Development Level

Tbio 19 | 10,625
Tchem 7 | 1,890
Tdark 5 | 7,003

IMPC Term

preweaning lethality, complete... 4 | 633
abnormal behavior 2 | 226
decreased body weight 2 | 174
decreased total body fat amoun... 2 | 186
increased or absent threshold ... 2 | 128
prenatal lethality prior to he... 2 | 64
abnormal craniofacial morpholo... 1 | 12
abnormal cranium morphology 1 | 32
abnormal embryo size 1 | 112
abnormal epididymis morphology 1 | 31
abnormal eyelid morphology 1 | 6
abnormal facial morphology 1 | 9
abnormal head morphology 1 | 10
abnormal head shape 1 | 4
abnormal head size 1 | 1
abnormal rib morphology 1 | 28
abnormal skin condition 1 | 6
abnormal snout morphology 1 | 18
abnormal tail morphology 1 | 17
abnormal testis morphology 1 | 30
abnormal thoracic vertebrae mo... 1 | 16
absent teeth 1 | 4
anophthalmia 1 | 20
cleft palate 1 | 6
craniofacial phenotype 1 | 9
decreased alpha-beta T cell nu... 1 | 12
decreased body length 1 | 108
decreased bone mineral content 1 | 157
decreased circulating free fat... 1 | 39
decreased circulating fructosa... 1 | 31
decreased circulating insulin ... 1 | 75
decreased fasted circulating g... 1 | 49
decreased lean body mass 1 | 195
decreased leukocyte cell numbe... 1 | 54
decreased lumbar vertebrae num... 1 | 62
decreased rib number 1 | 59
decreased spleen weight 1 | 13
decreased threshold for audito... 1 | 32
embryonic lethality prior to o... 1 | 148
embryonic lethality prior to t... 1 | 187
enlarged epididymis 1 | 27
enlarged heart 1 | 111
facial cleft 1 | 3
impaired glucose tolerance 1 | 52
improved glucose tolerance 1 | 56
increased bone mineral content 1 | 92
increased exploration in new e... 1 | 56
increased gamma-delta T cell n... 1 | 16
increased grip strength 1 | 83
increased lean body mass 1 | 107
increased startle reflex 1 | 38
limb grasping 1 | 35
mydriasis 1 | 9
polydactyly 1 | 22
preweaning lethality, incomple... 1 | 260
short tibia 1 | 82
shortened RR interval 1 | 19
small adrenal glands 1 | 15

Disease

ovarian cancer 23 | 8,492
Colorectal Cancer 21 | 62
osteosarcoma 18 | 7,933
intraductal papillary-mucinous adenoma (IPMA) 16 | 2,956
intraductal papillary-mucinous carcinoma (IPMC) 15 | 2,988
intraductal papillary-mucinous neoplasm (IPMN) 15 | 3,289
lung cancer 15 | 4,473
invasive ductal carcinoma 14 | 2,950
malignant mesothelioma 14 | 3,163
medulloblastoma, large-cell 13 | 6,234
psoriasis 13 | 6,685
atypical teratoid / rhabdoid tumor 12 | 4,369
interstitial cystitis 12 | 2,299
lung carcinoma 12 | 2,844
Breast cancer 10 | 3,099
Carcinoma 10 | 2,147
cystic fibrosis 10 | 1,670
Colorectal Neoplasms 9 | 217
glioblastoma 9 | 5,572
pancreatic cancer 9 | 2,300
ulcerative colitis 9 | 2,087
gastric carcinoma 8 | 832
oligodendroglioma 8 | 2,849
pediatric high grade glioma 8 | 2,712
primitive neuroectodermal tumor 8 | 3,031
subependymal giant cell astrocytoma 8 | 2,287
Cancer 7 | 2,346
Pick disease 7 | 1,893
ductal carcinoma in situ 7 | 1,745
lung adenocarcinoma 7 | 2,714
non-small cell lung cancer 7 | 2,798
pilocytic astrocytoma 7 | 3,086
Kidney disease 6 | 397
astrocytic glioma 6 | 2,241
breast carcinoma 6 | 1,614
ependymoma 6 | 2,514
esophageal adenocarcinoma 6 | 737
group 3 medulloblastoma 6 | 2,254
group 4 medulloblastoma 6 | 1,875
primary pancreatic ductal adenocarcinoma 6 | 1,271
adult high grade glioma 5 | 2,148
astrocytoma 5 | 1,493
colon cancer 5 | 1,475
diabetes mellitus 5 | 1,663
juvenile dermatomyositis 5 | 1,189
pituitary cancer 5 | 1,972
posterior fossa group A ependymoma 5 | 1,511
progressive supranuclear palsy 5 | 674
Atopic dermatitis 4 | 944
Duchenne muscular dystrophy 4 | 602
Hypertension 4 | 293
Multiple myeloma 4 | 1,328
Prostatic Neoplasms 4 | 471
acute quadriplegic myopathy 4 | 1,157
atypical teratoid/rhabdoid tumor 4 | 1,095
glioblastoma multiforme 4 | 347
posterior fossa group B ependymoma 4 | 1,530
Alzheimer's disease 3 | 644
Down syndrome 3 | 548
Mammary Neoplasms 3 | 410
Prostate cancer 3 | 172
Stomach Neoplasms 3 | 282
active ulcerative colitis 3 | 477
autosomal dominant Emery-Dreifuss muscular dystrophy 3 | 499
cutaneous lupus erythematosus 3 | 1,056
dermatomyositis 3 | 967
fibroadenoma 3 | 557
interstitial lung disease 3 | 292
nasopharyngeal carcinoma 3 | 1,056
non primary Sjogren syndrome sicca 3 | 840
sonic hedgehog group medulloblastoma 3 | 1,482
spina bifida 3 | 1,064
tuberculosis 3 | 1,563
Acquired metabolic disease 2 | 267
Adenocarcinoma 2 | 115
Amphetamine-Related Disorders 2 | 74
Amyotrophic Lateral Sclerosis 2 | 432
Cardiovascular system disease 2 | 194
Celiac disease 2 | 112
Colonic Neoplasms 2 | 126
Coronary artery disease 2 | 240
Diabetes Mellitus, Insulin-Dependent 2 | 77
Diabetes Mellitus, Non-Insulin-Dependent 2 | 161
Endometriosis 2 | 535
Heart disease 2 | 279
Hypertensive disease 2 | 193
Inflammatory bowel disease 2 | 142
Melanoma 2 | 261
Myocardial Infarction 2 | 126
Nerve Degeneration 2 | 73
Neurodegenerative disease 2 | 383
Peripheral vascular disease 2 | 90
Pulmonary Fibrosis 2 | 66
Rheumatoid Arthritis 2 | 1,171
Substance-Related Disorders 2 | 114
active Crohn's disease 2 | 918
aldosterone-producing adenoma 2 | 664
ovarian neoplasm 2 | 97
pancreatic ductal adenocarcinoma liver metastasis 2 | 1,795
tuberculosis and treatment for 6 months 2 | 686

Tissue

Blood and immune system 30 | 17,995
Cardiovascular System 30 | 17,958
Digestive Tract 30 | 18,473
Endocrine System 30 | 18,512
Female tissues 30 | 18,647
Liver and Pancreas 30 | 18,136
Male tissues 30 | 17,969
Nervous System 30 | 18,561
Respiratory system 30 | 17,484
Skin and soft tissues 30 | 18,115
Urinary Tract 30 | 18,444

Target Family

Non-IDG 21 | 11,969
Transcription Factor 5 | 1,400
Enzyme 3 | 4,146
Kinase 1 | 634
Transporter 1 | 473

GWAS Trait

Colorectal cancer 31 | 31
Obesity-related traits 380 | 380
Schizophrenia 334 | 334
Height 250 | 250
Post bronchodilator FEV1/FVC r... 192 | 192
Body mass index 180 | 180
IgG glycosylation 162 | 162
Inflammatory bowel disease 117 | 117
Post bronchodilator FEV1 112 | 112
Crohn's disease 110 | 110
Blood metabolite levels 103 | 103
Type 2 diabetes 94 | 94
3-hydroxy-1-methylpropylmercap... 93 | 93
3-hydroxypropylmercapturic aci... 92 | 92
Ulcerative colitis 89 | 89
Platelet count 79 | 79
Systemic lupus erythematosus 78 | 78
HDL cholesterol 76 | 76
Rheumatoid arthritis 74 | 74
Cholesterol, total 73 | 73
Menarche (age at onset) 73 | 73
Diisocyanate-induced asthma 72 | 72
Multiple sclerosis 68 | 68
LDL cholesterol 67 | 67
QT interval 58 | 58
Metabolite levels 55 | 55
Atopic dermatitis 54 | 54
Bipolar disorder and schizophr... 54 | 54
Breast cancer 54 | 54
Prostate cancer 54 | 54
Triglycerides 53 | 53
Bipolar disorder 52 | 52
HIV-1 control 50 | 50
Post bronchodilator FEV1/FVC r... 50 | 50
HIV-1 viral setpoint 49 | 49
Cognitive performance 48 | 48
Amyotrophic lateral sclerosis ... 46 | 46
Bone mineral density 46 | 46
Clozapine-induced agranulocyto... 46 | 46
Attention deficit hyperactivit... 44 | 44
Blood pressure 44 | 44
Coronary heart disease 43 | 43
Glomerular filtration rate (cr... 43 | 43
Parkinson's disease 43 | 43
Type 1 diabetes 42 | 42
PR interval in Tripanosoma cru... 40 | 40
Post bronchodilator FEV1 in CO... 39 | 39
Alzheimer's disease (cognitive... 38 | 38
Educational attainment 38 | 38
Pulmonary function 38 | 38
Diffuse large B cell lymphoma 37 | 37
Inflammatory skin disease 37 | 37
Beta-2 microglubulin plasma le... 36 | 36
Glucose homeostasis traits 36 | 36
Urate levels 36 | 36
Blood metabolite ratios 35 | 35
Psoriasis 35 | 35
Autism spectrum disorder, atte... 34 | 34
Migraine 33 | 33
Coronary artery disease 32 | 32
Metabolic traits 32 | 32
Waist-to-hip ratio adjusted fo... 32 | 32
Cognitive function 31 | 31
Amyotrophic lateral sclerosis 30 | 30
Myopia (pathological) 30 | 30
Obesity 30 | 30
Response to amphetamines 30 | 30
Systolic blood pressure 30 | 30
Alzheimer's disease (late onse... 29 | 29
Celiac disease 29 | 29
Phospholipid levels (plasma) 29 | 29
Red blood cell traits 29 | 29
Advanced age-related macular d... 28 | 28
Dental caries 28 | 28
Fibrinogen levels 28 | 28
Parental extreme longevity (95... 28 | 28
Pulmonary function (interactio... 28 | 28
Asthma 27 | 27
Cognitive decline rate in late... 27 | 27
Glomerular filtration rate in ... 27 | 27
Longevity 27 | 27
Mean platelet volume 27 | 27
Chronic kidney disease 26 | 26
Diabetic kidney disease 26 | 26
Diastolic blood pressure 26 | 26
Coronary artery calcification 25 | 25
Metabolic syndrome 25 | 25
Pancreatic cancer 25 | 25
Protein quantitative trait loc... 25 | 25
Hypertension 24 | 24
Migraine - clinic-based 24 | 24
Parental longevity (combined p... 24 | 24
Primary biliary cirrhosis 24 | 24
Thiazide-induced adverse metab... 24 | 24
Menopause (age at onset) 23 | 23
Response to antipsychotic trea... 23 | 23
Age-related macular degenerati... 22 | 22
Immune response to smallpox va... 22 | 22
Mild influenza (H1N1) infectio... 22 | 22
Sudden cardiac arrest 22 | 22

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
LIM domain and actin-binding protein 1 LIMA1 Tbio Non-IDG -1.19919 22.9 167
Nucleoredoxin NXN Tbio Non-IDG -2.51638 323.4 88
CDK5 and ABL1 enzyme substrate 2 CABLES2 Tdark Non-IDG 0.08 0.95 67
Discoidin, CUB and LCCL domain-containing protein 1 DCBLD1 Tdark Non-IDG 0.21 0.33 15
Laminin subunit alpha-5 LAMA5 Tchem Non-IDG -1.35225 24.5 192
Laminin subunit gamma-1 LAMC1 Tchem Non-IDG -1.77441 53.6 239
T-box transcription factor TBX3 TBX3 Tbio Transcription Factor -2.39370 254.0 309
Rhophilin-2 RHPN2 Tbio Non-IDG -0.98570 10.4 100
Mothers against decapentaplegic homolog 7 SMAD7 Tbio Transcription Factor -2.77330 485.2 380
Heat shock 70 kDa protein 12A HSPA12A Tbio Non-IDG -0.30494 2.53 57