Development Level

Tbio 48 | 11,445
Tchem 7 | 1,598
Tclin 5 | 613
Tdark 5 | 6,588

IMPC Phenotype

preweaning lethality, complete... 6 | 979
abnormal behavior 3 | 298
embryonic lethality prior to o... 3 | 239
embryonic lethality prior to t... 3 | 278
decreased circulating HDL chol... 2 | 68
decreased circulating choleste... 2 | 93
decreased mean corpuscular vol... 2 | 79
enlarged heart 2 | 210
preweaning lethality, incomple... 2 | 499
abnormal bone mineralization 1 | 38
abnormal coat-hair pigmentatio... 1 | 64
abnormal cornea morphology 1 | 31
abnormal embryo size 1 | 220
abnormal epididymis morphology 1 | 42
abnormal gait 1 | 69
abnormal heart morphology 1 | 162
abnormal lens morphology 1 | 81
abnormal optic disc morphology 1 | 10
abnormal posture 1 | 2
abnormal response to tactile s... 1 | 17
abnormal seminal vesicle morph... 1 | 114
abnormal snout morphology 1 | 23
abnormal startle reflex 1 | 15
abnormal tooth morphology 1 | 24
abnormal vibrissa morphology 1 | 25
absent vibrissae 1 | 12
corneal opacity 1 | 32
decreased CD4-positive, alpha ... 1 | 7
decreased CD8-positive, alpha-... 1 | 8
decreased T cell number 1 | 15
decreased body length 1 | 101
decreased body weight 1 | 161
decreased bone mineral density 1 | 126
decreased circulating LDL chol... 1 | 38
decreased circulating alkaline... 1 | 46
decreased circulating calcium ... 1 | 36
decreased circulating serum al... 1 | 82
decreased circulating total pr... 1 | 49
decreased circulating triglyce... 1 | 79
decreased coping response 1 | 8
decreased eosinophil cell numb... 1 | 24
decreased heart left ventricle... 1 | 28
decreased hematocrit 1 | 46
decreased hemoglobin content 1 | 68
decreased lymphocyte cell numb... 1 | 83
decreased respiratory quotient 1 | 16
decreased startle reflex 1 | 75
edema 1 | 59
embryonic growth retardation 1 | 106
enlarged epididymis 1 | 31
enlarged uterus 1 | 11
hydrometra 1 | 53
hypoactivity 1 | 132
increased bone mineral content 1 | 108
increased circulating alkaline... 1 | 122
increased fasted circulating g... 1 | 76
increased mean platelet volume 1 | 45
increased monocyte cell number 1 | 63
irregularly shaped pupil 1 | 7
male infertility 1 | 123
prenatal lethality 1 | 28
prenatal lethality prior to he... 1 | 87
small kidney 1 | 16
small superior vagus ganglion 1 | 74
small testis 1 | 58

Disease

Cardiovascular system disease 45 | 246
Carcinoma 44 | 11,493
ovarian cancer 34 | 8,520
osteosarcoma 32 | 7,950
atypical teratoid / rhabdoid tumor 31 | 5,112
glioblastoma 31 | 5,792
lung cancer 30 | 4,740
medulloblastoma, large-cell 28 | 6,241
psoriasis 28 | 6,694
Coronary artery disease 25 | 268
adult high grade glioma 21 | 3,801
invasive ductal carcinoma 21 | 2,951
Breast cancer 19 | 3,578
intraductal papillary-mucinous adenoma (IPMA) 18 | 2,955
non-small cell lung cancer 18 | 2,890
primitive neuroectodermal tumor 18 | 3,035
group 3 medulloblastoma 17 | 4,104
intraductal papillary-mucinous neoplasm (IPMN) 17 | 3,291
lung adenocarcinoma 17 | 2,716
Astrocytoma, Pilocytic 16 | 3,081
diabetes mellitus 16 | 1,728
ependymoma 16 | 4,679
Kidney cancer 15 | 2,613
lung carcinoma 15 | 2,843
pancreatic ductal adenocarcinoma liver metastasis 15 | 1,962
Cancer 14 | 2,499
ductal carcinoma in situ 14 | 1,745
intraductal papillary-mucinous carcinoma (IPMC) 14 | 2,989
pancreatic cancer 14 | 2,398
pituitary cancer 13 | 1,972
tuberculosis 13 | 2,010
cystic fibrosis 12 | 1,696
interstitial cystitis 12 | 2,312
malignant mesothelioma 12 | 3,232
subependymal giant cell astrocytoma 12 | 2,287
ulcerative colitis 12 | 1,819
Atherosclerosis 11 | 291
astrocytic glioma 11 | 2,597
breast carcinoma 11 | 1,638
juvenile dermatomyositis 10 | 1,187
oligodendroglioma 10 | 2,850
Pick disease 9 | 1,894
acute quadriplegic myopathy 9 | 1,158
adrenocortical carcinoma 9 | 1,428
gastric carcinoma 9 | 807
Duchenne muscular dystrophy 8 | 601
Myocardial Infarction 8 | 151
colon cancer 8 | 1,478
primary Sjogren syndrome 8 | 735
Hypertension 7 | 396
Prostatic Neoplasms 7 | 495
Schizophrenia 7 | 1,160
Waldenstrons macroglobulinemia 7 | 765
active ulcerative colitis 7 | 764
dermatomyositis 7 | 966
substance-related disorder 7 | 162
Atopic dermatitis 6 | 952
Cerebrovascular disease 6 | 238
Kidney disease 6 | 430
Liver Cirrhosis, Experimental 6 | 769
Rheumatoid arthritis 6 | 1,191
Type 2 diabetes mellitus 6 | 272
Vascular disease 6 | 319
group 4 medulloblastoma 6 | 1,855
interstitial lung disease 6 | 298
limb girdle muscular dystrophy 2A 6 | 213
primary pancreatic ductal adenocarcinoma 6 | 1,109
Autosomal recessive predisposition 5 | 1,442
Breast Neoplasms 5 | 445
Cognitive delay 5 | 608
Diabetes Mellitus, Type 2 5 | 142
Diarrhea 5 | 253
Epilepsy 5 | 792
Global developmental delay 5 | 608
Hepatomegaly 5 | 285
Hypertensive disease 5 | 292
Intellectual disability 5 | 1,016
Lipid metabolism disorder 5 | 114
Melanoma 5 | 711
Mental and motor retardation 5 | 608
Polycystic ovary syndrome 5 | 360
Renal Cell Carcinoma 5 | 214
Seizures 5 | 596
active Crohn's disease 5 | 922
autosomal dominant Emery-Dreifuss muscular dystrophy 5 | 510
hepatocellular carcinoma 5 | 547
medulloblastoma 5 | 720
spina bifida 5 | 1,074
Alzheimer's disease 4 | 658
Asthma 4 | 385
Bipolar Disorder 4 | 666
Dull intelligence 4 | 645
Essential Hypertension 4 | 94
Heart disease 4 | 306
acute myeloid leukemia 4 | 783
aldosterone-producing adenoma 4 | 665
fibroadenoma 4 | 559
nasopharyngeal carcinoma 4 | 1,058
pediatric high grade glioma 4 | 1,064
urothelial carcinoma 4 | 318

Tissue

Endocrine System 61 | 18,159
Digestive Tract 60 | 17,369
Female tissues 60 | 17,400
Male tissues 60 | 17,142
Urinary Tract 60 | 16,678
Liver and Pancreas 59 | 16,750
Skin and soft tissues 59 | 17,230
Nervous System 57 | 16,725
Blood and immune system 56 | 16,909
Respiratory system 55 | 16,393
Cardiovascular System 49 | 15,192

Target Family

Non-IDG 35 | 12,091
Enzyme 18 | 4,145
Transcription Factor 6 | 1,400
Transporter 2 | 473
Epigenetic 1 | 242
GPCR 1 | 408
Ion Channel 1 | 344
Kinase 1 | 634

GWAS Trait

Coronary heart disease 65 | 65
Obesity-related traits 569 | 569
Schizophrenia 533 | 533
Breast cancer 492 | 492
Body mass index 379 | 379
Height 369 | 369
Coronary artery disease 367 | 367
Blood protein levels 351 | 351
Post bronchodilator FEV1-FVC r... 308 | 308
Mean corpuscular volume 283 | 283
Platelet count 275 | 275
Intelligence (multi-trait anal... 267 | 267
Mean platelet volume 253 | 253
IgG glycosylation 250 | 250
Mean corpuscular hemoglobin 238 | 238
Inflammatory bowel disease 235 | 235
Plateletcrit 227 | 227
Crohn's disease 215 | 215
Type 2 diabetes 210 | 210
Red blood cell count 191 | 191
Monocyte count 183 | 183
Red cell distribution width 182 | 182
Eosinophil counts 180 | 180
Neuroticism 180 | 180
Platelet distribution width 174 | 174
Monocyte percentage of white c... 173 | 173
Post bronchodilator FEV1 173 | 173
Sum eosinophil basophil counts 173 | 173
White blood cell count 172 | 172
3-hydroxy-1-methylpropylmercap... 166 | 166
Eosinophil percentage of granu... 163 | 163
Eosinophil percentage of white... 163 | 163
Reticulocyte fraction of red c... 163 | 163
Ulcerative colitis 163 | 163
Granulocyte percentage of myel... 162 | 162
Itch intensity from mosquito b... 162 | 162
Systemic lupus erythematosus 159 | 159
High light scatter reticulocyt... 158 | 158
Lymphocyte counts 158 | 158
Reticulocyte count 158 | 158
Blood metabolite levels 157 | 157
Neutrophil count 154 | 154
High light scatter reticulocyt... 153 | 153
Neutrophil percentage of granu... 153 | 153
3-hydroxypropylmercapturic aci... 150 | 150
Tonsillectomy 149 | 149
Diastolic blood pressure 144 | 144
Sum basophil neutrophil counts 140 | 140
Autism spectrum disorder or sc... 134 | 134
Myeloid white cell count 133 | 133
Granulocyte count 132 | 132
Sum neutrophil eosinophil coun... 129 | 129
Colorectal cancer 126 | 126
Alzheimer disease and age of o... 124 | 124
Multiple sclerosis 124 | 124
Cholesterol, total 123 | 123
Night sleep phenotypes 123 | 123
Lung cancer 122 | 122
Lymphocyte percentage of white... 122 | 122
Menarche (age at onset) 122 | 122
Neutrophil percentage of white... 121 | 121
Rheumatoid arthritis 121 | 121
Systolic blood pressure 120 | 120
Immature fraction of reticuloc... 118 | 118
Diisocyanate-induced asthma 116 | 116
HDL cholesterol 116 | 116
Allergic disease (asthma, hay ... 115 | 115
Educational attainment (years ... 114 | 114
Hematocrit 113 | 113
Hemoglobin concentration 112 | 112
LDL cholesterol 110 | 110
QT interval 110 | 110
Waist circumference adjusted f... 110 | 110
Mosquito bite size 107 | 107
Asthma 106 | 106
Lobe attachment (rater-scored ... 103 | 103
Peripheral arterial disease (t... 101 | 101
Pulse pressure 97 | 97
Bipolar disorder 94 | 94
Major depressive disorder 94 | 94
Prostate cancer 92 | 92
Parkinson's disease 90 | 90
Hip circumference adjusted for... 89 | 89
Metabolite levels 87 | 87
Triglycerides 87 | 87
Colonoscopy-negative controls ... 85 | 85
Mean corpuscular hemoglobin co... 85 | 85
Itch intensity from mosquito b... 84 | 84
Bipolar disorder and schizophr... 83 | 83
Resting heart rate 82 | 82
Macrophage inflammatory protei... 81 | 81
Migraine 81 | 81
Waist-to-hip ratio adjusted fo... 81 | 81
PR interval in Tripanosoma cru... 80 | 80
Cognitive performance 79 | 79
Glomerular filtration rate (cr... 78 | 78
Late-onset Alzheimer's disease 78 | 78
Waist circumference adjusted f... 75 | 75
Tuberculosis 73 | 73
Type 1 diabetes 73 | 73
Morning vs. evening chronotype 72 | 72

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Ankyrin repeat, SAM and basic leucine zipper domain-containing protein 1 ASZ1 Tbio Non-IDG -2.81661 644.9 107
A disintegrin and metalloproteinase with thrombospondin motifs 7 ADAMTS7 Tbio Enzyme -1.43732 33.7 98
Vascular endothelial growth factor receptor 1 FLT1 Tclin Kinase -3.38913 2189.4 953
Cadherin EGF LAG seven-pass G-type receptor 2 CELSR2 Tbio GPCR -1.22995 16.7 139
Histo-blood group ABO system transferase ABO Tbio Enzyme 0.00000 0
Probable E3 ubiquitin-protein ligase HECTD4 HECTD4 Tbio Enzyme -1.02570 11.0 0
Seizure 6-like protein SEZ6L Tbio Non-IDG -0.86297 6.90 49
Telomerase-binding protein EST1A SMG6 Tbio Enzyme -1.48788 32.6 37
Transcription factor 21 TCF21 Tbio Transcription Factor -1.80598 67.7 120
Hemogen HEMGN Tbio Non-IDG -1.29360 21.5 132