Development Level

Tbio 255 | 11,445
Tdark 60 | 6,588
Tchem 37 | 1,598
Tclin 27 | 613

Collection

RFA-RM-18-021 14 | 328
Kinase: IDG Consortium (Target... 6 | 125
GPCR: IDG Consortium (Targets) 4 | 126
Ion Channel: IDG Consortium (T... 4 | 99

IMPC Phenotype

preweaning lethality, complete... 31 | 979
preweaning lethality, incomple... 15 | 499
abnormal behavior 11 | 298
decreased total body fat amoun... 9 | 207
abnormal bone structure 6 | 187
abnormal embryo size 6 | 220
abnormal retina morphology 5 | 71
decreased circulating HDL chol... 5 | 68
decreased circulating alkaline... 5 | 46
decreased circulating choleste... 5 | 93
decreased grip strength 5 | 116
decreased prepulse inhibition 5 | 82
embryonic lethality prior to t... 5 | 278
hyperactivity 5 | 148
increased lean body mass 5 | 172
increased mean corpuscular hem... 5 | 96
increased startle reflex 5 | 112
decreased body length 4 | 101
decreased bone mineral density 4 | 126
decreased circulating LDL chol... 4 | 38
decreased fasted circulating g... 4 | 65
enlarged heart 4 | 210
hypoactivity 4 | 132
impaired glucose tolerance 4 | 75
increased circulating alkaline... 4 | 122
prenatal lethality prior to he... 4 | 87
short tibia 4 | 97
abnormal eye morphology 3 | 68
abnormal gait 3 | 69
abnormal heart morphology 3 | 162
abnormal locomotor behavior 3 | 24
abnormal sleep behavior 3 | 70
decreased body weight 3 | 161
decreased bone mineral content 3 | 151
decreased caudal vertebrae num... 3 | 53
decreased circulating insulin ... 3 | 76
decreased food intake 3 | 13
decreased lean body mass 3 | 135
edema 3 | 59
enlarged lymph nodes 3 | 37
improved glucose tolerance 3 | 79
increased bone mineral content 3 | 108
increased circulating chloride... 3 | 41
increased leukocyte cell numbe... 3 | 47
increased lymphocyte cell numb... 3 | 32
increased red blood cell distr... 3 | 34
increased total body fat amoun... 3 | 134
increased vertical activity 3 | 24
pallor 3 | 34
small thymus 3 | 16
tremors 3 | 39
abnormal coat-hair pigmentatio... 2 | 64
abnormal epididymis morphology 2 | 42
abnormal placenta size 2 | 20
abnormal rib morphology 2 | 10
abnormal seminal vesicle morph... 2 | 114
abnormal skin morphology 2 | 50
abnormal stomach morphology 2 | 10
anophthalmia 2 | 33
cataract 2 | 92
decreased circulating alanine ... 2 | 47
decreased circulating phosphat... 2 | 27
decreased circulating total pr... 2 | 49
decreased erythrocyte cell num... 2 | 62
decreased heart weight 2 | 27
decreased lymphocyte cell numb... 2 | 83
decreased mean corpuscular hem... 2 | 31
decreased mean corpuscular vol... 2 | 79
decreased pulmonary respirator... 2 | 5
decreased vertical activity 2 | 208
embryonic lethality prior to o... 2 | 239
enlarged stomach 2 | 2
increased blood urea nitrogen ... 2 | 48
increased body weight 2 | 25
increased bone mineral density 2 | 72
increased circulating amylase ... 2 | 25
increased circulating triglyce... 2 | 42
increased exploration in new e... 2 | 8
increased fasted circulating g... 2 | 76
increased hemoglobin content 2 | 45
limb grasping 2 | 41
thrombocytopenia 2 | 56
abnormal heart left ventricle ... 1 | 16
absent vibrissae 1 | 12
convulsive seizures 1 | 13
decreased T cell number 1 | 15
decreased circulating bilirubi... 1 | 19
decreased circulating calcium ... 1 | 36
decreased circulating iron lev... 1 | 32
decreased circulating potassiu... 1 | 20
decreased eosinophil cell numb... 1 | 24
decreased fluid intake 1 | 3
decreased neutrophil cell numb... 1 | 42
enlarged spleen 1 | 41
increased circulating aspartat... 1 | 15
increased circulating choleste... 1 | 66
increased circulating iron lev... 1 | 30
increased circulating potassiu... 1 | 29
increased mean corpuscular vol... 1 | 92
thrombocytosis 1 | 27

Disease

Carcinoma 294 | 11,493
ovarian cancer 197 | 8,520
osteosarcoma 183 | 7,950
medulloblastoma, large-cell 175 | 6,241
glioblastoma 164 | 5,792
atypical teratoid / rhabdoid tumor 154 | 5,112
psoriasis 148 | 6,694
ependymoma 146 | 4,679
lung cancer 117 | 4,740
adult high grade glioma 113 | 3,801
Kidney cancer 112 | 2,613
group 3 medulloblastoma 109 | 4,104
Breast cancer 102 | 3,578
Astrocytoma, Pilocytic 99 | 3,081
primitive neuroectodermal tumor 97 | 3,035
subependymal giant cell astrocytoma 87 | 2,287
oligodendroglioma 83 | 2,850
Acquired metabolic disease 81 | 336
lung carcinoma 80 | 2,843
intraductal papillary-mucinous carcinoma (IPMC) 79 | 2,989
malignant mesothelioma 79 | 3,232
intraductal papillary-mucinous neoplasm (IPMN) 78 | 3,291
intraductal papillary-mucinous adenoma (IPMA) 74 | 2,955
astrocytic glioma 73 | 2,597
invasive ductal carcinoma 68 | 2,951
Pick disease 67 | 1,894
pituitary cancer 66 | 1,972
lung adenocarcinoma 65 | 2,716
Cancer 60 | 2,499
Schizophrenia 60 | 1,160
group 4 medulloblastoma 55 | 1,855
non-small cell lung cancer 55 | 2,890
pancreatic cancer 53 | 2,398
Obesity 49 | 678
pancreatic ductal adenocarcinoma liver metastasis 48 | 1,962
tuberculosis 48 | 2,010
interstitial cystitis 46 | 2,312
diabetes mellitus 45 | 1,728
ductal carcinoma in situ 45 | 1,745
Bipolar Disorder 43 | 666
cystic fibrosis 40 | 1,696
Liver cancer 38 | 604
Melanoma 37 | 711
colon cancer 36 | 1,478
Intellectual disability 35 | 1,016
Rheumatoid arthritis 35 | 1,191
breast carcinoma 35 | 1,638
ulcerative colitis 35 | 1,819
Alzheimer's disease 32 | 658
astrocytoma 32 | 1,146
pediatric high grade glioma 32 | 1,064
Epilepsy 31 | 792
Autosomal recessive predisposition 30 | 1,442
Type 2 diabetes mellitus 30 | 272
spina bifida 30 | 1,074
Autistic Disorder 28 | 364
Skin cancer 28 | 469
adrenocortical carcinoma 28 | 1,428
juvenile dermatomyositis 26 | 1,187
Dull intelligence 25 | 645
Low intelligence 25 | 645
Mental Retardation 25 | 645
Mental deficiency 25 | 645
Poor school performance 25 | 645
primary pancreatic ductal adenocarcinoma 25 | 1,109
acute quadriplegic myopathy 24 | 1,158
medulloblastoma 24 | 720
Parkinson's disease 21 | 392
dermatomyositis 21 | 966
Depressive disorder 20 | 409
Diabetes Mellitus, Type 2 20 | 142
aldosterone-producing adenoma 20 | 665
progressive supranuclear palsy 20 | 676
Liver Cirrhosis, Experimental 19 | 769
Mental Depression 19 | 333
Multiple myeloma 19 | 1,332
gastric carcinoma 19 | 807
non primary Sjogren syndrome sicca 19 | 891
Endometrial cancer 18 | 311
Kidney disease 18 | 430
esophageal adenocarcinoma 18 | 737
Alcoholic Intoxication, Chronic 17 | 289
Diabetes Mellitus, Non-Insulin-Dependent 17 | 145
Major Depressive Disorder 17 | 301
Seizures 17 | 596
Multiple Sclerosis 16 | 540
Prostatic Neoplasms 16 | 495
cutaneous lupus erythematosus 16 | 1,057
nasopharyngeal carcinoma 16 | 1,058
Muscle hypotonia 15 | 571
Unipolar Depression 15 | 250
Waldenstrons macroglobulinemia 15 | 765
Amyotrophic lateral sclerosis 14 | 451
active ulcerative colitis 14 | 764
acute myeloid leukemia 14 | 783
non-small cell lung carcinoma 14 | 317
Down syndrome 13 | 499
Mood Disorders 13 | 184
fibroadenoma 13 | 559
primary Sjogren syndrome 13 | 735

Tissue

Endocrine System 365 | 18,159
Female tissues 359 | 17,400
Nervous System 357 | 16,725
Digestive Tract 355 | 17,369
Skin and soft tissues 355 | 17,230
Male tissues 354 | 17,142
Urinary Tract 350 | 16,678
Liver and Pancreas 344 | 16,750
Respiratory system 341 | 16,393
Blood and immune system 339 | 16,909
Cardiovascular System 322 | 15,192

Target Family

Non-IDG 195 | 12,091
Enzyme 75 | 4,145
Transcription Factor 37 | 1,400
Kinase 26 | 634
Ion Channel 15 | 344
Epigenetic 10 | 242
GPCR 8 | 408
Transporter 6 | 473
oGPCR 4 | 421
Nuclear Receptor 3 | 48

GWAS Trait

Body mass index 379 | 379
Obesity-related traits 569 | 569
Schizophrenia 533 | 533
Breast cancer 492 | 492
Height 369 | 369
Coronary artery disease 367 | 367
Blood protein levels 351 | 351
Post bronchodilator FEV1-FVC r... 308 | 308
Mean corpuscular volume 283 | 283
Platelet count 275 | 275
Intelligence (multi-trait anal... 267 | 267
Mean platelet volume 253 | 253
IgG glycosylation 250 | 250
Mean corpuscular hemoglobin 238 | 238
Inflammatory bowel disease 235 | 235
Plateletcrit 227 | 227
Crohn's disease 215 | 215
Type 2 diabetes 210 | 210
Red blood cell count 191 | 191
Monocyte count 183 | 183
Red cell distribution width 182 | 182
Eosinophil counts 180 | 180
Neuroticism 180 | 180
Platelet distribution width 174 | 174
Monocyte percentage of white c... 173 | 173
Post bronchodilator FEV1 173 | 173
Sum eosinophil basophil counts 173 | 173
White blood cell count 172 | 172
3-hydroxy-1-methylpropylmercap... 166 | 166
Eosinophil percentage of granu... 163 | 163
Eosinophil percentage of white... 163 | 163
Reticulocyte fraction of red c... 163 | 163
Ulcerative colitis 163 | 163
Granulocyte percentage of myel... 162 | 162
Itch intensity from mosquito b... 162 | 162
Systemic lupus erythematosus 159 | 159
High light scatter reticulocyt... 158 | 158
Lymphocyte counts 158 | 158
Reticulocyte count 158 | 158
Blood metabolite levels 157 | 157
Neutrophil count 154 | 154
High light scatter reticulocyt... 153 | 153
Neutrophil percentage of granu... 153 | 153
3-hydroxypropylmercapturic aci... 150 | 150
Tonsillectomy 149 | 149
Diastolic blood pressure 144 | 144
Sum basophil neutrophil counts 140 | 140
Autism spectrum disorder or sc... 134 | 134
Myeloid white cell count 133 | 133
Granulocyte count 132 | 132
Sum neutrophil eosinophil coun... 129 | 129
Colorectal cancer 126 | 126
Alzheimer disease and age of o... 124 | 124
Multiple sclerosis 124 | 124
Cholesterol, total 123 | 123
Night sleep phenotypes 123 | 123
Lung cancer 122 | 122
Lymphocyte percentage of white... 122 | 122
Menarche (age at onset) 122 | 122
Neutrophil percentage of white... 121 | 121
Rheumatoid arthritis 121 | 121
Systolic blood pressure 120 | 120
Immature fraction of reticuloc... 118 | 118
Diisocyanate-induced asthma 116 | 116
HDL cholesterol 116 | 116
Allergic disease (asthma, hay ... 115 | 115
Educational attainment (years ... 114 | 114
Hematocrit 113 | 113
Hemoglobin concentration 112 | 112
LDL cholesterol 110 | 110
QT interval 110 | 110
Waist circumference adjusted f... 110 | 110
Mosquito bite size 107 | 107
Asthma 106 | 106
Lobe attachment (rater-scored ... 103 | 103
Peripheral arterial disease (t... 101 | 101
Pulse pressure 97 | 97
Bipolar disorder 94 | 94
Major depressive disorder 94 | 94
Prostate cancer 92 | 92
Parkinson's disease 90 | 90
Hip circumference adjusted for... 89 | 89
Metabolite levels 87 | 87
Triglycerides 87 | 87
Colonoscopy-negative controls ... 85 | 85
Mean corpuscular hemoglobin co... 85 | 85
Itch intensity from mosquito b... 84 | 84
Bipolar disorder and schizophr... 83 | 83
Resting heart rate 82 | 82
Macrophage inflammatory protei... 81 | 81
Migraine 81 | 81
Waist-to-hip ratio adjusted fo... 81 | 81
PR interval in Tripanosoma cru... 80 | 80
Cognitive performance 79 | 79
Glomerular filtration rate (cr... 78 | 78
Late-onset Alzheimer's disease 78 | 78
Waist circumference adjusted f... 75 | 75
Tuberculosis 73 | 73
Type 1 diabetes 73 | 73
Morning vs. evening chronotype 72 | 72

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
CAP-Gly domain-containing linker protein 1 CLIP1 Tbio Non-IDG -2.54943 343.7 221
Zinc finger SWIM domain-containing protein 6 ZSWIM6 Tbio Non-IDG -1.22042 16.2 67
Importin-9 IPO9 Tbio Non-IDG -1.14983 12.2 108
Potassium voltage-gated channel subfamily E member 4 KCNE4 Tbio Ion Channel -1.17671 15.9 99
Putative postmeiotic segregation increased 2-like protein 11 PMS2P11 Tdark Enzyme -2.19299 339.5 0
Ataxin-2-like protein ATXN2L Tbio Non-IDG -1.58925 37.9 93
Proteasome activator complex subunit 4 PSME4 Tdark Non-IDG -1.60128 39.3 43
RNA binding protein fox-1 homolog 3 RBFOX3 Tbio Non-IDG -3.23341 1462.9 208
DBF4-type zinc finger-containing protein 2 ZDBF2 Tbio Non-IDG -0.82246 7.11 9
Dual specificity protein phosphatase 9 DUSP9 Tbio Enzyme -1.15238 17.2 202