Development Level

Tbio 5 | 11,445

Collection

Kinase: IDG Consortium (Target... 1 | 125

IMPC Phenotype

abnormal clavicle morphology 1 | 6
abnormal eyelid morphology 1 | 7
abnormal femur morphology 1 | 14
abnormal fibula morphology 1 | 2
abnormal gait 1 | 69
abnormal humerus morphology 1 | 11
abnormal joint morphology 1 | 23
abnormal locomotor behavior 1 | 24
abnormal mandible morphology 1 | 2
abnormal maxilla morphology 1 | 17
abnormal pelvic girdle bone mo... 1 | 12
abnormal radius morphology 1 | 8
abnormal rib morphology 1 | 10
abnormal snout morphology 1 | 23
abnormal tibia morphology 1 | 14
abnormal tooth morphology 1 | 24
abnormal ulna morphology 1 | 8
abnormal vertebrae morphology 1 | 18
abnormal zygomatic bone morpho... 1 | 3
absent teeth 1 | 3
decreased basophil cell number 1 | 16
decreased circulating alkaline... 1 | 46
decreased eosinophil cell numb... 1 | 24
decreased lean body mass 1 | 135
decreased lymphocyte cell numb... 1 | 83
increased bone mineral content 1 | 108
increased bone mineral density 1 | 72
increased circulating HDL chol... 1 | 80
increased circulating aspartat... 1 | 15
increased circulating calcium ... 1 | 34
increased circulating choleste... 1 | 66
increased neutrophil cell numb... 1 | 46
increased red blood cell distr... 1 | 34
increased spleen weight 1 | 10
preweaning lethality, complete... 1 | 979
short tibia 1 | 97
small thymus 1 | 16
thrombocytopenia 1 | 56

Disease

Carcinoma 5 | 11,493
medulloblastoma, large-cell 4 | 6,241
Corneal disease 3 | 31
Glaucoma 3 | 239
Keratoconus 3 | 113
osteosarcoma 3 | 7,950
ovarian cancer 3 | 8,520
psoriasis 3 | 6,694
Astrocytoma, Pilocytic 2 | 3,081
Breast cancer 2 | 3,578
Congenital diaphragmatic hernia 2 | 67
Ehlers-Danlos syndrome 2 | 43
Kidney cancer 2 | 2,613
Liver cancer 2 | 604
Myopia 2 | 176
atypical teratoid / rhabdoid tumor 2 | 5,112
breast carcinoma 2 | 1,638
ependymoma 2 | 4,679
glioblastoma 2 | 5,792
interstitial cystitis 2 | 2,312
intraductal papillary-mucinous carcinoma (IPMC) 2 | 2,989
lung adenocarcinoma 2 | 2,716
lung cancer 2 | 4,740
primitive neuroectodermal tumor 2 | 3,035
Absence of eyebrows 1 | 31
Acne 1 | 52
Acquired flat foot 1 | 72
Alveolar rhabdomyosarcoma 1 | 7
Aneurysm, Dissecting 1 | 8
Animal Mammary Neoplasms 1 | 136
Aortic root dilatation 1 | 11
Aplasia/Hypoplasia of the eyebrow 1 | 31
Arteriovenous fistulas of celiac and mesenteric vessels 1 | 3
Atrophic scar 1 | 18
Autoimmune lymphoproliferative syndrome type 2B 1 | 9
Bat ear 1 | 3
Bladder Diverticulum 1 | 15
Blue sclera 1 | 32
Brittle cornea syndrome 1 | 4
Bunion 1 | 26
Cigarette-paper scars 1 | 4
Congenital pectus carinatum 1 | 52
Degenerative polyarthritis 1 | 115
Dental caries 1 | 164
Dilatation of aorta 1 | 9
Ecchymosis 1 | 66
Ectopia Lentis 1 | 17
Ehlers-Danlos syndrome classic type 1 | 3
Ehlers-Danlos syndrome type 1 1 | 3
Ehlers-Danlos syndrome type 2 1 | 3
Ehlers-Danlos syndrome, classic type 1 | 3
Fatty liver disease 1 | 103
Flat face 1 | 52
Flatfoot 1 | 73
Fragile skin 1 | 18
Genu recurvatum 1 | 12
Hallux Valgus 1 | 26
Hernia, Femoral 1 | 7
Hyperglycemia 1 | 137
Hyperinsulinism 1 | 133
Hypertension, Pulmonary 1 | 37
Hypokalemia 1 | 52
Increased tendency to bruise 1 | 66
Infantile muscular hypotonia 1 | 12
Irregularly spaced teeth 1 | 3
Keloid 1 | 37
Leukemia, Myelocytic, Acute 1 | 120
Leukemia, Myeloid, Acute 1 | 105
Mammary Neoplasms, Animal 1 | 136
Mammary Neoplasms, Experimental 1 | 154
Melanocytic nevus 1 | 43
Mitral Valve Prolapse Syndrome 1 | 39
Molluscoid pseudotumors 1 | 5
Muscular atrophy 1 | 71
Narrow maxilla 1 | 3
Noncancerous mole 1 | 28
Osteopetrosis 1 | 43
Pneumothorax 1 | 23
Poor wound healing 1 | 8
Premature Birth 1 | 77
Premature birth following premature rupture of fetal membranes 1 | 3
Premature birth of newborn 1 | 67
Prominent eyes 1 | 96
Prominent globes 1 | 96
Protruding eyes 1 | 96
Respiratory Insufficiency 1 | 132
Respiratory function loss 1 | 121
Rotting teeth 1 | 73
Skin Abnormalities 1 | 37
Soft skin 1 | 17
Sparse or absent eyebrows 1 | 31
Sparse/absent eyebrows 1 | 31
Sprengel deformity 1 | 16
Telangiectasia of the skin 1 | 39
Telecanthus 1 | 62
Varicosity 1 | 12
Velvety skin 1 | 17
X-linked cerebral adrenoleukodystrophy 1 | 116
interstitial lung disease 1 | 298
nail-patella syndrome 1 | 16

Tissue

Blood and immune system 5 | 16,909
Digestive Tract 5 | 17,369
Endocrine System 5 | 18,159
Female tissues 5 | 17,400
Liver and Pancreas 5 | 16,750
Male tissues 5 | 17,142
Nervous System 5 | 16,725
Respiratory system 5 | 16,393
Skin and soft tissues 5 | 17,230
Urinary Tract 5 | 16,678
Cardiovascular System 4 | 15,192

Target Family

Non-IDG 2 | 12,091
Transcription Factor 2 | 1,400
Kinase 1 | 634

GWAS Trait

Central corneal thickness 5 | 5
Obesity-related traits 569 | 569
Schizophrenia 533 | 533
Breast cancer 492 | 492
Body mass index 379 | 379
Height 369 | 369
Coronary artery disease 367 | 367
Blood protein levels 351 | 351
Post bronchodilator FEV1-FVC r... 308 | 308
Mean corpuscular volume 283 | 283
Platelet count 275 | 275
Intelligence (multi-trait anal... 267 | 267
Mean platelet volume 253 | 253
IgG glycosylation 250 | 250
Mean corpuscular hemoglobin 238 | 238
Inflammatory bowel disease 235 | 235
Plateletcrit 227 | 227
Crohn's disease 215 | 215
Type 2 diabetes 210 | 210
Red blood cell count 191 | 191
Monocyte count 183 | 183
Red cell distribution width 182 | 182
Eosinophil counts 180 | 180
Neuroticism 180 | 180
Platelet distribution width 174 | 174
Monocyte percentage of white c... 173 | 173
Post bronchodilator FEV1 173 | 173
Sum eosinophil basophil counts 173 | 173
White blood cell count 172 | 172
3-hydroxy-1-methylpropylmercap... 166 | 166
Eosinophil percentage of granu... 163 | 163
Eosinophil percentage of white... 163 | 163
Reticulocyte fraction of red c... 163 | 163
Ulcerative colitis 163 | 163
Granulocyte percentage of myel... 162 | 162
Itch intensity from mosquito b... 162 | 162
Systemic lupus erythematosus 159 | 159
High light scatter reticulocyt... 158 | 158
Lymphocyte counts 158 | 158
Reticulocyte count 158 | 158
Blood metabolite levels 157 | 157
Neutrophil count 154 | 154
High light scatter reticulocyt... 153 | 153
Neutrophil percentage of granu... 153 | 153
3-hydroxypropylmercapturic aci... 150 | 150
Tonsillectomy 149 | 149
Diastolic blood pressure 144 | 144
Sum basophil neutrophil counts 140 | 140
Autism spectrum disorder or sc... 134 | 134
Myeloid white cell count 133 | 133
Granulocyte count 132 | 132
Sum neutrophil eosinophil coun... 129 | 129
Colorectal cancer 126 | 126
Alzheimer disease and age of o... 124 | 124
Multiple sclerosis 124 | 124
Cholesterol, total 123 | 123
Night sleep phenotypes 123 | 123
Lung cancer 122 | 122
Lymphocyte percentage of white... 122 | 122
Menarche (age at onset) 122 | 122
Neutrophil percentage of white... 121 | 121
Rheumatoid arthritis 121 | 121
Systolic blood pressure 120 | 120
Immature fraction of reticuloc... 118 | 118
Diisocyanate-induced asthma 116 | 116
HDL cholesterol 116 | 116
Allergic disease (asthma, hay ... 115 | 115
Educational attainment (years ... 114 | 114
Hematocrit 113 | 113
Hemoglobin concentration 112 | 112
LDL cholesterol 110 | 110
QT interval 110 | 110
Waist circumference adjusted f... 110 | 110
Mosquito bite size 107 | 107
Asthma 106 | 106
Lobe attachment (rater-scored ... 103 | 103
Peripheral arterial disease (t... 101 | 101
Pulse pressure 97 | 97
Bipolar disorder 94 | 94
Major depressive disorder 94 | 94
Prostate cancer 92 | 92
Parkinson's disease 90 | 90
Hip circumference adjusted for... 89 | 89
Metabolite levels 87 | 87
Triglycerides 87 | 87
Colonoscopy-negative controls ... 85 | 85
Mean corpuscular hemoglobin co... 85 | 85
Itch intensity from mosquito b... 84 | 84
Bipolar disorder and schizophr... 83 | 83
Resting heart rate 82 | 82
Macrophage inflammatory protei... 81 | 81
Migraine 81 | 81
Waist-to-hip ratio adjusted fo... 81 | 81
PR interval in Tripanosoma cru... 80 | 80
Cognitive performance 79 | 79
Glomerular filtration rate (cr... 78 | 78
Late-onset Alzheimer's disease 78 | 78
Waist circumference adjusted f... 75 | 75
Tuberculosis 73 | 73
Type 1 diabetes 73 | 73
Morning vs. evening chronotype 72 | 72

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Forkhead box protein O1 FOXO1 Tbio Transcription Factor -3.05358 1143.3 1478
Protein Wnt-7b WNT7B Tbio Non-IDG -1.76807 52.2 46
Leucine-rich repeat serine/threonine-protein kinase 1 LRRK1 Tbio Kinase -1.33128 18.1 134
Collagen alpha-1(V) chain COL5A1 Tbio Non-IDG -2.07285 114.2 274
Zinc finger protein 469 ZNF469 Tbio Transcription Factor -1.25718 17.6 3