Development Level

Tbio 4 | 11,651
Tclin 1 | 612

IMPC Phenotype

increased bone mineral content 1 | 108

Disease

Carcinoma 4 | 11,493
osteosarcoma 4 | 7,950
Autosomal recessive predisposition 2 | 1,442
Prostate cancer 2 | 175
malignant mesothelioma 2 | 3,232
psoriasis 2 | 6,694
Adult Fanconi syndrome 1 | 12
Angioedema 1 | 38
Arthritis, Rheumatoid 1 | 174
Autosomal recessive Robinow syndrome 1 | 27
Autosomal recessive infantile hypercalcemia 1 | 2
Bone Diseases, Developmental 1 | 27
Breast Neoplasms 1 | 445
Breast Neoplasms, Male 1 | 4
Breast cancer 1 | 3,578
C1 inhibitor deficiency 1 | 8
Calcinosis 1 | 70
Cancer 1 | 2,499
Carotid Artery Thrombosis 1 | 6
Crohn's disease 1 | 321
Diabetic retinopathy 1 | 56
Disseminated intravascular coagulation 1 | 38
Epidermodysplasia verruciformis 1 | 21
FRTS1 1 | 2
Factor XII deficiency 1 | 13
Fanconi Renotubular Syndrome 2 1 | 1
Fanconi syndrome 1 | 14
Generalized aminoaciduria 1 | 9
Generalized osteopenia 1 | 99
Glycosuria 1 | 29
Hemorrhage 1 | 19
Hereditary angioneurotic edema 1 | 4
Hypercalcemia 1 | 59
Hypercalcemia, Infantile 1 | 3
Hypercalciuria 1 | 27
Hyperphosphatemia 1 | 32
Hyperphosphaturia 1 | 21
Hypertension 1 | 396
Hypochromic anemia 1 | 9
Hypophosphatemia 1 | 40
Increased serum bone-specific alkaline phosphatase 1 | 4
Increased susceptibility to fractures 1 | 21
Kidney Failure 1 | 111
Kidney disease 1 | 430
Macular degeneration 1 | 65
Mammary Neoplasms 1 | 425
Muscle Weakness 1 | 170
NEPHROLITHIASIS/OSTEOPOROSIS, HYPOPHOSPHATEMIC, 1 1 | 1
Nephrolithiasis 1 | 56
Nephrolithiasis-Osteoporosis, Hypophosphatemic, 1 1 | 1
Nonsyndromic deafness 1 | 142
Osteomalacia 1 | 35
Osteopenia 1 | 99
Osteoporosis 1 | 363
Pancreatitis 1 | 123
Partial thromboplastin time increased (finding) 1 | 11
Pleurisy 1 | 19
Prekallikrein deficiency 1 | 1
Primary biliary cirrhosis 1 | 51
Proximal tubulopathy 1 | 9
Pulmonary alveolar microlithiasis 1 | 4
Pulmonary embolism 1 | 55
Renal Insufficiency 1 | 90
Renal failure in adulthood 1 | 76
Renal phosphate wasting 1 | 7
Rheumatoid arthritis 1 | 1,191
Rickets 1 | 49
Schizophrenia 1 | 1,160
Short stature 1 | 531
Substance-Related Disorders 1 | 115
Systemic lupus erythematosus 1 | 194
Thrombosis 1 | 46
Urine phosphorous concentration above normal 1 | 21
Uterine fibroid 1 | 28
WHIM syndrome 1 | 7
ependymoma 1 | 4,679
hypophosphatemic nephrolithiasis/osteoporosis 1 1 | 1
lung cancer 1 | 4,740
lung carcinoma 1 | 2,843
nephrosclerosis 1 | 333
non primary Sjogren syndrome sicca 1 | 891
ovarian cancer 1 | 8,520
tuberculosis 1 | 2,010

Tissue

Digestive Tract 5 | 17,369
Liver and Pancreas 5 | 16,750
Nervous System 5 | 16,725
Skin and soft tissues 5 | 17,230
Urinary Tract 5 | 16,678
Blood and immune system 4 | 16,909
Endocrine System 4 | 18,159
Female tissues 4 | 17,400
Male tissues 4 | 17,142
Respiratory system 4 | 16,393
Cardiovascular System 3 | 15,192

Target Family

Enzyme 1 | 4,145
Ion Channel 1 | 344
Kinase 1 | 634
Non-IDG 1 | 12,091
Transporter 1 | 473

GWAS Trait

Circulating chromogranin pepti... 5 | 5
Obesity-related traits 569 | 569
Schizophrenia 533 | 533
Breast cancer 492 | 492
Body mass index 379 | 379
Height 369 | 369
Coronary artery disease 367 | 367
Blood protein levels 351 | 351
Post bronchodilator FEV1-FVC r... 308 | 308
Mean corpuscular volume 283 | 283
Platelet count 275 | 275
Intelligence (multi-trait anal... 267 | 267
Mean platelet volume 253 | 253
IgG glycosylation 250 | 250
Mean corpuscular hemoglobin 238 | 238
Inflammatory bowel disease 235 | 235
Plateletcrit 227 | 227
Crohn's disease 215 | 215
Type 2 diabetes 210 | 210
Red blood cell count 191 | 191
Monocyte count 183 | 183
Red cell distribution width 182 | 182
Eosinophil counts 180 | 180
Neuroticism 180 | 180
Platelet distribution width 174 | 174
Monocyte percentage of white c... 173 | 173
Post bronchodilator FEV1 173 | 173
Sum eosinophil basophil counts 173 | 173
White blood cell count 172 | 172
3-hydroxy-1-methylpropylmercap... 166 | 166
Eosinophil percentage of granu... 163 | 163
Eosinophil percentage of white... 163 | 163
Reticulocyte fraction of red c... 163 | 163
Ulcerative colitis 163 | 163
Granulocyte percentage of myel... 162 | 162
Itch intensity from mosquito b... 162 | 162
Systemic lupus erythematosus 159 | 159
High light scatter reticulocyt... 158 | 158
Lymphocyte counts 158 | 158
Reticulocyte count 158 | 158
Blood metabolite levels 157 | 157
Neutrophil count 154 | 154
High light scatter reticulocyt... 153 | 153
Neutrophil percentage of granu... 153 | 153
3-hydroxypropylmercapturic aci... 150 | 150
Tonsillectomy 149 | 149
Diastolic blood pressure 144 | 144
Sum basophil neutrophil counts 140 | 140
Autism spectrum disorder or sc... 134 | 134
Myeloid white cell count 133 | 133
Granulocyte count 132 | 132
Sum neutrophil eosinophil coun... 129 | 129
Colorectal cancer 126 | 126
Alzheimer disease and age of o... 124 | 124
Multiple sclerosis 124 | 124
Cholesterol, total 123 | 123
Night sleep phenotypes 123 | 123
Lung cancer 122 | 122
Lymphocyte percentage of white... 122 | 122
Menarche (age at onset) 122 | 122
Neutrophil percentage of white... 121 | 121
Rheumatoid arthritis 121 | 121
Systolic blood pressure 120 | 120
Immature fraction of reticuloc... 118 | 118
Diisocyanate-induced asthma 116 | 116
HDL cholesterol 116 | 116
Allergic disease (asthma, hay ... 115 | 115
Educational attainment (years ... 114 | 114
Hematocrit 113 | 113
Hemoglobin concentration 112 | 112
LDL cholesterol 110 | 110
QT interval 110 | 110
Waist circumference adjusted f... 110 | 110
Mosquito bite size 107 | 107
Asthma 106 | 106
Lobe attachment (rater-scored ... 103 | 103
Peripheral arterial disease (t... 101 | 101
Pulse pressure 97 | 97
Bipolar disorder 94 | 94
Major depressive disorder 94 | 94
Prostate cancer 92 | 92
Parkinson's disease 90 | 90
Hip circumference adjusted for... 89 | 89
Metabolite levels 87 | 87
Triglycerides 87 | 87
Colonoscopy-negative controls ... 85 | 85
Mean corpuscular hemoglobin co... 85 | 85
Itch intensity from mosquito b... 84 | 84
Bipolar disorder and schizophr... 83 | 83
Resting heart rate 82 | 82
Macrophage inflammatory protei... 81 | 81
Migraine 81 | 81
Waist-to-hip ratio adjusted fo... 81 | 81
PR interval in Tripanosoma cru... 80 | 80
Cognitive performance 79 | 79
Glomerular filtration rate (cr... 78 | 78
Late-onset Alzheimer's disease 78 | 78
Waist circumference adjusted f... 75 | 75
Tuberculosis 73 | 73
Type 1 diabetes 73 | 73
Morning vs. evening chronotype 72 | 72

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Plasma kallikrein KLKB1 Tclin Enzyme -2.89608 720.1 284
DNA repair protein RAD51 homolog 2 RAD51B Tbio Non-IDG -1.94564 84.8 171
G protein-coupled receptor kinase 6 GRK6 Tbio Kinase -1.48432 31.2 307
Sodium-dependent phosphate transport protein 2A SLC34A1 Tbio Transporter -1.98345 87.1 65
Transmembrane channel-like protein 2 TMC2 Tbio Ion Channel -1.19934 15.1 35