Development Level

Tbio 27 | 11,651
Tdark 6 | 6,593
Tchem 3 | 1,388
Tclin 3 | 612

Collection

GPCR: IDG Consortium (Complete... 1 | 25

IMPC Phenotype

decreased lean body mass 2 | 135
abnormal bone structure 1 | 187
abnormal thoracic cage shape 1 | 3
decreased blood urea nitrogen ... 1 | 51
decreased body weight 1 | 161
decreased bone mineral content 1 | 151
decreased circulating HDL chol... 1 | 68
decreased circulating aspartat... 1 | 34
decreased circulating chloride... 1 | 30
decreased circulating choleste... 1 | 93
decreased circulating glucose ... 1 | 126
decreased circulating phosphat... 1 | 27
decreased exploration in new e... 1 | 11
decreased mean corpuscular hem... 1 | 31
decreased red blood cell distr... 1 | 41
decreased startle reflex 1 | 75
decreased total body fat amoun... 1 | 207
enlarged spleen 1 | 41
impaired pupillary reflex 1 | 26
improved glucose tolerance 1 | 79
increased blood urea nitrogen ... 1 | 48
increased bone mineral content 1 | 108
increased circulating HDL chol... 1 | 80
increased circulating calcium ... 1 | 34
increased circulating choleste... 1 | 66
increased circulating serum al... 1 | 22
increased circulating total pr... 1 | 28
increased fasted circulating g... 1 | 76
increased grip strength 1 | 41
increased lean body mass 1 | 172
prenatal lethality prior to he... 1 | 87
preweaning lethality, complete... 1 | 979
vertebral transformation 1 | 12

Disease

Carcinoma 31 | 11,493
Chronic obstructive pulmonary disease 19 | 184
ovarian cancer 19 | 8,520
medulloblastoma, large-cell 18 | 6,241
atypical teratoid / rhabdoid tumor 17 | 5,112
glioblastoma 17 | 5,792
lung cancer 16 | 4,740
osteosarcoma 15 | 7,950
psoriasis 14 | 6,694
ependymoma 13 | 4,679
lung carcinoma 13 | 2,843
malignant mesothelioma 13 | 3,232
Astrocytoma, Pilocytic 11 | 3,081
group 3 medulloblastoma 11 | 4,104
non-small cell lung cancer 11 | 2,890
primitive neuroectodermal tumor 11 | 3,035
lung adenocarcinoma 10 | 2,716
Breast cancer 9 | 3,578
adrenocortical carcinoma 9 | 1,428
adult high grade glioma 9 | 3,801
interstitial cystitis 9 | 2,312
oligodendroglioma 9 | 2,850
Pick disease 8 | 1,894
cystic fibrosis 8 | 1,696
Cancer 7 | 2,499
Kidney cancer 7 | 2,613
Melanoma 6 | 711
astrocytic glioma 6 | 2,597
group 4 medulloblastoma 6 | 1,855
intraductal papillary-mucinous neoplasm (IPMN) 6 | 3,291
invasive ductal carcinoma 6 | 2,951
subependymal giant cell astrocytoma 6 | 2,287
Lung Neoplasms 5 | 232
Pulmonary Disease, Chronic Obstructive 5 | 31
Rheumatoid arthritis 5 | 1,191
Schizophrenia 5 | 1,160
aldosterone-producing adenoma 5 | 665
ductal carcinoma in situ 5 | 1,745
interstitial lung disease 5 | 298
intraductal papillary-mucinous carcinoma (IPMC) 5 | 2,989
substance-related disorder 5 | 162
ulcerative colitis 5 | 1,819
Endometriosis 4 | 540
Multiple myeloma 4 | 1,332
Nicotine dependence 4 | 54
Prostatic Neoplasms 4 | 495
TOBACCO ADDICTION, SUSCEPTIBILITY TO 4 | 12
TOBACCO ADDICTION, SUSCEPTIBILITY TO (finding) 4 | 12
acute myeloid leukemia 4 | 783
colon cancer 4 | 1,478
intraductal papillary-mucinous adenoma (IPMA) 4 | 2,955
tuberculosis 4 | 2,010
Acquired metabolic disease 3 | 336
Adenocarcinoma 3 | 122
Lymphoid leukemia 3 | 160
Prostate cancer 3 | 175
Seizures 3 | 596
Stomach Neoplasms 3 | 300
Tobacco Use Disorder 3 | 12
active Crohn's disease 3 | 922
active ulcerative colitis 3 | 764
cutaneous lupus erythematosus 3 | 1,057
dermatomyositis 3 | 966
juvenile dermatomyositis 3 | 1,187
non primary Sjogren syndrome sicca 3 | 891
pancreatic cancer 3 | 2,398
pancreatic ductal adenocarcinoma liver metastasis 3 | 1,962
pediatric high grade glioma 3 | 1,064
pituitary cancer 3 | 1,972
posterior fossa group A ependymoma 3 | 468
Alzheimer's disease 2 | 658
Anemia 2 | 365
Bipolar Disorder 2 | 666
Cognitive disorder 2 | 50
Depressive disorder 2 | 409
Diarrhea 2 | 253
Duchenne muscular dystrophy 2 | 601
Epilepsy 2 | 792
Failure to gain weight 2 | 365
Liver cancer 2 | 604
Parkinson's disease 2 | 392
Pediatric failure to thrive 2 | 365
Polycystic ovary syndrome 2 | 360
Skin cancer 2 | 469
Substance-Related Disorders 2 | 115
Waldenstrons macroglobulinemia 2 | 765
acute quadriplegic myopathy 2 | 1,158
astrocytoma 2 | 1,146
atypical teratoid/rhabdoid tumor 2 | 357
autosomal dominant Emery-Dreifuss muscular dystrophy 2 | 510
breast carcinoma 2 | 1,638
chronic rhinosinusitis 2 | 512
fibroadenoma 2 | 559
gastric carcinoma 2 | 807
nasopharyngeal carcinoma 2 | 1,058
non diabetic and post-ischemic heart failure 2 | 200
posterior fossa group B ependymoma 2 | 416
primary pancreatic ductal adenocarcinoma 2 | 1,109
progressive supranuclear palsy 2 | 676
spina bifida 2 | 1,074

Tissue

Endocrine System 39 | 18,159
Female tissues 39 | 17,400
Liver and Pancreas 39 | 16,750
Respiratory system 39 | 16,393
Digestive Tract 38 | 17,369
Male tissues 38 | 17,142
Skin and soft tissues 38 | 17,230
Urinary Tract 38 | 16,678
Blood and immune system 37 | 16,909
Cardiovascular System 36 | 15,192
Nervous System 36 | 16,725

Target Family

Non-IDG 26 | 12,091
Enzyme 8 | 4,145
GPCR 2 | 408
Ion Channel 2 | 344
Nuclear Receptor 1 | 48

GWAS Trait

Chronic obstructive pulmonary ... 39 | 39
Obesity-related traits 569 | 569
Schizophrenia 533 | 533
Breast cancer 492 | 492
Body mass index 379 | 379
Height 369 | 369
Coronary artery disease 367 | 367
Blood protein levels 351 | 351
Post bronchodilator FEV1-FVC r... 308 | 308
Mean corpuscular volume 283 | 283
Platelet count 275 | 275
Intelligence (multi-trait anal... 267 | 267
Mean platelet volume 253 | 253
IgG glycosylation 250 | 250
Mean corpuscular hemoglobin 238 | 238
Inflammatory bowel disease 235 | 235
Plateletcrit 227 | 227
Crohn's disease 215 | 215
Type 2 diabetes 210 | 210
Red blood cell count 191 | 191
Monocyte count 183 | 183
Red cell distribution width 182 | 182
Eosinophil counts 180 | 180
Neuroticism 180 | 180
Platelet distribution width 174 | 174
Monocyte percentage of white c... 173 | 173
Post bronchodilator FEV1 173 | 173
Sum eosinophil basophil counts 173 | 173
White blood cell count 172 | 172
3-hydroxy-1-methylpropylmercap... 166 | 166
Eosinophil percentage of granu... 163 | 163
Eosinophil percentage of white... 163 | 163
Reticulocyte fraction of red c... 163 | 163
Ulcerative colitis 163 | 163
Granulocyte percentage of myel... 162 | 162
Itch intensity from mosquito b... 162 | 162
Systemic lupus erythematosus 159 | 159
High light scatter reticulocyt... 158 | 158
Lymphocyte counts 158 | 158
Reticulocyte count 158 | 158
Blood metabolite levels 157 | 157
Neutrophil count 154 | 154
High light scatter reticulocyt... 153 | 153
Neutrophil percentage of granu... 153 | 153
3-hydroxypropylmercapturic aci... 150 | 150
Tonsillectomy 149 | 149
Diastolic blood pressure 144 | 144
Sum basophil neutrophil counts 140 | 140
Autism spectrum disorder or sc... 134 | 134
Myeloid white cell count 133 | 133
Granulocyte count 132 | 132
Sum neutrophil eosinophil coun... 129 | 129
Colorectal cancer 126 | 126
Alzheimer disease and age of o... 124 | 124
Multiple sclerosis 124 | 124
Cholesterol, total 123 | 123
Night sleep phenotypes 123 | 123
Lung cancer 122 | 122
Lymphocyte percentage of white... 122 | 122
Menarche (age at onset) 122 | 122
Neutrophil percentage of white... 121 | 121
Rheumatoid arthritis 121 | 121
Systolic blood pressure 120 | 120
Immature fraction of reticuloc... 118 | 118
Diisocyanate-induced asthma 116 | 116
HDL cholesterol 116 | 116
Allergic disease (asthma, hay ... 115 | 115
Educational attainment (years ... 114 | 114
Hematocrit 113 | 113
Hemoglobin concentration 112 | 112
LDL cholesterol 110 | 110
QT interval 110 | 110
Waist circumference adjusted f... 110 | 110
Mosquito bite size 107 | 107
Asthma 106 | 106
Lobe attachment (rater-scored ... 103 | 103
Peripheral arterial disease (t... 101 | 101
Pulse pressure 97 | 97
Bipolar disorder 94 | 94
Major depressive disorder 94 | 94
Prostate cancer 92 | 92
Parkinson's disease 90 | 90
Hip circumference adjusted for... 89 | 89
Metabolite levels 87 | 87
Triglycerides 87 | 87
Colonoscopy-negative controls ... 85 | 85
Mean corpuscular hemoglobin co... 85 | 85
Itch intensity from mosquito b... 84 | 84
Bipolar disorder and schizophr... 83 | 83
Resting heart rate 82 | 82
Macrophage inflammatory protei... 81 | 81
Migraine 81 | 81
Waist-to-hip ratio adjusted fo... 81 | 81
PR interval in Tripanosoma cru... 80 | 80
Cognitive performance 79 | 79
Glomerular filtration rate (cr... 78 | 78
Late-onset Alzheimer's disease 78 | 78
Waist circumference adjusted f... 75 | 75
Tuberculosis 73 | 73
Type 1 diabetes 73 | 73
Morning vs. evening chronotype 72 | 72

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Disks large homolog 2 DLG2 Tbio Non-IDG -1.75838 53.6 227
Rho guanine nucleotide exchange factor 38 ARHGEF38 Tdark Non-IDG 0.85 0.14 8
Protein FAM13A FAM13A Tbio Non-IDG -1.32713 21.6 19
Thrombospondin type-1 domain-containing protein 4 THSD4 Tdark Non-IDG -0.62904 3.69 5
Methylcytosine dioxygenase TET2 TET2 Tbio Enzyme -3.26709 1777.6 290
Kinesin-like protein KIF3B KIF3B Tbio Non-IDG -1.37859 20.9 98
Hedgehog-interacting protein HHIP Tbio Non-IDG -1.83526 65.4 193
Serine/threonine-protein phosphatase 4 regulatory subunit 4 PPP4R4 Tdark Enzyme 0.24 0.55 29
Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2 GNG2 Tbio Non-IDG -0.97424 10.0 75
Ribonucleoside-diphosphate reductase subunit M2 B RRM2B Tbio Enzyme -1.91697 95.0 244