Development Level

Tbio 9 | 11,445
Tchem 6 | 1,598
Tclin 4 | 613
Tdark 1 | 6,588

IMPC Phenotype

increased hemoglobin content 3 | 45
abnormal behavior 1 | 298
abnormal bone structure 1 | 187
abnormal gait 1 | 69
abnormal heart morphology 1 | 162
abnormal locomotor behavior 1 | 24
abnormal retinal blood vessel ... 1 | 26
abnormal retinal vasculature m... 1 | 27
abnormal spine curvature 1 | 9
decreased bone mineral content 1 | 151
decreased bone mineral density 1 | 126
decreased circulating HDL chol... 1 | 68
decreased circulating chloride... 1 | 30
decreased circulating choleste... 1 | 93
decreased circulating free fat... 1 | 31
decreased circulating glucose ... 1 | 126
decreased heart weight 1 | 27
decreased lean body mass 1 | 135
decreased leukocyte cell numbe... 1 | 73
decreased lymphocyte cell numb... 1 | 83
decreased prepulse inhibition 1 | 82
decreased spleen weight 1 | 10
decreased vertical activity 1 | 208
enlarged heart 1 | 210
enlarged liver 1 | 2
hypoactivity 1 | 132
impaired righting response 1 | 26
increased circulating HDL chol... 1 | 80
increased circulating alanine ... 1 | 13
increased circulating alkaline... 1 | 122
increased circulating aspartat... 1 | 15
increased circulating bilirubi... 1 | 16
increased circulating calcium ... 1 | 34
increased circulating choleste... 1 | 66
increased circulating fructosa... 1 | 13
increased circulating glucose ... 1 | 24
increased circulating iron lev... 1 | 30
increased circulating phosphat... 1 | 26
increased circulating potassiu... 1 | 29
increased circulating serum al... 1 | 22
increased circulating total pr... 1 | 28
increased heart weight 1 | 62
increased hematocrit 1 | 46
increased mean corpuscular hem... 1 | 96
increased mean corpuscular vol... 1 | 92
increased mean platelet volume 1 | 45
increased monocyte cell number 1 | 63
increased neutrophil cell numb... 1 | 46
increased or absent threshold ... 1 | 101
increased total body fat amoun... 1 | 134
increased total retina thickne... 1 | 4
limb grasping 1 | 41
small seminal vesicle 1 | 10
thrombocytopenia 1 | 56
tremors 1 | 39
trunk curl 1 | 16

Disease

Carcinoma 13 | 11,493
diabetes mellitus 10 | 1,728
Cancer 9 | 2,499
non-small cell lung cancer 8 | 2,890
osteosarcoma 8 | 7,950
glioblastoma 7 | 5,792
lung cancer 7 | 4,740
ulcerative colitis 7 | 1,819
Cardiovascular system disease 6 | 246
cystic fibrosis 6 | 1,696
intraductal papillary-mucinous neoplasm (IPMN) 6 | 3,291
invasive ductal carcinoma 6 | 2,951
medulloblastoma, large-cell 6 | 6,241
ovarian cancer 6 | 8,520
psoriasis 6 | 6,694
Atherosclerosis 5 | 291
Lipid metabolism disorder 5 | 114
Obesity 5 | 678
ependymoma 5 | 4,679
intraductal papillary-mucinous adenoma (IPMA) 5 | 2,955
malignant mesothelioma 5 | 3,232
pancreatic ductal adenocarcinoma liver metastasis 5 | 1,962
Arthritis 4 | 290
Asthma 4 | 385
Astrocytoma, Pilocytic 4 | 3,081
Bipolar Disorder 4 | 666
Breast cancer 4 | 3,578
Crohn's disease 4 | 321
Diabetes Mellitus, Non-Insulin-Dependent 4 | 145
Diabetes Mellitus, Type 2 4 | 142
Hepatomegaly 4 | 285
Rheumatoid arthritis 4 | 1,191
Type 2 diabetes mellitus 4 | 272
adult high grade glioma 4 | 3,801
atypical teratoid / rhabdoid tumor 4 | 5,112
cutaneous lupus erythematosus 4 | 1,057
intraductal papillary-mucinous carcinoma (IPMC) 4 | 2,989
lung adenocarcinoma 4 | 2,716
pituitary cancer 4 | 1,972
tuberculosis 4 | 2,010
Acquired metabolic disease 3 | 336
Alzheimer's disease 3 | 658
Arthritis, Rheumatoid 3 | 174
Arthropathy 3 | 43
Atopic dermatitis 3 | 952
Crohn Disease 3 | 45
Diarrhea 3 | 253
Fatty liver disease 3 | 103
Gout 3 | 106
Hyperglycemia 3 | 137
Hyperinsulinism 3 | 133
Hypersensitivity reaction type II disease 3 | 253
Kidney cancer 3 | 2,613
Kidney disease 3 | 430
Leishmaniasis 3 | 47
Osteoporosis 3 | 363
Pallor 3 | 40
Pick disease 3 | 1,894
Schizophrenia 3 | 1,160
Stomach Neoplasms 3 | 300
Tremor 3 | 113
Vascular disease 3 | 319
breast carcinoma 3 | 1,638
colon cancer 3 | 1,478
esophageal adenocarcinoma 3 | 737
group 4 medulloblastoma 3 | 1,855
lung carcinoma 3 | 2,843
maturity-onset diabetes of the young 3 | 32
pancreatic cancer 3 | 2,398
periodontitis 3 | 293
primary Sjogren syndrome 3 | 735
primitive neuroectodermal tumor 3 | 3,035
subependymal giant cell astrocytoma 3 | 2,287
Adenoma 2 | 167
Anemia 2 | 365
Chronic obstructive pulmonary disease 2 | 184
Coronary artery disease 2 | 268
Dermatitis 2 | 157
Elevated hepatic transaminases 2 | 81
Epilepsy 2 | 792
Hepatic enzyme increased 2 | 81
Hypertension 2 | 396
Hypoglycemia 2 | 152
Inflammatory bowel disease 2 | 151
Liver Dysfunction 2 | 99
Liver enzymes abnormal 2 | 81
Liver function test increased 2 | 81
Liver function tests abnormal finding 2 | 81
Lung Neoplasms 2 | 232
Lung disease 2 | 142
Malaria 2 | 160
Osteomyelitis 2 | 42
Peripheral vascular disease 2 | 87
Peritonitis 2 | 43
Seizures 2 | 596
Subclinical abnormal liver function tests 2 | 81
Transaminases increased 2 | 81
Urticaria 2 | 67
Vasculitis 2 | 80
Vomiting 2 | 116

Tissue

Digestive Tract 19 | 17,369
Endocrine System 19 | 18,159
Female tissues 19 | 17,400
Urinary Tract 19 | 16,678
Blood and immune system 18 | 16,909
Skin and soft tissues 18 | 17,230
Liver and Pancreas 17 | 16,750
Male tissues 17 | 17,142
Nervous System 16 | 16,725
Respiratory system 15 | 16,393
Cardiovascular System 14 | 15,192

Target Family

Non-IDG 12 | 12,091
Transcription Factor 3 | 1,400
Enzyme 2 | 4,145
Nuclear Receptor 2 | 48
GPCR 1 | 408

GWAS Trait

C-reactive protein levels 20 | 20
Obesity-related traits 569 | 569
Schizophrenia 533 | 533
Breast cancer 492 | 492
Body mass index 379 | 379
Height 369 | 369
Coronary artery disease 367 | 367
Blood protein levels 351 | 351
Post bronchodilator FEV1-FVC r... 308 | 308
Mean corpuscular volume 283 | 283
Platelet count 275 | 275
Intelligence (multi-trait anal... 267 | 267
Mean platelet volume 253 | 253
IgG glycosylation 250 | 250
Mean corpuscular hemoglobin 238 | 238
Inflammatory bowel disease 235 | 235
Plateletcrit 227 | 227
Crohn's disease 215 | 215
Type 2 diabetes 210 | 210
Red blood cell count 191 | 191
Monocyte count 183 | 183
Red cell distribution width 182 | 182
Eosinophil counts 180 | 180
Neuroticism 180 | 180
Platelet distribution width 174 | 174
Monocyte percentage of white c... 173 | 173
Post bronchodilator FEV1 173 | 173
Sum eosinophil basophil counts 173 | 173
White blood cell count 172 | 172
3-hydroxy-1-methylpropylmercap... 166 | 166
Eosinophil percentage of granu... 163 | 163
Eosinophil percentage of white... 163 | 163
Reticulocyte fraction of red c... 163 | 163
Ulcerative colitis 163 | 163
Granulocyte percentage of myel... 162 | 162
Itch intensity from mosquito b... 162 | 162
Systemic lupus erythematosus 159 | 159
High light scatter reticulocyt... 158 | 158
Lymphocyte counts 158 | 158
Reticulocyte count 158 | 158
Blood metabolite levels 157 | 157
Neutrophil count 154 | 154
High light scatter reticulocyt... 153 | 153
Neutrophil percentage of granu... 153 | 153
3-hydroxypropylmercapturic aci... 150 | 150
Tonsillectomy 149 | 149
Diastolic blood pressure 144 | 144
Sum basophil neutrophil counts 140 | 140
Autism spectrum disorder or sc... 134 | 134
Myeloid white cell count 133 | 133
Granulocyte count 132 | 132
Sum neutrophil eosinophil coun... 129 | 129
Colorectal cancer 126 | 126
Alzheimer disease and age of o... 124 | 124
Multiple sclerosis 124 | 124
Cholesterol, total 123 | 123
Night sleep phenotypes 123 | 123
Lung cancer 122 | 122
Lymphocyte percentage of white... 122 | 122
Menarche (age at onset) 122 | 122
Neutrophil percentage of white... 121 | 121
Rheumatoid arthritis 121 | 121
Systolic blood pressure 120 | 120
Immature fraction of reticuloc... 118 | 118
Diisocyanate-induced asthma 116 | 116
HDL cholesterol 116 | 116
Allergic disease (asthma, hay ... 115 | 115
Educational attainment (years ... 114 | 114
Hematocrit 113 | 113
Hemoglobin concentration 112 | 112
LDL cholesterol 110 | 110
QT interval 110 | 110
Waist circumference adjusted f... 110 | 110
Mosquito bite size 107 | 107
Asthma 106 | 106
Lobe attachment (rater-scored ... 103 | 103
Peripheral arterial disease (t... 101 | 101
Pulse pressure 97 | 97
Bipolar disorder 94 | 94
Major depressive disorder 94 | 94
Prostate cancer 92 | 92
Parkinson's disease 90 | 90
Hip circumference adjusted for... 89 | 89
Metabolite levels 87 | 87
Triglycerides 87 | 87
Colonoscopy-negative controls ... 85 | 85
Mean corpuscular hemoglobin co... 85 | 85
Itch intensity from mosquito b... 84 | 84
Bipolar disorder and schizophr... 83 | 83
Resting heart rate 82 | 82
Macrophage inflammatory protei... 81 | 81
Migraine 81 | 81
Waist-to-hip ratio adjusted fo... 81 | 81
PR interval in Tripanosoma cru... 80 | 80
Cognitive performance 79 | 79
Glomerular filtration rate (cr... 78 | 78
Late-onset Alzheimer's disease 78 | 78
Waist circumference adjusted f... 75 | 75
Tuberculosis 73 | 73
Type 1 diabetes 73 | 73
Morning vs. evening chronotype 72 | 72

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
NACHT, LRR and PYD domains-containing protein 3 NLRP3 Tchem Non-IDG -3.29685 1936.6 519
Apolipoprotein C-I APOC1 Tbio Non-IDG -2.39715 256.4 274
Leptin receptor LEPR Tclin Non-IDG -3.01833 782.6 615
G-protein coupled receptor family C group 6 member A GPRC6A Tchem GPCR -1.65243 49.6 172
Interleukin-5 IL5 Tclin Non-IDG -3.45852 2701.9 571
Interferon regulatory factor 1 IRF1 Tbio Transcription Factor -2.90315 827.7 366
Hepatocyte nuclear factor 1-alpha HNF1A Tbio Transcription Factor -2.87439 680.9 0
B-cell CLL/lymphoma 7 protein family member B BCL7B Tbio Non-IDG -0.83317 6.41 180
Polyadenylate-binding protein 4 PABPC4 Tbio Non-IDG -0.92422 8.32 150
Uncharacterized protein C12orf42 C12orf42 Tdark Non-IDG 0.30 0.50 48