Development Level

Tbio 7 | 11,445
Tclin 4 | 613

Collection

Ion Channel: IDG Consortium (T... 1 | 99

IMPC Phenotype

preweaning lethality, complete... 2 | 979
abnormal behavior 1 | 298
abnormal pericardium morpholog... 1 | 26
abnormal tooth morphology 1 | 24
absent startle reflex 1 | 24
cataract 1 | 92
decreased circulating glucose ... 1 | 126
decreased circulating serum al... 1 | 82
decreased circulating sodium l... 1 | 22
decreased erythrocyte cell num... 1 | 62
embryonic lethality prior to t... 1 | 278
hyperactivity 1 | 148
increased circulating LDL chol... 1 | 13
increased circulating alkaline... 1 | 122
increased circulating bilirubi... 1 | 16
increased circulating choleste... 1 | 66
increased circulating free fat... 1 | 20
increased circulating triglyce... 1 | 42
increased mean corpuscular hem... 1 | 36
increased total body fat amoun... 1 | 134

Disease

Carcinoma 8 | 11,493
medulloblastoma, large-cell 7 | 6,241
osteosarcoma 7 | 7,950
ependymoma 6 | 4,679
glioblastoma 6 | 5,792
ovarian cancer 6 | 8,520
psoriasis 6 | 6,694
Kidney cancer 5 | 2,613
astrocytic glioma 5 | 2,597
lung cancer 5 | 4,740
Autosomal recessive predisposition 4 | 1,442
Breast cancer 4 | 3,578
adult high grade glioma 4 | 3,801
atypical teratoid / rhabdoid tumor 4 | 5,112
group 3 medulloblastoma 4 | 4,104
intraductal papillary-mucinous carcinoma (IPMC) 4 | 2,989
oligodendroglioma 4 | 2,850
Alzheimer's disease 3 | 658
Cancer 3 | 2,499
Cardiovascular system disease 3 | 246
Multiple Sclerosis 3 | 540
Schizophrenia 3 | 1,160
Skin cancer 3 | 469
cystic fibrosis 3 | 1,696
intraductal papillary-mucinous adenoma (IPMA) 3 | 2,955
intraductal papillary-mucinous neoplasm (IPMN) 3 | 3,291
lung carcinoma 3 | 2,843
pancreatic cancer 3 | 2,398
Atopic dermatitis 2 | 952
Bipolar Disorder 2 | 666
Coronary Disease 2 | 25
Coronary heart disease 2 | 16
Crohn's disease 2 | 321
Down syndrome 2 | 499
Dyslipidemias 2 | 27
General anesthesia 2 | 53
Macular degeneration 2 | 65
Melanoma 2 | 711
Multiple, subcutaneous nodules 2 | 53
Subcutaneous nodule 2 | 53
acute quadriplegic myopathy 2 | 1,158
adrenocortical carcinoma 2 | 1,428
diabetes mellitus 2 | 1,728
gastric carcinoma 2 | 807
interstitial cystitis 2 | 2,312
invasive ductal carcinoma 2 | 2,951
juvenile dermatomyositis 2 | 1,187
malignant mesothelioma 2 | 3,232
pancreatic ductal adenocarcinoma liver metastasis 2 | 1,962
pituitary cancer 2 | 1,972
primitive neuroectodermal tumor 2 | 3,035
ulcerative colitis 2 | 1,819
Absent axillary hair 1 | 5
Alcohol abuse 1 | 50
Amyloidosis 1 | 67
Benzodiazepine Induced Sedation 1 | 8
Benzodiazepine Maintained Anesthesia 1 | 8
Benzodiazepine Toxicity 1 | 8
Blepharitis 1 | 23
Bronchiectasis 1 | 64
Carotid Artery Diseases 1 | 11
Carotid stenosis 1 | 5
Cellulitis of eyelid 1 | 17
Congenital arteriovenous malformation 1 | 8
Delirium 1 | 10
Diabetic retinopathy 1 | 56
Drug-induced depressive state 1 | 14
Edema 1 | 81
Emphysema 1 | 12
Epilepsy, Temporal Lobe 1 | 23
Exaggerated acoustic startle response 1 | 8
Exaggerated startle response 1 | 8
Familial hyperlipidemia 1 | 6
Hemangiosarcoma 1 | 18
Hepatitis 1 | 67
Hepatolenticular Degeneration 1 | 24
Hereditary Hyperexplexia 1 | 4
Hypercholesterolemia, Familial 1 | 23
Hyperekplexia 1 | 16
Hyperekplexia, Hereditary 1 1 | 4
Hyperexplexia 1 | 8
Hyperexplexia hereditary 1 | 4
Hyperglycemia 1 | 137
Hyperlipoproteinemia Type II 1 | 12
Increased startle response 1 | 8
Insomnia 1 | 20
Intestinal volvulus 1 | 8
Liver Neoplasms, Experimental 1 | 59
Long tract signs 1 | 3
Lysosomal storage disease 1 | 10
Macular Degeneration, Age-Related, 1 1 | 9
Neurofibrillary degeneration (morphologic abnormality) 1 | 9
Pathological accumulation of air in tissues 1 | 10
Petechiae 1 | 13
Pneumothorax 1 | 23
Renal glomerular disease 1 | 12
Retinopathy of prematurity 1 | 22
Sedation as Adjunct to Anesthesia 1 | 15
Sinusitis 1 | 65
Steatohepatitis 1 | 44

Tissue

Female tissues 11 | 17,400
Digestive Tract 10 | 17,369
Endocrine System 10 | 18,159
Skin and soft tissues 10 | 17,230
Cardiovascular System 9 | 15,192
Liver and Pancreas 9 | 16,750
Male tissues 9 | 17,142
Nervous System 9 | 16,725
Respiratory system 9 | 16,393
Urinary Tract 9 | 16,678
Blood and immune system 7 | 16,909

Target Family

Non-IDG 6 | 12,091
Ion Channel 2 | 344
Enzyme 1 | 4,145
Kinase 1 | 634
Transporter 1 | 473

GWAS Trait

Cognitive decline (age-related... 11 | 11
Obesity-related traits 569 | 569
Schizophrenia 533 | 533
Breast cancer 492 | 492
Body mass index 379 | 379
Height 369 | 369
Coronary artery disease 367 | 367
Blood protein levels 351 | 351
Post bronchodilator FEV1-FVC r... 308 | 308
Mean corpuscular volume 283 | 283
Platelet count 275 | 275
Intelligence (multi-trait anal... 267 | 267
Mean platelet volume 253 | 253
IgG glycosylation 250 | 250
Mean corpuscular hemoglobin 238 | 238
Inflammatory bowel disease 235 | 235
Plateletcrit 227 | 227
Crohn's disease 215 | 215
Type 2 diabetes 210 | 210
Red blood cell count 191 | 191
Monocyte count 183 | 183
Red cell distribution width 182 | 182
Eosinophil counts 180 | 180
Neuroticism 180 | 180
Platelet distribution width 174 | 174
Monocyte percentage of white c... 173 | 173
Post bronchodilator FEV1 173 | 173
Sum eosinophil basophil counts 173 | 173
White blood cell count 172 | 172
3-hydroxy-1-methylpropylmercap... 166 | 166
Eosinophil percentage of granu... 163 | 163
Eosinophil percentage of white... 163 | 163
Reticulocyte fraction of red c... 163 | 163
Ulcerative colitis 163 | 163
Granulocyte percentage of myel... 162 | 162
Itch intensity from mosquito b... 162 | 162
Systemic lupus erythematosus 159 | 159
High light scatter reticulocyt... 158 | 158
Lymphocyte counts 158 | 158
Reticulocyte count 158 | 158
Blood metabolite levels 157 | 157
Neutrophil count 154 | 154
High light scatter reticulocyt... 153 | 153
Neutrophil percentage of granu... 153 | 153
3-hydroxypropylmercapturic aci... 150 | 150
Tonsillectomy 149 | 149
Diastolic blood pressure 144 | 144
Sum basophil neutrophil counts 140 | 140
Autism spectrum disorder or sc... 134 | 134
Myeloid white cell count 133 | 133
Granulocyte count 132 | 132
Sum neutrophil eosinophil coun... 129 | 129
Colorectal cancer 126 | 126
Alzheimer disease and age of o... 124 | 124
Multiple sclerosis 124 | 124
Cholesterol, total 123 | 123
Night sleep phenotypes 123 | 123
Lung cancer 122 | 122
Lymphocyte percentage of white... 122 | 122
Menarche (age at onset) 122 | 122
Neutrophil percentage of white... 121 | 121
Rheumatoid arthritis 121 | 121
Systolic blood pressure 120 | 120
Immature fraction of reticuloc... 118 | 118
Diisocyanate-induced asthma 116 | 116
HDL cholesterol 116 | 116
Allergic disease (asthma, hay ... 115 | 115
Educational attainment (years ... 114 | 114
Hematocrit 113 | 113
Hemoglobin concentration 112 | 112
LDL cholesterol 110 | 110
QT interval 110 | 110
Waist circumference adjusted f... 110 | 110
Mosquito bite size 107 | 107
Asthma 106 | 106
Lobe attachment (rater-scored ... 103 | 103
Peripheral arterial disease (t... 101 | 101
Pulse pressure 97 | 97
Bipolar disorder 94 | 94
Major depressive disorder 94 | 94
Prostate cancer 92 | 92
Parkinson's disease 90 | 90
Hip circumference adjusted for... 89 | 89
Metabolite levels 87 | 87
Triglycerides 87 | 87
Colonoscopy-negative controls ... 85 | 85
Mean corpuscular hemoglobin co... 85 | 85
Itch intensity from mosquito b... 84 | 84
Bipolar disorder and schizophr... 83 | 83
Resting heart rate 82 | 82
Macrophage inflammatory protei... 81 | 81
Migraine 81 | 81
Waist-to-hip ratio adjusted fo... 81 | 81
PR interval in Tripanosoma cru... 80 | 80
Cognitive performance 79 | 79
Glomerular filtration rate (cr... 78 | 78
Late-onset Alzheimer's disease 78 | 78
Waist circumference adjusted f... 75 | 75
Tuberculosis 73 | 73
Type 1 diabetes 73 | 73
Morning vs. evening chronotype 72 | 72

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Gamma-aminobutyric acid receptor subunit alpha-4 GABRA4 Tclin Ion Channel -1.28622 17.7 291
Glycine receptor subunit beta GLRB Tclin Ion Channel -1.28276 18.0 97
Dynein heavy chain 11, axonemal DNAH11 Tbio Non-IDG -1.26479 16.9 50
Diacylglycerol kinase iota DGKI Tbio Enzyme -0.89505 7.70 152
Mitochondrial import receptor subunit TOM40 homolog TOMM40 Tbio Non-IDG -2.21973 158.9 94
Solute carrier organic anion transporter family member 6A1 SLCO6A1 Tbio Transporter -1.23205 15.5 67
Angiopoietin-1 receptor TEK Tclin Kinase -3.00257 906.7 1009
Interferon gamma receptor 2 IFNGR2 Tbio Non-IDG -1.70048 44.2 264
Striatin STRN Tbio Non-IDG -1.71700 58.5 130
Apolipoprotein E APOE Tbio Non-IDG -4.20176 15904.9 976