Development Level

Tbio 19 | 11,445
Tchem 1 | 1,598
Tdark 1 | 6,588

Collection

GPCR: IDG Consortium (Targets) 1 | 126
Kinase: IDG Consortium (Target... 1 | 125

IMPC Phenotype

decreased circulating LDL chol... 2 | 38
hyperactivity 2 | 148
preweaning lethality, complete... 2 | 979
abnormal bone structure 1 | 187
abnormal sleep behavior 1 | 70
decreased bone mineral content 1 | 151
decreased circulating HDL chol... 1 | 68
decreased circulating alanine ... 1 | 47
decreased circulating aspartat... 1 | 34
decreased circulating choleste... 1 | 93
decreased circulating iron lev... 1 | 32
decreased heart weight 1 | 27
decreased lactate dehydrogenas... 1 | 16
increased vertical activity 1 | 24

Disease

Carcinoma 16 | 11,493
Acquired metabolic disease 12 | 336
ovarian cancer 11 | 8,520
atypical teratoid / rhabdoid tumor 10 | 5,112
osteosarcoma 10 | 7,950
ependymoma 9 | 4,679
Obesity 8 | 678
glioblastoma 8 | 5,792
medulloblastoma, large-cell 8 | 6,241
psoriasis 8 | 6,694
Astrocytoma, Pilocytic 7 | 3,081
adult high grade glioma 7 | 3,801
group 3 medulloblastoma 7 | 4,104
lung cancer 7 | 4,740
Breast cancer 6 | 3,578
interstitial cystitis 6 | 2,312
Body Weight 4 | 14
Pick disease 4 | 1,894
Schizophrenia 4 | 1,160
intraductal papillary-mucinous carcinoma (IPMC) 4 | 2,989
intraductal papillary-mucinous neoplasm (IPMN) 4 | 3,291
lung adenocarcinoma 4 | 2,716
malignant mesothelioma 4 | 3,232
subependymal giant cell astrocytoma 4 | 2,287
Alcoholic Intoxication, Chronic 3 | 289
Blepharoptosis 3 | 231
Kidney cancer 3 | 2,613
Mood Disorders 3 | 184
astrocytic glioma 3 | 2,597
astrocytoma 3 | 1,146
cystic fibrosis 3 | 1,696
group 4 medulloblastoma 3 | 1,855
intraductal papillary-mucinous adenoma (IPMA) 3 | 2,955
lung carcinoma 3 | 2,843
oligodendroglioma 3 | 2,850
pancreatic cancer 3 | 2,398
pancreatic ductal adenocarcinoma liver metastasis 3 | 1,962
pituitary cancer 3 | 1,972
spina bifida 3 | 1,074
Bilateral fifth finger clinodactyly 2 | 110
Bipolar Disorder 2 | 666
Breast Neoplasms 2 | 445
Cancer 2 | 2,499
Cataract 2 | 297
Curvature of little finger 2 | 110
Depressive disorder 2 | 409
Diabetes Mellitus, Type 2 2 | 142
Downward slant of palpebral fissure 2 | 158
Epilepsy 2 | 792
Everted lower lip vermilion 2 | 54
Glaucoma 2 | 239
Kidney disease 2 | 430
Lens Opacities 2 | 231
Low Vision 2 | 174
Low set ears 2 | 181
Mental Depression 2 | 333
Multiple myeloma 2 | 1,332
Nystagmus 2 | 317
Obesity, Morbid 2 | 7
Osteoarthritis 2 | 184
Parkinson's disease 2 | 392
Protruding lower lip 2 | 54
Retinal Degeneration 2 | 106
Rheumatoid arthritis 2 | 1,191
Short stature 2 | 531
Type 2 diabetes mellitus 2 | 272
Visual Impairment 2 | 174
Waldenstrons macroglobulinemia 2 | 765
active Crohn's disease 2 | 922
aldosterone-producing adenoma 2 | 665
cutaneous lupus erythematosus 2 | 1,057
diabetes mellitus 2 | 1,728
ductal carcinoma in situ 2 | 1,745
gastric carcinoma 2 | 807
invasive ductal carcinoma 2 | 2,951
juvenile dermatomyositis 2 | 1,187
non primary Sjogren syndrome sicca 2 | 891
pediatric high grade glioma 2 | 1,064
primitive neuroectodermal tumor 2 | 3,035
tuberculosis 2 | 2,010
Abnormal color vision 1 | 31
Acquired flat foot 1 | 72
Blastic phase chronic myeloid leukemia 1 | 58
Bushy eyebrows 1 | 49
Cardiovascular Abnormalities 1 | 31
Chronic Myelocytic Leukemia Accelerated Phase 1 | 59
Color vision defect 1 | 33
Color vision defect, severe 1 | 31
Diabetic retinopathy 1 | 56
Flatfoot 1 | 73
Glomerulonephritis 1 | 46
Hematuria 1 | 36
Hypoplastic toenails 1 | 22
Mild Mental Retardation 1 | 70
Nystagmus, continuous pendular 1 | 14
Pendular Nystagmus 1 | 14
Retinitis pigmentosa 59 1 | 11
Riley-Day syndrome 1 | 11
Thick vermilion border 1 | 25
Thick, flared eyebrows 1 | 41

Tissue

Digestive Tract 21 | 17,369
Endocrine System 21 | 18,159
Female tissues 21 | 17,400
Nervous System 21 | 16,725
Skin and soft tissues 21 | 17,230
Blood and immune system 20 | 16,909
Respiratory system 20 | 16,393
Cardiovascular System 19 | 15,192
Male tissues 19 | 17,142
Urinary Tract 19 | 16,678
Liver and Pancreas 18 | 16,750

Target Family

Non-IDG 8 | 12,091
Enzyme 6 | 4,145
Kinase 2 | 634
Transcription Factor 2 | 1,400
Epigenetic 1 | 242
GPCR 1 | 408
Transporter 1 | 473

GWAS Trait

Childhood body mass index 21 | 21
Obesity-related traits 569 | 569
Schizophrenia 533 | 533
Breast cancer 492 | 492
Body mass index 379 | 379
Height 369 | 369
Coronary artery disease 367 | 367
Blood protein levels 351 | 351
Post bronchodilator FEV1-FVC r... 308 | 308
Mean corpuscular volume 283 | 283
Platelet count 275 | 275
Intelligence (multi-trait anal... 267 | 267
Mean platelet volume 253 | 253
IgG glycosylation 250 | 250
Mean corpuscular hemoglobin 238 | 238
Inflammatory bowel disease 235 | 235
Plateletcrit 227 | 227
Crohn's disease 215 | 215
Type 2 diabetes 210 | 210
Red blood cell count 191 | 191
Monocyte count 183 | 183
Red cell distribution width 182 | 182
Eosinophil counts 180 | 180
Neuroticism 180 | 180
Platelet distribution width 174 | 174
Monocyte percentage of white c... 173 | 173
Post bronchodilator FEV1 173 | 173
Sum eosinophil basophil counts 173 | 173
White blood cell count 172 | 172
3-hydroxy-1-methylpropylmercap... 166 | 166
Eosinophil percentage of granu... 163 | 163
Eosinophil percentage of white... 163 | 163
Reticulocyte fraction of red c... 163 | 163
Ulcerative colitis 163 | 163
Granulocyte percentage of myel... 162 | 162
Itch intensity from mosquito b... 162 | 162
Systemic lupus erythematosus 159 | 159
High light scatter reticulocyt... 158 | 158
Lymphocyte counts 158 | 158
Reticulocyte count 158 | 158
Blood metabolite levels 157 | 157
Neutrophil count 154 | 154
High light scatter reticulocyt... 153 | 153
Neutrophil percentage of granu... 153 | 153
3-hydroxypropylmercapturic aci... 150 | 150
Tonsillectomy 149 | 149
Diastolic blood pressure 144 | 144
Sum basophil neutrophil counts 140 | 140
Autism spectrum disorder or sc... 134 | 134
Myeloid white cell count 133 | 133
Granulocyte count 132 | 132
Sum neutrophil eosinophil coun... 129 | 129
Colorectal cancer 126 | 126
Alzheimer disease and age of o... 124 | 124
Multiple sclerosis 124 | 124
Cholesterol, total 123 | 123
Night sleep phenotypes 123 | 123
Lung cancer 122 | 122
Lymphocyte percentage of white... 122 | 122
Menarche (age at onset) 122 | 122
Neutrophil percentage of white... 121 | 121
Rheumatoid arthritis 121 | 121
Systolic blood pressure 120 | 120
Immature fraction of reticuloc... 118 | 118
Diisocyanate-induced asthma 116 | 116
HDL cholesterol 116 | 116
Allergic disease (asthma, hay ... 115 | 115
Educational attainment (years ... 114 | 114
Hematocrit 113 | 113
Hemoglobin concentration 112 | 112
LDL cholesterol 110 | 110
QT interval 110 | 110
Waist circumference adjusted f... 110 | 110
Mosquito bite size 107 | 107
Asthma 106 | 106
Lobe attachment (rater-scored ... 103 | 103
Peripheral arterial disease (t... 101 | 101
Pulse pressure 97 | 97
Bipolar disorder 94 | 94
Major depressive disorder 94 | 94
Prostate cancer 92 | 92
Parkinson's disease 90 | 90
Hip circumference adjusted for... 89 | 89
Metabolite levels 87 | 87
Triglycerides 87 | 87
Colonoscopy-negative controls ... 85 | 85
Mean corpuscular hemoglobin co... 85 | 85
Itch intensity from mosquito b... 84 | 84
Bipolar disorder and schizophr... 83 | 83
Resting heart rate 82 | 82
Macrophage inflammatory protei... 81 | 81
Migraine 81 | 81
Waist-to-hip ratio adjusted fo... 81 | 81
PR interval in Tripanosoma cru... 80 | 80
Cognitive performance 79 | 79
Glomerular filtration rate (cr... 78 | 78
Late-onset Alzheimer's disease 78 | 78
Waist circumference adjusted f... 75 | 75
Tuberculosis 73 | 73
Type 1 diabetes 73 | 73
Morning vs. evening chronotype 72 | 72

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Brain-derived neurotrophic factor BDNF Tbio Non-IDG -4.00507 10701.6 723
Alpha-ketoglutarate-dependent dioxygenase FTO FTO Tbio Enzyme -3.13021 1342.0 318
Protein lifeguard 2 FAIM2 Tbio Non-IDG -2.37264 234.7 176
Adenylate cyclase type 3 ADCY3 Tbio Enzyme -2.31593 204.4 82
LIM homeobox transcription factor 1-beta LMX1B Tbio Transcription Factor -2.24141 180.3 191
Constitutive coactivator of PPAR-gamma-like protein 1 FAM120A Tbio Non-IDG -2.04779 108.9 91
Zinc transporter ZIP8 SLC39A8 Tbio Transporter -1.80468 66.8 100
Elongator complex protein 3 ELP3 Tbio Epigenetic -1.75885 53.5 124
Transcription factor AP-2-beta TFAP2B Tbio Transcription Factor -1.74089 52.9 225
Ras-related protein Rab-27B RAB27B Tbio Enzyme -1.63479 44.7 179