Development Level

Tbio 24 | 11,445
Tchem 7 | 1,598
Tdark 6 | 6,588
Tclin 2 | 613

Collection

Kinase: IDG Consortium (Target... 2 | 125

IMPC Phenotype

decreased grip strength 2 | 116
increased circulating creatini... 2 | 38
preweaning lethality, complete... 2 | 979
abnormal bone structure 1 | 187
abnormal gait 1 | 69
decreased bone mineral density 1 | 126
decreased hematocrit 1 | 46
decreased lean body mass 1 | 135
decreased mean corpuscular vol... 1 | 79
hypoactivity 1 | 132
increased basophil cell number 1 | 7
increased blood urea nitrogen ... 1 | 48
increased circulating HDL chol... 1 | 80
increased circulating alkaline... 1 | 122
increased circulating phosphat... 1 | 26
increased circulating serum al... 1 | 22
increased circulating total pr... 1 | 28
increased eosinophil cell numb... 1 | 11
increased grip strength 1 | 41
increased mean corpuscular hem... 1 | 36
increased mean platelet volume 1 | 45
increased or absent threshold ... 1 | 101
increased total body fat amoun... 1 | 134
preweaning lethality, incomple... 1 | 499

Disease

Carcinoma 33 | 11,493
osteosarcoma 21 | 7,950
medulloblastoma, large-cell 18 | 6,241
ovarian cancer 16 | 8,520
psoriasis 15 | 6,694
lung cancer 14 | 4,740
glioblastoma 13 | 5,792
Kidney cancer 11 | 2,613
atypical teratoid / rhabdoid tumor 11 | 5,112
primitive neuroectodermal tumor 10 | 3,035
ependymoma 9 | 4,679
Astrocytoma, Pilocytic 8 | 3,081
Breast cancer 8 | 3,578
Rheumatoid arthritis 8 | 1,191
group 3 medulloblastoma 8 | 4,104
oligodendroglioma 8 | 2,850
pancreatic ductal adenocarcinoma liver metastasis 8 | 1,962
Cancer 7 | 2,499
adult high grade glioma 7 | 3,801
astrocytic glioma 7 | 2,597
intraductal papillary-mucinous carcinoma (IPMC) 7 | 2,989
intraductal papillary-mucinous neoplasm (IPMN) 7 | 3,291
lung adenocarcinoma 7 | 2,716
non-small cell lung cancer 7 | 2,890
pituitary cancer 7 | 1,972
Schizophrenia 6 | 1,160
colon cancer 6 | 1,478
group 4 medulloblastoma 6 | 1,855
invasive ductal carcinoma 6 | 2,951
malignant mesothelioma 6 | 3,232
pancreatic cancer 6 | 2,398
Autosomal recessive predisposition 5 | 1,442
Pick disease 5 | 1,894
breast carcinoma 5 | 1,638
intraductal papillary-mucinous adenoma (IPMA) 5 | 2,955
spina bifida 5 | 1,074
Bipolar Disorder 4 | 666
acute quadriplegic myopathy 4 | 1,158
cystic fibrosis 4 | 1,696
juvenile dermatomyositis 4 | 1,187
pancreatic carcinoma 4 | 562
posterior fossa group B ependymoma 4 | 416
subependymal giant cell astrocytoma 4 | 2,287
Attention deficit hyperactivity disorder 3 | 278
Cardiovascular system disease 3 | 246
Chronic obstructive pulmonary disease 3 | 184
Diarrhea 3 | 253
Hepatomegaly 3 | 285
Icterus 3 | 82
Intellectual disability 3 | 1,016
Liver neoplasms 3 | 130
Mental Depression 3 | 333
Mood disorder 3 | 14
Multiple myeloma 3 | 1,332
active Crohn's disease 3 | 922
acute myeloid leukemia 3 | 783
aldosterone-producing adenoma 3 | 665
astrocytoma 3 | 1,146
cutaneous lupus erythematosus 3 | 1,057
dermatomyositis 3 | 966
esophageal adenocarcinoma 3 | 737
lung carcinoma 3 | 2,843
non primary Sjogren syndrome sicca 3 | 891
pediatric high grade glioma 3 | 1,064
substance-related disorder 3 | 162
tuberculosis and treatment for 6 months 3 | 409
ulcerative colitis 3 | 1,819
Adult onset 2 | 82
Autistic Disorder 2 | 364
Bladder Neoplasm 2 | 112
Cholestasis 2 | 155
Colonic Neoplasms 2 | 142
Coronary artery disease 2 | 268
Depressive disorder 2 | 409
Endometrial cancer 2 | 311
Essential Hypertension 2 | 94
Hypercholesterolemia 2 | 44
Hypoglycemia 2 | 152
Kidney disease 2 | 430
Liver Cirrhosis 2 | 181
Liver Cirrhosis, Experimental 2 | 769
Liver Dysfunction 2 | 99
Lung Neoplasms 2 | 232
Melanoma 2 | 711
Multiple Sclerosis 2 | 540
Orofacial cleft 2 | 54
Osteoporosis 2 | 363
Prostatic Neoplasms 2 | 495
Skin cancer 2 | 469
Stomach Neoplasms 2 | 300
Urinary Bladder Neoplasms 2 | 114
Waldenstrons macroglobulinemia 2 | 765
active ulcerative colitis 2 | 764
chronic rhinosinusitis 2 | 512
diabetes mellitus 2 | 1,728
ductal carcinoma in situ 2 | 1,745
interstitial cystitis 2 | 2,312
medulloblastoma 2 | 720
mucosa-associated lymphoid tissue lymphoma 2 | 484
nephrosclerosis 2 | 333

Tissue

Endocrine System 37 | 18,159
Liver and Pancreas 37 | 16,750
Male tissues 37 | 17,142
Digestive Tract 36 | 17,369
Female tissues 36 | 17,400
Urinary Tract 36 | 16,678
Blood and immune system 35 | 16,909
Nervous System 35 | 16,725
Skin and soft tissues 35 | 17,230
Respiratory system 32 | 16,393
Cardiovascular System 31 | 15,192

Target Family

Non-IDG 17 | 12,091
Enzyme 8 | 4,145
Transporter 6 | 473
Kinase 3 | 634
Epigenetic 2 | 242
Nuclear Receptor 2 | 48
TF/Epigenetic 1 | 38

GWAS Trait

CTACK levels 39 | 39
Obesity-related traits 569 | 569
Schizophrenia 533 | 533
Breast cancer 492 | 492
Body mass index 379 | 379
Height 369 | 369
Coronary artery disease 367 | 367
Blood protein levels 351 | 351
Post bronchodilator FEV1-FVC r... 308 | 308
Mean corpuscular volume 283 | 283
Platelet count 275 | 275
Intelligence (multi-trait anal... 267 | 267
Mean platelet volume 253 | 253
IgG glycosylation 250 | 250
Mean corpuscular hemoglobin 238 | 238
Inflammatory bowel disease 235 | 235
Plateletcrit 227 | 227
Crohn's disease 215 | 215
Type 2 diabetes 210 | 210
Red blood cell count 191 | 191
Monocyte count 183 | 183
Red cell distribution width 182 | 182
Eosinophil counts 180 | 180
Neuroticism 180 | 180
Platelet distribution width 174 | 174
Monocyte percentage of white c... 173 | 173
Post bronchodilator FEV1 173 | 173
Sum eosinophil basophil counts 173 | 173
White blood cell count 172 | 172
3-hydroxy-1-methylpropylmercap... 166 | 166
Eosinophil percentage of granu... 163 | 163
Eosinophil percentage of white... 163 | 163
Reticulocyte fraction of red c... 163 | 163
Ulcerative colitis 163 | 163
Granulocyte percentage of myel... 162 | 162
Itch intensity from mosquito b... 162 | 162
Systemic lupus erythematosus 159 | 159
High light scatter reticulocyt... 158 | 158
Lymphocyte counts 158 | 158
Reticulocyte count 158 | 158
Blood metabolite levels 157 | 157
Neutrophil count 154 | 154
High light scatter reticulocyt... 153 | 153
Neutrophil percentage of granu... 153 | 153
3-hydroxypropylmercapturic aci... 150 | 150
Tonsillectomy 149 | 149
Diastolic blood pressure 144 | 144
Sum basophil neutrophil counts 140 | 140
Autism spectrum disorder or sc... 134 | 134
Myeloid white cell count 133 | 133
Granulocyte count 132 | 132
Sum neutrophil eosinophil coun... 129 | 129
Colorectal cancer 126 | 126
Alzheimer disease and age of o... 124 | 124
Multiple sclerosis 124 | 124
Cholesterol, total 123 | 123
Night sleep phenotypes 123 | 123
Lung cancer 122 | 122
Lymphocyte percentage of white... 122 | 122
Menarche (age at onset) 122 | 122
Neutrophil percentage of white... 121 | 121
Rheumatoid arthritis 121 | 121
Systolic blood pressure 120 | 120
Immature fraction of reticuloc... 118 | 118
Diisocyanate-induced asthma 116 | 116
HDL cholesterol 116 | 116
Allergic disease (asthma, hay ... 115 | 115
Educational attainment (years ... 114 | 114
Hematocrit 113 | 113
Hemoglobin concentration 112 | 112
LDL cholesterol 110 | 110
QT interval 110 | 110
Waist circumference adjusted f... 110 | 110
Mosquito bite size 107 | 107
Asthma 106 | 106
Lobe attachment (rater-scored ... 103 | 103
Peripheral arterial disease (t... 101 | 101
Pulse pressure 97 | 97
Bipolar disorder 94 | 94
Major depressive disorder 94 | 94
Prostate cancer 92 | 92
Parkinson's disease 90 | 90
Hip circumference adjusted for... 89 | 89
Metabolite levels 87 | 87
Triglycerides 87 | 87
Colonoscopy-negative controls ... 85 | 85
Mean corpuscular hemoglobin co... 85 | 85
Itch intensity from mosquito b... 84 | 84
Bipolar disorder and schizophr... 83 | 83
Resting heart rate 82 | 82
Macrophage inflammatory protei... 81 | 81
Migraine 81 | 81
Waist-to-hip ratio adjusted fo... 81 | 81
PR interval in Tripanosoma cru... 80 | 80
Cognitive performance 79 | 79
Glomerular filtration rate (cr... 78 | 78
Late-onset Alzheimer's disease 78 | 78
Waist circumference adjusted f... 75 | 75
Tuberculosis 73 | 73
Type 1 diabetes 73 | 73
Morning vs. evening chronotype 72 | 72

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Integrin alpha-11 ITGA11 Tbio Non-IDG -1.13736 14.3 76
Sodium bicarbonate cotransporter 3 SLC4A7 Tbio Transporter -1.82039 64.7 133
Protein polybromo-1 PBRM1 Tchem TF/Epigenetic -1.92500 84.6 97
Leucine-rich repeat-containing protein 7 LRRC7 Tbio Non-IDG -1.45630 31.2 41
Coagulation factor V F5 Tbio Non-IDG -2.73955 525.3 198
Iron-responsive element-binding protein 2 IREB2 Tbio Non-IDG -2.33609 211.7 253
Probable phospholipid-transporting ATPase VB ATP10B Tdark Transporter 0.48 0.35 10
Solute carrier organic anion transporter family member 1C1 SLCO1C1 Tbio Transporter -1.75242 51.4 66
Tyrosine-protein phosphatase non-receptor type 3 PTPN3 Tbio Enzyme -1.40961 29.1 162
Serine/threonine-protein kinase Nek10 NEK10 Tdark Kinase -0.45108 2.23 50