Development Level

Tbio 5 | 11,445

IMPC Phenotype

decreased leukocyte cell numbe... 1 | 73
decreased total body fat amoun... 1 | 207
increased circulating chloride... 1 | 41
increased circulating sodium l... 1 | 71
preweaning lethality, complete... 1 | 979

Disease

osteosarcoma 5 | 7,950
Carcinoma 4 | 11,493
glioblastoma 4 | 5,792
medulloblastoma, large-cell 4 | 6,241
ovarian cancer 4 | 8,520
Breast cancer 3 | 3,578
Kidney cancer 3 | 2,613
astrocytic glioma 3 | 2,597
atypical teratoid / rhabdoid tumor 3 | 5,112
Autosomal recessive predisposition 2 | 1,442
Dull intelligence 2 | 645
Intellectual disability 2 | 1,016
Low intelligence 2 | 645
Mental Retardation 2 | 645
Mental deficiency 2 | 645
Poor school performance 2 | 645
Short stature 2 | 531
adult high grade glioma 2 | 3,801
ependymoma 2 | 4,679
group 3 medulloblastoma 2 | 4,104
group 4 medulloblastoma 2 | 1,855
lung carcinoma 2 | 2,843
non-small cell lung cancer 2 | 2,890
oligodendroglioma 2 | 2,850
Abnormality of the metaphyses 1 | 48
Absent mandible 1 | 6
Amyotrophic lateral sclerosis 1 | 451
Anteverted nostril 1 | 191
Aplasia/Hypoplasia of the mandible 1 | 3
Ataxia, Truncal 1 | 21
Atrophy of cerebellum 1 | 103
Autistic Disorder 1 | 364
Autosomal dominant Robinow syndrome 2 1 | 22
Bone pain 1 | 42
Bulbous nasal tip 1 | 48
Bulbous nose 1 | 48
Bushy eyebrows 1 | 49
Cerebellar degeneration 1 | 103
Cerebral atrophy 1 | 178
Cerebral palsy 1 | 40
Choanal Atresia 1 | 42
Chondrosarcoma 1 | 21
Cone-shaped epiphyses of phalanges 1 | 15
Cranial nerve palsies 1 | 11
Decreased projection of lower jaw 1 | 3
Deep philtrum 1 | 21
Deficiency of lower jaw 1 | 3
Degenerative brain disorder 1 | 100
Delayed bone age 1 | 136
Dental abnormalities 1 | 60
Depressed philtrum 1 | 21
Dysarthria 1 | 192
Eastern equine encephalitis 1 | 16
Exostosis 1 | 15
Extratemporal epilepsy 1 | 6
Failure to gain weight 1 | 365
Foot Deformities 1 | 30
Gaucher disease type 1 1 | 180
Hip joint varus deformity - observation 1 | 24
Hyperreflexia 1 | 209
Infratentorial atrophy 1 | 103
Intrahepatic cholestasis 1 | 20
Joint hyperflexibility 1 | 78
Juvenile astrocytoma 1 | 3
Knee joint valgus deformity 1 | 56
Langer-Giedion Syndrome 1 | 2
Long philtrum 1 | 137
Maffucci syndrome 1 | 6
Mandibular Retrusion 1 | 3
Measles 1 | 22
Micromelia 1 | 58
Multiple exostoses of long tubular bones 1 | 2
Muscle Weakness 1 | 170
Neurogenic Muscular Atrophy 1 | 139
Neurogenic muscle atrophy, especially in the lower limbs 1 | 139
Neuronal ceroid lipofuscinosis 1 1 | 15
Ollier disease 1 | 18
Pediatric failure to thrive 1 | 365
Potato nose 1 | 48
Prenatal onset 1 | 139
Prominent ear 1 | 56
Protruding ears 1 | 56
Redundant skin 1 | 28
Seizures 1 | 596
Short metacarpal 1 | 43
Short ulnae 1 | 24
Skeletal muscle atrophy 1 | 139
Sparse scalp hair 1 | 42
Strabismus 1 | 270
Supratentorial atrophy 1 | 94
Thin upper lip vermilion 1 | 67
Tooth Abnormalities 1 | 69
Trichorhinophalangeal syndrome type I 1 | 8
Trichorhinophalangeal syndrome type II 1 | 15
ULNAR HYPOPLASIA 1 | 24
Weight Gain 1 | 100
cystic fibrosis and chronic rhinosinusitis 1 | 214
facioscapulohumeral dystrophy 1 | 288
muscle degeneration 1 | 139
type II diabetes mellitus and post-ischemic heart failure 1 | 88

Tissue

Blood and immune system 5 | 16,909
Digestive Tract 5 | 17,369
Endocrine System 5 | 18,159
Female tissues 5 | 17,400
Liver and Pancreas 5 | 16,750
Male tissues 5 | 17,142
Nervous System 5 | 16,725
Respiratory system 5 | 16,393
Skin and soft tissues 5 | 17,230
Urinary Tract 5 | 16,678
Cardiovascular System 4 | 15,192

Target Family

Enzyme 2 | 4,145
Non-IDG 2 | 12,091
Transporter 1 | 473

GWAS Trait

Common carotid intima-media th... 5 | 5
Obesity-related traits 569 | 569
Schizophrenia 533 | 533
Breast cancer 492 | 492
Body mass index 379 | 379
Height 369 | 369
Coronary artery disease 367 | 367
Blood protein levels 351 | 351
Post bronchodilator FEV1-FVC r... 308 | 308
Mean corpuscular volume 283 | 283
Platelet count 275 | 275
Intelligence (multi-trait anal... 267 | 267
Mean platelet volume 253 | 253
IgG glycosylation 250 | 250
Mean corpuscular hemoglobin 238 | 238
Inflammatory bowel disease 235 | 235
Plateletcrit 227 | 227
Crohn's disease 215 | 215
Type 2 diabetes 210 | 210
Red blood cell count 191 | 191
Monocyte count 183 | 183
Red cell distribution width 182 | 182
Eosinophil counts 180 | 180
Neuroticism 180 | 180
Platelet distribution width 174 | 174
Monocyte percentage of white c... 173 | 173
Post bronchodilator FEV1 173 | 173
Sum eosinophil basophil counts 173 | 173
White blood cell count 172 | 172
3-hydroxy-1-methylpropylmercap... 166 | 166
Eosinophil percentage of granu... 163 | 163
Eosinophil percentage of white... 163 | 163
Reticulocyte fraction of red c... 163 | 163
Ulcerative colitis 163 | 163
Granulocyte percentage of myel... 162 | 162
Itch intensity from mosquito b... 162 | 162
Systemic lupus erythematosus 159 | 159
High light scatter reticulocyt... 158 | 158
Lymphocyte counts 158 | 158
Reticulocyte count 158 | 158
Blood metabolite levels 157 | 157
Neutrophil count 154 | 154
High light scatter reticulocyt... 153 | 153
Neutrophil percentage of granu... 153 | 153
3-hydroxypropylmercapturic aci... 150 | 150
Tonsillectomy 149 | 149
Diastolic blood pressure 144 | 144
Sum basophil neutrophil counts 140 | 140
Autism spectrum disorder or sc... 134 | 134
Myeloid white cell count 133 | 133
Granulocyte count 132 | 132
Sum neutrophil eosinophil coun... 129 | 129
Colorectal cancer 126 | 126
Alzheimer disease and age of o... 124 | 124
Multiple sclerosis 124 | 124
Cholesterol, total 123 | 123
Night sleep phenotypes 123 | 123
Lung cancer 122 | 122
Lymphocyte percentage of white... 122 | 122
Menarche (age at onset) 122 | 122
Neutrophil percentage of white... 121 | 121
Rheumatoid arthritis 121 | 121
Systolic blood pressure 120 | 120
Immature fraction of reticuloc... 118 | 118
Diisocyanate-induced asthma 116 | 116
HDL cholesterol 116 | 116
Allergic disease (asthma, hay ... 115 | 115
Educational attainment (years ... 114 | 114
Hematocrit 113 | 113
Hemoglobin concentration 112 | 112
LDL cholesterol 110 | 110
QT interval 110 | 110
Waist circumference adjusted f... 110 | 110
Mosquito bite size 107 | 107
Asthma 106 | 106
Lobe attachment (rater-scored ... 103 | 103
Peripheral arterial disease (t... 101 | 101
Pulse pressure 97 | 97
Bipolar disorder 94 | 94
Major depressive disorder 94 | 94
Prostate cancer 92 | 92
Parkinson's disease 90 | 90
Hip circumference adjusted for... 89 | 89
Metabolite levels 87 | 87
Triglycerides 87 | 87
Colonoscopy-negative controls ... 85 | 85
Mean corpuscular hemoglobin co... 85 | 85
Itch intensity from mosquito b... 84 | 84
Bipolar disorder and schizophr... 83 | 83
Resting heart rate 82 | 82
Macrophage inflammatory protei... 81 | 81
Migraine 81 | 81
Waist-to-hip ratio adjusted fo... 81 | 81
PR interval in Tripanosoma cru... 80 | 80
Cognitive performance 79 | 79
Glomerular filtration rate (cr... 78 | 78
Late-onset Alzheimer's disease 78 | 78
Waist circumference adjusted f... 75 | 75
Tuberculosis 73 | 73
Type 1 diabetes 73 | 73
Morning vs. evening chronotype 72 | 72

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Pre-mRNA-splicing factor SLU7 SLU7 Tbio Non-IDG -1.30438 19.4 221
Phospholipid-transporting ATPase IB ATP8A2 Tbio Transporter -1.19196 15.1 76
Sestrin-3 SESN3 Tbio Non-IDG -1.21917 15.5 148
Exostosin-1 EXT1 Tbio Enzyme -2.68804 491.2 178
Protein phosphatase 1 regulatory subunit 14C PPP1R14C Tbio Enzyme -1.22920 17.0 79