Development Level

Tbio 15 | 11,445
Tclin 2 | 613
Tchem 1 | 1,598

IMPC Phenotype

preweaning lethality, complete... 3 | 979
embryonic lethality prior to t... 2 | 278
abnormal coat-hair pigmentatio... 1 | 64
abnormal cornea morphology 1 | 31
abnormal heart morphology 1 | 162
abnormal posture 1 | 2
abnormal snout morphology 1 | 23
decreased body length 1 | 101
decreased body weight 1 | 161
decreased circulating triglyce... 1 | 79
decreased coping response 1 | 8
decreased hematocrit 1 | 46
decreased hemoglobin content 1 | 68
decreased lymphocyte cell numb... 1 | 83
decreased startle reflex 1 | 75
embryonic lethality prior to o... 1 | 239
enlarged heart 1 | 210
increased bone mineral content 1 | 108
increased monocyte cell number 1 | 63
male infertility 1 | 123
prenatal lethality prior to he... 1 | 87

Disease

Carcinoma 13 | 11,493
lung cancer 11 | 4,740
Coronary artery disease 9 | 268
atypical teratoid / rhabdoid tumor 9 | 5,112
glioblastoma 9 | 5,792
ovarian cancer 9 | 8,520
Cardiovascular system disease 8 | 246
adult high grade glioma 8 | 3,801
medulloblastoma, large-cell 8 | 6,241
osteosarcoma 8 | 7,950
psoriasis 7 | 6,694
malignant mesothelioma 6 | 3,232
non-small cell lung cancer 6 | 2,890
Breast cancer 5 | 3,578
Myocardial Infarction 5 | 151
Schizophrenia 5 | 1,160
astrocytic glioma 5 | 2,597
group 3 medulloblastoma 5 | 4,104
intraductal papillary-mucinous neoplasm (IPMN) 5 | 3,291
invasive ductal carcinoma 5 | 2,951
oligodendroglioma 5 | 2,850
tuberculosis 5 | 2,010
Astrocytoma, Pilocytic 4 | 3,081
Atherosclerosis 4 | 291
Cancer 4 | 2,499
Kidney cancer 4 | 2,613
cystic fibrosis 4 | 1,696
ductal carcinoma in situ 4 | 1,745
intraductal papillary-mucinous adenoma (IPMA) 4 | 2,955
intraductal papillary-mucinous carcinoma (IPMC) 4 | 2,989
lung adenocarcinoma 4 | 2,716
primitive neuroectodermal tumor 4 | 3,035
Essential Hypertension 3 | 94
Kidney disease 3 | 430
Lipid metabolism disorder 3 | 114
Liver cancer 3 | 604
Pick disease 3 | 1,894
Vascular disease 3 | 319
diabetes mellitus 3 | 1,728
ependymoma 3 | 4,679
lung carcinoma 3 | 2,843
medulloblastoma 3 | 720
pancreatic cancer 3 | 2,398
pancreatic ductal adenocarcinoma liver metastasis 3 | 1,962
spina bifida 3 | 1,074
ulcerative colitis 3 | 1,819
Amyotrophic lateral sclerosis 2 | 451
Broad flat nasal bridge 2 | 236
Celiac disease 2 | 116
Cerebrovascular accident 2 | 63
Cerebrovascular disease 2 | 238
Cognitive delay 2 | 608
Coronary Disease 2 | 25
Dental caries 2 | 164
Depressive disorder 2 | 409
Diabetes Mellitus, Type 2 2 | 142
Dull intelligence 2 | 645
Endometriosis 2 | 540
Epilepsy 2 | 792
Global developmental delay 2 | 608
Heart disease 2 | 306
Hypertension 2 | 396
Immune system cancer 2 | 140
Intellectual disability 2 | 1,016
Intracranial aneurysm 2 | 24
Low intelligence 2 | 645
Lymphoid leukemia 2 | 160
Mental Retardation 2 | 645
Mental and motor retardation 2 | 608
Mental deficiency 2 | 645
Multiple myeloma 2 | 1,332
Muscle hypotonia 2 | 571
Nasal bridge wide 2 | 236
Neurodegenerative disease 2 | 414
Ovarian Neoplasms 2 | 102
Poor school performance 2 | 645
Seizures 2 | 596
Small head 2 | 374
Stroke 2 | 33
Type 2 diabetes mellitus 2 | 272
Waldenstrons macroglobulinemia 2 | 765
active ulcerative colitis 2 | 764
acute quadriplegic myopathy 2 | 1,158
adrenocortical carcinoma 2 | 1,428
astrocytoma 2 | 1,146
colon cancer 2 | 1,478
hepatocellular carcinoma 2 | 547
interstitial cystitis 2 | 2,312
non primary Sjogren syndrome sicca 2 | 891
ovarian neoplasm 2 | 99
primary pancreatic ductal adenocarcinoma 2 | 1,109
progressive supranuclear palsy 2 | 676
pulmonary arterial hypertension 2 | 75
subependymal giant cell astrocytoma 2 | 2,287
Cerebellar Dysmetria 1 | 56
Esophagitis 1 | 35
Everted lower lip vermilion 1 | 54
Hypomagnesemia 1 | 12
Pain 1 | 103
Prominent lower lip 1 | 64

Tissue

Digestive Tract 17 | 17,369
Endocrine System 17 | 18,159
Female tissues 17 | 17,400
Liver and Pancreas 17 | 16,750
Male tissues 17 | 17,142
Respiratory system 17 | 16,393
Skin and soft tissues 17 | 17,230
Urinary Tract 17 | 16,678
Blood and immune system 16 | 16,909
Cardiovascular System 16 | 15,192
Nervous System 16 | 16,725

Target Family

Non-IDG 7 | 12,091
Enzyme 5 | 4,145
Epigenetic 2 | 242
GPCR 2 | 408
Transcription Factor 2 | 1,400

GWAS Trait

Coronary artery disease or lar... 18 | 18
Obesity-related traits 569 | 569
Schizophrenia 533 | 533
Breast cancer 492 | 492
Body mass index 379 | 379
Height 369 | 369
Coronary artery disease 367 | 367
Blood protein levels 351 | 351
Post bronchodilator FEV1-FVC r... 308 | 308
Mean corpuscular volume 283 | 283
Platelet count 275 | 275
Intelligence (multi-trait anal... 267 | 267
Mean platelet volume 253 | 253
IgG glycosylation 250 | 250
Mean corpuscular hemoglobin 238 | 238
Inflammatory bowel disease 235 | 235
Plateletcrit 227 | 227
Crohn's disease 215 | 215
Type 2 diabetes 210 | 210
Red blood cell count 191 | 191
Monocyte count 183 | 183
Red cell distribution width 182 | 182
Eosinophil counts 180 | 180
Neuroticism 180 | 180
Platelet distribution width 174 | 174
Monocyte percentage of white c... 173 | 173
Post bronchodilator FEV1 173 | 173
Sum eosinophil basophil counts 173 | 173
White blood cell count 172 | 172
3-hydroxy-1-methylpropylmercap... 166 | 166
Eosinophil percentage of granu... 163 | 163
Eosinophil percentage of white... 163 | 163
Reticulocyte fraction of red c... 163 | 163
Ulcerative colitis 163 | 163
Granulocyte percentage of myel... 162 | 162
Itch intensity from mosquito b... 162 | 162
Systemic lupus erythematosus 159 | 159
High light scatter reticulocyt... 158 | 158
Lymphocyte counts 158 | 158
Reticulocyte count 158 | 158
Blood metabolite levels 157 | 157
Neutrophil count 154 | 154
High light scatter reticulocyt... 153 | 153
Neutrophil percentage of granu... 153 | 153
3-hydroxypropylmercapturic aci... 150 | 150
Tonsillectomy 149 | 149
Diastolic blood pressure 144 | 144
Sum basophil neutrophil counts 140 | 140
Autism spectrum disorder or sc... 134 | 134
Myeloid white cell count 133 | 133
Granulocyte count 132 | 132
Sum neutrophil eosinophil coun... 129 | 129
Colorectal cancer 126 | 126
Alzheimer disease and age of o... 124 | 124
Multiple sclerosis 124 | 124
Cholesterol, total 123 | 123
Night sleep phenotypes 123 | 123
Lung cancer 122 | 122
Lymphocyte percentage of white... 122 | 122
Menarche (age at onset) 122 | 122
Neutrophil percentage of white... 121 | 121
Rheumatoid arthritis 121 | 121
Systolic blood pressure 120 | 120
Immature fraction of reticuloc... 118 | 118
Diisocyanate-induced asthma 116 | 116
HDL cholesterol 116 | 116
Allergic disease (asthma, hay ... 115 | 115
Educational attainment (years ... 114 | 114
Hematocrit 113 | 113
Hemoglobin concentration 112 | 112
LDL cholesterol 110 | 110
QT interval 110 | 110
Waist circumference adjusted f... 110 | 110
Mosquito bite size 107 | 107
Asthma 106 | 106
Lobe attachment (rater-scored ... 103 | 103
Peripheral arterial disease (t... 101 | 101
Pulse pressure 97 | 97
Bipolar disorder 94 | 94
Major depressive disorder 94 | 94
Prostate cancer 92 | 92
Parkinson's disease 90 | 90
Hip circumference adjusted for... 89 | 89
Metabolite levels 87 | 87
Triglycerides 87 | 87
Colonoscopy-negative controls ... 85 | 85
Mean corpuscular hemoglobin co... 85 | 85
Itch intensity from mosquito b... 84 | 84
Bipolar disorder and schizophr... 83 | 83
Resting heart rate 82 | 82
Macrophage inflammatory protei... 81 | 81
Migraine 81 | 81
Waist-to-hip ratio adjusted fo... 81 | 81
PR interval in Tripanosoma cru... 80 | 80
Cognitive performance 79 | 79
Glomerular filtration rate (cr... 78 | 78
Late-onset Alzheimer's disease 78 | 78
Waist circumference adjusted f... 75 | 75
Tuberculosis 73 | 73
Type 1 diabetes 73 | 73
Morning vs. evening chronotype 72 | 72

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Histone deacetylase 9 HDAC9 Tclin Epigenetic -2.27309 185.2 431
Cadherin EGF LAG seven-pass G-type receptor 2 CELSR2 Tbio GPCR -1.22995 16.7 139
Histo-blood group ABO system transferase ABO Tbio Enzyme 0.00000 0
Transcription factor 21 TCF21 Tbio Transcription Factor -1.80598 67.7 120
Phosphatidylethanolamine N-methyltransferase PEMT Tbio Enzyme -1.90213 89.9 149
Zinc finger protein ZPR1 ZPR1 Tbio Non-IDG -1.41153 28.2 201
BRCA1-associated protein BRAP Tbio Non-IDG -1.27527 19.9 113
Doublesex- and mab-3-related transcription factor A1 DMRTA1 Tbio Transcription Factor -2.56464 369.4 114
Apolipoprotein(a) LPA Tbio Enzyme -3.51111 3598.6 227
Metal transporter CNNM2 CNNM2 Tbio Non-IDG -1.19798 16.4 115