Development Level

Tbio 58 | 10,625
Tchem 24 | 1,890
Tdark 13 | 7,003
Tclin 8 | 602

IMPC Term

preweaning lethality, complete... 4 | 633
abnormal lens morphology 2 | 73
abnormal behavior 1 | 226
abnormal cranium morphology 1 | 32
abnormal embryo size 1 | 112
abnormal eye morphology 1 | 38
abnormal eye size 1 | 11
abnormal retina morphology 1 | 100
abnormal retinal vasculature m... 1 | 15
abnormal seminal vesicle morph... 1 | 47
abnormal skin appearance 1 | 8
abnormal testis morphology 1 | 30
anophthalmia 1 | 20
craniofacial phenotype 1 | 9
decreased Ly6C low monocyte nu... 1 | 23
decreased body weight 1 | 174
decreased bone mineral content 1 | 157
decreased circulating HDL chol... 1 | 77
decreased circulating fructosa... 1 | 31
decreased circulating glucose ... 1 | 121
decreased circulating potassiu... 1 | 17
decreased circulating serum al... 1 | 79
decreased circulating thyroxin... 1 | 5
decreased hemoglobin content 1 | 53
decreased mature B cell number 1 | 25
decreased mean corpuscular hem... 1 | 34
decreased pulmonary respirator... 1 | 4
herniated abdominal wall 1 | 4
hydrops fetalis 1 | 22
hyperactivity 1 | 108
hypoactivity 1 | 89
improved glucose tolerance 1 | 56
increased circulating alanine ... 1 | 11
increased circulating bilirubi... 1 | 16
increased circulating insulin ... 1 | 2
increased circulating sodium l... 1 | 71
increased exploration in new e... 1 | 56
increased fasted circulating g... 1 | 68
increased grip strength 1 | 83
increased heart rate variabili... 1 | 4
increased mean corpuscular vol... 1 | 91
increased red blood cell distr... 1 | 21
increased rib number 1 | 41
increased startle reflex 1 | 38
increased transitional stage T... 1 | 1
microphthalmia 1 | 15
pale yolk sac 1 | 12
persistence of hyaloid vascula... 1 | 22
prenatal lethality prior to he... 1 | 64
preweaning lethality, incomple... 1 | 260
small adrenal glands 1 | 15
small seminal vesicle 1 | 6
small testis 1 | 37
straub tail 1 | 26
thrombocytopenia 1 | 46

Disease

osteosarcoma 45 | 7,933
ovarian cancer 38 | 8,484
psoriasis 37 | 6,685
lung cancer 28 | 4,466
medulloblastoma, large-cell 28 | 6,234
pancreatic ductal adenocarcinoma liver metastasis 25 | 1,795
Cancer 21 | 2,346
malignant mesothelioma 21 | 3,162
glioblastoma 19 | 5,572
atypical teratoid / rhabdoid tumor 18 | 4,369
lung carcinoma 17 | 2,844
diabetes mellitus 16 | 1,663
intraductal papillary-mucinous neoplasm (IPMN) 16 | 3,289
intraductal papillary-mucinous adenoma (IPMA) 15 | 2,956
primitive neuroectodermal tumor 15 | 3,031
Obesity 14 | 616
ependymoma 14 | 2,514
group 3 medulloblastoma 14 | 2,254
non-small cell lung cancer 14 | 2,798
oligodendroglioma 14 | 2,849
Breast cancer 13 | 3,094
interstitial cystitis 13 | 2,299
lung adenocarcinoma 13 | 2,713
pancreatic cancer 13 | 2,300
colon cancer 12 | 1,475
cystic fibrosis 12 | 1,665
intraductal papillary-mucinous carcinoma (IPMC) 12 | 2,988
pediatric high grade glioma 12 | 2,712
pilocytic astrocytoma 11 | 3,086
tuberculosis 11 | 1,557
ulcerative colitis 11 | 2,087
Atherosclerosis 10 | 275
Carcinoma 10 | 2,147
Kidney disease 10 | 396
Metabolic syndrome X 10 | 155
astrocytic glioma 10 | 2,241
Hypertension 9 | 287
Pick disease 9 | 1,893
active Crohn's disease 9 | 918
Rheumatoid Arthritis 8 | 1,160
Vascular disease 8 | 281
astrocytoma 8 | 1,493
atypical teratoid/rhabdoid tumor 8 | 1,095
group 4 medulloblastoma 8 | 1,875
invasive ductal carcinoma 8 | 2,950
nephrosclerosis 8 | 329
posterior fossa group B ependymoma 8 | 1,530
Cardiovascular system disease 7 | 194
Coronary artery disease 7 | 240
active ulcerative colitis 7 | 477
ductal carcinoma in situ 7 | 1,745
sonic hedgehog group medulloblastoma 7 | 1,482
Asthma 6 | 349
Bilirubin metabolic disorder 6 | 39
Heart disease 6 | 279
Peripheral Neuropathy 6 | 303
Peripheral vascular disease 6 | 90
Prostatic Neoplasms 6 | 471
adrenocortical carcinoma 6 | 1,427
adult high grade glioma 6 | 2,148
mucosa-associated lymphoid tissue lymphoma 6 | 480
subependymal giant cell astrocytoma 6 | 2,287
Alzheimer's disease 5 | 644
Anemia 5 | 252
Atopic dermatitis 5 | 944
Cholestasis 5 | 93
Chronic Kidney Diseases 5 | 22
Crohn's disease 5 | 304
Dementia 5 | 129
Endometriosis 5 | 535
IGA Glomerulonephritis 5 | 454
Lipid metabolism disorder 5 | 102
Multiple myeloma 5 | 1,327
Systemic primary carnitine deficiency disease 5 | 16
breast carcinoma 5 | 1,614
chronic rhinosinusitis 5 | 512
medulloblastoma 5 | 1,524
nasopharyngeal carcinoma 5 | 1,056
Acquired metabolic disease 4 | 267
Adverse reaction to drug 4 | 54
Animal Mammary Neoplasms 4 | 136
Cerebrovascular disease 4 | 231
Colorectal Neoplasms 4 | 217
Down syndrome 4 | 548
Epilepsy 4 | 346
Gout 4 | 93
Hypertensive disease 4 | 193
Intellectual disability 4 | 573
Liver disease 4 | 219
Microcephaly 4 | 149
Neurodegenerative disease 4 | 383
Waldenstrons macroglobulinemia 4 | 765
acute myeloid leukemia 4 | 780
aldosterone-producing adenoma 4 | 664
facioscapulohumeral dystrophy 4 | 286
gastric carcinoma 4 | 832
non primary Sjogren syndrome sicca 4 | 840
pancreatic carcinoma 4 | 567
posterior fossa group A ependymoma 4 | 1,511
progressive supranuclear palsy 4 | 674

Tissue

Liver and Pancreas 102 | 18,136
Blood and immune system 101 | 17,995
Digestive Tract 101 | 18,473
Male tissues 101 | 17,969
Female tissues 100 | 18,647
Nervous System 100 | 18,561
Urinary Tract 100 | 18,444
Cardiovascular System 99 | 17,958
Endocrine System 99 | 18,512
Skin and soft tissues 98 | 18,115
Respiratory system 97 | 17,484

Target Family

Enzyme 53 | 4,146
Non-IDG 24 | 11,971
Transporter 19 | 473
Transcription Factor 4 | 1,400
Epigenetic 1 | 242
GPCR 1 | 406
Ion Channel 1 | 341

GWAS Trait

Blood metabolite levels 103 | 103
Obesity-related traits 380 | 380
Schizophrenia 334 | 334
Height 250 | 250
Post bronchodilator FEV1/FVC r... 192 | 192
Body mass index 180 | 180
IgG glycosylation 162 | 162
Inflammatory bowel disease 117 | 117
Post bronchodilator FEV1 112 | 112
Crohn's disease 110 | 110
Type 2 diabetes 94 | 94
3-hydroxy-1-methylpropylmercap... 93 | 93
3-hydroxypropylmercapturic aci... 92 | 92
Ulcerative colitis 89 | 89
Platelet count 79 | 79
Systemic lupus erythematosus 78 | 78
HDL cholesterol 76 | 76
Rheumatoid arthritis 74 | 74
Cholesterol, total 73 | 73
Menarche (age at onset) 73 | 73
Diisocyanate-induced asthma 72 | 72
Multiple sclerosis 68 | 68
LDL cholesterol 67 | 67
QT interval 58 | 58
Metabolite levels 55 | 55
Atopic dermatitis 54 | 54
Bipolar disorder and schizophr... 54 | 54
Breast cancer 54 | 54
Prostate cancer 54 | 54
Triglycerides 53 | 53
Bipolar disorder 52 | 52
HIV-1 control 50 | 50
Post bronchodilator FEV1/FVC r... 50 | 50
HIV-1 viral setpoint 49 | 49
Cognitive performance 48 | 48
Amyotrophic lateral sclerosis ... 46 | 46
Bone mineral density 46 | 46
Clozapine-induced agranulocyto... 46 | 46
Attention deficit hyperactivit... 44 | 44
Blood pressure 44 | 44
Coronary heart disease 43 | 43
Glomerular filtration rate (cr... 43 | 43
Parkinson's disease 43 | 43
Type 1 diabetes 42 | 42
PR interval in Tripanosoma cru... 40 | 40
Post bronchodilator FEV1 in CO... 39 | 39
Alzheimer's disease (cognitive... 38 | 38
Educational attainment 38 | 38
Pulmonary function 38 | 38
Diffuse large B cell lymphoma 37 | 37
Inflammatory skin disease 37 | 37
Beta-2 microglubulin plasma le... 36 | 36
Glucose homeostasis traits 36 | 36
Urate levels 36 | 36
Blood metabolite ratios 35 | 35
Psoriasis 35 | 35
Autism spectrum disorder, atte... 34 | 34
Migraine 33 | 33
Coronary artery disease 32 | 32
Metabolic traits 32 | 32
Waist-to-hip ratio adjusted fo... 32 | 32
Cognitive function 31 | 31
Colorectal cancer 31 | 31
Amyotrophic lateral sclerosis 30 | 30
Myopia (pathological) 30 | 30
Obesity 30 | 30
Response to amphetamines 30 | 30
Systolic blood pressure 30 | 30
Alzheimer's disease (late onse... 29 | 29
Celiac disease 29 | 29
Phospholipid levels (plasma) 29 | 29
Red blood cell traits 29 | 29
Advanced age-related macular d... 28 | 28
Dental caries 28 | 28
Fibrinogen levels 28 | 28
Parental extreme longevity (95... 28 | 28
Pulmonary function (interactio... 28 | 28
Asthma 27 | 27
Cognitive decline rate in late... 27 | 27
Glomerular filtration rate in ... 27 | 27
Longevity 27 | 27
Mean platelet volume 27 | 27
Chronic kidney disease 26 | 26
Diabetic kidney disease 26 | 26
Diastolic blood pressure 26 | 26
Coronary artery calcification 25 | 25
Metabolic syndrome 25 | 25
Pancreatic cancer 25 | 25
Protein quantitative trait loc... 25 | 25
Hypertension 24 | 24
Migraine - clinic-based 24 | 24
Parental longevity (combined p... 24 | 24
Primary biliary cirrhosis 24 | 24
Thiazide-induced adverse metab... 24 | 24
Menopause (age at onset) 23 | 23
Response to antipsychotic trea... 23 | 23
Age-related macular degenerati... 22 | 22
Immune response to smallpox va... 22 | 22
Mild influenza (H1N1) infectio... 22 | 22
Sudden cardiac arrest 22 | 22

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Plasma kallikrein KLKB1 Tclin Enzyme -2.88472 708.0 231
SH2B adapter protein 3 SH2B3 Tbio Non-IDG -2.46631 317.6 137
Hermansky-Pudlak syndrome 5 protein HPS5 Tbio Non-IDG -1.13658 13.9 71
Nuclear autoantigenic sperm protein NASP Tbio Non-IDG -1.72078 58.3 103
Monocarboxylate transporter 9 SLC16A9 Tbio Transporter -0.78270 6.92 47
Indoleamine 2,3-dioxygenase 2 IDO2 Tchem Enzyme -1.88853 82.2 208
Transmembrane protein 258 TMEM258 Tdark Non-IDG 0.12 1.54 5
Zinc finger CW-type PWWP domain protein 1 ZCWPW1 Tdark Epigenetic -0.53593 3.59 35
Solute carrier family 22 member 4 SLC22A4 Tchem Transporter -3.04092 1151.9 69
Medium-chain specific acyl-CoA dehydrogenase, mitochondrial ACADM Tbio Enzyme -2.58670 387.0 269