Development Level

Tbio 17 | 11,445
Tdark 5 | 6,588

IMPC Phenotype

decreased circulating glucose ... 2 | 126
decreased total body fat amoun... 2 | 207
increased circulating alkaline... 2 | 122
abnormal bone structure 1 | 187
abnormal cranium morphology 1 | 36
abnormal maxilla morphology 1 | 17
abnormal pelvic girdle bone mo... 1 | 12
abnormal tooth morphology 1 | 24
abnormal vertebrae morphology 1 | 18
abnormal zygomatic bone morpho... 1 | 3
decreased body length 1 | 101
decreased bone mineral density 1 | 126
decreased caudal vertebrae num... 1 | 53
decreased circulating HDL chol... 1 | 68
decreased circulating choleste... 1 | 93
decreased circulating serum al... 1 | 82
decreased circulating sodium l... 1 | 22
decreased erythrocyte cell num... 1 | 62
decreased startle reflex 1 | 75
female infertility 1 | 60
improved glucose tolerance 1 | 79
increased circulating LDL chol... 1 | 13
increased circulating bilirubi... 1 | 16
increased circulating choleste... 1 | 66
increased circulating free fat... 1 | 20
increased circulating triglyce... 1 | 42
increased lean body mass 1 | 172
increased mean corpuscular hem... 1 | 36
increased startle reflex 1 | 112
increased total body fat amoun... 1 | 134
male infertility 1 | 123
preweaning lethality, incomple... 1 | 499
short tibia 1 | 97
small superior vagus ganglion 1 | 74
small testis 1 | 58
vertebral fusion 1 | 23

Disease

Carcinoma 18 | 11,493
ovarian cancer 12 | 8,520
psoriasis 12 | 6,694
adult high grade glioma 11 | 3,801
atypical teratoid / rhabdoid tumor 11 | 5,112
ependymoma 11 | 4,679
glioblastoma 11 | 5,792
medulloblastoma, large-cell 10 | 6,241
oligodendroglioma 10 | 2,850
osteosarcoma 10 | 7,950
group 3 medulloblastoma 9 | 4,104
Alzheimer's disease 8 | 658
Kidney cancer 8 | 2,613
Breast cancer 7 | 3,578
astrocytic glioma 7 | 2,597
malignant mesothelioma 7 | 3,232
intraductal papillary-mucinous neoplasm (IPMN) 6 | 3,291
Astrocytoma, Pilocytic 5 | 3,081
Cancer 5 | 2,499
group 4 medulloblastoma 5 | 1,855
intraductal papillary-mucinous carcinoma (IPMC) 5 | 2,989
lung cancer 5 | 4,740
subependymal giant cell astrocytoma 5 | 2,287
Obesity 4 | 678
Schizophrenia 4 | 1,160
interstitial cystitis 4 | 2,312
intraductal papillary-mucinous adenoma (IPMA) 4 | 2,955
invasive ductal carcinoma 4 | 2,951
lung adenocarcinoma 4 | 2,716
pancreatic cancer 4 | 2,398
pituitary cancer 4 | 1,972
primitive neuroectodermal tumor 4 | 3,035
Down syndrome 3 | 499
Kidney disease 3 | 430
Polycystic ovary syndrome 3 | 360
Rheumatoid arthritis 3 | 1,191
Type 1 diabetes mellitus 3 | 109
active ulcerative colitis 3 | 764
acute quadriplegic myopathy 3 | 1,158
adrenocortical carcinoma 3 | 1,428
diabetes mellitus 3 | 1,728
juvenile dermatomyositis 3 | 1,187
non primary Sjogren syndrome sicca 3 | 891
tuberculosis 3 | 2,010
ulcerative colitis 3 | 1,819
Acquired metabolic disease 2 | 336
Atherosclerosis 2 | 291
Autosomal recessive predisposition 2 | 1,442
Bipolar Disorder 2 | 666
Breast Neoplasms 2 | 445
Carcinoma, Renal Cell 2 | 124
Cell Transformation, Neoplastic 2 | 97
Chronic obstructive pulmonary disease 2 | 184
Coronary Disease 2 | 25
Coronary artery disease 2 | 268
Crohn's disease 2 | 321
Diabetes Mellitus, Non-Insulin-Dependent 2 | 145
Diabetes Mellitus, Type 2 2 | 142
Gastrointestinal system disease 2 | 54
Globe disease 2 | 67
Heart disease 2 | 306
Hyperglycemia 2 | 137
Hyperlipidemia 2 | 43
Hyperlipidemias 2 | 17
Hypertension 2 | 396
Lipid metabolism disorder 2 | 114
Liver Cirrhosis, Experimental 2 | 769
Liver cancer 2 | 604
Lung Neoplasms 2 | 232
Mammary Neoplasms 2 | 425
Neoplastic Cell Transformation 2 | 89
Pick disease 2 | 1,894
Prostatic Neoplasms 2 | 495
Renal Cell Carcinoma 2 | 214
Skin cancer 2 | 469
Type 2 diabetes mellitus 2 | 272
acute myeloid leukemia 2 | 783
astrocytoma 2 | 1,146
breast carcinoma 2 | 1,638
colon cancer 2 | 1,478
ductal carcinoma in situ 2 | 1,745
esophageal adenocarcinoma 2 | 737
facioscapulohumeral dystrophy 2 | 288
gastric carcinoma 2 | 807
medulloblastoma 2 | 720
nephrosclerosis 2 | 333
pancreatic ductal adenocarcinoma liver metastasis 2 | 1,962
posterior fossa group A ependymoma 2 | 468
spina bifida 2 | 1,074
Adenocarcinoma 1 | 122
Age related macular degeneration 1 | 72
Aphasia 1 | 26
Attention Deficit Disorder with Hyperactivity 1 | 21
Autism Spectrum Disorders 1 | 75
Diabetes Mellitus, Noninsulin-Dependent 1 | 31
Gestational diabetes 1 | 26
Macular degeneration 1 | 65
Precancerous Conditions 1 | 80
Thyroid cancer 1 | 36
Timothy syndrome 1 | 11

Tissue

Endocrine System 22 | 18,159
Nervous System 22 | 16,725
Digestive Tract 21 | 17,369
Male tissues 21 | 17,142
Skin and soft tissues 21 | 17,230
Female tissues 20 | 17,400
Liver and Pancreas 20 | 16,750
Urinary Tract 20 | 16,678
Blood and immune system 19 | 16,909
Cardiovascular System 18 | 15,192
Respiratory system 18 | 16,393

Target Family

Non-IDG 14 | 12,091
Enzyme 6 | 4,145
Transcription Factor 2 | 1,400

GWAS Trait

Cerebrospinal P-tau181p levels 22 | 22
Obesity-related traits 569 | 569
Schizophrenia 533 | 533
Breast cancer 492 | 492
Body mass index 379 | 379
Height 369 | 369
Coronary artery disease 367 | 367
Blood protein levels 351 | 351
Post bronchodilator FEV1-FVC r... 308 | 308
Mean corpuscular volume 283 | 283
Platelet count 275 | 275
Intelligence (multi-trait anal... 267 | 267
Mean platelet volume 253 | 253
IgG glycosylation 250 | 250
Mean corpuscular hemoglobin 238 | 238
Inflammatory bowel disease 235 | 235
Plateletcrit 227 | 227
Crohn's disease 215 | 215
Type 2 diabetes 210 | 210
Red blood cell count 191 | 191
Monocyte count 183 | 183
Red cell distribution width 182 | 182
Eosinophil counts 180 | 180
Neuroticism 180 | 180
Platelet distribution width 174 | 174
Monocyte percentage of white c... 173 | 173
Post bronchodilator FEV1 173 | 173
Sum eosinophil basophil counts 173 | 173
White blood cell count 172 | 172
3-hydroxy-1-methylpropylmercap... 166 | 166
Eosinophil percentage of granu... 163 | 163
Eosinophil percentage of white... 163 | 163
Reticulocyte fraction of red c... 163 | 163
Ulcerative colitis 163 | 163
Granulocyte percentage of myel... 162 | 162
Itch intensity from mosquito b... 162 | 162
Systemic lupus erythematosus 159 | 159
High light scatter reticulocyt... 158 | 158
Lymphocyte counts 158 | 158
Reticulocyte count 158 | 158
Blood metabolite levels 157 | 157
Neutrophil count 154 | 154
High light scatter reticulocyt... 153 | 153
Neutrophil percentage of granu... 153 | 153
3-hydroxypropylmercapturic aci... 150 | 150
Tonsillectomy 149 | 149
Diastolic blood pressure 144 | 144
Sum basophil neutrophil counts 140 | 140
Autism spectrum disorder or sc... 134 | 134
Myeloid white cell count 133 | 133
Granulocyte count 132 | 132
Sum neutrophil eosinophil coun... 129 | 129
Colorectal cancer 126 | 126
Alzheimer disease and age of o... 124 | 124
Multiple sclerosis 124 | 124
Cholesterol, total 123 | 123
Night sleep phenotypes 123 | 123
Lung cancer 122 | 122
Lymphocyte percentage of white... 122 | 122
Menarche (age at onset) 122 | 122
Neutrophil percentage of white... 121 | 121
Rheumatoid arthritis 121 | 121
Systolic blood pressure 120 | 120
Immature fraction of reticuloc... 118 | 118
Diisocyanate-induced asthma 116 | 116
HDL cholesterol 116 | 116
Allergic disease (asthma, hay ... 115 | 115
Educational attainment (years ... 114 | 114
Hematocrit 113 | 113
Hemoglobin concentration 112 | 112
LDL cholesterol 110 | 110
QT interval 110 | 110
Waist circumference adjusted f... 110 | 110
Mosquito bite size 107 | 107
Asthma 106 | 106
Lobe attachment (rater-scored ... 103 | 103
Peripheral arterial disease (t... 101 | 101
Pulse pressure 97 | 97
Bipolar disorder 94 | 94
Major depressive disorder 94 | 94
Prostate cancer 92 | 92
Parkinson's disease 90 | 90
Hip circumference adjusted for... 89 | 89
Metabolite levels 87 | 87
Triglycerides 87 | 87
Colonoscopy-negative controls ... 85 | 85
Mean corpuscular hemoglobin co... 85 | 85
Itch intensity from mosquito b... 84 | 84
Bipolar disorder and schizophr... 83 | 83
Resting heart rate 82 | 82
Macrophage inflammatory protei... 81 | 81
Migraine 81 | 81
Waist-to-hip ratio adjusted fo... 81 | 81
PR interval in Tripanosoma cru... 80 | 80
Cognitive performance 79 | 79
Glomerular filtration rate (cr... 78 | 78
Late-onset Alzheimer's disease 78 | 78
Waist circumference adjusted f... 75 | 75
Tuberculosis 73 | 73
Type 1 diabetes 73 | 73
Morning vs. evening chronotype 72 | 72

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Myotubularin-related protein 3 MTMR3 Tbio Enzyme -1.05980 10.7 33
Dynein assembly factor 5, axonemal DNAAF5 Tbio Non-IDG -0.07918 1.36 54
Palmitoyltransferase ZDHHC22 ZDHHC22 Tdark Enzyme 0.10 0.33 17
Zinc finger protein GLIS3 GLIS3 Tbio Transcription Factor -1.36377 28.8 63
Zinc finger protein 536 ZNF536 Tdark Transcription Factor -0.20702 1.30 75
Probable ATP-dependent RNA helicase DDX49 DDX49 Tdark Enzyme 0.39 0.08 93
Interleukin-34 IL34 Tbio Non-IDG -1.81880 73.0 256
Alkylglycerol monooxygenase AGMO Tbio Enzyme -1.32795 21.3 47
Protocadherin-8 PCDH8 Tbio Non-IDG -2.22282 170.9 95
Tetratricopeptide repeat protein 28 TTC28 Tdark Non-IDG -0.50526 3.76 3