Development Level

Tbio 12 | 11,445
Tdark 7 | 6,588
Tchem 6 | 1,598
Tclin 1 | 613

Collection

Kinase: IDG Consortium (Comple... 1 | 37

IMPC Phenotype

abnormal behavior 2 | 298
decreased circulating triglyce... 2 | 79
decreased hemoglobin content 2 | 68
decreased mean corpuscular hem... 2 | 31
embryonic lethality prior to t... 2 | 278
hypoactivity 2 | 132
increased circulating alkaline... 2 | 122
abnormal behavioral response t... 1 | 66
abnormal bone mineralization 1 | 38
abnormal bone structure 1 | 187
abnormal coat-hair pigmentatio... 1 | 64
abnormal cornea morphology 1 | 31
abnormal embryo size 1 | 220
abnormal kidney morphology 1 | 65
abnormal lens morphology 1 | 81
abnormal locomotor behavior 1 | 24
abnormal retinal blood vessel ... 1 | 26
abnormal skin condition 1 | 6
abnormal sleep behavior 1 | 70
abnormal spleen morphology 1 | 55
abnormal tibia morphology 1 | 14
cataract 1 | 92
convulsive seizures 1 | 13
decreased body length 1 | 101
decreased body weight 1 | 161
decreased circulating HDL chol... 1 | 68
decreased circulating alkaline... 1 | 46
decreased circulating amylase ... 1 | 28
decreased circulating choleste... 1 | 93
decreased circulating glucose ... 1 | 126
decreased circulating serum al... 1 | 82
decreased circulating sodium l... 1 | 22
decreased circulating total pr... 1 | 49
decreased grip strength 1 | 116
decreased hematocrit 1 | 46
decreased lean body mass 1 | 135
decreased lymphocyte cell numb... 1 | 83
decreased mean corpuscular hem... 1 | 50
decreased prepulse inhibition 1 | 82
decreased startle reflex 1 | 75
decreased thermal nociceptive ... 1 | 2
decreased total body fat amoun... 1 | 207
decreased total retina thickne... 1 | 17
decreased vertical activity 1 | 208
enlarged heart 1 | 210
hyperactivity 1 | 148
increased body length 1 | 32
increased body temperature 1 | 9
increased body weight 1 | 25
increased bone mineral content 1 | 108
increased circulating HDL chol... 1 | 80
increased circulating chloride... 1 | 41
increased circulating choleste... 1 | 66
increased circulating creatini... 1 | 38
increased circulating free fat... 1 | 20
increased circulating glucose ... 1 | 24
increased circulating sodium l... 1 | 71
increased circulating triglyce... 1 | 42
increased erythrocyte cell num... 1 | 39
increased heart left ventricle... 1 | 4
increased heart weight 1 | 62
increased lean body mass 1 | 172
increased leukocyte cell numbe... 1 | 47
increased monocyte cell number 1 | 63
increased or absent threshold ... 1 | 101
increased red blood cell distr... 1 | 34
increased thermal nociceptive ... 1 | 9
increased total body fat amoun... 1 | 134
increased vertical activity 1 | 24
limb grasping 1 | 41
mammalian phenotype 1 | 17
pale yolk sac 1 | 25
pallor 1 | 34
prenatal lethality prior to he... 1 | 87
preweaning lethality, incomple... 1 | 499
shortened ST segment 1 | 10
thick ventricular wall 1 | 7
unresponsive to tactile stimul... 1 | 8

Disease

Carcinoma 15 | 11,493
ovarian cancer 14 | 8,520
medulloblastoma, large-cell 12 | 6,241
osteosarcoma 11 | 7,950
atypical teratoid / rhabdoid tumor 9 | 5,112
glioblastoma 9 | 5,792
Kidney cancer 7 | 2,613
psoriasis 7 | 6,694
astrocytic glioma 6 | 2,597
ependymoma 6 | 4,679
lung cancer 6 | 4,740
Alzheimer's disease 5 | 658
Astrocytoma, Pilocytic 5 | 3,081
Liver cancer 5 | 604
invasive ductal carcinoma 5 | 2,951
malignant mesothelioma 5 | 3,232
oligodendroglioma 5 | 2,850
primitive neuroectodermal tumor 5 | 3,035
Bipolar Disorder 4 | 666
adult high grade glioma 4 | 3,801
group 3 medulloblastoma 4 | 4,104
group 4 medulloblastoma 4 | 1,855
intraductal papillary-mucinous adenoma (IPMA) 4 | 2,955
intraductal papillary-mucinous carcinoma (IPMC) 4 | 2,989
intraductal papillary-mucinous neoplasm (IPMN) 4 | 3,291
subependymal giant cell astrocytoma 4 | 2,287
tuberculosis 4 | 2,010
Breast cancer 3 | 3,578
Depressive disorder 3 | 409
Mental Depression 3 | 333
Mood Disorders 3 | 184
Multiple Sclerosis 3 | 540
Pick disease 3 | 1,894
Schizophrenia 3 | 1,160
acute myeloid leukemia 3 | 783
lung adenocarcinoma 3 | 2,716
lung carcinoma 3 | 2,843
non-small cell lung cancer 3 | 2,890
pancreatic cancer 3 | 2,398
pancreatic ductal adenocarcinoma liver metastasis 3 | 1,962
spina bifida 3 | 1,074
ulcerative colitis 3 | 1,819
Cancer 2 | 2,499
Essential Hypertension 2 | 94
Heart disease 2 | 306
Hyperactive behavior 2 | 91
Melanoma 2 | 711
Migraine 2 | 83
Obesity 2 | 678
Osteoporosis 2 | 363
Prostate cancer 2 | 175
Skin cancer 2 | 469
Substance Withdrawal Syndrome 2 | 55
Werner syndrome 2 | 29
breast carcinoma 2 | 1,638
chronic rhinosinusitis 2 | 512
colon cancer 2 | 1,478
cystic fibrosis 2 | 1,696
gastric cancer 2 | 459
hepatocellular carcinoma 2 | 547
interstitial cystitis 2 | 2,312
juvenile dermatomyositis 2 | 1,187
pituitary cancer 2 | 1,972
progressive supranuclear palsy 2 | 676
Acquired immunodeficiency syndrome 1 | 197
Adenocarcinoma 1 | 122
Agoraphobia 1 | 21
Amnestic disorder 1 | 35
Asperger syndrome 1 | 37
Asphyxiating thoracic dystrophy 1 | 44
Asthenopia 1 | 10
Autosomal dominant nonsyndromic deafness 13 1 | 2
Autosomal dominant nonsyndromic deafness 21 1 | 3
Autosomal dominant nonsyndromic deafness 31 1 | 3
Cardiac arrest 1 | 36
Cell Transformation, Neoplastic 1 | 97
Chronic kidney disease stage 5 1 | 31
Cocaine Dependence 1 | 51
Common variable immunodeficiency 1 | 101
Decreased visual acuity, progressive 1 | 36
Generalized anxiety disorder 1 | 29
Hyperkinesis 1 | 32
Keratoconjunctivitis sicca 1 | 25
Macular degeneration 1 | 65
Malignant neoplasm of prostate 1 | 11
Nager acrofacial dysostosis 1 | 21
Neoplastic Cell Transformation 1 | 89
Nephritis, Tubulointerstitial 1 | 8
Pitt-Hopkins syndrome 1 | 20
Premature Menopause 1 | 31
Prevention of Cardiac Transplant Rejection 1 | 15
Prevention of Kidney Transplant Rejection 1 | 17
Prevention of Liver Transplant Rejection 1 | 15
Progressive visual loss 1 | 36
Psychoses, Substance-Induced 1 | 17
Sensenbrenner syndrome 1 | 17
Severe Recalcitrant Psoriasis 1 | 12
Tear film insufficiency 1 | 15
Type 2 Diabetes Mellitus Treatment Adjunct 1 | 7
Uterine fibroid 1 | 28

Tissue

Endocrine System 25 | 18,159
Nervous System 24 | 16,725
Cardiovascular System 23 | 15,192
Digestive Tract 23 | 17,369
Female tissues 23 | 17,400
Urinary Tract 23 | 16,678
Blood and immune system 22 | 16,909
Liver and Pancreas 22 | 16,750
Male tissues 22 | 17,142
Respiratory system 22 | 16,393
Skin and soft tissues 22 | 17,230

Target Family

Enzyme 11 | 4,145
Non-IDG 10 | 12,091
GPCR 2 | 408
Transcription Factor 2 | 1,400
Kinase 1 | 634

GWAS Trait

Chronotype 26 | 26
Obesity-related traits 569 | 569
Schizophrenia 533 | 533
Breast cancer 492 | 492
Body mass index 379 | 379
Height 369 | 369
Coronary artery disease 367 | 367
Blood protein levels 351 | 351
Post bronchodilator FEV1-FVC r... 308 | 308
Mean corpuscular volume 283 | 283
Platelet count 275 | 275
Intelligence (multi-trait anal... 267 | 267
Mean platelet volume 253 | 253
IgG glycosylation 250 | 250
Mean corpuscular hemoglobin 238 | 238
Inflammatory bowel disease 235 | 235
Plateletcrit 227 | 227
Crohn's disease 215 | 215
Type 2 diabetes 210 | 210
Red blood cell count 191 | 191
Monocyte count 183 | 183
Red cell distribution width 182 | 182
Eosinophil counts 180 | 180
Neuroticism 180 | 180
Platelet distribution width 174 | 174
Monocyte percentage of white c... 173 | 173
Post bronchodilator FEV1 173 | 173
Sum eosinophil basophil counts 173 | 173
White blood cell count 172 | 172
3-hydroxy-1-methylpropylmercap... 166 | 166
Eosinophil percentage of granu... 163 | 163
Eosinophil percentage of white... 163 | 163
Reticulocyte fraction of red c... 163 | 163
Ulcerative colitis 163 | 163
Granulocyte percentage of myel... 162 | 162
Itch intensity from mosquito b... 162 | 162
Systemic lupus erythematosus 159 | 159
High light scatter reticulocyt... 158 | 158
Lymphocyte counts 158 | 158
Reticulocyte count 158 | 158
Blood metabolite levels 157 | 157
Neutrophil count 154 | 154
High light scatter reticulocyt... 153 | 153
Neutrophil percentage of granu... 153 | 153
3-hydroxypropylmercapturic aci... 150 | 150
Tonsillectomy 149 | 149
Diastolic blood pressure 144 | 144
Sum basophil neutrophil counts 140 | 140
Autism spectrum disorder or sc... 134 | 134
Myeloid white cell count 133 | 133
Granulocyte count 132 | 132
Sum neutrophil eosinophil coun... 129 | 129
Colorectal cancer 126 | 126
Alzheimer disease and age of o... 124 | 124
Multiple sclerosis 124 | 124
Cholesterol, total 123 | 123
Night sleep phenotypes 123 | 123
Lung cancer 122 | 122
Lymphocyte percentage of white... 122 | 122
Menarche (age at onset) 122 | 122
Neutrophil percentage of white... 121 | 121
Rheumatoid arthritis 121 | 121
Systolic blood pressure 120 | 120
Immature fraction of reticuloc... 118 | 118
Diisocyanate-induced asthma 116 | 116
HDL cholesterol 116 | 116
Allergic disease (asthma, hay ... 115 | 115
Educational attainment (years ... 114 | 114
Hematocrit 113 | 113
Hemoglobin concentration 112 | 112
LDL cholesterol 110 | 110
QT interval 110 | 110
Waist circumference adjusted f... 110 | 110
Mosquito bite size 107 | 107
Asthma 106 | 106
Lobe attachment (rater-scored ... 103 | 103
Peripheral arterial disease (t... 101 | 101
Pulse pressure 97 | 97
Bipolar disorder 94 | 94
Major depressive disorder 94 | 94
Prostate cancer 92 | 92
Parkinson's disease 90 | 90
Hip circumference adjusted for... 89 | 89
Metabolite levels 87 | 87
Triglycerides 87 | 87
Colonoscopy-negative controls ... 85 | 85
Mean corpuscular hemoglobin co... 85 | 85
Itch intensity from mosquito b... 84 | 84
Bipolar disorder and schizophr... 83 | 83
Resting heart rate 82 | 82
Macrophage inflammatory protei... 81 | 81
Migraine 81 | 81
Waist-to-hip ratio adjusted fo... 81 | 81
PR interval in Tripanosoma cru... 80 | 80
Cognitive performance 79 | 79
Glomerular filtration rate (cr... 78 | 78
Late-onset Alzheimer's disease 78 | 78
Waist circumference adjusted f... 75 | 75
Tuberculosis 73 | 73
Type 1 diabetes 73 | 73
Morning vs. evening chronotype 72 | 72

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
2-5A-dependent ribonuclease RNASEL Tchem Kinase -2.71673 525.8 127
Nuclear factor NF-kappa-B p105 subunit NFKB1 Tchem Transcription Factor -2.74349 505.0 1762
Period circadian protein homolog 2 PER2 Tchem Non-IDG -2.67778 457.4 219
Neuroblastoma suppressor of tumorigenicity 1 NBL1 Tbio Non-IDG -2.58132 362.9 217
5-hydroxytryptamine receptor 6 HTR6 Tchem GPCR -2.31880 213.2 64
Peptidyl-prolyl cis-trans isomerase FKBP1B FKBP1B Tchem Enzyme -2.09568 114.2 84
Adenylate cyclase type 8 ADCY8 Tbio Enzyme -2.04645 112.4 147
Beta-mannosidase MANBA Tchem Enzyme -2.02551 103.8 50
Mitochondrial peptide methionine sulfoxide reductase MSRA Tbio Enzyme -1.92325 88.1 167
Gamma-secretase subunit APH-1A APH1A Tbio Enzyme -1.87175 70.7 290