Development Level

Tbio 320 | 11,178
Tdark 90 | 6,569
Tchem 67 | 1,885
Tclin 15 | 612

Collection

Kinase: IDG Consortium (Target... 3 | 125
Kinase: IDG Consortium (Comple... 2 | 37
GPCR: IDG Consortium (Complete... 1 | 25

IMPC Phenotype

preweaning lethality, incomple... 28 | 499
preweaning lethality, complete... 21 | 979
cataract 8 | 92
decreased body weight 8 | 161
decreased total body fat amoun... 8 | 207
enlarged heart 8 | 210
hyperactivity 8 | 148
short tibia 8 | 97
abnormal behavior 7 | 298
decreased circulating choleste... 7 | 93
abnormal embryo size 6 | 220
abnormal heart morphology 6 | 162
decreased circulating glucose ... 6 | 126
increased circulating HDL chol... 6 | 80
increased total body fat amoun... 6 | 134
abnormal lens morphology 5 | 81
decreased body length 5 | 101
decreased circulating HDL chol... 5 | 68
increased bone mineral content 5 | 108
increased circulating choleste... 5 | 66
abnormal coat-hair pigmentatio... 4 | 64
abnormal seminal vesicle morph... 4 | 114
decreased circulating LDL chol... 4 | 38
decreased lean body mass 4 | 135
impaired pupillary reflex 4 | 26
increased or absent threshold ... 4 | 101
male infertility 4 | 123
abnormal bone structure 3 | 187
abnormal cornea morphology 3 | 31
abnormal cranium morphology 3 | 36
abnormal gait 3 | 69
abnormal lung morphology 3 | 26
abnormal neural tube closure 3 | 46
abnormal spleen morphology 3 | 55
corneal opacity 3 | 32
decreased circulating alanine ... 3 | 47
decreased circulating aspartat... 3 | 34
decreased circulating calcium ... 3 | 36
decreased circulating chloride... 3 | 30
decreased grip strength 3 | 116
decreased lymphocyte cell numb... 3 | 83
decreased vertical activity 3 | 208
embryonic growth retardation 3 | 106
enlarged spleen 3 | 41
increased bone mineral density 3 | 72
increased circulating sodium l... 3 | 71
increased lean body mass 3 | 172
increased startle reflex 3 | 112
abnormal chorioallantoic fusio... 2 | 8
abnormal embryo turning 2 | 31
abnormal epididymis morphology 2 | 42
abnormal eye morphology 2 | 68
abnormal head morphology 2 | 10
abnormal locomotor activation 2 | 16
abnormal testis morphology 2 | 43
cardiovascular system phenotyp... 2 | 36
decreased bone mineral content 2 | 151
decreased bone mineral density 2 | 126
decreased circulating fructosa... 2 | 30
decreased circulating insulin ... 2 | 76
decreased circulating phosphat... 2 | 27
decreased circulating total pr... 2 | 49
decreased heart rate 2 | 18
decreased lactate dehydrogenas... 2 | 16
decreased mean corpuscular hem... 2 | 50
decreased mean corpuscular vol... 2 | 79
decreased startle reflex 2 | 75
edema 2 | 59
embryonic lethality prior to o... 2 | 239
embryonic lethality prior to t... 2 | 278
enlarged epididymis 2 | 31
female infertility 2 | 60
hydrometra 2 | 53
hypoactivity 2 | 132
increased circulating alkaline... 2 | 122
increased circulating chloride... 2 | 41
increased erythrocyte cell num... 2 | 39
increased fasted circulating g... 2 | 76
increased grip strength 2 | 41
increased monocyte cell number 2 | 63
limb grasping 2 | 41
long tibia 2 | 25
mydriasis 2 | 6
narrow eye opening 2 | 12
small superior vagus ganglion 2 | 74
small testis 2 | 58
vertebral transformation 2 | 12
abnormal behavioral response t... 1 | 66
abnormal craniofacial morpholo... 1 | 33
abnormal heart looping 1 | 5
abnormal tooth morphology 1 | 24
abnormal vocalization 1 | 21
decreased circulating amylase ... 1 | 28
decreased circulating triglyce... 1 | 79
decreased red blood cell distr... 1 | 41
decreased total retina thickne... 1 | 17
increased body length 1 | 32
increased circulating magnesiu... 1 | 10
persistence of hyaloid vascula... 1 | 33
vertebral fusion 1 | 23

Disease

Carcinoma 365 | 11,192
ovarian cancer 249 | 8,297
osteosarcoma 244 | 7,766
medulloblastoma, large-cell 220 | 6,086
glioblastoma 206 | 5,635
psoriasis 196 | 6,514
Breast cancer 182 | 3,469
atypical teratoid / rhabdoid tumor 179 | 4,971
ependymoma 162 | 4,559
lung cancer 156 | 4,607
group 3 medulloblastoma 143 | 4,002
adult high grade glioma 123 | 3,701
Kidney cancer 121 | 2,548
malignant mesothelioma 112 | 3,135
primitive neuroectodermal tumor 108 | 2,957
Astrocytoma, Pilocytic 106 | 3,006
invasive ductal carcinoma 106 | 2,867
intraductal papillary-mucinous adenoma (IPMA) 105 | 2,872
oligodendroglioma 105 | 2,768
lung carcinoma 104 | 2,755
intraductal papillary-mucinous neoplasm (IPMN) 102 | 3,204
intraductal papillary-mucinous carcinoma (IPMC) 101 | 2,902
Cancer 93 | 2,388
non-small cell lung cancer 91 | 2,799
lung adenocarcinoma 90 | 2,627
astrocytic glioma 85 | 2,530
pancreatic cancer 83 | 2,322
pituitary cancer 79 | 1,915
subependymal giant cell astrocytoma 76 | 2,230
interstitial cystitis 73 | 2,237
Pick disease 72 | 1,856
tuberculosis 70 | 1,963
group 4 medulloblastoma 64 | 1,806
breast carcinoma 61 | 1,589
cystic fibrosis 59 | 1,629
ulcerative colitis 58 | 1,765
ductal carcinoma in situ 55 | 1,686
adrenocortical carcinoma 54 | 1,385
colon cancer 53 | 1,428
juvenile dermatomyositis 51 | 1,147
pancreatic ductal adenocarcinoma liver metastasis 49 | 1,911
Schizophrenia 48 | 1,136
Autosomal recessive predisposition 44 | 1,407
acute quadriplegic myopathy 44 | 1,133
astrocytoma 42 | 1,113
Breast Neoplasms 41 | 423
spina bifida 41 | 1,053
Mammary Neoplasms 40 | 403
Melanoma 40 | 689
Rheumatoid arthritis 40 | 1,156
gastric carcinoma 40 | 781
nasopharyngeal carcinoma 40 | 1,024
Bipolar Disorder 39 | 646
Multiple myeloma 37 | 1,296
diabetes mellitus 37 | 1,683
primary pancreatic ductal adenocarcinoma 37 | 1,071
pediatric high grade glioma 36 | 1,035
Acquired metabolic disease 35 | 329
cutaneous lupus erythematosus 35 | 1,016
active ulcerative colitis 33 | 736
Intellectual disability 32 | 998
Atopic dermatitis 31 | 915
Liver cancer 31 | 589
dermatomyositis 31 | 941
autosomal dominant Emery-Dreifuss muscular dystrophy 30 | 492
Amyotrophic lateral sclerosis 29 | 437
Prostatic Neoplasms 29 | 472
active Crohn's disease 28 | 882
Epilepsy 27 | 775
non primary Sjogren syndrome sicca 27 | 861
Duchenne muscular dystrophy 26 | 587
Obesity 26 | 655
Short stature 26 | 514
Muscle hypotonia 25 | 562
progressive supranuclear palsy 25 | 656
Dull intelligence 24 | 634
Liver Cirrhosis, Experimental 24 | 733
Low intelligence 24 | 634
Mental Retardation 24 | 634
Mental deficiency 24 | 634
Poor school performance 24 | 634
Crohn's disease 23 | 311
Skin cancer 23 | 451
Endometriosis 22 | 521
Neurodegenerative disease 22 | 402
esophageal adenocarcinoma 22 | 696
posterior fossa group A ependymoma 22 | 456
Prostate cancer 21 | 164
medulloblastoma 21 | 702
Depressive disorder 20 | 401
Endometrial cancer 20 | 301
Hypoplastic mandible condyle 20 | 273
Mandibular hypoplasia 20 | 273
Micrognathism 20 | 273
acute myeloid leukemia 20 | 760
pancreatic carcinoma 20 | 555
Alzheimer's disease 19 | 640
aldosterone-producing adenoma 19 | 646
hepatocellular carcinoma 19 | 536
primary Sjogren syndrome 19 | 710

Tissue

Endocrine System 480 | 18,159
Digestive Tract 468 | 17,369
Female tissues 465 | 17,400
Male tissues 465 | 17,142
Skin and soft tissues 465 | 17,230
Nervous System 464 | 16,725
Liver and Pancreas 462 | 16,750
Urinary Tract 461 | 16,678
Blood and immune system 459 | 16,909
Respiratory system 458 | 16,393
Cardiovascular System 419 | 15,192

Target Family

Non-IDG 260 | 12,091
Enzyme 105 | 4,145
Transcription Factor 54 | 1,400
Kinase 22 | 634
Transporter 17 | 473
Epigenetic 15 | 242
GPCR 6 | 408
Ion Channel 5 | 344
Nuclear Receptor 4 | 48
TF/Epigenetic 2 | 38
oGPCR 2 | 421

GWAS Trait

Breast cancer 492 | 492
Obesity-related traits 569 | 569
Schizophrenia 533 | 533
Body mass index 379 | 379
Height 369 | 369
Coronary artery disease 367 | 367
Blood protein levels 351 | 351
Post bronchodilator FEV1-FVC r... 308 | 308
Mean corpuscular volume 283 | 283
Platelet count 275 | 275
Intelligence (multi-trait anal... 267 | 267
Mean platelet volume 253 | 253
IgG glycosylation 250 | 250
Mean corpuscular hemoglobin 238 | 238
Inflammatory bowel disease 235 | 235
Plateletcrit 227 | 227
Crohn's disease 215 | 215
Type 2 diabetes 210 | 210
Red blood cell count 191 | 191
Monocyte count 183 | 183
Red cell distribution width 182 | 182
Eosinophil counts 180 | 180
Neuroticism 180 | 180
Platelet distribution width 174 | 174
Monocyte percentage of white c... 173 | 173
Post bronchodilator FEV1 173 | 173
Sum eosinophil basophil counts 173 | 173
White blood cell count 172 | 172
3-hydroxy-1-methylpropylmercap... 166 | 166
Eosinophil percentage of granu... 163 | 163
Eosinophil percentage of white... 163 | 163
Reticulocyte fraction of red c... 163 | 163
Ulcerative colitis 163 | 163
Granulocyte percentage of myel... 162 | 162
Itch intensity from mosquito b... 162 | 162
Systemic lupus erythematosus 159 | 159
High light scatter reticulocyt... 158 | 158
Lymphocyte counts 158 | 158
Reticulocyte count 158 | 158
Blood metabolite levels 157 | 157
Neutrophil count 154 | 154
High light scatter reticulocyt... 153 | 153
Neutrophil percentage of granu... 153 | 153
3-hydroxypropylmercapturic aci... 150 | 150
Tonsillectomy 149 | 149
Diastolic blood pressure 144 | 144
Sum basophil neutrophil counts 140 | 140
Autism spectrum disorder or sc... 134 | 134
Myeloid white cell count 133 | 133
Granulocyte count 132 | 132
Sum neutrophil eosinophil coun... 129 | 129
Colorectal cancer 126 | 126
Alzheimer disease and age of o... 124 | 124
Multiple sclerosis 124 | 124
Cholesterol, total 123 | 123
Night sleep phenotypes 123 | 123
Lung cancer 122 | 122
Lymphocyte percentage of white... 122 | 122
Menarche (age at onset) 122 | 122
Neutrophil percentage of white... 121 | 121
Rheumatoid arthritis 121 | 121
Systolic blood pressure 120 | 120
Immature fraction of reticuloc... 118 | 118
Diisocyanate-induced asthma 116 | 116
HDL cholesterol 116 | 116
Allergic disease (asthma, hay ... 115 | 115
Educational attainment (years ... 114 | 114
Hematocrit 113 | 113
Hemoglobin concentration 112 | 112
LDL cholesterol 110 | 110
QT interval 110 | 110
Waist circumference adjusted f... 110 | 110
Mosquito bite size 107 | 107
Asthma 106 | 106
Lobe attachment (rater-scored ... 103 | 103
Peripheral arterial disease (t... 101 | 101
Pulse pressure 97 | 97
Bipolar disorder 94 | 94
Major depressive disorder 94 | 94
Prostate cancer 92 | 92
Parkinson's disease 90 | 90
Hip circumference adjusted for... 89 | 89
Metabolite levels 87 | 87
Triglycerides 87 | 87
Colonoscopy-negative controls ... 85 | 85
Mean corpuscular hemoglobin co... 85 | 85
Itch intensity from mosquito b... 84 | 84
Bipolar disorder and schizophr... 83 | 83
Resting heart rate 82 | 82
Macrophage inflammatory protei... 81 | 81
Migraine 81 | 81
Waist-to-hip ratio adjusted fo... 81 | 81
PR interval in Tripanosoma cru... 80 | 80
Cognitive performance 79 | 79
Glomerular filtration rate (cr... 78 | 78
Late-onset Alzheimer's disease 78 | 78
Waist circumference adjusted f... 75 | 75
Tuberculosis 73 | 73
Type 1 diabetes 73 | 73
Morning vs. evening chronotype 72 | 72

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
BAH and coiled-coil domain-containing protein 1 BAHCC1 Tbio Non-IDG 0.00000 0
Putative uncharacterized protein encoded by LINC00869 LINC00869 Tdark Non-IDG 0.00000 0
Serine protease inhibitor Kazal-type 8 SPINK8 Tdark Enzyme 0.00000 1.00 59
Protein AF-10 MLLT10 Tbio Epigenetic -2.11577 137.2 264
Embigin EMB Tbio Non-IDG -2.79800 638.6 103
DNA-directed RNA polymerase I subunit RPA12 ZNRD1 Tbio Enzyme -1.56141 38.0 76
Adenylate cyclase type 3 ADCY3 Tbio Enzyme -2.31593 204.4 82
Heat shock 70 kDa protein 4 HSPA4 Tbio Non-IDG -3.92672 8635.1 432
Rho guanine nucleotide exchange factor 28 ARHGEF28 Tbio Non-IDG -1.62506 29.7 18
Neuronal regeneration-related protein NREP Tbio Non-IDG -1.41324 21.8 71