Development Level

Tbio 43 | 11,445
Tchem 8 | 1,598
Tdark 7 | 6,588
Tclin 2 | 613

Collection

RFA-RM-18-021 2 | 328
Ion Channel: IDG Consortium (T... 1 | 99
Kinase: IDG Consortium (Target... 1 | 125

IMPC Phenotype

preweaning lethality, complete... 8 | 979
decreased total body fat amoun... 4 | 207
abnormal behavior 3 | 298
increased lean body mass 3 | 172
decreased body length 2 | 101
decreased circulating LDL chol... 2 | 38
decreased circulating choleste... 2 | 93
embryonic lethality prior to t... 2 | 278
hyperactivity 2 | 148
increased bone mineral content 2 | 108
abnormal embryo size 1 | 220
abnormal joint morphology 1 | 23
abnormal tail movements 1 | 12
absent startle reflex 1 | 24
brachydactyly 1 | 19
cataract 1 | 92
decreased bone mineral content 1 | 151
decreased circulating HDL chol... 1 | 68
decreased circulating alanine ... 1 | 47
decreased circulating alkaline... 1 | 46
decreased circulating aspartat... 1 | 34
decreased circulating iron lev... 1 | 32
decreased food intake 1 | 13
decreased grip strength 1 | 116
decreased heart weight 1 | 27
decreased lactate dehydrogenas... 1 | 16
decreased mean corpuscular vol... 1 | 79
embryonic lethality prior to o... 1 | 239
enlarged kidney 1 | 14
enlarged lymph nodes 1 | 37
hypoactivity 1 | 132
increased blood urea nitrogen ... 1 | 48
increased body weight 1 | 25
increased bone mineral density 1 | 72
increased circulating creatini... 1 | 38
increased circulating potassiu... 1 | 29
increased exploration in new e... 1 | 8
increased leukocyte cell numbe... 1 | 47
increased lymphocyte cell numb... 1 | 32
increased mean corpuscular hem... 1 | 96
increased total body fat amoun... 1 | 134
male infertility 1 | 123
prenatal lethality prior to he... 1 | 87
preweaning lethality, incomple... 1 | 499
syndactyly 1 | 23
thrombocytopenia 1 | 56
thrombocytosis 1 | 27
unresponsive to tactile stimul... 1 | 8

Disease

Carcinoma 45 | 11,493
osteosarcoma 33 | 7,950
ovarian cancer 31 | 8,520
Acquired metabolic disease 28 | 336
medulloblastoma, large-cell 26 | 6,241
psoriasis 26 | 6,694
glioblastoma 25 | 5,792
atypical teratoid / rhabdoid tumor 23 | 5,112
Breast cancer 19 | 3,578
ependymoma 19 | 4,679
Astrocytoma, Pilocytic 18 | 3,081
adult high grade glioma 17 | 3,801
Kidney cancer 16 | 2,613
group 3 medulloblastoma 16 | 4,104
Obesity 15 | 678
lung cancer 15 | 4,740
lung carcinoma 14 | 2,843
malignant mesothelioma 14 | 3,232
intraductal papillary-mucinous neoplasm (IPMN) 12 | 3,291
primitive neuroectodermal tumor 12 | 3,035
Cancer 11 | 2,499
intraductal papillary-mucinous carcinoma (IPMC) 11 | 2,989
oligodendroglioma 11 | 2,850
Schizophrenia 10 | 1,160
astrocytic glioma 10 | 2,597
intraductal papillary-mucinous adenoma (IPMA) 10 | 2,955
lung adenocarcinoma 10 | 2,716
pancreatic cancer 10 | 2,398
Pick disease 9 | 1,894
invasive ductal carcinoma 9 | 2,951
pituitary cancer 9 | 1,972
subependymal giant cell astrocytoma 9 | 2,287
diabetes mellitus 8 | 1,728
group 4 medulloblastoma 7 | 1,855
interstitial cystitis 7 | 2,312
Autistic Disorder 6 | 364
Autosomal recessive predisposition 6 | 1,442
Melanoma 6 | 711
astrocytoma 6 | 1,146
non-small cell lung cancer 6 | 2,890
pancreatic ductal adenocarcinoma liver metastasis 6 | 1,962
pediatric high grade glioma 6 | 1,064
Bipolar Disorder 5 | 666
Cardiovascular system disease 5 | 246
Depressive disorder 5 | 409
Dull intelligence 5 | 645
Intellectual disability 5 | 1,016
Liver cancer 5 | 604
Low intelligence 5 | 645
Mental Retardation 5 | 645
Mental deficiency 5 | 645
Poor school performance 5 | 645
Rheumatoid arthritis 5 | 1,191
Short stature 5 | 531
aldosterone-producing adenoma 5 | 665
colon cancer 5 | 1,478
cystic fibrosis 5 | 1,696
ductal carcinoma in situ 5 | 1,745
Alzheimer's disease 4 | 658
Amphetamine-Related Disorders 4 | 74
Amyotrophic lateral sclerosis 4 | 451
Body Weight 4 | 14
Epilepsy 4 | 792
Mental Depression 4 | 333
Proteinuria 4 | 144
Skin cancer 4 | 469
Type 2 diabetes mellitus 4 | 272
juvenile dermatomyositis 4 | 1,187
primary pancreatic ductal adenocarcinoma 4 | 1,109
spina bifida 4 | 1,074
tuberculosis 4 | 2,010
ulcerative colitis 4 | 1,819
Alcoholic Intoxication, Chronic 3 | 289
Attention deficit hyperactivity disorder 3 | 278
Chronic obstructive pulmonary disease 3 | 184
Cognitive disorder 3 | 50
Diabetes Mellitus, Type 2 3 | 142
Endometriosis 3 | 540
Essential Hypertension 3 | 94
Kidney Failure 3 | 111
Low Vision 3 | 174
Mood Disorders 3 | 184
Myopia 3 | 176
Neurodevelopmental Disorders 3 | 70
Neuropathy 3 | 261
Orofacial cleft 3 | 54
Polycystic ovary syndrome 3 | 360
Prostatic Neoplasms 3 | 495
Renal Insufficiency 3 | 90
Renal failure in adulthood 3 | 76
Seizures 3 | 596
Stomach Neoplasms 3 | 300
Substance-Related Disorders 3 | 115
Visual Impairment 3 | 174
gastric carcinoma 3 | 807
hereditary spastic paraplegia 3 | 318
medulloblastoma 3 | 720
mucosa-associated lymphoid tissue lymphoma 3 | 484
sonic hedgehog group medulloblastoma 3 | 467
substance-related disorder 3 | 162

Tissue

Endocrine System 59 | 18,159
Female tissues 59 | 17,400
Nervous System 59 | 16,725
Digestive Tract 58 | 17,369
Male tissues 58 | 17,142
Respiratory system 58 | 16,393
Skin and soft tissues 58 | 17,230
Liver and Pancreas 57 | 16,750
Urinary Tract 56 | 16,678
Blood and immune system 55 | 16,909
Cardiovascular System 55 | 15,192

Target Family

Non-IDG 30 | 12,091
Enzyme 13 | 4,145
Kinase 5 | 634
Transcription Factor 4 | 1,400
Epigenetic 2 | 242
Nuclear Receptor 2 | 48
Transporter 2 | 473
GPCR 1 | 408
Ion Channel 1 | 344

GWAS Trait

Body mass index (joint analysi... 60 | 60
Obesity-related traits 569 | 569
Schizophrenia 533 | 533
Breast cancer 492 | 492
Body mass index 379 | 379
Height 369 | 369
Coronary artery disease 367 | 367
Blood protein levels 351 | 351
Post bronchodilator FEV1-FVC r... 308 | 308
Mean corpuscular volume 283 | 283
Platelet count 275 | 275
Intelligence (multi-trait anal... 267 | 267
Mean platelet volume 253 | 253
IgG glycosylation 250 | 250
Mean corpuscular hemoglobin 238 | 238
Inflammatory bowel disease 235 | 235
Plateletcrit 227 | 227
Crohn's disease 215 | 215
Type 2 diabetes 210 | 210
Red blood cell count 191 | 191
Monocyte count 183 | 183
Red cell distribution width 182 | 182
Eosinophil counts 180 | 180
Neuroticism 180 | 180
Platelet distribution width 174 | 174
Monocyte percentage of white c... 173 | 173
Post bronchodilator FEV1 173 | 173
Sum eosinophil basophil counts 173 | 173
White blood cell count 172 | 172
3-hydroxy-1-methylpropylmercap... 166 | 166
Eosinophil percentage of granu... 163 | 163
Eosinophil percentage of white... 163 | 163
Reticulocyte fraction of red c... 163 | 163
Ulcerative colitis 163 | 163
Granulocyte percentage of myel... 162 | 162
Itch intensity from mosquito b... 162 | 162
Systemic lupus erythematosus 159 | 159
High light scatter reticulocyt... 158 | 158
Lymphocyte counts 158 | 158
Reticulocyte count 158 | 158
Blood metabolite levels 157 | 157
Neutrophil count 154 | 154
High light scatter reticulocyt... 153 | 153
Neutrophil percentage of granu... 153 | 153
3-hydroxypropylmercapturic aci... 150 | 150
Tonsillectomy 149 | 149
Diastolic blood pressure 144 | 144
Sum basophil neutrophil counts 140 | 140
Autism spectrum disorder or sc... 134 | 134
Myeloid white cell count 133 | 133
Granulocyte count 132 | 132
Sum neutrophil eosinophil coun... 129 | 129
Colorectal cancer 126 | 126
Alzheimer disease and age of o... 124 | 124
Multiple sclerosis 124 | 124
Cholesterol, total 123 | 123
Night sleep phenotypes 123 | 123
Lung cancer 122 | 122
Lymphocyte percentage of white... 122 | 122
Menarche (age at onset) 122 | 122
Neutrophil percentage of white... 121 | 121
Rheumatoid arthritis 121 | 121
Systolic blood pressure 120 | 120
Immature fraction of reticuloc... 118 | 118
Diisocyanate-induced asthma 116 | 116
HDL cholesterol 116 | 116
Allergic disease (asthma, hay ... 115 | 115
Educational attainment (years ... 114 | 114
Hematocrit 113 | 113
Hemoglobin concentration 112 | 112
LDL cholesterol 110 | 110
QT interval 110 | 110
Waist circumference adjusted f... 110 | 110
Mosquito bite size 107 | 107
Asthma 106 | 106
Lobe attachment (rater-scored ... 103 | 103
Peripheral arterial disease (t... 101 | 101
Pulse pressure 97 | 97
Bipolar disorder 94 | 94
Major depressive disorder 94 | 94
Prostate cancer 92 | 92
Parkinson's disease 90 | 90
Hip circumference adjusted for... 89 | 89
Metabolite levels 87 | 87
Triglycerides 87 | 87
Colonoscopy-negative controls ... 85 | 85
Mean corpuscular hemoglobin co... 85 | 85
Itch intensity from mosquito b... 84 | 84
Bipolar disorder and schizophr... 83 | 83
Resting heart rate 82 | 82
Macrophage inflammatory protei... 81 | 81
Migraine 81 | 81
Waist-to-hip ratio adjusted fo... 81 | 81
PR interval in Tripanosoma cru... 80 | 80
Cognitive performance 79 | 79
Glomerular filtration rate (cr... 78 | 78
Late-onset Alzheimer's disease 78 | 78
Waist circumference adjusted f... 75 | 75
Tuberculosis 73 | 73
Type 1 diabetes 73 | 73
Morning vs. evening chronotype 72 | 72

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Neurexin-3-beta NRXN3 Tbio Non-IDG -1.34072 34.8 172
Importin-9 IPO9 Tbio Non-IDG -1.14983 12.2 108
Neurexin-3 NRXN3 Tbio Non-IDG -1.34072 34.8 172
Paired box protein Pax-2 PAX2 Tbio Transcription Factor -2.68609 492.0 349
A disintegrin and metalloproteinase with thrombospondin motifs 7 ADAMTS7 Tbio Enzyme -1.43732 33.7 98
Glutaminyl-peptide cyclotransferase-like protein QPCTL Tchem Enzyme -1.04298 11.4 85
Mitochondrial carrier homolog 2 MTCH2 Tbio Non-IDG -1.67923 50.3 155
ELAV-like protein 4 ELAVL4 Tbio Non-IDG -2.53162 344.8 186
DnaJ homolog subfamily C member 27 DNAJC27 Tbio Non-IDG -0.92891 8.98 106
BTB/POZ domain-containing protein KCTD15 KCTD15 Tbio Non-IDG -1.04860 11.7 176