Development Level

Tbio 31 | 11,445
Tchem 11 | 1,598
Tdark 8 | 6,588
Tclin 3 | 613

Collection

Ion Channel: IDG Consortium (T... 1 | 99

IMPC Phenotype

preweaning lethality, complete... 3 | 979
abnormal retinal vasculature m... 2 | 27
abnormal seminal vesicle morph... 2 | 114
abnormal bone structure 1 | 187
abnormal embryo size 1 | 220
abnormal heart left ventricle ... 1 | 16
abnormal retina morphology 1 | 71
abnormal retinal blood vessel ... 1 | 26
abnormal testis morphology 1 | 43
abnormal tooth morphology 1 | 24
decreased circulating glucose ... 1 | 126
decreased circulating serum al... 1 | 82
decreased circulating sodium l... 1 | 22
decreased erythrocyte cell num... 1 | 62
decreased fasted circulating g... 1 | 65
decreased vertical activity 1 | 208
embryonic growth retardation 1 | 106
embryonic lethality prior to t... 1 | 278
hypoactivity 1 | 132
improved glucose tolerance 1 | 79
increased cardiac muscle contr... 1 | 8
increased caudal vertebrae num... 1 | 7
increased circulating LDL chol... 1 | 13
increased circulating alkaline... 1 | 122
increased circulating bilirubi... 1 | 16
increased circulating choleste... 1 | 66
increased circulating free fat... 1 | 20
increased circulating triglyce... 1 | 42
increased heart rate 1 | 23
increased mean corpuscular hem... 1 | 36
increased mean corpuscular vol... 1 | 92
increased total body fat amoun... 1 | 134
persistence of hyaloid vascula... 1 | 33
prolonged ST segment 1 | 36
small testis 1 | 58

Disease

Carcinoma 37 | 11,493
psoriasis 28 | 6,694
osteosarcoma 22 | 7,950
ovarian cancer 20 | 8,520
medulloblastoma, large-cell 16 | 6,241
pancreatic ductal adenocarcinoma liver metastasis 15 | 1,962
lung carcinoma 14 | 2,843
non-small cell lung cancer 13 | 2,890
interstitial cystitis 12 | 2,312
Autosomal recessive predisposition 11 | 1,442
cystic fibrosis 11 | 1,696
ependymoma 11 | 4,679
lung cancer 11 | 4,740
malignant mesothelioma 11 | 3,232
glioblastoma 10 | 5,792
Alzheimer's disease 9 | 658
Cancer 9 | 2,499
intraductal papillary-mucinous adenoma (IPMA) 9 | 2,955
lung adenocarcinoma 9 | 2,716
oligodendroglioma 9 | 2,850
Kidney disease 8 | 430
Schizophrenia 8 | 1,160
adult high grade glioma 8 | 3,801
intraductal papillary-mucinous neoplasm (IPMN) 8 | 3,291
nephrosclerosis 8 | 333
pancreatic cancer 8 | 2,398
Astrocytoma, Pilocytic 7 | 3,081
Breast cancer 7 | 3,578
Liver Cirrhosis, Experimental 7 | 769
Obesity 7 | 678
Rheumatoid arthritis 7 | 1,191
active ulcerative colitis 7 | 764
adrenocortical carcinoma 7 | 1,428
astrocytic glioma 7 | 2,597
atypical teratoid / rhabdoid tumor 7 | 5,112
colon cancer 7 | 1,478
group 3 medulloblastoma 7 | 4,104
intraductal papillary-mucinous carcinoma (IPMC) 7 | 2,989
ulcerative colitis 7 | 1,819
Alcoholic Intoxication, Chronic 6 | 289
Atopic dermatitis 6 | 952
Bipolar Disorder 6 | 666
Coronary artery disease 6 | 268
Pick disease 6 | 1,894
aldosterone-producing adenoma 6 | 665
diabetes mellitus 6 | 1,728
ductal carcinoma in situ 6 | 1,745
nasopharyngeal carcinoma 6 | 1,058
spina bifida 6 | 1,074
Atherosclerosis 5 | 291
Gout 5 | 106
Lipid metabolism disorder 5 | 114
Prostatic Neoplasms 5 | 495
active Crohn's disease 5 | 922
invasive ductal carcinoma 5 | 2,951
pituitary cancer 5 | 1,972
subependymal giant cell astrocytoma 5 | 2,287
tuberculosis 5 | 2,010
Acquired metabolic disease 4 | 336
Cardiovascular system disease 4 | 246
Chemical and Drug Induced Liver Injury 4 | 195
Crohn's disease 4 | 321
Heart disease 4 | 306
Hepatomegaly 4 | 285
Hypertension 4 | 396
Hypertensive disease 4 | 292
Hyperuricemia 4 | 49
Kidney Failure 4 | 111
Major Depressive Disorder 4 | 301
Unipolar Depression 4 | 250
Vascular disease 4 | 319
acute quadriplegic myopathy 4 | 1,158
esophageal adenocarcinoma 4 | 737
gastric carcinoma 4 | 807
non primary Sjogren syndrome sicca 4 | 891
primitive neuroectodermal tumor 4 | 3,035
Adverse reaction to drug 3 | 61
Cholestasis 3 | 155
Dementia 3 | 175
Disease of metabolism 3 | 18
Epilepsy 3 | 792
Icterus 3 | 82
Kidney cancer 3 | 2,613
Liver cancer 3 | 604
Mammary Neoplasms 3 | 425
Myopathy 3 | 185
Osteoporosis 3 | 363
Renal Insufficiency 3 | 90
Seizures 3 | 596
Type 2 diabetes mellitus 3 | 272
Vomiting 3 | 116
astrocytoma 3 | 1,146
atypical teratoid/rhabdoid tumor 3 | 357
chronic rhinosinusitis 3 | 512
facioscapulohumeral dystrophy 3 | 288
head and neck cancer and chronic obstructive pulmonary disease 3 | 239
juvenile dermatomyositis 3 | 1,187
pancreatic carcinoma 3 | 562
pediatric high grade glioma 3 | 1,064
urothelial carcinoma 3 | 318

Tissue

Liver and Pancreas 51 | 16,750
Urinary Tract 51 | 16,678
Endocrine System 50 | 18,159
Male tissues 50 | 17,142
Digestive Tract 49 | 17,369
Female tissues 49 | 17,400
Skin and soft tissues 48 | 17,230
Blood and immune system 46 | 16,909
Nervous System 46 | 16,725
Respiratory system 45 | 16,393
Cardiovascular System 39 | 15,192

Target Family

Enzyme 22 | 4,145
Non-IDG 13 | 12,091
Transporter 13 | 473
Ion Channel 2 | 344
Epigenetic 1 | 242
Kinase 1 | 634
Transcription Factor 1 | 1,400

GWAS Trait

Blood metabolite ratios 53 | 53
Obesity-related traits 569 | 569
Schizophrenia 533 | 533
Breast cancer 492 | 492
Body mass index 379 | 379
Height 369 | 369
Coronary artery disease 367 | 367
Blood protein levels 351 | 351
Post bronchodilator FEV1-FVC r... 308 | 308
Mean corpuscular volume 283 | 283
Platelet count 275 | 275
Intelligence (multi-trait anal... 267 | 267
Mean platelet volume 253 | 253
IgG glycosylation 250 | 250
Mean corpuscular hemoglobin 238 | 238
Inflammatory bowel disease 235 | 235
Plateletcrit 227 | 227
Crohn's disease 215 | 215
Type 2 diabetes 210 | 210
Red blood cell count 191 | 191
Monocyte count 183 | 183
Red cell distribution width 182 | 182
Eosinophil counts 180 | 180
Neuroticism 180 | 180
Platelet distribution width 174 | 174
Monocyte percentage of white c... 173 | 173
Post bronchodilator FEV1 173 | 173
Sum eosinophil basophil counts 173 | 173
White blood cell count 172 | 172
3-hydroxy-1-methylpropylmercap... 166 | 166
Eosinophil percentage of granu... 163 | 163
Eosinophil percentage of white... 163 | 163
Reticulocyte fraction of red c... 163 | 163
Ulcerative colitis 163 | 163
Granulocyte percentage of myel... 162 | 162
Itch intensity from mosquito b... 162 | 162
Systemic lupus erythematosus 159 | 159
High light scatter reticulocyt... 158 | 158
Lymphocyte counts 158 | 158
Reticulocyte count 158 | 158
Blood metabolite levels 157 | 157
Neutrophil count 154 | 154
High light scatter reticulocyt... 153 | 153
Neutrophil percentage of granu... 153 | 153
3-hydroxypropylmercapturic aci... 150 | 150
Tonsillectomy 149 | 149
Diastolic blood pressure 144 | 144
Sum basophil neutrophil counts 140 | 140
Autism spectrum disorder or sc... 134 | 134
Myeloid white cell count 133 | 133
Granulocyte count 132 | 132
Sum neutrophil eosinophil coun... 129 | 129
Colorectal cancer 126 | 126
Alzheimer disease and age of o... 124 | 124
Multiple sclerosis 124 | 124
Cholesterol, total 123 | 123
Night sleep phenotypes 123 | 123
Lung cancer 122 | 122
Lymphocyte percentage of white... 122 | 122
Menarche (age at onset) 122 | 122
Neutrophil percentage of white... 121 | 121
Rheumatoid arthritis 121 | 121
Systolic blood pressure 120 | 120
Immature fraction of reticuloc... 118 | 118
Diisocyanate-induced asthma 116 | 116
HDL cholesterol 116 | 116
Allergic disease (asthma, hay ... 115 | 115
Educational attainment (years ... 114 | 114
Hematocrit 113 | 113
Hemoglobin concentration 112 | 112
LDL cholesterol 110 | 110
QT interval 110 | 110
Waist circumference adjusted f... 110 | 110
Mosquito bite size 107 | 107
Asthma 106 | 106
Lobe attachment (rater-scored ... 103 | 103
Peripheral arterial disease (t... 101 | 101
Pulse pressure 97 | 97
Bipolar disorder 94 | 94
Major depressive disorder 94 | 94
Prostate cancer 92 | 92
Parkinson's disease 90 | 90
Hip circumference adjusted for... 89 | 89
Metabolite levels 87 | 87
Triglycerides 87 | 87
Colonoscopy-negative controls ... 85 | 85
Mean corpuscular hemoglobin co... 85 | 85
Itch intensity from mosquito b... 84 | 84
Bipolar disorder and schizophr... 83 | 83
Resting heart rate 82 | 82
Macrophage inflammatory protei... 81 | 81
Migraine 81 | 81
Waist-to-hip ratio adjusted fo... 81 | 81
PR interval in Tripanosoma cru... 80 | 80
Cognitive performance 79 | 79
Glomerular filtration rate (cr... 78 | 78
Late-onset Alzheimer's disease 78 | 78
Waist circumference adjusted f... 75 | 75
Tuberculosis 73 | 73
Type 1 diabetes 73 | 73
Morning vs. evening chronotype 72 | 72

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
HEAT repeat-containing protein 4 HEATR4 Tdark Non-IDG 0.90 0.10 40
Nesprin-2 SYNE2 Tbio Non-IDG -2.62747 380.6 39
Sodium-dependent phosphate transport protein 1 SLC17A1 Tbio Transporter -1.73498 53.1 39
Acyl-coenzyme A thioesterase 1 ACOT1 Tdark Enzyme -2.14311 129.6 43
N-acetyltransferase 8 NAT8 Tbio Enzyme -1.74418 54.5 143
Histo-blood group ABO system transferase ABO Tbio Enzyme 0.00000 0
Hydroxyacid-oxoacid transhydrogenase, mitochondrial ADHFE1 Tbio Enzyme -1.36842 25.4 83
MEF2-activating motif and SAP domain-containing transcriptional regulator MAMSTR Tbio Non-IDG -0.90607 7.14 75
PH and SEC7 domain-containing protein 3 PSD3 Tbio Non-IDG -1.24070 17.4 133
Elongation of very long chain fatty acids protein 2 ELOVL2 Tbio Non-IDG -1.99271 91.8 122