Development Level

Tbio 49 | 11,445
Tdark 20 | 6,588
Tclin 6 | 613
Tchem 4 | 1,598

Collection

Ion Channel: IDG Consortium (T... 1 | 99
Kinase: IDG Consortium (Target... 1 | 125

IMPC Phenotype

decreased bone mineral density 5 | 126
decreased bone mineral content 4 | 151
preweaning lethality, incomple... 4 | 499
abnormal behavior 3 | 298
abnormal bone structure 3 | 187
hyperactivity 3 | 148
increased body weight 3 | 25
increased circulating alkaline... 3 | 122
increased startle reflex 3 | 112
abnormal heart morphology 2 | 162
abnormal retina morphology 2 | 71
decreased body length 2 | 101
decreased circulating insulin ... 2 | 76
decreased vertical activity 2 | 208
embryonic lethality prior to o... 2 | 239
preweaning lethality, complete... 2 | 979
abnormal allantois morphology 1 | 8
abnormal behavioral response t... 1 | 66
abnormal coat- hair morphology 1 | 19
abnormal neural tube closure 1 | 46
abnormal neural tube morpholog... 1 | 12
abnormal retinal blood vessel ... 1 | 26
abnormal sleep behavior 1 | 70
abnormal spine curvature 1 | 9
abnormal spleen morphology 1 | 55
abnormal urinary bladder morph... 1 | 11
absent startle reflex 1 | 24
decreased IgG1 level 1 | 8
decreased KLRG1+ CD8 alpha bet... 1 | 2
decreased body weight 1 | 161
decreased caudal vertebrae num... 1 | 53
decreased circulating creatini... 1 | 39
decreased circulating serum al... 1 | 82
decreased circulating triglyce... 1 | 79
decreased lean body mass 1 | 135
decreased mean corpuscular hem... 1 | 50
decreased mean corpuscular hem... 1 | 31
decreased prepulse inhibition 1 | 82
decreased startle reflex 1 | 75
decreased total body fat amoun... 1 | 207
embryonic lethality prior to t... 1 | 278
enlarged heart 1 | 210
hypoactivity 1 | 132
impaired pupillary reflex 1 | 26
improved glucose tolerance 1 | 79
increased blood urea nitrogen ... 1 | 48
increased bone mineral content 1 | 108
increased circulating glycerol... 1 | 9
increased circulating sodium l... 1 | 71
increased or absent threshold ... 1 | 101
increased prepulse inhibition 1 | 32
increased total body fat amoun... 1 | 134
long tibia 1 | 25
mydriasis 1 | 6

Disease

Carcinoma 61 | 11,493
ovarian cancer 46 | 8,520
atypical teratoid / rhabdoid tumor 42 | 5,112
medulloblastoma, large-cell 40 | 6,241
glioblastoma 38 | 5,792
group 3 medulloblastoma 34 | 4,104
ependymoma 32 | 4,679
osteosarcoma 32 | 7,950
adult high grade glioma 30 | 3,801
Astrocytoma, Pilocytic 28 | 3,081
Kidney cancer 28 | 2,613
oligodendroglioma 28 | 2,850
psoriasis 27 | 6,694
astrocytic glioma 25 | 2,597
primitive neuroectodermal tumor 25 | 3,035
Breast cancer 24 | 3,578
lung carcinoma 24 | 2,843
lung cancer 23 | 4,740
intraductal papillary-mucinous carcinoma (IPMC) 21 | 2,989
cystic fibrosis 19 | 1,696
Pick disease 17 | 1,894
intraductal papillary-mucinous adenoma (IPMA) 17 | 2,955
intraductal papillary-mucinous neoplasm (IPMN) 16 | 3,291
invasive ductal carcinoma 16 | 2,951
lung adenocarcinoma 16 | 2,716
malignant mesothelioma 15 | 3,232
non-small cell lung cancer 15 | 2,890
interstitial cystitis 13 | 2,312
pancreatic cancer 13 | 2,398
pituitary cancer 13 | 1,972
group 4 medulloblastoma 12 | 1,855
subependymal giant cell astrocytoma 12 | 2,287
tuberculosis 12 | 2,010
ulcerative colitis 12 | 1,819
colon cancer 11 | 1,478
ductal carcinoma in situ 11 | 1,745
Liver cancer 10 | 604
adrenocortical carcinoma 10 | 1,428
Schizophrenia 9 | 1,160
Bipolar Disorder 8 | 666
Melanoma 8 | 711
active Crohn's disease 8 | 922
aldosterone-producing adenoma 8 | 665
pancreatic ductal adenocarcinoma liver metastasis 8 | 1,962
Autistic Disorder 7 | 364
Cancer 7 | 2,499
Down syndrome 7 | 499
Parkinson's disease 7 | 392
Rheumatoid arthritis 7 | 1,191
Skin cancer 7 | 469
active ulcerative colitis 7 | 764
astrocytoma 7 | 1,146
non primary Sjogren syndrome sicca 7 | 891
Multiple myeloma 6 | 1,332
breast carcinoma 6 | 1,638
hereditary spastic paraplegia 6 | 318
pediatric high grade glioma 6 | 1,064
Alcoholic Intoxication, Chronic 5 | 289
Alzheimer's disease 5 | 658
Amyotrophic lateral sclerosis 5 | 451
Atopic dermatitis 5 | 952
Substance-Related Disorders 5 | 115
Waldenstrons macroglobulinemia 5 | 765
acute myeloid leukemia 5 | 783
acute quadriplegic myopathy 5 | 1,158
diabetes mellitus 5 | 1,728
nephrosclerosis 5 | 333
primary Sjogren syndrome 5 | 735
spina bifida 5 | 1,074
Acquired metabolic disease 4 | 336
Attention deficit hyperactivity disorder 4 | 278
Endometrial cancer 4 | 311
Epilepsy 4 | 792
Mental Depression 4 | 333
Multiple Sclerosis 4 | 540
gastric carcinoma 4 | 807
hepatocellular carcinoma 4 | 547
juvenile dermatomyositis 4 | 1,187
nasopharyngeal carcinoma 4 | 1,058
non-small cell lung carcinoma 4 | 317
Autism spectrum disorder 3 | 101
Autosomal recessive predisposition 3 | 1,442
Cleft Lip 3 | 141
Cleft Palate 3 | 271
Depressive disorder 3 | 409
Duchenne muscular dystrophy 3 | 601
Hyperreflexia 3 | 209
Liver Cirrhosis 3 | 181
Liver Cirrhosis, Experimental 3 | 769
Major Depressive Disorder 3 | 301
Type 2 diabetes mellitus 3 | 272
cutaneous lupus erythematosus 3 | 1,057
dermatomyositis 3 | 966
head and neck cancer 3 | 271
medulloblastoma 3 | 720
mucosa-associated lymphoid tissue lymphoma 3 | 484
posterior fossa group B ependymoma 3 | 416
progressive supranuclear palsy 3 | 676
substance-related disorder 3 | 162
urothelial carcinoma 3 | 318

Tissue

Endocrine System 74 | 18,159
Nervous System 72 | 16,725
Skin and soft tissues 71 | 17,230
Digestive Tract 70 | 17,369
Female tissues 69 | 17,400
Liver and Pancreas 69 | 16,750
Urinary Tract 68 | 16,678
Male tissues 67 | 17,142
Blood and immune system 66 | 16,909
Respiratory system 64 | 16,393
Cardiovascular System 62 | 15,192

Target Family

Non-IDG 46 | 12,091
Enzyme 14 | 4,145
Transcription Factor 7 | 1,400
Ion Channel 6 | 344
Kinase 3 | 634
Transporter 2 | 473
TF/Epigenetic 1 | 38

GWAS Trait

Cognitive performance 79 | 79
Obesity-related traits 569 | 569
Schizophrenia 533 | 533
Breast cancer 492 | 492
Body mass index 379 | 379
Height 369 | 369
Coronary artery disease 367 | 367
Blood protein levels 351 | 351
Post bronchodilator FEV1-FVC r... 308 | 308
Mean corpuscular volume 283 | 283
Platelet count 275 | 275
Intelligence (multi-trait anal... 267 | 267
Mean platelet volume 253 | 253
IgG glycosylation 250 | 250
Mean corpuscular hemoglobin 238 | 238
Inflammatory bowel disease 235 | 235
Plateletcrit 227 | 227
Crohn's disease 215 | 215
Type 2 diabetes 210 | 210
Red blood cell count 191 | 191
Monocyte count 183 | 183
Red cell distribution width 182 | 182
Eosinophil counts 180 | 180
Neuroticism 180 | 180
Platelet distribution width 174 | 174
Monocyte percentage of white c... 173 | 173
Post bronchodilator FEV1 173 | 173
Sum eosinophil basophil counts 173 | 173
White blood cell count 172 | 172
3-hydroxy-1-methylpropylmercap... 166 | 166
Eosinophil percentage of granu... 163 | 163
Eosinophil percentage of white... 163 | 163
Reticulocyte fraction of red c... 163 | 163
Ulcerative colitis 163 | 163
Granulocyte percentage of myel... 162 | 162
Itch intensity from mosquito b... 162 | 162
Systemic lupus erythematosus 159 | 159
High light scatter reticulocyt... 158 | 158
Lymphocyte counts 158 | 158
Reticulocyte count 158 | 158
Blood metabolite levels 157 | 157
Neutrophil count 154 | 154
High light scatter reticulocyt... 153 | 153
Neutrophil percentage of granu... 153 | 153
3-hydroxypropylmercapturic aci... 150 | 150
Tonsillectomy 149 | 149
Diastolic blood pressure 144 | 144
Sum basophil neutrophil counts 140 | 140
Autism spectrum disorder or sc... 134 | 134
Myeloid white cell count 133 | 133
Granulocyte count 132 | 132
Sum neutrophil eosinophil coun... 129 | 129
Colorectal cancer 126 | 126
Alzheimer disease and age of o... 124 | 124
Multiple sclerosis 124 | 124
Cholesterol, total 123 | 123
Night sleep phenotypes 123 | 123
Lung cancer 122 | 122
Lymphocyte percentage of white... 122 | 122
Menarche (age at onset) 122 | 122
Neutrophil percentage of white... 121 | 121
Rheumatoid arthritis 121 | 121
Systolic blood pressure 120 | 120
Immature fraction of reticuloc... 118 | 118
Diisocyanate-induced asthma 116 | 116
HDL cholesterol 116 | 116
Allergic disease (asthma, hay ... 115 | 115
Educational attainment (years ... 114 | 114
Hematocrit 113 | 113
Hemoglobin concentration 112 | 112
LDL cholesterol 110 | 110
QT interval 110 | 110
Waist circumference adjusted f... 110 | 110
Mosquito bite size 107 | 107
Asthma 106 | 106
Lobe attachment (rater-scored ... 103 | 103
Peripheral arterial disease (t... 101 | 101
Pulse pressure 97 | 97
Bipolar disorder 94 | 94
Major depressive disorder 94 | 94
Prostate cancer 92 | 92
Parkinson's disease 90 | 90
Hip circumference adjusted for... 89 | 89
Metabolite levels 87 | 87
Triglycerides 87 | 87
Colonoscopy-negative controls ... 85 | 85
Mean corpuscular hemoglobin co... 85 | 85
Itch intensity from mosquito b... 84 | 84
Bipolar disorder and schizophr... 83 | 83
Resting heart rate 82 | 82
Macrophage inflammatory protei... 81 | 81
Migraine 81 | 81
Waist-to-hip ratio adjusted fo... 81 | 81
PR interval in Tripanosoma cru... 80 | 80
Glomerular filtration rate (cr... 78 | 78
Late-onset Alzheimer's disease 78 | 78
Waist circumference adjusted f... 75 | 75
Tuberculosis 73 | 73
Type 1 diabetes 73 | 73
Morning vs. evening chronotype 72 | 72

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Atlastin-1 ATL1 Tbio Non-IDG -2.07795 119.7 164
CUB and sushi domain-containing protein 1 CSMD1 Tbio Non-IDG -1.68684 47.7 0
Neurexin-3 NRXN3 Tbio Non-IDG -1.34072 34.8 172
Mitogen-activated protein kinase kinase kinase kinase 5 MAP4K5 Tchem Kinase -1.76819 60.5 0
Acetyl-coenzyme A synthetase 2-like, mitochondrial ACSS1 Tbio Enzyme -1.48800 26.8 73
Sodium/potassium/calcium exchanger 2 SLC24A2 Tbio Transporter -1.39605 25.7 32
Gamma-aminobutyric acid receptor subunit beta-3 GABRB3 Tclin Ion Channel -2.13205 136.0 202
Transcription regulator protein BACH2 BACH2 Tbio Transcription Factor -1.90906 89.8 184
Thymocyte selection-associated high mobility group box protein TOX TOX Tbio Transcription Factor -2.98637 953.0 77
Myelin-associated oligodendrocyte basic protein MOBP Tbio Non-IDG -1.36705 23.4 133