Development Level

Tbio 28 | 11,445
Tchem 5 | 1,598
Tdark 2 | 6,588
Tclin 1 | 613

Collection

Kinase: IDG Consortium (Comple... 1 | 37

IMPC Phenotype

preweaning lethality, incomple... 2 | 499
abnormal cranium morphology 1 | 36
abnormal head morphology 1 | 10
decreased circulating LDL chol... 1 | 38
decreased circulating alanine ... 1 | 47
decreased circulating aspartat... 1 | 34
decreased circulating iron lev... 1 | 32
decreased fasted circulating g... 1 | 65
decreased lactate dehydrogenas... 1 | 16
hyperactivity 1 | 148
increased circulating lipase l... 1 | 3
increased grip strength 1 | 41
increased leukocyte cell numbe... 1 | 47
increased mean corpuscular hem... 1 | 96
increased red blood cell distr... 1 | 34
preweaning lethality, complete... 1 | 979

Disease

Carcinoma 27 | 11,493
Breast cancer 26 | 3,578
ovarian cancer 18 | 8,520
atypical teratoid / rhabdoid tumor 17 | 5,112
psoriasis 17 | 6,694
lung cancer 16 | 4,740
Kidney cancer 13 | 2,613
ependymoma 13 | 4,679
medulloblastoma, large-cell 13 | 6,241
glioblastoma 12 | 5,792
lung carcinoma 12 | 2,843
osteosarcoma 12 | 7,950
group 3 medulloblastoma 10 | 4,104
intraductal papillary-mucinous adenoma (IPMA) 10 | 2,955
Astrocytoma, Pilocytic 9 | 3,081
Pick disease 9 | 1,894
intraductal papillary-mucinous carcinoma (IPMC) 9 | 2,989
intraductal papillary-mucinous neoplasm (IPMN) 9 | 3,291
invasive ductal carcinoma 9 | 2,951
non-small cell lung cancer 9 | 2,890
pituitary cancer 9 | 1,972
primitive neuroectodermal tumor 9 | 3,035
interstitial cystitis 8 | 2,312
lung adenocarcinoma 8 | 2,716
malignant mesothelioma 8 | 3,232
oligodendroglioma 8 | 2,850
subependymal giant cell astrocytoma 8 | 2,287
Atopic dermatitis 7 | 952
Cancer 7 | 2,499
adult high grade glioma 7 | 3,801
colon cancer 7 | 1,478
cystic fibrosis 7 | 1,696
ductal carcinoma in situ 7 | 1,745
Autosomal recessive predisposition 6 | 1,442
Schizophrenia 6 | 1,160
Short stature 6 | 531
astrocytic glioma 6 | 2,597
breast carcinoma 6 | 1,638
fibroadenoma 6 | 559
Acquired metabolic disease 5 | 336
Crohn's disease 5 | 321
Melanoma 5 | 711
Obesity 5 | 678
active ulcerative colitis 5 | 764
acute quadriplegic myopathy 5 | 1,158
adrenocortical carcinoma 5 | 1,428
diabetes mellitus 5 | 1,728
pancreatic ductal adenocarcinoma liver metastasis 5 | 1,962
Attention deficit hyperactivity disorder 4 | 278
Bipolar Disorder 4 | 666
Breast Neoplasms 4 | 445
Cognitive delay 4 | 608
Global developmental delay 4 | 608
Hepatomegaly 4 | 285
Hydronephrosis 4 | 89
Hypoplastic mandible condyle 4 | 275
Mammary Neoplasms 4 | 425
Mandibular hypoplasia 4 | 275
Mental Depression 4 | 333
Mental and motor retardation 4 | 608
Micrognathism 4 | 275
Osteoporosis 4 | 363
Small head 4 | 374
Strabismus 4 | 270
Type 2 diabetes mellitus 4 | 272
active Crohn's disease 4 | 922
cutaneous lupus erythematosus 4 | 1,057
juvenile dermatomyositis 4 | 1,187
nasopharyngeal carcinoma 4 | 1,058
pancreatic cancer 4 | 2,398
spina bifida 4 | 1,074
Alzheimer's disease 3 | 658
Amyotrophic lateral sclerosis 3 | 451
Asthma 3 | 385
Byzanthine arch palate 3 | 194
Chronic obstructive pulmonary disease 3 | 184
Depressive disorder 3 | 409
Diabetes Mellitus, Type 2 3 | 142
Endometriosis 3 | 540
Epilepsy 3 | 792
Failure to gain weight 3 | 365
Glaucoma 3 | 239
Hypertrophy of clitoris 3 | 40
Kidney disease 3 | 430
Lung Neoplasms 3 | 232
Mood Disorders 3 | 184
Multiple Sclerosis 3 | 540
Parkinson's disease 3 | 392
Pediatric failure to thrive 3 | 365
Prostatic Neoplasms 3 | 495
Rheumatoid arthritis 3 | 1,191
Seizures 3 | 596
Skin cancer 3 | 469
Stomach Neoplasms 3 | 300
Vascular disease 3 | 319
esophageal adenocarcinoma 3 | 737
sonic hedgehog group medulloblastoma 3 | 467
tuberculosis 3 | 2,010
ulcerative colitis 3 | 1,819
urothelial carcinoma 3 | 318

Tissue

Blood and immune system 34 | 16,909
Cardiovascular System 34 | 15,192
Digestive Tract 34 | 17,369
Endocrine System 34 | 18,159
Female tissues 34 | 17,400
Liver and Pancreas 34 | 16,750
Male tissues 34 | 17,142
Respiratory system 34 | 16,393
Skin and soft tissues 34 | 17,230
Urinary Tract 34 | 16,678
Nervous System 33 | 16,725

Target Family

Non-IDG 27 | 12,091
Enzyme 4 | 4,145
Kinase 2 | 634
Epigenetic 1 | 242
Nuclear Receptor 1 | 48
Transcription Factor 1 | 1,400

GWAS Trait

Breast size 36 | 36
Obesity-related traits 569 | 569
Schizophrenia 533 | 533
Breast cancer 492 | 492
Body mass index 379 | 379
Height 369 | 369
Coronary artery disease 367 | 367
Blood protein levels 351 | 351
Post bronchodilator FEV1-FVC r... 308 | 308
Mean corpuscular volume 283 | 283
Platelet count 275 | 275
Intelligence (multi-trait anal... 267 | 267
Mean platelet volume 253 | 253
IgG glycosylation 250 | 250
Mean corpuscular hemoglobin 238 | 238
Inflammatory bowel disease 235 | 235
Plateletcrit 227 | 227
Crohn's disease 215 | 215
Type 2 diabetes 210 | 210
Red blood cell count 191 | 191
Monocyte count 183 | 183
Red cell distribution width 182 | 182
Eosinophil counts 180 | 180
Neuroticism 180 | 180
Platelet distribution width 174 | 174
Monocyte percentage of white c... 173 | 173
Post bronchodilator FEV1 173 | 173
Sum eosinophil basophil counts 173 | 173
White blood cell count 172 | 172
3-hydroxy-1-methylpropylmercap... 166 | 166
Eosinophil percentage of granu... 163 | 163
Eosinophil percentage of white... 163 | 163
Reticulocyte fraction of red c... 163 | 163
Ulcerative colitis 163 | 163
Granulocyte percentage of myel... 162 | 162
Itch intensity from mosquito b... 162 | 162
Systemic lupus erythematosus 159 | 159
High light scatter reticulocyt... 158 | 158
Lymphocyte counts 158 | 158
Reticulocyte count 158 | 158
Blood metabolite levels 157 | 157
Neutrophil count 154 | 154
High light scatter reticulocyt... 153 | 153
Neutrophil percentage of granu... 153 | 153
3-hydroxypropylmercapturic aci... 150 | 150
Tonsillectomy 149 | 149
Diastolic blood pressure 144 | 144
Sum basophil neutrophil counts 140 | 140
Autism spectrum disorder or sc... 134 | 134
Myeloid white cell count 133 | 133
Granulocyte count 132 | 132
Sum neutrophil eosinophil coun... 129 | 129
Colorectal cancer 126 | 126
Alzheimer disease and age of o... 124 | 124
Multiple sclerosis 124 | 124
Cholesterol, total 123 | 123
Night sleep phenotypes 123 | 123
Lung cancer 122 | 122
Lymphocyte percentage of white... 122 | 122
Menarche (age at onset) 122 | 122
Neutrophil percentage of white... 121 | 121
Rheumatoid arthritis 121 | 121
Systolic blood pressure 120 | 120
Immature fraction of reticuloc... 118 | 118
Diisocyanate-induced asthma 116 | 116
HDL cholesterol 116 | 116
Allergic disease (asthma, hay ... 115 | 115
Educational attainment (years ... 114 | 114
Hematocrit 113 | 113
Hemoglobin concentration 112 | 112
LDL cholesterol 110 | 110
QT interval 110 | 110
Waist circumference adjusted f... 110 | 110
Mosquito bite size 107 | 107
Asthma 106 | 106
Lobe attachment (rater-scored ... 103 | 103
Peripheral arterial disease (t... 101 | 101
Pulse pressure 97 | 97
Bipolar disorder 94 | 94
Major depressive disorder 94 | 94
Prostate cancer 92 | 92
Parkinson's disease 90 | 90
Hip circumference adjusted for... 89 | 89
Metabolite levels 87 | 87
Triglycerides 87 | 87
Colonoscopy-negative controls ... 85 | 85
Mean corpuscular hemoglobin co... 85 | 85
Itch intensity from mosquito b... 84 | 84
Bipolar disorder and schizophr... 83 | 83
Resting heart rate 82 | 82
Macrophage inflammatory protei... 81 | 81
Migraine 81 | 81
Waist-to-hip ratio adjusted fo... 81 | 81
PR interval in Tripanosoma cru... 80 | 80
Cognitive performance 79 | 79
Glomerular filtration rate (cr... 78 | 78
Late-onset Alzheimer's disease 78 | 78
Waist circumference adjusted f... 75 | 75
Tuberculosis 73 | 73
Type 1 diabetes 73 | 73
Morning vs. evening chronotype 72 | 72

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Alpha-1-antitrypsin SERPINA1 Tbio Non-IDG -3.74914 5601.8 1083
Protein lifeguard 2 FAIM2 Tbio Non-IDG -2.37264 234.7 176
Talanin ZNF365 Tbio Non-IDG -1.44015 50.6 273
Protein ZNF365 ZNF365 Tbio Non-IDG -1.44015 50.6 273
Serine/threonine-protein kinase DCLK1 DCLK1 Tchem Kinase -2.08177 129.5 320
Iron-sulfur cluster co-chaperone protein HscB, mitochondrial HSCB Tbio Non-IDG -1.63830 47.3 42
T-box transcription factor TBX15 TBX15 Tbio Transcription Factor -1.29899 21.5 123
Parathyroid hormone-related protein PTHLH Tbio Non-IDG -3.27676 2151.5 283
Coiled-coil domain-containing protein 170 CCDC170 Tbio Non-IDG -0.90555 7.80 85
Oxysterol-binding protein-related protein 6 OSBPL6 Tbio Non-IDG -0.48139 2.36 100