Development Level

Tbio 39 | 11,445
Tchem 12 | 1,598
Tdark 6 | 6,588
Tclin 2 | 613

Collection

Kinase: IDG Consortium (Target... 2 | 125

IMPC Phenotype

abnormal bone structure 2 | 187
decreased bone mineral content 2 | 151
decreased bone mineral density 2 | 126
decreased fasted circulating g... 2 | 65
increased hemoglobin content 2 | 45
increased mean corpuscular hem... 2 | 96
male infertility 2 | 123
preweaning lethality, complete... 2 | 979
short tibia 2 | 97
abnormal behavioral response t... 1 | 66
abnormal eye anterior chamber ... 1 | 9
abnormal heart morphology 1 | 162
abnormal locomotor behavior 1 | 24
abnormal retina morphology 1 | 71
abnormal testis morphology 1 | 43
cardiovascular system phenotyp... 1 | 36
decreased circulating creatini... 1 | 39
decreased circulating glucose ... 1 | 126
decreased circulating insulin ... 1 | 76
decreased large unstained cell... 1 | 11
decreased lean body mass 1 | 135
decreased startle reflex 1 | 75
decreased vertical activity 1 | 208
enlarged heart 1 | 210
enlarged testis 1 | 6
impaired righting response 1 | 26
increased circulating alkaline... 1 | 122
increased circulating sodium l... 1 | 71
increased erythrocyte cell num... 1 | 39
increased grip strength 1 | 41
increased hematocrit 1 | 46
increased lean body mass 1 | 172
increased leukocyte cell numbe... 1 | 47
increased monocyte cell number 1 | 63
increased vertical activity 1 | 24
preweaning lethality, incomple... 1 | 499
small testis 1 | 58
vertebral fusion 1 | 23

Disease

Carcinoma 42 | 11,493
Celiac disease 38 | 116
ovarian cancer 31 | 8,520
osteosarcoma 30 | 7,950
psoriasis 29 | 6,694
lung cancer 27 | 4,740
glioblastoma 21 | 5,792
non-small cell lung cancer 21 | 2,890
lung carcinoma 20 | 2,843
ulcerative colitis 19 | 1,819
medulloblastoma, large-cell 18 | 6,241
interstitial cystitis 17 | 2,312
Cancer 16 | 2,499
Kidney cancer 16 | 2,613
ependymoma 16 | 4,679
Astrocytoma, Pilocytic 15 | 3,081
Rheumatoid arthritis 15 | 1,191
Multiple Sclerosis 14 | 540
lung adenocarcinoma 14 | 2,716
Crohn's disease 13 | 321
adult high grade glioma 13 | 3,801
group 3 medulloblastoma 13 | 4,104
malignant mesothelioma 13 | 3,232
Breast cancer 12 | 3,578
atypical teratoid / rhabdoid tumor 12 | 5,112
intraductal papillary-mucinous carcinoma (IPMC) 12 | 2,989
invasive ductal carcinoma 12 | 2,951
Pick disease 11 | 1,894
diabetes mellitus 11 | 1,728
oligodendroglioma 11 | 2,850
subependymal giant cell astrocytoma 11 | 2,287
intraductal papillary-mucinous neoplasm (IPMN) 10 | 3,291
pituitary cancer 10 | 1,972
tuberculosis 10 | 2,010
intraductal papillary-mucinous adenoma (IPMA) 9 | 2,955
Alzheimer's disease 8 | 658
Hypersensitivity reaction type II disease 8 | 253
Melanoma 8 | 711
astrocytic glioma 8 | 2,597
primitive neuroectodermal tumor 8 | 3,035
Asthma 7 | 385
Autosomal recessive predisposition 7 | 1,442
Common variable immunodeficiency 7 | 101
Schizophrenia 7 | 1,160
Type 1 diabetes mellitus 7 | 109
cutaneous lupus erythematosus 7 | 1,057
pancreatic cancer 7 | 2,398
pancreatic ductal adenocarcinoma liver metastasis 7 | 1,962
primary Sjogren syndrome 7 | 735
Acquired metabolic disease 6 | 336
Alopecia areata 6 | 41
Arthritis, Rheumatoid 6 | 174
Skin cancer 6 | 469
adrenocortical carcinoma 6 | 1,428
autosomal dominant Emery-Dreifuss muscular dystrophy 6 | 510
breast carcinoma 6 | 1,638
juvenile dermatomyositis 6 | 1,187
non primary Sjogren syndrome sicca 6 | 891
Carcinoma, Hepatocellular 5 | 228
Kidney disease 5 | 430
Liver cancer 5 | 604
Liver carcinoma 5 | 240
Prostatic Neoplasms 5 | 495
Vitiligo 5 | 73
acute quadriplegic myopathy 5 | 1,158
astrocytoma 5 | 1,146
colon cancer 5 | 1,478
cystic fibrosis 5 | 1,696
interstitial lung disease 5 | 298
mucosa-associated lymphoid tissue lymphoma 5 | 484
Anti-nuclear factor positive 4 | 18
Arthralgia 4 | 90
Bipolar Disorder 4 | 666
Duchenne muscular dystrophy 4 | 601
Muscle hypotonia 4 | 571
Obesity 4 | 678
Polycystic ovary syndrome 4 | 360
Systemic lupus erythematosus 4 | 194
acute myeloid leukemia 4 | 783
dermatomyositis 4 | 966
gastric cancer 4 | 459
gastric carcinoma 4 | 807
medulloblastoma 4 | 720
pediatric high grade glioma 4 | 1,064
posterior fossa group A ependymoma 4 | 468
primary pancreatic ductal adenocarcinoma 4 | 1,109
progressive supranuclear palsy 4 | 676
sarcoidosis 4 | 370
Allergic hypersensitivity disease 3 | 126
Allergic rhinitis 3 | 94
Arthritis 3 | 290
Hepatomegaly 3 | 285
Hypereosinophilic syndrome 3 | 71
Prostate cancer 3 | 175
chronic lymphosyte leukemia 3 | 204
chronic rhinosinusitis 3 | 512
hepatocellular carcinoma 3 | 547
nasopharyngeal carcinoma 3 | 1,058
pancreatic carcinoma 3 | 562
spina bifida 3 | 1,074

Tissue

Digestive Tract 57 | 17,369
Endocrine System 57 | 18,159
Female tissues 57 | 17,400
Male tissues 57 | 17,142
Blood and immune system 56 | 16,909
Liver and Pancreas 56 | 16,750
Skin and soft tissues 56 | 17,230
Urinary Tract 56 | 16,678
Respiratory system 55 | 16,393
Nervous System 52 | 16,725
Cardiovascular System 51 | 15,192

Target Family

Non-IDG 33 | 12,091
Enzyme 14 | 4,145
Transcription Factor 7 | 1,400
GPCR 2 | 408
Kinase 2 | 634
Transporter 1 | 473

GWAS Trait

Celiac disease 59 | 59
Obesity-related traits 569 | 569
Schizophrenia 533 | 533
Breast cancer 492 | 492
Body mass index 379 | 379
Height 369 | 369
Coronary artery disease 367 | 367
Blood protein levels 351 | 351
Post bronchodilator FEV1-FVC r... 308 | 308
Mean corpuscular volume 283 | 283
Platelet count 275 | 275
Intelligence (multi-trait anal... 267 | 267
Mean platelet volume 253 | 253
IgG glycosylation 250 | 250
Mean corpuscular hemoglobin 238 | 238
Inflammatory bowel disease 235 | 235
Plateletcrit 227 | 227
Crohn's disease 215 | 215
Type 2 diabetes 210 | 210
Red blood cell count 191 | 191
Monocyte count 183 | 183
Red cell distribution width 182 | 182
Eosinophil counts 180 | 180
Neuroticism 180 | 180
Platelet distribution width 174 | 174
Monocyte percentage of white c... 173 | 173
Post bronchodilator FEV1 173 | 173
Sum eosinophil basophil counts 173 | 173
White blood cell count 172 | 172
3-hydroxy-1-methylpropylmercap... 166 | 166
Eosinophil percentage of granu... 163 | 163
Eosinophil percentage of white... 163 | 163
Reticulocyte fraction of red c... 163 | 163
Ulcerative colitis 163 | 163
Granulocyte percentage of myel... 162 | 162
Itch intensity from mosquito b... 162 | 162
Systemic lupus erythematosus 159 | 159
High light scatter reticulocyt... 158 | 158
Lymphocyte counts 158 | 158
Reticulocyte count 158 | 158
Blood metabolite levels 157 | 157
Neutrophil count 154 | 154
High light scatter reticulocyt... 153 | 153
Neutrophil percentage of granu... 153 | 153
3-hydroxypropylmercapturic aci... 150 | 150
Tonsillectomy 149 | 149
Diastolic blood pressure 144 | 144
Sum basophil neutrophil counts 140 | 140
Autism spectrum disorder or sc... 134 | 134
Myeloid white cell count 133 | 133
Granulocyte count 132 | 132
Sum neutrophil eosinophil coun... 129 | 129
Colorectal cancer 126 | 126
Alzheimer disease and age of o... 124 | 124
Multiple sclerosis 124 | 124
Cholesterol, total 123 | 123
Night sleep phenotypes 123 | 123
Lung cancer 122 | 122
Lymphocyte percentage of white... 122 | 122
Menarche (age at onset) 122 | 122
Neutrophil percentage of white... 121 | 121
Rheumatoid arthritis 121 | 121
Systolic blood pressure 120 | 120
Immature fraction of reticuloc... 118 | 118
Diisocyanate-induced asthma 116 | 116
HDL cholesterol 116 | 116
Allergic disease (asthma, hay ... 115 | 115
Educational attainment (years ... 114 | 114
Hematocrit 113 | 113
Hemoglobin concentration 112 | 112
LDL cholesterol 110 | 110
QT interval 110 | 110
Waist circumference adjusted f... 110 | 110
Mosquito bite size 107 | 107
Asthma 106 | 106
Lobe attachment (rater-scored ... 103 | 103
Peripheral arterial disease (t... 101 | 101
Pulse pressure 97 | 97
Bipolar disorder 94 | 94
Major depressive disorder 94 | 94
Prostate cancer 92 | 92
Parkinson's disease 90 | 90
Hip circumference adjusted for... 89 | 89
Metabolite levels 87 | 87
Triglycerides 87 | 87
Colonoscopy-negative controls ... 85 | 85
Mean corpuscular hemoglobin co... 85 | 85
Itch intensity from mosquito b... 84 | 84
Bipolar disorder and schizophr... 83 | 83
Resting heart rate 82 | 82
Macrophage inflammatory protei... 81 | 81
Migraine 81 | 81
Waist-to-hip ratio adjusted fo... 81 | 81
PR interval in Tripanosoma cru... 80 | 80
Cognitive performance 79 | 79
Glomerular filtration rate (cr... 78 | 78
Late-onset Alzheimer's disease 78 | 78
Waist circumference adjusted f... 75 | 75
Tuberculosis 73 | 73
Type 1 diabetes 73 | 73
Morning vs. evening chronotype 72 | 72

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Serine/threonine-protein kinase 32B STK32B Tchem Kinase -0.54101 2.56 98
Ankyrin repeat and fibronectin type-III domain-containing protein 1 ANKFN1 Tdark Non-IDG 0.06 0.71 13
FERM domain-containing protein 4B FRMD4B Tdark Non-IDG -0.63178 4.93 32
Lipoma-preferred partner LPP Tbio Non-IDG -2.77949 582.6 164
Nuclear factor 1 A-type NFIA Tbio Transcription Factor -1.80602 47.4 163
Transcription regulator protein BACH2 BACH2 Tbio Transcription Factor -1.90906 89.8 184
Zinc finger MIZ domain-containing protein 1 ZMIZ1 Tbio Transcription Factor -1.57174 37.9 126
Membrane metallo-endopeptidase-like 1 MMEL1 Tchem Enzyme -1.49216 32.7 122
Interleukin-1 receptor-like 1 IL1RL1 Tbio Non-IDG -2.06895 107.0 347
ERBB receptor feedback inhibitor 1 ERRFI1 Tbio Non-IDG -1.86682 77.3 148