Development Level

Tbio 12 | 11,445
Tchem 4 | 1,598

IMPC Phenotype

decreased circulating HDL chol... 2 | 68
decreased circulating choleste... 2 | 93
abnormal bone structure 1 | 187
abnormal retinal blood vessel ... 1 | 26
abnormal retinal vasculature m... 1 | 27
abnormal seminal vesicle morph... 1 | 114
abnormal spine curvature 1 | 9
abnormal testis morphology 1 | 43
decreased body weight 1 | 161
decreased circulating LDL chol... 1 | 38
decreased circulating alanine ... 1 | 47
decreased circulating aspartat... 1 | 34
decreased circulating free fat... 1 | 31
decreased circulating glucose ... 1 | 126
decreased circulating iron lev... 1 | 32
decreased lactate dehydrogenas... 1 | 16
decreased prepulse inhibition 1 | 82
hyperactivity 1 | 148
hypoactivity 1 | 132
improved glucose tolerance 1 | 79
increased heart rate 1 | 23
increased heart weight 1 | 62
increased total retina thickne... 1 | 4
mydriasis 1 | 6
preweaning lethality, incomple... 1 | 499
small testis 1 | 58
vertebral transformation 1 | 12

Disease

Carcinoma 11 | 11,493
diabetes mellitus 10 | 1,728
ovarian cancer 10 | 8,520
medulloblastoma, large-cell 9 | 6,241
glioblastoma 8 | 5,792
Lipid metabolism disorder 7 | 114
Type 2 diabetes mellitus 7 | 272
pancreatic ductal adenocarcinoma liver metastasis 7 | 1,962
Atherosclerosis 6 | 291
Breast cancer 6 | 3,578
Coronary artery disease 6 | 268
intraductal papillary-mucinous neoplasm (IPMN) 6 | 3,291
lung cancer 6 | 4,740
oligodendroglioma 6 | 2,850
psoriasis 6 | 6,694
Cardiovascular system disease 5 | 246
Kidney cancer 5 | 2,613
Obesity 5 | 678
adrenocortical carcinoma 5 | 1,428
atypical teratoid / rhabdoid tumor 5 | 5,112
ductal carcinoma in situ 5 | 1,745
intraductal papillary-mucinous carcinoma (IPMC) 5 | 2,989
malignant mesothelioma 5 | 3,232
Acquired metabolic disease 4 | 336
Metabolic syndrome X 4 | 52
Vascular disease 4 | 319
ependymoma 4 | 4,679
group 3 medulloblastoma 4 | 4,104
interstitial cystitis 4 | 2,312
intraductal papillary-mucinous adenoma (IPMA) 4 | 2,955
invasive ductal carcinoma 4 | 2,951
non-small cell lung cancer 4 | 2,890
osteosarcoma 4 | 7,950
Diabetes Mellitus, Non-Insulin-Dependent 3 | 145
Diabetes Mellitus, Type 2 3 | 142
Intellectual disability 3 | 1,016
Macular degeneration 3 | 65
adult high grade glioma 3 | 3,801
aldosterone-producing adenoma 3 | 665
astrocytic glioma 3 | 2,597
astrocytoma 3 | 1,146
breast carcinoma 3 | 1,638
group 4 medulloblastoma 3 | 1,855
lung carcinoma 3 | 2,843
pediatric high grade glioma 3 | 1,064
primitive neuroectodermal tumor 3 | 3,035
tuberculosis 3 | 2,010
Age related macular degeneration 2 | 72
Atopic dermatitis 2 | 952
Autistic Disorder 2 | 364
Cholesteryl Ester Transfer Protein Deficiency 2 | 3
Depressive disorder 2 | 409
Diabetes Mellitus, Noninsulin-Dependent 2 | 31
Disease Models, Animal 2 | 155
Duchenne muscular dystrophy 2 | 601
Dull intelligence 2 | 645
Dyslipidemias 2 | 27
Hypercholesterolemia, Familial 2 | 23
Hyperlipidemia 2 | 43
Hyperlipidemias 2 | 17
Hyperlipoproteinemia Type II 2 | 12
Hyperlipoproteinemias 2 | 5
Hypertriglyceridemia 2 | 17
Insulin Resistance 2 | 72
Liver cancer 2 | 604
Low intelligence 2 | 645
Mental Retardation 2 | 645
Mental deficiency 2 | 645
Pediatric Obesity 2 | 4
Pick disease 2 | 1,894
Poor school performance 2 | 645
Proteinuria 2 | 144
Rheumatoid arthritis 2 | 1,191
Short stature 2 | 531
Tremor 2 | 113
acute myeloid leukemia 2 | 783
acute quadriplegic myopathy 2 | 1,158
colon cancer 2 | 1,478
esophageal adenocarcinoma 2 | 737
juvenile dermatomyositis 2 | 1,187
subependymal giant cell astrocytoma 2 | 2,287
Acquired flat foot 1 | 72
Cerebellar Dysmetria 1 | 56
Cerebral Ischemia 1 | 37
Elfin facies 1 | 10
Hyperkyphosis 1 | 111
Hypoplastic toenails 1 | 22
Microdontia (disorder) 1 | 59
Narrow face 1 | 54
Obsessive compulsive behavior 1 | 25
Open Bite 1 | 21
Pelvic kidney 1 | 10
Periorbital edema 1 | 13
Periorbital swelling 1 | 13
Peripheral pulmonary artery stenosis 1 | 14
Phonophobia 1 | 11
Prominent lower lip 1 | 64
Sleeplessness 1 | 16
Thin face 1 | 54
Williams Syndrome 1 | 10

Tissue

Blood and immune system 16 | 16,909
Cardiovascular System 16 | 15,192
Digestive Tract 16 | 17,369
Endocrine System 16 | 18,159
Female tissues 16 | 17,400
Liver and Pancreas 16 | 16,750
Male tissues 16 | 17,142
Respiratory system 16 | 16,393
Skin and soft tissues 16 | 17,230
Urinary Tract 16 | 16,678
Nervous System 15 | 16,725

Target Family

Non-IDG 8 | 12,091
Enzyme 4 | 4,145
Epigenetic 2 | 242
GPCR 1 | 408
Nuclear Receptor 1 | 48

GWAS Trait

C-reactive protein levels or H... 16 | 16
Obesity-related traits 569 | 569
Schizophrenia 533 | 533
Breast cancer 492 | 492
Body mass index 379 | 379
Height 369 | 369
Coronary artery disease 367 | 367
Blood protein levels 351 | 351
Post bronchodilator FEV1-FVC r... 308 | 308
Mean corpuscular volume 283 | 283
Platelet count 275 | 275
Intelligence (multi-trait anal... 267 | 267
Mean platelet volume 253 | 253
IgG glycosylation 250 | 250
Mean corpuscular hemoglobin 238 | 238
Inflammatory bowel disease 235 | 235
Plateletcrit 227 | 227
Crohn's disease 215 | 215
Type 2 diabetes 210 | 210
Red blood cell count 191 | 191
Monocyte count 183 | 183
Red cell distribution width 182 | 182
Eosinophil counts 180 | 180
Neuroticism 180 | 180
Platelet distribution width 174 | 174
Monocyte percentage of white c... 173 | 173
Post bronchodilator FEV1 173 | 173
Sum eosinophil basophil counts 173 | 173
White blood cell count 172 | 172
3-hydroxy-1-methylpropylmercap... 166 | 166
Eosinophil percentage of granu... 163 | 163
Eosinophil percentage of white... 163 | 163
Reticulocyte fraction of red c... 163 | 163
Ulcerative colitis 163 | 163
Granulocyte percentage of myel... 162 | 162
Itch intensity from mosquito b... 162 | 162
Systemic lupus erythematosus 159 | 159
High light scatter reticulocyt... 158 | 158
Lymphocyte counts 158 | 158
Reticulocyte count 158 | 158
Blood metabolite levels 157 | 157
Neutrophil count 154 | 154
High light scatter reticulocyt... 153 | 153
Neutrophil percentage of granu... 153 | 153
3-hydroxypropylmercapturic aci... 150 | 150
Tonsillectomy 149 | 149
Diastolic blood pressure 144 | 144
Sum basophil neutrophil counts 140 | 140
Autism spectrum disorder or sc... 134 | 134
Myeloid white cell count 133 | 133
Granulocyte count 132 | 132
Sum neutrophil eosinophil coun... 129 | 129
Colorectal cancer 126 | 126
Alzheimer disease and age of o... 124 | 124
Multiple sclerosis 124 | 124
Cholesterol, total 123 | 123
Night sleep phenotypes 123 | 123
Lung cancer 122 | 122
Lymphocyte percentage of white... 122 | 122
Menarche (age at onset) 122 | 122
Neutrophil percentage of white... 121 | 121
Rheumatoid arthritis 121 | 121
Systolic blood pressure 120 | 120
Immature fraction of reticuloc... 118 | 118
Diisocyanate-induced asthma 116 | 116
HDL cholesterol 116 | 116
Allergic disease (asthma, hay ... 115 | 115
Educational attainment (years ... 114 | 114
Hematocrit 113 | 113
Hemoglobin concentration 112 | 112
LDL cholesterol 110 | 110
QT interval 110 | 110
Waist circumference adjusted f... 110 | 110
Mosquito bite size 107 | 107
Asthma 106 | 106
Lobe attachment (rater-scored ... 103 | 103
Peripheral arterial disease (t... 101 | 101
Pulse pressure 97 | 97
Bipolar disorder 94 | 94
Major depressive disorder 94 | 94
Prostate cancer 92 | 92
Parkinson's disease 90 | 90
Hip circumference adjusted for... 89 | 89
Metabolite levels 87 | 87
Triglycerides 87 | 87
Colonoscopy-negative controls ... 85 | 85
Mean corpuscular hemoglobin co... 85 | 85
Itch intensity from mosquito b... 84 | 84
Bipolar disorder and schizophr... 83 | 83
Resting heart rate 82 | 82
Macrophage inflammatory protei... 81 | 81
Migraine 81 | 81
Waist-to-hip ratio adjusted fo... 81 | 81
PR interval in Tripanosoma cru... 80 | 80
Cognitive performance 79 | 79
Glomerular filtration rate (cr... 78 | 78
Late-onset Alzheimer's disease 78 | 78
Waist circumference adjusted f... 75 | 75
Tuberculosis 73 | 73
Type 1 diabetes 73 | 73
Morning vs. evening chronotype 72 | 72

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Tyrosine-protein kinase BAZ1B BAZ1B Tbio Epigenetic -1.45627 32.0 155
Cohesin subunit SA-1 STAG1 Tbio Non-IDG -2.47449 292.2 200
Cadherin EGF LAG seven-pass G-type receptor 2 CELSR2 Tbio GPCR -1.22995 16.7 139
Beta-1-syntrophin SNTB1 Tbio Non-IDG -1.06492 9.50 111
Apolipoprotein C-I APOC1 Tbio Non-IDG -2.39715 256.4 274
Keratinocyte differentiation factor 1 KDF1 Tbio Non-IDG -0.26977 2.27 78
Group XV phospholipase A2 PLA2G15 Tbio Enzyme -1.68759 48.7 88
Cholesteryl ester transfer protein CETP Tchem Non-IDG -3.20658 1755.9 264
Alpha-ketoglutarate-dependent dioxygenase FTO FTO Tbio Enzyme -3.13021 1342.0 318
Polyadenylate-binding protein 4 PABPC4 Tbio Non-IDG -0.92422 8.32 150