood metabolite ratios 35 | 35
Psoriasis 35 | 35
Autism spectrum disorder, atte... 34 | 34
Migraine 33 | 33
Coronary artery disease 32 | 32
Metabolic traits 32 | 32
Waist-to-hip ratio adjusted fo... 32 | 32
Cognitive function 31 | 31
Colorectal cancer 31 | 31
Amyotrophic lateral sclerosis 30 | 30
Myopia (pathological) 30 | 30
Obesity 30 | 30
Response to amphetamines 30 | 30
Systolic blood pressure 30 | 30
Alzheimer's disease (late onse... 29 | 29
Celiac disease 29 | 29
Phospholipid levels (plasma) 29 | 29
Red blood cell traits 29 | 29
Advanced age-related macular d... 28 | 28
Dental caries 28 | 28
Fibrinogen levels 28 | 28
Parental extreme longevity (95... 28 | 28
Pulmonary function (interactio... 28 | 28
Asthma 27 | 27
Cognitive decline rate in late... 27 | 27
Glomerular filtration rate in ... 27 | 27
Longevity 27 | 27
Mean platelet volume 27 | 27
Chronic kidney disease 26 | 26
Diabetic kidney disease 26 | 26
Diastolic blood pressure 26 | 26
Coronary artery calcification 25 | 25
Metabolic syndrome 25 | 25
Pancreatic cancer 25 | 25
Protein quantitative trait loc... 25 | 25
Hypertension 24 | 24
Migraine - clinic-based 24 | 24
Parental longevity (combined p... 24 | 24
Primary biliary cirrhosis 24 | 24
Thiazide-induced adverse metab... 24 | 24
Menopause (age at onset) 23 | 23
Response to antipsychotic trea... 23 | 23
Age-related macular degenerati... 22 | 22
Immune response to smallpox va... 22 | 22
Mild influenza (H1N1) infectio... 22 | 22
Sudden cardiac arrest 22 | 22

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Thyroid adenoma-associated protein THADA Tbio Non-IDG -1.50722 29.2 46
Endoplasmic reticulum aminopeptidase 2 ERAP2 Tchem Enzyme -1.68056 46.0 70
Transcription regulator protein BACH2 BACH2 Tbio Transcription Factor -1.84608 77.3 159
Signal transducer and activator of transcription 3 STAT3 Tchem Transcription Factor -3.75815 5706.6 1539
R-spondin-3 RSPO3 Tbio Non-IDG -1.18455 17.3 94
Transmembrane protein 258 TMEM258 Tdark Non-IDG -0.24304 1.54 5
Integrator complex subunit 11 CPSF3L Tbio Non-IDG -0.79472 5.46 101
F-BAR and double SH3 domains protein 2 FCHSD2 Tbio Non-IDG -1.52274 34.3 58
Acidic fibroblast growth factor intracellular-binding protein FIBP Tbio Non-IDG -0.71354 6.07 97
Cadherin EGF LAG seven-pass G-type receptor 3 CELSR3 Tbio GPCR -1.34279 23.6 177