Development Level

Tbio 80 | 11,445
Tdark 19 | 6,588
Tchem 15 | 1,598
Tclin 9 | 613

Collection

Kinase: IDG Consortium (Target... 2 | 125
Ion Channel: IDG Consortium (T... 1 | 99

IMPC Phenotype

preweaning lethality, complete... 6 | 979
abnormal behavior 5 | 298
preweaning lethality, incomple... 5 | 499
cataract 3 | 92
decreased circulating HDL chol... 3 | 68
decreased circulating choleste... 3 | 93
decreased circulating serum al... 3 | 82
increased circulating alkaline... 3 | 122
increased circulating choleste... 3 | 66
increased lean body mass 3 | 172
abnormal embryo size 2 | 220
abnormal lens morphology 2 | 81
decreased blood urea nitrogen ... 2 | 51
decreased circulating calcium ... 2 | 36
decreased circulating glucose ... 2 | 126
decreased circulating triglyce... 2 | 79
decreased total body fat amoun... 2 | 207
hyperactivity 2 | 148
hypoactivity 2 | 132
increased circulating HDL chol... 2 | 80
increased circulating chloride... 2 | 41
increased mean corpuscular vol... 2 | 92
increased total body fat amoun... 2 | 134
abnormal bone mineralization 1 | 38
abnormal bone structure 1 | 187
abnormal cranium morphology 1 | 36
abnormal facial morphology 1 | 17
abnormal gait 1 | 69
abnormal head shape 1 | 10
abnormal lung morphology 1 | 26
abnormal outer ear morphology 1 | 3
abnormal retinal blood vessel ... 1 | 26
abnormal retinal vasculature m... 1 | 27
abnormal seminal vesicle morph... 1 | 114
abnormal skin morphology 1 | 50
abnormal sleep behavior 1 | 70
abnormal testis morphology 1 | 43
abnormal tooth morphology 1 | 24
absent startle reflex 1 | 24
anophthalmia 1 | 33
decreased body weight 1 | 161
decreased bone mineral content 1 | 151
decreased bone mineral density 1 | 126
decreased caudal vertebrae num... 1 | 53
decreased circulating LDL chol... 1 | 38
decreased circulating alkaline... 1 | 46
decreased circulating iron lev... 1 | 32
decreased circulating sodium l... 1 | 22
decreased circulating total pr... 1 | 49
decreased circulating unsatura... 1 | 2
decreased erythrocyte cell num... 1 | 62
decreased exploration in new e... 1 | 11
decreased grip strength 1 | 116
decreased heart left ventricle... 1 | 28
decreased mean corpuscular vol... 1 | 79
decreased prepulse inhibition 1 | 82
decreased threshold for audito... 1 | 26
decreased vertical activity 1 | 208
embryonic lethality prior to o... 1 | 239
embryonic lethality prior to t... 1 | 278
enlarged heart 1 | 210
impaired glucose tolerance 1 | 75
improved glucose tolerance 1 | 79
increased blood uric acid leve... 1 | 5
increased body length 1 | 32
increased bone mineral content 1 | 108
increased bone mineral density 1 | 72
increased circulating LDL chol... 1 | 13
increased circulating amylase ... 1 | 25
increased circulating bilirubi... 1 | 16
increased circulating free fat... 1 | 20
increased circulating iron lev... 1 | 30
increased circulating sodium l... 1 | 71
increased circulating triglyce... 1 | 42
increased circulating unsatura... 1 | 1
increased erythrocyte cell num... 1 | 39
increased exploration in new e... 1 | 8
increased granulocyte number 1 | 1
increased heart rate 1 | 23
increased hematocrit 1 | 46
increased leukocyte cell numbe... 1 | 47
increased mean corpuscular hem... 1 | 96
increased mean corpuscular hem... 1 | 36
increased prepulse inhibition 1 | 32
increased startle reflex 1 | 112
increased total retina thickne... 1 | 4
long tibia 1 | 25
microphthalmia 1 | 26
prenatal lethality prior to he... 1 | 87
small testis 1 | 58
thin ventricular wall 1 | 24
thrombocytosis 1 | 27
tremors 1 | 39

Disease

Carcinoma 98 | 11,493
osteosarcoma 63 | 7,950
ovarian cancer 52 | 8,520
psoriasis 51 | 6,694
medulloblastoma, large-cell 40 | 6,241
Cardiovascular system disease 33 | 246
lung cancer 33 | 4,740
glioblastoma 32 | 5,792
Lipid metabolism disorder 28 | 114
malignant mesothelioma 28 | 3,232
atypical teratoid / rhabdoid tumor 27 | 5,112
diabetes mellitus 27 | 1,728
group 3 medulloblastoma 25 | 4,104
intraductal papillary-mucinous carcinoma (IPMC) 25 | 2,989
ependymoma 24 | 4,679
Kidney cancer 23 | 2,613
adult high grade glioma 22 | 3,801
invasive ductal carcinoma 22 | 2,951
pancreatic ductal adenocarcinoma liver metastasis 22 | 1,962
Atherosclerosis 21 | 291
Cancer 21 | 2,499
Coronary artery disease 21 | 268
intraductal papillary-mucinous adenoma (IPMA) 21 | 2,955
Breast cancer 20 | 3,578
intraductal papillary-mucinous neoplasm (IPMN) 20 | 3,291
lung adenocarcinoma 19 | 2,716
ductal carcinoma in situ 18 | 1,745
pancreatic cancer 18 | 2,398
Obesity 17 | 678
tuberculosis 17 | 2,010
ulcerative colitis 17 | 1,819
Autosomal recessive predisposition 16 | 1,442
primitive neuroectodermal tumor 16 | 3,035
Pick disease 15 | 1,894
Rheumatoid arthritis 15 | 1,191
astrocytic glioma 15 | 2,597
interstitial cystitis 15 | 2,312
lung carcinoma 15 | 2,843
oligodendroglioma 15 | 2,850
Schizophrenia 14 | 1,160
Type 2 diabetes mellitus 14 | 272
non-small cell lung cancer 14 | 2,890
Alzheimer's disease 13 | 658
Fatty liver disease 13 | 103
spina bifida 13 | 1,074
Anemia 12 | 365
astrocytoma 12 | 1,146
breast carcinoma 12 | 1,638
group 4 medulloblastoma 12 | 1,855
Astrocytoma, Pilocytic 11 | 3,081
Hypercholesterolemia 11 | 44
Intellectual disability 11 | 1,016
Liver cancer 11 | 604
Liver disease 11 | 237
Vascular disease 11 | 319
subependymal giant cell astrocytoma 11 | 2,287
Dull intelligence 10 | 645
Low intelligence 10 | 645
Mental Retardation 10 | 645
Mental deficiency 10 | 645
Metabolic syndrome X 10 | 52
Poor school performance 10 | 645
Sickle Cell Anemia 10 | 53
acute quadriplegic myopathy 10 | 1,158
adrenocortical carcinoma 10 | 1,428
cystic fibrosis 10 | 1,696
Bilirubin metabolic disorder 9 | 41
Hepatomegaly 9 | 285
Hyperlipidemia 9 | 43
Myocardial Infarction 9 | 151
Short stature 9 | 531
active Crohn's disease 9 | 922
colon cancer 9 | 1,478
juvenile dermatomyositis 9 | 1,187
Atopic dermatitis 8 | 952
Cerebrovascular disease 8 | 238
Chemical and Drug Induced Liver Injury 8 | 195
Dyslipidemias 8 | 27
Epilepsy 8 | 792
Heart disease 8 | 306
Hypercholesterolemia, Familial 8 | 23
active ulcerative colitis 8 | 764
mucosa-associated lymphoid tissue lymphoma 8 | 484
Bipolar Disorder 7 | 666
Colorectal Neoplasms 7 | 243
Coronary Disease 7 | 25
Kidney disease 7 | 430
Muscle hypotonia 7 | 571
Pericholangitis 7 | 8
dermatomyositis 7 | 966
pancreatic carcinoma 7 | 562
Cognitive delay 6 | 608
Mental and motor retardation 6 | 608
Multiple myeloma 6 | 1,332
Prostatic Neoplasms 6 | 495
acute myeloid leukemia 6 | 783
autosomal dominant Emery-Dreifuss muscular dystrophy 6 | 510
cutaneous lupus erythematosus 6 | 1,057
esophageal adenocarcinoma 6 | 737
non diabetic and post-ischemic heart failure 6 | 200

Tissue

Digestive Tract 118 | 17,369
Liver and Pancreas 117 | 16,750
Skin and soft tissues 117 | 17,230
Endocrine System 115 | 18,159
Urinary Tract 113 | 16,678
Female tissues 112 | 17,400
Male tissues 111 | 17,142
Blood and immune system 108 | 16,909
Nervous System 106 | 16,725
Respiratory system 104 | 16,393
Cardiovascular System 95 | 15,192

Target Family

Non-IDG 61 | 12,091
Enzyme 33 | 4,145
Transcription Factor 8 | 1,400
Transporter 7 | 473
Kinase 5 | 634
Ion Channel 3 | 344
Nuclear Receptor 3 | 48
Epigenetic 2 | 242
GPCR 1 | 408

GWAS Trait

Cholesterol, total 123 | 123
Obesity-related traits 569 | 569
Schizophrenia 533 | 533
Breast cancer 492 | 492
Body mass index 379 | 379
Height 369 | 369
Coronary artery disease 367 | 367
Blood protein levels 351 | 351
Post bronchodilator FEV1-FVC r... 308 | 308
Mean corpuscular volume 283 | 283
Platelet count 275 | 275
Intelligence (multi-trait anal... 267 | 267
Mean platelet volume 253 | 253
IgG glycosylation 250 | 250
Mean corpuscular hemoglobin 238 | 238
Inflammatory bowel disease 235 | 235
Plateletcrit 227 | 227
Crohn's disease 215 | 215
Type 2 diabetes 210 | 210
Red blood cell count 191 | 191
Monocyte count 183 | 183
Red cell distribution width 182 | 182
Eosinophil counts 180 | 180
Neuroticism 180 | 180
Platelet distribution width 174 | 174
Monocyte percentage of white c... 173 | 173
Post bronchodilator FEV1 173 | 173
Sum eosinophil basophil counts 173 | 173
White blood cell count 172 | 172
3-hydroxy-1-methylpropylmercap... 166 | 166
Eosinophil percentage of granu... 163 | 163
Eosinophil percentage of white... 163 | 163
Reticulocyte fraction of red c... 163 | 163
Ulcerative colitis 163 | 163
Granulocyte percentage of myel... 162 | 162
Itch intensity from mosquito b... 162 | 162
Systemic lupus erythematosus 159 | 159
High light scatter reticulocyt... 158 | 158
Lymphocyte counts 158 | 158
Reticulocyte count 158 | 158
Blood metabolite levels 157 | 157
Neutrophil count 154 | 154
High light scatter reticulocyt... 153 | 153
Neutrophil percentage of granu... 153 | 153
3-hydroxypropylmercapturic aci... 150 | 150
Tonsillectomy 149 | 149
Diastolic blood pressure 144 | 144
Sum basophil neutrophil counts 140 | 140
Autism spectrum disorder or sc... 134 | 134
Myeloid white cell count 133 | 133
Granulocyte count 132 | 132
Sum neutrophil eosinophil coun... 129 | 129
Colorectal cancer 126 | 126
Alzheimer disease and age of o... 124 | 124
Multiple sclerosis 124 | 124
Night sleep phenotypes 123 | 123
Lung cancer 122 | 122
Lymphocyte percentage of white... 122 | 122
Menarche (age at onset) 122 | 122
Neutrophil percentage of white... 121 | 121
Rheumatoid arthritis 121 | 121
Systolic blood pressure 120 | 120
Immature fraction of reticuloc... 118 | 118
Diisocyanate-induced asthma 116 | 116
HDL cholesterol 116 | 116
Allergic disease (asthma, hay ... 115 | 115
Educational attainment (years ... 114 | 114
Hematocrit 113 | 113
Hemoglobin concentration 112 | 112
LDL cholesterol 110 | 110
QT interval 110 | 110
Waist circumference adjusted f... 110 | 110
Mosquito bite size 107 | 107
Asthma 106 | 106
Lobe attachment (rater-scored ... 103 | 103
Peripheral arterial disease (t... 101 | 101
Pulse pressure 97 | 97
Bipolar disorder 94 | 94
Major depressive disorder 94 | 94
Prostate cancer 92 | 92
Parkinson's disease 90 | 90
Hip circumference adjusted for... 89 | 89
Metabolite levels 87 | 87
Triglycerides 87 | 87
Colonoscopy-negative controls ... 85 | 85
Mean corpuscular hemoglobin co... 85 | 85
Itch intensity from mosquito b... 84 | 84
Bipolar disorder and schizophr... 83 | 83
Resting heart rate 82 | 82
Macrophage inflammatory protei... 81 | 81
Migraine 81 | 81
Waist-to-hip ratio adjusted fo... 81 | 81
PR interval in Tripanosoma cru... 80 | 80
Cognitive performance 79 | 79
Glomerular filtration rate (cr... 78 | 78
Late-onset Alzheimer's disease 78 | 78
Waist circumference adjusted f... 75 | 75
Tuberculosis 73 | 73
Type 1 diabetes 73 | 73
Morning vs. evening chronotype 72 | 72

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
CKLF-like MARVEL transmembrane domain-containing protein 6 CMTM6 Tdark Non-IDG -0.56950 2.80 85
ATP-binding cassette sub-family A member 10 ABCA10 Tdark Transporter -0.25772 2.27 36
Glycerol-3-phosphate acyltransferase 1, mitochondrial GPAM Tbio Enzyme -1.93041 83.4 177
Pleckstrin homology-like domain family B member 1 PHLDB1 Tbio Non-IDG -0.86968 6.63 56
Uncharacterized protein C7orf50 C7orf50 Tdark Non-IDG 0.48 0.33 87
Fatty acid desaturase 2 FADS2 Tbio Enzyme -2.55411 349.6 135
Tyrosine-protein kinase FRK FRK Tchem Kinase -1.68365 49.2 394
Zinc finger protein 329 ZNF329 Tdark Transcription Factor 0.30 0.50 119
Zinc finger protein Gfi-1 GFI1 Tbio Transcription Factor -2.20783 172.7 176
Niemann-Pick C1-like protein 1 NPC1L1 Tclin Non-IDG -2.33312 222.7 139