Development Level

Tbio 26 | 11,445
Tchem 5 | 1,598
Tdark 3 | 6,588
Tclin 1 | 613

IMPC Phenotype

preweaning lethality, complete... 3 | 979
abnormal behavior 2 | 298
decreased circulating chloride... 2 | 30
hyperactivity 2 | 148
abnormal bone structure 1 | 187
abnormal coat-hair pigmentatio... 1 | 64
abnormal cranium morphology 1 | 36
abnormal embryo size 1 | 220
abnormal head morphology 1 | 10
absent pinna reflex 1 | 23
decreased body length 1 | 101
decreased circulating HDL chol... 1 | 68
decreased circulating LDL chol... 1 | 38
decreased circulating alanine ... 1 | 47
decreased circulating aspartat... 1 | 34
decreased circulating glucose ... 1 | 126
decreased circulating insulin ... 1 | 76
decreased circulating iron lev... 1 | 32
decreased lactate dehydrogenas... 1 | 16
decreased total body fat amoun... 1 | 207
decreased vertical activity 1 | 208
edema 1 | 59
enlarged heart 1 | 210
improved glucose tolerance 1 | 79
increased bone mineral content 1 | 108
increased circulating HDL chol... 1 | 80
increased circulating choleste... 1 | 66
increased circulating free fat... 1 | 20
increased fasted circulating g... 1 | 76
increased lean body mass 1 | 172
preweaning lethality, incomple... 1 | 499

Disease

Breast cancer 26 | 3,578
Carcinoma 24 | 11,493
ovarian cancer 22 | 8,520
psoriasis 17 | 6,694
osteosarcoma 16 | 7,950
lung cancer 15 | 4,740
Breast Neoplasms 14 | 445
Cancer 13 | 2,499
Mammary Neoplasms 13 | 425
atypical teratoid / rhabdoid tumor 12 | 5,112
glioblastoma 12 | 5,792
malignant mesothelioma 12 | 3,232
group 3 medulloblastoma 11 | 4,104
medulloblastoma, large-cell 11 | 6,241
Astrocytoma, Pilocytic 10 | 3,081
ependymoma 10 | 4,679
primitive neuroectodermal tumor 10 | 3,035
adult high grade glioma 9 | 3,801
intraductal papillary-mucinous adenoma (IPMA) 9 | 2,955
Kidney cancer 8 | 2,613
intraductal papillary-mucinous carcinoma (IPMC) 8 | 2,989
lung adenocarcinoma 8 | 2,716
lung carcinoma 8 | 2,843
oligodendroglioma 8 | 2,850
pituitary cancer 8 | 1,972
Atopic dermatitis 7 | 952
colon cancer 7 | 1,478
intraductal papillary-mucinous neoplasm (IPMN) 7 | 3,291
non-small cell lung cancer 7 | 2,890
pancreatic cancer 7 | 2,398
Acquired metabolic disease 6 | 336
astrocytic glioma 6 | 2,597
cystic fibrosis 6 | 1,696
medulloblastoma 6 | 720
Bipolar Disorder 5 | 666
Melanoma 5 | 711
Osteoporosis 5 | 363
Ovarian Neoplasms 5 | 102
Pick disease 5 | 1,894
Prostate cancer 5 | 175
Prostatic Neoplasms 5 | 495
adrenocortical carcinoma 5 | 1,428
breast carcinoma 5 | 1,638
ductal carcinoma in situ 5 | 1,745
ovarian neoplasm 5 | 99
Autosomal recessive predisposition 4 | 1,442
Carcinoma, Hepatocellular 4 | 228
Colorectal Neoplasms 4 | 243
Crohn's disease 4 | 321
Disease Progression 4 | 136
Glioma 4 | 74
Liver carcinoma 4 | 240
Pancreatic Neoplasm 4 | 85
Pancreatic Neoplasms 4 | 85
Short stature 4 | 531
chronic rhinosinusitis 4 | 512
cystic fibrosis and chronic rhinosinusitis 4 | 214
gastric carcinoma 4 | 807
interstitial cystitis 4 | 2,312
invasive ductal carcinoma 4 | 2,951
juvenile dermatomyositis 4 | 1,187
non-small cell lung carcinoma 4 | 317
ulcerative colitis 4 | 1,819
Adenocarcinoma 3 | 122
Amyotrophic lateral sclerosis 3 | 451
Attention deficit hyperactivity disorder 3 | 278
Bladder Neoplasm 3 | 112
COPD 3 | 118
Cerebellar Ataxia 3 | 304
Cognitive delay 3 | 608
Coronary artery disease 3 | 268
Duchenne muscular dystrophy 3 | 601
Endometrial cancer 3 | 311
Global developmental delay 3 | 608
Leukemia 3 | 104
Liver neoplasms 3 | 130
Lung Neoplasms 3 | 232
Mental Depression 3 | 333
Mental and motor retardation 3 | 608
Multiple myeloma 3 | 1,332
Neoplasm Metastasis 3 | 168
Neuroblastoma 3 | 80
Obesity 3 | 678
Schizophrenia 3 | 1,160
Small head 3 | 374
Urinary Bladder Neoplasms 3 | 114
acute quadriplegic myopathy 3 | 1,158
aldosterone-producing adenoma 3 | 665
cutaneous lupus erythematosus 3 | 1,057
diabetes mellitus 3 | 1,728
fibroadenoma 3 | 559
nasopharyngeal carcinoma 3 | 1,058
posterior fossa group B ependymoma 3 | 416
subependymal giant cell astrocytoma 3 | 2,287
tuberculosis 3 | 2,010
Diabetes Mellitus, Non-Insulin-Dependent 2 | 145
Diabetes Mellitus, Type 2 2 | 142
Epilepsy 2 | 792
Hepatomegaly 2 | 285
pediatric high grade glioma 2 | 1,064

Tissue

Blood and immune system 34 | 16,909
Digestive Tract 34 | 17,369
Endocrine System 34 | 18,159
Female tissues 33 | 17,400
Liver and Pancreas 33 | 16,750
Male tissues 33 | 17,142
Nervous System 33 | 16,725
Respiratory system 33 | 16,393
Skin and soft tissues 33 | 17,230
Urinary Tract 33 | 16,678
Cardiovascular System 31 | 15,192

Target Family

Non-IDG 20 | 12,091
Enzyme 8 | 4,145
Nuclear Receptor 2 | 48
Transcription Factor 2 | 1,400
Epigenetic 1 | 242
GPCR 1 | 408
Ion Channel 1 | 344

GWAS Trait

Breast cancer (estrogen-recept... 35 | 35
Obesity-related traits 569 | 569
Schizophrenia 533 | 533
Breast cancer 492 | 492
Body mass index 379 | 379
Height 369 | 369
Coronary artery disease 367 | 367
Blood protein levels 351 | 351
Post bronchodilator FEV1-FVC r... 308 | 308
Mean corpuscular volume 283 | 283
Platelet count 275 | 275
Intelligence (multi-trait anal... 267 | 267
Mean platelet volume 253 | 253
IgG glycosylation 250 | 250
Mean corpuscular hemoglobin 238 | 238
Inflammatory bowel disease 235 | 235
Plateletcrit 227 | 227
Crohn's disease 215 | 215
Type 2 diabetes 210 | 210
Red blood cell count 191 | 191
Monocyte count 183 | 183
Red cell distribution width 182 | 182
Eosinophil counts 180 | 180
Neuroticism 180 | 180
Platelet distribution width 174 | 174
Monocyte percentage of white c... 173 | 173
Post bronchodilator FEV1 173 | 173
Sum eosinophil basophil counts 173 | 173
White blood cell count 172 | 172
3-hydroxy-1-methylpropylmercap... 166 | 166
Eosinophil percentage of granu... 163 | 163
Eosinophil percentage of white... 163 | 163
Reticulocyte fraction of red c... 163 | 163
Ulcerative colitis 163 | 163
Granulocyte percentage of myel... 162 | 162
Itch intensity from mosquito b... 162 | 162
Systemic lupus erythematosus 159 | 159
High light scatter reticulocyt... 158 | 158
Lymphocyte counts 158 | 158
Reticulocyte count 158 | 158
Blood metabolite levels 157 | 157
Neutrophil count 154 | 154
High light scatter reticulocyt... 153 | 153
Neutrophil percentage of granu... 153 | 153
3-hydroxypropylmercapturic aci... 150 | 150
Tonsillectomy 149 | 149
Diastolic blood pressure 144 | 144
Sum basophil neutrophil counts 140 | 140
Autism spectrum disorder or sc... 134 | 134
Myeloid white cell count 133 | 133
Granulocyte count 132 | 132
Sum neutrophil eosinophil coun... 129 | 129
Colorectal cancer 126 | 126
Alzheimer disease and age of o... 124 | 124
Multiple sclerosis 124 | 124
Cholesterol, total 123 | 123
Night sleep phenotypes 123 | 123
Lung cancer 122 | 122
Lymphocyte percentage of white... 122 | 122
Menarche (age at onset) 122 | 122
Neutrophil percentage of white... 121 | 121
Rheumatoid arthritis 121 | 121
Systolic blood pressure 120 | 120
Immature fraction of reticuloc... 118 | 118
Diisocyanate-induced asthma 116 | 116
HDL cholesterol 116 | 116
Allergic disease (asthma, hay ... 115 | 115
Educational attainment (years ... 114 | 114
Hematocrit 113 | 113
Hemoglobin concentration 112 | 112
LDL cholesterol 110 | 110
QT interval 110 | 110
Waist circumference adjusted f... 110 | 110
Mosquito bite size 107 | 107
Asthma 106 | 106
Lobe attachment (rater-scored ... 103 | 103
Peripheral arterial disease (t... 101 | 101
Pulse pressure 97 | 97
Bipolar disorder 94 | 94
Major depressive disorder 94 | 94
Prostate cancer 92 | 92
Parkinson's disease 90 | 90
Hip circumference adjusted for... 89 | 89
Metabolite levels 87 | 87
Triglycerides 87 | 87
Colonoscopy-negative controls ... 85 | 85
Mean corpuscular hemoglobin co... 85 | 85
Itch intensity from mosquito b... 84 | 84
Bipolar disorder and schizophr... 83 | 83
Resting heart rate 82 | 82
Macrophage inflammatory protei... 81 | 81
Migraine 81 | 81
Waist-to-hip ratio adjusted fo... 81 | 81
PR interval in Tripanosoma cru... 80 | 80
Cognitive performance 79 | 79
Glomerular filtration rate (cr... 78 | 78
Late-onset Alzheimer's disease 78 | 78
Waist circumference adjusted f... 75 | 75
Tuberculosis 73 | 73
Type 1 diabetes 73 | 73
Morning vs. evening chronotype 72 | 72

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Parathyroid hormone-related protein PTHLH Tbio Non-IDG -3.27676 2151.5 283
Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 12 protein ALS2CR12 Tdark Non-IDG -0.60669 3.75 40
Breast cancer type 2 susceptibility protein BRCA2 Tbio Non-IDG -3.46139 2647.6 209
Talanin ZNF365 Tbio Non-IDG -1.44015 50.6 273
Protein ZNF365 ZNF365 Tbio Non-IDG -1.44015 50.6 273
Intermediate conductance calcium-activated potassium channel protein 4 KCNN4 Tchem Ion Channel -2.44473 312.3 199
Ankyrin repeat and LEM domain-containing protein 1 ANKLE1 Tbio Non-IDG -1.22574 16.7 31
Cadherin-2 CDH2 Tbio Non-IDG -3.19431 1382.9 993
Nesprin-1 SYNE1 Tbio Non-IDG -2.28105 171.4 65
Coiled-coil domain-containing protein 170 CCDC170 Tbio Non-IDG -0.90555 7.80 85