Development Level

Tbio 89 | 11,651
Tdark 25 | 6,593
Tchem 10 | 1,388
Tclin 2 | 612

Collection

RFA-RM-18-021 3 | 328
GPCR: IDG Consortium (Targets) 2 | 126
Ion Channel: IDG Consortium (T... 1 | 99

IMPC Phenotype

preweaning lethality, complete... 15 | 979
preweaning lethality, incomple... 7 | 499
abnormal behavior 5 | 298
decreased total body fat amoun... 4 | 207
abnormal bone structure 3 | 187
decreased body length 3 | 101
decreased body weight 3 | 161
decreased bone mineral content 3 | 151
decreased lean body mass 3 | 135
increased circulating HDL chol... 3 | 80
increased circulating choleste... 3 | 66
increased or absent threshold ... 3 | 101
increased total body fat amoun... 3 | 134
abnormal cranium morphology 2 | 36
abnormal embryo size 2 | 220
abnormal retina morphology 2 | 71
abnormal snout morphology 2 | 23
decreased bone mineral density 2 | 126
decreased circulating alanine ... 2 | 47
decreased circulating aspartat... 2 | 34
decreased fasted circulating g... 2 | 65
edema 2 | 59
embryonic lethality prior to o... 2 | 239
embryonic lethality prior to t... 2 | 278
hypoactivity 2 | 132
impaired glucose tolerance 2 | 75
improved glucose tolerance 2 | 79
increased circulating alkaline... 2 | 122
increased fasted circulating g... 2 | 76
increased grip strength 2 | 41
increased lean body mass 2 | 172
male infertility 2 | 123
prenatal lethality prior to he... 2 | 87
short tibia 2 | 97
abnormal craniofacial morpholo... 1 | 33
abnormal epididymis morphology 1 | 42
abnormal eyelid morphology 1 | 7
abnormal facial morphology 1 | 17
abnormal head shape 1 | 10
abnormal head size 1 | 6
abnormal heart morphology 1 | 162
abnormal incisor morphology 1 | 4
abnormal joint morphology 1 | 23
abnormal male genitalia morpho... 1 | 3
abnormal mandible morphology 1 | 2
abnormal skin coloration 1 | 25
abnormal skin condition 1 | 6
abnormal tail morphology 1 | 25
abnormal testis morphology 1 | 43
abnormal tooth morphology 1 | 24
abnormal urinary bladder morph... 1 | 11
abnormal vitreous body morphol... 1 | 10
abnormal vocalization 1 | 21
absent external male genitalia 1 | 1
absent pinna reflex 1 | 23
absent teeth 1 | 3
anophthalmia 1 | 33
cataract 1 | 92
cleft palate 1 | 8
decreased caudal vertebrae num... 1 | 53
decreased circulating LDL chol... 1 | 38
decreased circulating free fat... 1 | 31
decreased circulating insulin ... 1 | 76
decreased circulating phosphat... 1 | 27
decreased circulating potassiu... 1 | 20
decreased circulating serum al... 1 | 82
decreased circulating sodium l... 1 | 22
decreased grip strength 1 | 116
decreased heart left ventricle... 1 | 28
decreased heart weight 1 | 27
decreased mean corpuscular hem... 1 | 50
decreased mean corpuscular vol... 1 | 79
decreased prepulse inhibition 1 | 82
decreased startle reflex 1 | 75
enlarged epididymis 1 | 31
enlarged heart 1 | 210
facial cleft 1 | 3
increased blood urea nitrogen ... 1 | 48
increased body weight 1 | 25
increased bone mineral content 1 | 108
increased bone mineral density 1 | 72
increased circulating creatini... 1 | 38
increased circulating magnesiu... 1 | 10
increased circulating phosphat... 1 | 26
increased heart rate 1 | 23
increased heart rate variabili... 1 | 7
increased mean corpuscular hem... 1 | 96
limb grasping 1 | 41
oligodactyly 1 | 1
pallor 1 | 34
polydactyly 1 | 7
prolonged PQ interval 1 | 5
shortened PQ interval 1 | 7
small adrenal glands 1 | 16
small kidney 1 | 16
small testis 1 | 58

Disease

Carcinoma 85 | 11,493
ovarian cancer 78 | 8,520
osteosarcoma 70 | 7,950
medulloblastoma, large-cell 56 | 6,241
ependymoma 53 | 4,679
atypical teratoid / rhabdoid tumor 52 | 5,112
glioblastoma 52 | 5,792
psoriasis 49 | 6,694
Breast cancer 48 | 3,578
lung cancer 47 | 4,740
intraductal papillary-mucinous adenoma (IPMA) 42 | 2,955
intraductal papillary-mucinous neoplasm (IPMN) 41 | 3,291
adult high grade glioma 37 | 3,801
group 3 medulloblastoma 37 | 4,104
intraductal papillary-mucinous carcinoma (IPMC) 37 | 2,989
invasive ductal carcinoma 37 | 2,951
malignant mesothelioma 37 | 3,232
Kidney cancer 34 | 2,613
lung carcinoma 34 | 2,843
oligodendroglioma 34 | 2,850
primitive neuroectodermal tumor 32 | 3,035
Astrocytoma, Pilocytic 31 | 3,081
interstitial cystitis 30 | 2,312
subependymal giant cell astrocytoma 30 | 2,287
lung adenocarcinoma 28 | 2,716
astrocytic glioma 27 | 2,597
pancreatic cancer 27 | 2,398
Pick disease 26 | 1,894
cystic fibrosis 26 | 1,696
ulcerative colitis 26 | 1,819
ductal carcinoma in situ 24 | 1,745
group 4 medulloblastoma 24 | 1,855
non-small cell lung cancer 23 | 2,890
breast carcinoma 22 | 1,638
pituitary cancer 21 | 1,972
Cancer 19 | 2,499
primary pancreatic ductal adenocarcinoma 16 | 1,109
Colorectal Neoplasms 15 | 243
acute quadriplegic myopathy 15 | 1,158
astrocytoma 15 | 1,146
tuberculosis 15 | 2,010
gastric carcinoma 14 | 807
juvenile dermatomyositis 14 | 1,187
Rheumatoid arthritis 13 | 1,191
colon cancer 13 | 1,478
Duchenne muscular dystrophy 12 | 601
diabetes mellitus 12 | 1,728
Schizophrenia 11 | 1,160
autosomal dominant Emery-Dreifuss muscular dystrophy 11 | 510
esophageal adenocarcinoma 11 | 737
pediatric high grade glioma 11 | 1,064
spina bifida 11 | 1,074
Liver Cirrhosis, Experimental 10 | 769
Melanoma 10 | 711
medulloblastoma 10 | 720
Hypertension 9 | 396
Kidney disease 9 | 430
Liver cancer 9 | 604
Multiple myeloma 9 | 1,332
active Crohn's disease 9 | 922
cutaneous lupus erythematosus 9 | 1,057
dermatomyositis 9 | 966
nasopharyngeal carcinoma 9 | 1,058
progressive supranuclear palsy 9 | 676
Atopic dermatitis 8 | 952
Type 2 diabetes mellitus 8 | 272
pancreatic ductal adenocarcinoma liver metastasis 8 | 1,962
primary Sjogren syndrome 8 | 735
Attention deficit hyperactivity disorder 7 | 278
Breast Neoplasms 7 | 445
Congenital hypoplasia of penis 7 | 176
Hypertensive disease 7 | 292
Mammary Neoplasms 7 | 425
Obesity 7 | 678
Prostate cancer 7 | 175
Prostatic Neoplasms 7 | 495
Short stature 7 | 531
Skin cancer 7 | 469
active ulcerative colitis 7 | 764
adrenocortical carcinoma 7 | 1,428
non primary Sjogren syndrome sicca 7 | 891
Autosomal recessive predisposition 6 | 1,442
Bipolar Disorder 6 | 666
Chronic obstructive pulmonary disease 6 | 184
Cognitive delay 6 | 608
Crohn's disease 6 | 321
Endometrial cancer 6 | 311
Endometriosis 6 | 540
Epilepsy 6 | 792
Global developmental delay 6 | 608
Heart disease 6 | 306
Intellectual disability 6 | 1,016
Mental and motor retardation 6 | 608
Multiple Sclerosis 6 | 540
Osteoporosis 6 | 363
Stomach Neoplasms 6 | 300
acute myeloid leukemia 6 | 783
fibroadenoma 6 | 559
posterior fossa group B ependymoma 6 | 416
urothelial carcinoma 6 | 318

Tissue

Digestive Tract 120 | 17,369
Endocrine System 120 | 18,159
Skin and soft tissues 120 | 17,230
Female tissues 119 | 17,400
Liver and Pancreas 119 | 16,750
Male tissues 119 | 17,142
Nervous System 118 | 16,725
Urinary Tract 118 | 16,678
Blood and immune system 117 | 16,909
Respiratory system 117 | 16,393
Cardiovascular System 110 | 15,192

Target Family

Non-IDG 81 | 12,091
Enzyme 17 | 4,145
Transcription Factor 16 | 1,400
Ion Channel 3 | 344
Kinase 3 | 634
Transporter 3 | 473
GPCR 2 | 408
oGPCR 1 | 421

GWAS Trait

Colorectal cancer 126 | 126
Obesity-related traits 569 | 569
Schizophrenia 533 | 533
Breast cancer 492 | 492
Body mass index 379 | 379
Height 369 | 369
Coronary artery disease 367 | 367
Blood protein levels 351 | 351
Post bronchodilator FEV1-FVC r... 308 | 308
Mean corpuscular volume 283 | 283
Platelet count 275 | 275
Intelligence (multi-trait anal... 267 | 267
Mean platelet volume 253 | 253
IgG glycosylation 250 | 250
Mean corpuscular hemoglobin 238 | 238
Inflammatory bowel disease 235 | 235
Plateletcrit 227 | 227
Crohn's disease 215 | 215
Type 2 diabetes 210 | 210
Red blood cell count 191 | 191
Monocyte count 183 | 183
Red cell distribution width 182 | 182
Eosinophil counts 180 | 180
Neuroticism 180 | 180
Platelet distribution width 174 | 174
Monocyte percentage of white c... 173 | 173
Post bronchodilator FEV1 173 | 173
Sum eosinophil basophil counts 173 | 173
White blood cell count 172 | 172
3-hydroxy-1-methylpropylmercap... 166 | 166
Eosinophil percentage of granu... 163 | 163
Eosinophil percentage of white... 163 | 163
Reticulocyte fraction of red c... 163 | 163
Ulcerative colitis 163 | 163
Granulocyte percentage of myel... 162 | 162
Itch intensity from mosquito b... 162 | 162
Systemic lupus erythematosus 159 | 159
High light scatter reticulocyt... 158 | 158
Lymphocyte counts 158 | 158
Reticulocyte count 158 | 158
Blood metabolite levels 157 | 157
Neutrophil count 154 | 154
High light scatter reticulocyt... 153 | 153
Neutrophil percentage of granu... 153 | 153
3-hydroxypropylmercapturic aci... 150 | 150
Tonsillectomy 149 | 149
Diastolic blood pressure 144 | 144
Sum basophil neutrophil counts 140 | 140
Autism spectrum disorder or sc... 134 | 134
Myeloid white cell count 133 | 133
Granulocyte count 132 | 132
Sum neutrophil eosinophil coun... 129 | 129
Alzheimer disease and age of o... 124 | 124
Multiple sclerosis 124 | 124
Cholesterol, total 123 | 123
Night sleep phenotypes 123 | 123
Lung cancer 122 | 122
Lymphocyte percentage of white... 122 | 122
Menarche (age at onset) 122 | 122
Neutrophil percentage of white... 121 | 121
Rheumatoid arthritis 121 | 121
Systolic blood pressure 120 | 120
Immature fraction of reticuloc... 118 | 118
Diisocyanate-induced asthma 116 | 116
HDL cholesterol 116 | 116
Allergic disease (asthma, hay ... 115 | 115
Educational attainment (years ... 114 | 114
Hematocrit 113 | 113
Hemoglobin concentration 112 | 112
LDL cholesterol 110 | 110
QT interval 110 | 110
Waist circumference adjusted f... 110 | 110
Mosquito bite size 107 | 107
Asthma 106 | 106
Lobe attachment (rater-scored ... 103 | 103
Peripheral arterial disease (t... 101 | 101
Pulse pressure 97 | 97
Bipolar disorder 94 | 94
Major depressive disorder 94 | 94
Prostate cancer 92 | 92
Parkinson's disease 90 | 90
Hip circumference adjusted for... 89 | 89
Metabolite levels 87 | 87
Triglycerides 87 | 87
Colonoscopy-negative controls ... 85 | 85
Mean corpuscular hemoglobin co... 85 | 85
Itch intensity from mosquito b... 84 | 84
Bipolar disorder and schizophr... 83 | 83
Resting heart rate 82 | 82
Macrophage inflammatory protei... 81 | 81
Migraine 81 | 81
Waist-to-hip ratio adjusted fo... 81 | 81
PR interval in Tripanosoma cru... 80 | 80
Cognitive performance 79 | 79
Glomerular filtration rate (cr... 78 | 78
Late-onset Alzheimer's disease 78 | 78
Waist circumference adjusted f... 75 | 75
Tuberculosis 73 | 73
Type 1 diabetes 73 | 73
Morning vs. evening chronotype 72 | 72

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Tyrosine-protein kinase ZAP-70 ZAP70 Tchem Kinase -2.91589 798.2 1515
Eukaryotic translation initiation factor 4E transporter EIF4ENIF1 Tbio Non-IDG -1.60874 36.7 242
RNA binding protein fox-1 homolog 1 RBFOX1 Tbio Non-IDG -2.00815 99.2 207
Ras-related protein Rab-31 RAB31 Tbio Enzyme -1.12978 14.8 109
Programmed cell death protein 2-like PDCD2L Tbio Non-IDG -0.34430 2.55 146
Protein FAM49B FAM49B Tdark Non-IDG -1.38473 22.2 47
Transforming growth factor beta-1 TGFB1 Tchem Non-IDG -3.84680 5672.0 1222
WW domain-containing oxidoreductase WWOX Tbio Enzyme -3.61683 3311.4 251
Endoplasmic reticulum aminopeptidase 1 ERAP1 Tchem Enzyme -2.32434 221.0 216
RB-associated KRAB zinc finger protein RBAK Tbio Transcription Factor -0.57992 6.07 123