Development Level

Tbio 32 | 11,445
Tchem 4 | 1,598
Tclin 3 | 613
Tdark 2 | 6,588

IMPC Phenotype

decreased grip strength 5 | 116
preweaning lethality, complete... 5 | 979
abnormal behavior 2 | 298
abnormal bone structure 2 | 187
abnormal eye morphology 2 | 68
abnormal heart morphology 2 | 162
abnormal lens morphology 2 | 81
abnormal seminal vesicle morph... 2 | 114
abnormal sleep behavior 2 | 70
cataract 2 | 92
decreased startle reflex 2 | 75
decreased total body fat amoun... 2 | 207
enlarged heart 2 | 210
hypoactivity 2 | 132
increased circulating alkaline... 2 | 122
increased or absent threshold ... 2 | 101
mydriasis 2 | 6
preweaning lethality, incomple... 2 | 499
vertebral transformation 2 | 12
abnormal behavioral response t... 1 | 66
abnormal coat-hair pigmentatio... 1 | 64
abnormal cornea morphology 1 | 31
abnormal embryo size 1 | 220
abnormal embryo turning 1 | 31
abnormal incisor morphology 1 | 4
abnormal iris morphology 1 | 13
abnormal locomotor activation 1 | 16
abnormal pupil morphology 1 | 2
abnormal retina morphology 1 | 71
abnormal retinal outer nuclear... 1 | 3
abnormal social-conspecific in... 1 | 3
abnormal vertebral arch morpho... 1 | 9
anophthalmia 1 | 33
corneal opacity 1 | 32
decreased CD4-positive, alpha ... 1 | 7
decreased CD8-positive, alpha-... 1 | 8
decreased T cell number 1 | 15
decreased body weight 1 | 161
decreased bone mineral density 1 | 126
decreased caudal vertebrae num... 1 | 53
decreased circulating amylase ... 1 | 28
decreased circulating fructosa... 1 | 30
decreased circulating serum al... 1 | 82
decreased circulating triglyce... 1 | 79
decreased erythrocyte cell num... 1 | 62
decreased exploration in new e... 1 | 11
decreased fasted circulating g... 1 | 65
decreased prepulse inhibition 1 | 82
decreased threshold for audito... 1 | 26
decreased total retina thickne... 1 | 17
decreased vertical activity 1 | 208
embryonic lethality prior to o... 1 | 239
embryonic lethality prior to t... 1 | 278
fusion of vertebral arches 1 | 7
improved glucose tolerance 1 | 79
increased B cell number 1 | 9
increased circulating HDL chol... 1 | 80
increased circulating choleste... 1 | 66
increased circulating triglyce... 1 | 42
increased coping response 1 | 4
increased exploration in new e... 1 | 8
increased fasted circulating g... 1 | 76
increased heart rate 1 | 23
increased hemoglobin content 1 | 45
increased mean corpuscular hem... 1 | 96
increased mean corpuscular vol... 1 | 92
irregularly shaped pupil 1 | 7
polycystic kidney 1 | 15
prenatal lethality prior to he... 1 | 87
shortened ST segment 1 | 10
thrombocytopenia 1 | 56

Disease

Carcinoma 32 | 11,493
ovarian cancer 26 | 8,520
psoriasis 21 | 6,694
medulloblastoma, large-cell 20 | 6,241
glioblastoma 18 | 5,792
osteosarcoma 18 | 7,950
atypical teratoid / rhabdoid tumor 16 | 5,112
Kidney cancer 15 | 2,613
adult high grade glioma 14 | 3,801
ependymoma 14 | 4,679
astrocytic glioma 13 | 2,597
group 3 medulloblastoma 13 | 4,104
lung cancer 12 | 4,740
oligodendroglioma 12 | 2,850
Astrocytoma, Pilocytic 10 | 3,081
Breast cancer 10 | 3,578
invasive ductal carcinoma 9 | 2,951
lung carcinoma 9 | 2,843
non-small cell lung cancer 9 | 2,890
Pick disease 8 | 1,894
group 4 medulloblastoma 8 | 1,855
subependymal giant cell astrocytoma 8 | 2,287
Intellectual disability 7 | 1,016
cystic fibrosis 7 | 1,696
intraductal papillary-mucinous neoplasm (IPMN) 7 | 3,291
lung adenocarcinoma 7 | 2,716
primitive neuroectodermal tumor 7 | 3,035
tuberculosis 7 | 2,010
Cancer 6 | 2,499
Rheumatoid arthritis 6 | 1,191
dermatomyositis 6 | 966
intraductal papillary-mucinous adenoma (IPMA) 6 | 2,955
intraductal papillary-mucinous carcinoma (IPMC) 6 | 2,989
pituitary cancer 6 | 1,972
Melanoma 5 | 711
Obesity 5 | 678
Parkinson's disease 5 | 392
Schizophrenia 5 | 1,160
Waldenstrons macroglobulinemia 5 | 765
breast carcinoma 5 | 1,638
colon cancer 5 | 1,478
interstitial cystitis 5 | 2,312
juvenile dermatomyositis 5 | 1,187
malignant mesothelioma 5 | 3,232
spina bifida 5 | 1,074
ulcerative colitis 5 | 1,819
Acquired metabolic disease 4 | 336
Adenoid Cystic Carcinoma 4 | 99
Amyotrophic lateral sclerosis 4 | 451
Carcinoma, Adenoid Cystic 4 | 99
Depressive disorder 4 | 409
Epilepsy 4 | 792
Liver cancer 4 | 604
Skin cancer 4 | 469
acute quadriplegic myopathy 4 | 1,158
diabetes mellitus 4 | 1,728
interstitial lung disease 4 | 298
non-small cell lung carcinoma 4 | 317
pancreatic cancer 4 | 2,398
pancreatic carcinoma 4 | 562
primary Sjogren syndrome 4 | 735
progressive supranuclear palsy 4 | 676
Alzheimer's disease 3 | 658
Atopic dermatitis 3 | 952
Autistic Disorder 3 | 364
Bipolar Disorder 3 | 666
Chronic obstructive pulmonary disease 3 | 184
Crohn's disease 3 | 321
Kidney disease 3 | 430
Seizures 3 | 596
Type 2 diabetes mellitus 3 | 272
Vascular disease 3 | 319
acute myeloid leukemia 3 | 783
cutaneous lupus erythematosus 3 | 1,057
ductal carcinoma in situ 3 | 1,745
esophageal adenocarcinoma 3 | 737
nasopharyngeal carcinoma 3 | 1,058
Aggressive behavior 2 | 75
Aggressive reaction 2 | 75
Anemia 2 | 365
Atherosclerosis 2 | 291
Attention deficit hyperactivity disorder 2 | 278
Cerebrovascular disease 2 | 238
Coronary artery disease 2 | 268
Delayed speech and language development 2 | 112
Down syndrome 2 | 499
Endometriosis 2 | 540
Language Delay 2 | 112
Mental Depression 2 | 333
Multiple Sclerosis 2 | 540
Physical aggression 2 | 76
Prostatic Neoplasms 2 | 495
Speech Delay 2 | 112
Speech impairment 2 | 112
Substance-Related Disorders 2 | 115
adrenocortical carcinoma 2 | 1,428
astrocytoma 2 | 1,146
mucosa-associated lymphoid tissue lymphoma 2 | 484
pancreatic ductal adenocarcinoma liver metastasis 2 | 1,962
substance-related disorder 2 | 162

Tissue

Digestive Tract 41 | 17,369
Endocrine System 41 | 18,159
Male tissues 41 | 17,142
Skin and soft tissues 41 | 17,230
Nervous System 40 | 16,725
Urinary Tract 40 | 16,678
Blood and immune system 39 | 16,909
Female tissues 39 | 17,400
Liver and Pancreas 38 | 16,750
Respiratory system 38 | 16,393
Cardiovascular System 37 | 15,192

Target Family

Non-IDG 23 | 12,091
Enzyme 8 | 4,145
Transcription Factor 6 | 1,400
Epigenetic 1 | 242
GPCR 1 | 408
Nuclear Receptor 1 | 48
Transporter 1 | 473

GWAS Trait

Cognitive ability 41 | 41
Obesity-related traits 569 | 569
Schizophrenia 533 | 533
Breast cancer 492 | 492
Body mass index 379 | 379
Height 369 | 369
Coronary artery disease 367 | 367
Blood protein levels 351 | 351
Post bronchodilator FEV1-FVC r... 308 | 308
Mean corpuscular volume 283 | 283
Platelet count 275 | 275
Intelligence (multi-trait anal... 267 | 267
Mean platelet volume 253 | 253
IgG glycosylation 250 | 250
Mean corpuscular hemoglobin 238 | 238
Inflammatory bowel disease 235 | 235
Plateletcrit 227 | 227
Crohn's disease 215 | 215
Type 2 diabetes 210 | 210
Red blood cell count 191 | 191
Monocyte count 183 | 183
Red cell distribution width 182 | 182
Eosinophil counts 180 | 180
Neuroticism 180 | 180
Platelet distribution width 174 | 174
Monocyte percentage of white c... 173 | 173
Post bronchodilator FEV1 173 | 173
Sum eosinophil basophil counts 173 | 173
White blood cell count 172 | 172
3-hydroxy-1-methylpropylmercap... 166 | 166
Eosinophil percentage of granu... 163 | 163
Eosinophil percentage of white... 163 | 163
Reticulocyte fraction of red c... 163 | 163
Ulcerative colitis 163 | 163
Granulocyte percentage of myel... 162 | 162
Itch intensity from mosquito b... 162 | 162
Systemic lupus erythematosus 159 | 159
High light scatter reticulocyt... 158 | 158
Lymphocyte counts 158 | 158
Reticulocyte count 158 | 158
Blood metabolite levels 157 | 157
Neutrophil count 154 | 154
High light scatter reticulocyt... 153 | 153
Neutrophil percentage of granu... 153 | 153
3-hydroxypropylmercapturic aci... 150 | 150
Tonsillectomy 149 | 149
Diastolic blood pressure 144 | 144
Sum basophil neutrophil counts 140 | 140
Autism spectrum disorder or sc... 134 | 134
Myeloid white cell count 133 | 133
Granulocyte count 132 | 132
Sum neutrophil eosinophil coun... 129 | 129
Colorectal cancer 126 | 126
Alzheimer disease and age of o... 124 | 124
Multiple sclerosis 124 | 124
Cholesterol, total 123 | 123
Night sleep phenotypes 123 | 123
Lung cancer 122 | 122
Lymphocyte percentage of white... 122 | 122
Menarche (age at onset) 122 | 122
Neutrophil percentage of white... 121 | 121
Rheumatoid arthritis 121 | 121
Systolic blood pressure 120 | 120
Immature fraction of reticuloc... 118 | 118
Diisocyanate-induced asthma 116 | 116
HDL cholesterol 116 | 116
Allergic disease (asthma, hay ... 115 | 115
Educational attainment (years ... 114 | 114
Hematocrit 113 | 113
Hemoglobin concentration 112 | 112
LDL cholesterol 110 | 110
QT interval 110 | 110
Waist circumference adjusted f... 110 | 110
Mosquito bite size 107 | 107
Asthma 106 | 106
Lobe attachment (rater-scored ... 103 | 103
Peripheral arterial disease (t... 101 | 101
Pulse pressure 97 | 97
Bipolar disorder 94 | 94
Major depressive disorder 94 | 94
Prostate cancer 92 | 92
Parkinson's disease 90 | 90
Hip circumference adjusted for... 89 | 89
Metabolite levels 87 | 87
Triglycerides 87 | 87
Colonoscopy-negative controls ... 85 | 85
Mean corpuscular hemoglobin co... 85 | 85
Itch intensity from mosquito b... 84 | 84
Bipolar disorder and schizophr... 83 | 83
Resting heart rate 82 | 82
Macrophage inflammatory protei... 81 | 81
Migraine 81 | 81
Waist-to-hip ratio adjusted fo... 81 | 81
PR interval in Tripanosoma cru... 80 | 80
Cognitive performance 79 | 79
Glomerular filtration rate (cr... 78 | 78
Late-onset Alzheimer's disease 78 | 78
Waist circumference adjusted f... 75 | 75
Tuberculosis 73 | 73
Type 1 diabetes 73 | 73
Morning vs. evening chronotype 72 | 72

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Zinc finger protein 638 ZNF638 Tbio Non-IDG -0.68946 6.04 67
Forkhead box protein O6 FOXO6 Tbio Transcription Factor -1.13890 17.2 38
AF4/FMR2 family member 3 AFF3 Tbio Transcription Factor -1.37981 25.3 50
Forkhead box protein O3 FOXO3 Tbio Transcription Factor -2.94477 863.9 864
Dendrin DDN Tbio Non-IDG -2.11313 132.8 4
Ataxin-2-like protein ATXN2L Tbio Non-IDG -1.58925 37.9 93
B-cell lymphoma/leukemia 11A BCL11A Tbio Transcription Factor -2.16270 151.0 300
Inactive phospholipase C-like protein 2 PLCL2 Tbio Enzyme -0.30556 2.11 96
VPS10 domain-containing receptor SorCS3 SORCS3 Tbio Non-IDG -0.70549 6.30 49
Mediator of RNA polymerase II transcription subunit 27 MED27 Tbio Enzyme -1.49097 29.0 107