Development Level

Tbio 7 | 11,445
Tdark 6 | 6,588

IMPC Phenotype

decreased circulating LDL chol... 2 | 38
abnormal chorioallantoic fusio... 1 | 8
abnormal embryo size 1 | 220
abnormal embryo turning 1 | 31
abnormal heart morphology 1 | 162
abnormal neural tube closure 1 | 46
decreased circulating HDL chol... 1 | 68
decreased circulating alanine ... 1 | 47
decreased circulating aspartat... 1 | 34
decreased circulating choleste... 1 | 93
decreased circulating iron lev... 1 | 32
decreased lactate dehydrogenas... 1 | 16
embryonic growth retardation 1 | 106
embryonic lethality prior to o... 1 | 239
hyperactivity 1 | 148
impaired pupillary reflex 1 | 26
preweaning lethality, complete... 1 | 979

Disease

Carcinoma 10 | 11,493
Acquired metabolic disease 7 | 336
osteosarcoma 7 | 7,950
Obesity 6 | 678
ovarian cancer 6 | 8,520
atypical teratoid / rhabdoid tumor 5 | 5,112
medulloblastoma, large-cell 5 | 6,241
Breast cancer 4 | 3,578
ependymoma 4 | 4,679
glioblastoma 4 | 5,792
group 4 medulloblastoma 4 | 1,855
Astrocytoma, Pilocytic 3 | 3,081
Body Weight 3 | 14
Mood Disorders 3 | 184
adult high grade glioma 3 | 3,801
lung adenocarcinoma 3 | 2,716
pituitary cancer 3 | 1,972
Alcoholic Intoxication, Chronic 2 | 289
Bipolar Disorder 2 | 666
Cancer 2 | 2,499
Depressive disorder 2 | 409
Diabetes Mellitus, Type 2 2 | 142
Mental Depression 2 | 333
Obesity, Morbid 2 | 7
Schizophrenia 2 | 1,160
Type 2 diabetes mellitus 2 | 272
astrocytic glioma 2 | 2,597
diabetes mellitus 2 | 1,728
interstitial cystitis 2 | 2,312
obsessive-compulsive disorder 2 | 61
pediatric high grade glioma 2 | 1,064
primitive neuroectodermal tumor 2 | 3,035
psoriasis 2 | 6,694
subependymal giant cell astrocytoma 2 | 2,287
Alcohol dependence 1 | 107
Alcoholic Intoxication 1 | 34
Alzheimer Disease 1 | 83
Amnestic disorder 1 | 35
Amyotrophic lateral sclerosis 1 | 451
Autism Spectrum Disorders 1 | 75
Autistic Disorder 1 | 364
Barrett's esophagus 1 | 182
Blepharoptosis 1 | 231
Body Temperature Changes 1 | 10
Brain Injuries 1 | 65
Breast Neoplasms 1 | 445
Bulimia nervosa 1 | 14
Cocaine-Related Disorders 1 | 92
Constipation 1 | 181
Deafness 1 | 198
Dementia 1 | 175
Diabetic Angiopathies 1 | 16
Diabetic retinopathy 1 | 56
Downward slant of palpebral fissure 1 | 158
Dyschezia 1 | 135
Eating disorder 1 | 26
Everted lower lip vermilion 1 | 54
Fragile X syndrome 1 | 34
Ganglioneuroma 1 | 13
Generalized anxiety disorder 1 | 29
Gilles de la Tourette syndrome 1 | 47
Gliosis 1 | 56
Hearing abnormality 1 | 12
Heroin dependence 1 | 30
Hirschsprung Disease 1 | 31
Huntington's disease 1 | 76
Hyperhidrosis disorder 1 | 81
Hypoxia 1 | 33
Increased sweating 1 | 81
Inflammation 1 | 120
Low Vision 1 | 174
Lymphoid leukemia 1 | 160
Major Depressive Disorder 1 | 301
Mammary Neoplasms 1 | 425
Megacolon 1 | 29
Melanoma 1 | 711
Metabolic syndrome X 1 | 52
Nerve Degeneration 1 | 121
Nervous System Diseases 1 | 53
Neuropathy 1 | 261
Osteoarthritis 1 | 184
Panic disorder 1 | 61
Parkinson Disease 1 | 64
Parkinson's disease 1 | 392
Poor temperature regulation 1 | 10
Protruding lower lip 1 | 54
Renal agenesis 1 | 29
Retinal Degeneration 1 | 106
Sensorineural hearing loss 1 | 106
Stomach Neoplasms 1 | 300
Substance Withdrawal Syndrome 1 | 55
Sweating 1 | 81
Tonic-clonic epilepsy 1 | 47
Toxic encephalopathy 1 | 141
Visual Impairment 1 | 174
Weight Gain 1 | 100
interstitial lung disease 1 | 298
nervous system disorder 1 | 53
post-traumatic stress disorder 1 | 40
posterior fossa group B ependymoma 1 | 416

Tissue

Endocrine System 13 | 18,159
Blood and immune system 12 | 16,909
Cardiovascular System 12 | 15,192
Digestive Tract 12 | 17,369
Female tissues 12 | 17,400
Liver and Pancreas 12 | 16,750
Male tissues 12 | 17,142
Nervous System 12 | 16,725
Respiratory system 12 | 16,393
Skin and soft tissues 12 | 17,230
Urinary Tract 12 | 16,678

Target Family

Non-IDG 7 | 12,091
Enzyme 4 | 4,145
Transcription Factor 2 | 1,400

GWAS Trait

Body mass index (adult) 13 | 13
Obesity-related traits 569 | 569
Schizophrenia 533 | 533
Breast cancer 492 | 492
Body mass index 379 | 379
Height 369 | 369
Coronary artery disease 367 | 367
Blood protein levels 351 | 351
Post bronchodilator FEV1-FVC r... 308 | 308
Mean corpuscular volume 283 | 283
Platelet count 275 | 275
Intelligence (multi-trait anal... 267 | 267
Mean platelet volume 253 | 253
IgG glycosylation 250 | 250
Mean corpuscular hemoglobin 238 | 238
Inflammatory bowel disease 235 | 235
Plateletcrit 227 | 227
Crohn's disease 215 | 215
Type 2 diabetes 210 | 210
Red blood cell count 191 | 191
Monocyte count 183 | 183
Red cell distribution width 182 | 182
Eosinophil counts 180 | 180
Neuroticism 180 | 180
Platelet distribution width 174 | 174
Monocyte percentage of white c... 173 | 173
Post bronchodilator FEV1 173 | 173
Sum eosinophil basophil counts 173 | 173
White blood cell count 172 | 172
3-hydroxy-1-methylpropylmercap... 166 | 166
Eosinophil percentage of granu... 163 | 163
Eosinophil percentage of white... 163 | 163
Reticulocyte fraction of red c... 163 | 163
Ulcerative colitis 163 | 163
Granulocyte percentage of myel... 162 | 162
Itch intensity from mosquito b... 162 | 162
Systemic lupus erythematosus 159 | 159
High light scatter reticulocyt... 158 | 158
Lymphocyte counts 158 | 158
Reticulocyte count 158 | 158
Blood metabolite levels 157 | 157
Neutrophil count 154 | 154
High light scatter reticulocyt... 153 | 153
Neutrophil percentage of granu... 153 | 153
3-hydroxypropylmercapturic aci... 150 | 150
Tonsillectomy 149 | 149
Diastolic blood pressure 144 | 144
Sum basophil neutrophil counts 140 | 140
Autism spectrum disorder or sc... 134 | 134
Myeloid white cell count 133 | 133
Granulocyte count 132 | 132
Sum neutrophil eosinophil coun... 129 | 129
Colorectal cancer 126 | 126
Alzheimer disease and age of o... 124 | 124
Multiple sclerosis 124 | 124
Cholesterol, total 123 | 123
Night sleep phenotypes 123 | 123
Lung cancer 122 | 122
Lymphocyte percentage of white... 122 | 122
Menarche (age at onset) 122 | 122
Neutrophil percentage of white... 121 | 121
Rheumatoid arthritis 121 | 121
Systolic blood pressure 120 | 120
Immature fraction of reticuloc... 118 | 118
Diisocyanate-induced asthma 116 | 116
HDL cholesterol 116 | 116
Allergic disease (asthma, hay ... 115 | 115
Educational attainment (years ... 114 | 114
Hematocrit 113 | 113
Hemoglobin concentration 112 | 112
LDL cholesterol 110 | 110
QT interval 110 | 110
Waist circumference adjusted f... 110 | 110
Mosquito bite size 107 | 107
Asthma 106 | 106
Lobe attachment (rater-scored ... 103 | 103
Peripheral arterial disease (t... 101 | 101
Pulse pressure 97 | 97
Bipolar disorder 94 | 94
Major depressive disorder 94 | 94
Prostate cancer 92 | 92
Parkinson's disease 90 | 90
Hip circumference adjusted for... 89 | 89
Metabolite levels 87 | 87
Triglycerides 87 | 87
Colonoscopy-negative controls ... 85 | 85
Mean corpuscular hemoglobin co... 85 | 85
Itch intensity from mosquito b... 84 | 84
Bipolar disorder and schizophr... 83 | 83
Resting heart rate 82 | 82
Macrophage inflammatory protei... 81 | 81
Migraine 81 | 81
Waist-to-hip ratio adjusted fo... 81 | 81
PR interval in Tripanosoma cru... 80 | 80
Cognitive performance 79 | 79
Glomerular filtration rate (cr... 78 | 78
Late-onset Alzheimer's disease 78 | 78
Waist circumference adjusted f... 75 | 75
Tuberculosis 73 | 73
Type 1 diabetes 73 | 73
Morning vs. evening chronotype 72 | 72

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Kelch-like protein 32 KLHL32 Tdark Non-IDG 0.18 0.58 64
Transmembrane protein 18 TMEM18 Tbio Non-IDG -1.42979 26.0 80
Microfibril-associated glycoprotein 3 MFAP3 Tdark Non-IDG 0.15 0.82 94
Brain-derived neurotrophic factor BDNF Tbio Non-IDG -4.00507 10701.6 723
Nuclear pore complex-interacting protein family member B9 NPIPB9 Tdark Non-IDG 0.00000 0
Adenylate cyclase type 3 ADCY3 Tbio Enzyme -2.31593 204.4 82
Protein monoglycylase TTLL8 TTLL8 Tdark Enzyme -0.12494 0.88 19
Polypeptide N-acetylgalactosaminyltransferase 10 GALNT10 Tbio Enzyme -0.88348 7.68 127
Alpha-ketoglutarate-dependent dioxygenase FTO FTO Tbio Enzyme -3.13021 1342.0 318
Integrator complex subunit 10 INTS10 Tdark Non-IDG -0.67290 3.96 116