Development Level

Tbio 14 | 11,445
Tdark 5 | 6,588
Tchem 3 | 1,598
Tclin 1 | 613

Collection

Kinase: IDG Consortium (Target... 1 | 125

IMPC Phenotype

increased bone mineral content 3 | 108
preweaning lethality, complete... 3 | 979
decreased lymphocyte cell numb... 2 | 83
decreased total body fat amoun... 2 | 207
increased bone mineral density 2 | 72
increased lean body mass 2 | 172
small thymus 2 | 16
abnormal cecum morphology 1 | 7
abnormal clavicle morphology 1 | 6
abnormal coat-hair pigmentatio... 1 | 64
abnormal colon morphology 1 | 3
abnormal duodenum morphology 1 | 4
abnormal embryo size 1 | 220
abnormal epididymis morphology 1 | 42
abnormal eye morphology 1 | 68
abnormal eyelid morphology 1 | 7
abnormal femur morphology 1 | 14
abnormal fibula morphology 1 | 2
abnormal gait 1 | 69
abnormal heart morphology 1 | 162
abnormal heart shape 1 | 5
abnormal humerus morphology 1 | 11
abnormal jejunum morphology 1 | 1
abnormal joint morphology 1 | 23
abnormal locomotor behavior 1 | 24
abnormal mandible morphology 1 | 2
abnormal maxilla morphology 1 | 17
abnormal pancreas morphology 1 | 13
abnormal pelvic girdle bone mo... 1 | 12
abnormal radius morphology 1 | 8
abnormal rib morphology 1 | 10
abnormal snout morphology 1 | 23
abnormal tibia morphology 1 | 14
abnormal tooth morphology 1 | 24
abnormal ulna morphology 1 | 8
abnormal vertebrae morphology 1 | 18
abnormal zygomatic bone morpho... 1 | 3
absent pancreas 1 | 1
absent teeth 1 | 3
decreased basophil cell number 1 | 16
decreased body length 1 | 101
decreased circulating alkaline... 1 | 46
decreased circulating amylase ... 1 | 28
decreased circulating bilirubi... 1 | 19
decreased circulating magnesiu... 1 | 13
decreased eosinophil cell numb... 1 | 24
decreased fasted circulating g... 1 | 65
decreased lean body mass 1 | 135
decreased vertical activity 1 | 208
distended jejunum 1 | 1
enlarged adrenal glands 1 | 3
enlarged cecum 1 | 5
enlarged duodenum 1 | 1
enlarged epididymis 1 | 31
enlarged heart 1 | 210
enlarged ileum 1 | 1
female infertility 1 | 60
increased circulating HDL chol... 1 | 80
increased circulating aspartat... 1 | 15
increased circulating calcium ... 1 | 34
increased circulating choleste... 1 | 66
increased fasted circulating g... 1 | 76
increased mean corpuscular hem... 1 | 96
increased mean corpuscular vol... 1 | 92
increased monocyte cell number 1 | 63
increased neutrophil cell numb... 1 | 46
increased red blood cell distr... 1 | 34
increased spleen weight 1 | 10
megacolon 1 | 2
preweaning lethality, incomple... 1 | 499
short tibia 1 | 97
small pancreas 1 | 1
small seminal vesicle 1 | 10
small spleen 1 | 19
thrombocytopenia 1 | 56
urinary bladder obstruction 1 | 4

Disease

Corneal disease 21 | 31
Carcinoma 20 | 11,493
ovarian cancer 18 | 8,520
ependymoma 15 | 4,679
glioblastoma 14 | 5,792
osteosarcoma 13 | 7,950
lung cancer 12 | 4,740
medulloblastoma, large-cell 12 | 6,241
atypical teratoid / rhabdoid tumor 11 | 5,112
psoriasis 11 | 6,694
Astrocytoma, Pilocytic 10 | 3,081
Breast cancer 10 | 3,578
Keratoconus 10 | 113
intraductal papillary-mucinous neoplasm (IPMN) 9 | 3,291
pancreatic cancer 9 | 2,398
pituitary cancer 9 | 1,972
primitive neuroectodermal tumor 9 | 3,035
acute quadriplegic myopathy 8 | 1,158
invasive ductal carcinoma 8 | 2,951
malignant mesothelioma 8 | 3,232
Kidney cancer 7 | 2,613
adult high grade glioma 7 | 3,801
dermatomyositis 7 | 966
intraductal papillary-mucinous adenoma (IPMA) 7 | 2,955
Cancer 6 | 2,499
breast carcinoma 6 | 1,638
interstitial cystitis 6 | 2,312
intraductal papillary-mucinous carcinoma (IPMC) 6 | 2,989
lung adenocarcinoma 6 | 2,716
ulcerative colitis 6 | 1,819
Pick disease 5 | 1,894
autosomal dominant Emery-Dreifuss muscular dystrophy 5 | 510
group 4 medulloblastoma 5 | 1,855
non-small cell lung cancer 5 | 2,890
primary pancreatic ductal adenocarcinoma 5 | 1,109
subependymal giant cell astrocytoma 5 | 2,287
Atopic dermatitis 4 | 952
Kidney disease 4 | 430
Multiple myeloma 4 | 1,332
Rheumatoid arthritis 4 | 1,191
acute myeloid leukemia 4 | 783
cystic fibrosis 4 | 1,696
diabetes mellitus 4 | 1,728
gastric carcinoma 4 | 807
group 3 medulloblastoma 4 | 4,104
juvenile dermatomyositis 4 | 1,187
lung carcinoma 4 | 2,843
medulloblastoma 4 | 720
oligodendroglioma 4 | 2,850
tuberculosis 4 | 2,010
Autosomal recessive predisposition 3 | 1,442
Down syndrome 3 | 499
Duchenne muscular dystrophy 3 | 601
Glaucoma 3 | 239
Hypertensive disease 3 | 292
Increase in blood pressure 3 | 119
Myopia 3 | 176
Schizophrenia 3 | 1,160
Vascular disease 3 | 319
aldosterone-producing adenoma 3 | 665
astrocytic glioma 3 | 2,597
astrocytoma 3 | 1,146
ductal carcinoma in situ 3 | 1,745
esophageal adenocarcinoma 3 | 737
nasopharyngeal carcinoma 3 | 1,058
pancreatic ductal adenocarcinoma liver metastasis 3 | 1,962
urothelial carcinoma 3 | 318
Acquired metabolic disease 2 | 336
Acquired scoliosis 2 | 281
Amyotrophic lateral sclerosis 2 | 451
Becker muscular dystrophy 2 | 191
Bipolar Disorder 2 | 666
Craniofacial Abnormalities 2 | 151
Curvature of spine 2 | 282
Degenerative polyarthritis 2 | 115
Diarrhea 2 | 253
Ecchymosis 2 | 66
Endometriosis 2 | 540
Gaucher disease type 1 2 | 180
Hernia, Inguinal 2 | 89
Inflammatory bowel disease 2 | 151
Liver Cirrhosis 2 | 181
Liver Cirrhosis, Experimental 2 | 769
Liver cancer 2 | 604
Melanoma 2 | 711
Prostatic Neoplasms 2 | 495
Skin cancer 2 | 469
Umbilical hernia 2 | 93
Waldenstrons macroglobulinemia 2 | 765
X-linked cerebral adrenoleukodystrophy 2 | 116
active Crohn's disease 2 | 922
adrenocortical carcinoma 2 | 1,428
colon cancer 2 | 1,478
fibroadenoma 2 | 559
hepatocellular carcinoma 2 | 547
hereditary spastic paraplegia 2 | 318
pancreatic carcinoma 2 | 562
pediatric high grade glioma 2 | 1,064
sonic hedgehog group medulloblastoma 2 | 467
spina bifida 2 | 1,074

Tissue

Endocrine System 22 | 18,159
Female tissues 22 | 17,400
Male tissues 22 | 17,142
Nervous System 22 | 16,725
Blood and immune system 21 | 16,909
Digestive Tract 21 | 17,369
Liver and Pancreas 21 | 16,750
Respiratory system 21 | 16,393
Urinary Tract 21 | 16,678
Cardiovascular System 20 | 15,192
Skin and soft tissues 20 | 17,230

Target Family

Non-IDG 9 | 12,091
Enzyme 5 | 4,145
Transcription Factor 5 | 1,400
Kinase 2 | 634
GPCR 1 | 408
Nuclear Receptor 1 | 48

GWAS Trait

Corneal structure 23 | 23
Obesity-related traits 569 | 569
Schizophrenia 533 | 533
Breast cancer 492 | 492
Body mass index 379 | 379
Height 369 | 369
Coronary artery disease 367 | 367
Blood protein levels 351 | 351
Post bronchodilator FEV1-FVC r... 308 | 308
Mean corpuscular volume 283 | 283
Platelet count 275 | 275
Intelligence (multi-trait anal... 267 | 267
Mean platelet volume 253 | 253
IgG glycosylation 250 | 250
Mean corpuscular hemoglobin 238 | 238
Inflammatory bowel disease 235 | 235
Plateletcrit 227 | 227
Crohn's disease 215 | 215
Type 2 diabetes 210 | 210
Red blood cell count 191 | 191
Monocyte count 183 | 183
Red cell distribution width 182 | 182
Eosinophil counts 180 | 180
Neuroticism 180 | 180
Platelet distribution width 174 | 174
Monocyte percentage of white c... 173 | 173
Post bronchodilator FEV1 173 | 173
Sum eosinophil basophil counts 173 | 173
White blood cell count 172 | 172
3-hydroxy-1-methylpropylmercap... 166 | 166
Eosinophil percentage of granu... 163 | 163
Eosinophil percentage of white... 163 | 163
Reticulocyte fraction of red c... 163 | 163
Ulcerative colitis 163 | 163
Granulocyte percentage of myel... 162 | 162
Itch intensity from mosquito b... 162 | 162
Systemic lupus erythematosus 159 | 159
High light scatter reticulocyt... 158 | 158
Lymphocyte counts 158 | 158
Reticulocyte count 158 | 158
Blood metabolite levels 157 | 157
Neutrophil count 154 | 154
High light scatter reticulocyt... 153 | 153
Neutrophil percentage of granu... 153 | 153
3-hydroxypropylmercapturic aci... 150 | 150
Tonsillectomy 149 | 149
Diastolic blood pressure 144 | 144
Sum basophil neutrophil counts 140 | 140
Autism spectrum disorder or sc... 134 | 134
Myeloid white cell count 133 | 133
Granulocyte count 132 | 132
Sum neutrophil eosinophil coun... 129 | 129
Colorectal cancer 126 | 126
Alzheimer disease and age of o... 124 | 124
Multiple sclerosis 124 | 124
Cholesterol, total 123 | 123
Night sleep phenotypes 123 | 123
Lung cancer 122 | 122
Lymphocyte percentage of white... 122 | 122
Menarche (age at onset) 122 | 122
Neutrophil percentage of white... 121 | 121
Rheumatoid arthritis 121 | 121
Systolic blood pressure 120 | 120
Immature fraction of reticuloc... 118 | 118
Diisocyanate-induced asthma 116 | 116
HDL cholesterol 116 | 116
Allergic disease (asthma, hay ... 115 | 115
Educational attainment (years ... 114 | 114
Hematocrit 113 | 113
Hemoglobin concentration 112 | 112
LDL cholesterol 110 | 110
QT interval 110 | 110
Waist circumference adjusted f... 110 | 110
Mosquito bite size 107 | 107
Asthma 106 | 106
Lobe attachment (rater-scored ... 103 | 103
Peripheral arterial disease (t... 101 | 101
Pulse pressure 97 | 97
Bipolar disorder 94 | 94
Major depressive disorder 94 | 94
Prostate cancer 92 | 92
Parkinson's disease 90 | 90
Hip circumference adjusted for... 89 | 89
Metabolite levels 87 | 87
Triglycerides 87 | 87
Colonoscopy-negative controls ... 85 | 85
Mean corpuscular hemoglobin co... 85 | 85
Itch intensity from mosquito b... 84 | 84
Bipolar disorder and schizophr... 83 | 83
Resting heart rate 82 | 82
Macrophage inflammatory protei... 81 | 81
Migraine 81 | 81
Waist-to-hip ratio adjusted fo... 81 | 81
PR interval in Tripanosoma cru... 80 | 80
Cognitive performance 79 | 79
Glomerular filtration rate (cr... 78 | 78
Late-onset Alzheimer's disease 78 | 78
Waist circumference adjusted f... 75 | 75
Tuberculosis 73 | 73
Type 1 diabetes 73 | 73
Morning vs. evening chronotype 72 | 72

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
A disintegrin and metalloproteinase with thrombospondin motifs 6 ADAMTS6 Tdark Enzyme -0.67364 4.37 40
Chondroitin sulfate synthase 1 CHSY1 Tbio Enzyme -1.69082 48.5 101
AT-rich interactive domain-containing protein 5B ARID5B Tbio Transcription Factor -1.71561 54.6 97
Forkhead box protein O1 FOXO1 Tbio Transcription Factor -3.05358 1143.3 1478
Transmembrane protein 248 TMEM248 Tdark Non-IDG 0.00000 47
Mitogen-activated protein kinase kinase kinase 19 MAP3K19 Tchem Kinase 0.08 1.74 33
Fibronectin type III domain-containing protein 3B FNDC3B Tbio Non-IDG -1.38127 25.0 103
Class E basic helix-loop-helix protein 40 BHLHE40 Tbio Transcription Factor -1.77841 66.6 224
Leucine-rich repeat serine/threonine-protein kinase 1 LRRK1 Tbio Kinase -1.33128 18.1 134
Mineralocorticoid receptor NR3C2 Tclin Nuclear Receptor -3.08863 1005.8 203