Development Level

Tbio 97 | 11,651
Tdark 25 | 6,593
Tchem 24 | 1,388
Tclin 11 | 612

Collection

Ion Channel: IDG Consortium (T... 1 | 99
RFA-RM-18-021 1 | 328

IMPC Phenotype

preweaning lethality, complete... 7 | 979
abnormal embryo size 5 | 220
abnormal seminal vesicle morph... 3 | 114
preweaning lethality, incomple... 3 | 499
abnormal heart morphology 2 | 162
abnormal locomotor behavior 2 | 24
abnormal retinal vasculature m... 2 | 27
decreased circulating HDL chol... 2 | 68
decreased lymphocyte cell numb... 2 | 83
edema 2 | 59
improved glucose tolerance 2 | 79
increased circulating sodium l... 2 | 71
male infertility 2 | 123
microphthalmia 2 | 26
persistence of hyaloid vascula... 2 | 33
abnormal behavior 1 | 298
abnormal craniofacial morpholo... 1 | 33
abnormal cranium morphology 1 | 36
abnormal embryo turning 1 | 31
abnormal eye morphology 1 | 68
abnormal heart left ventricle ... 1 | 16
abnormal lens morphology 1 | 81
abnormal retina morphology 1 | 71
abnormal retinal blood vessel ... 1 | 26
abnormal sensory capabilities-... 1 | 8
abnormal testis morphology 1 | 43
anophthalmia 1 | 33
decreased blood urea nitrogen ... 1 | 51
decreased body weight 1 | 161
decreased circulating bilirubi... 1 | 19
decreased circulating choleste... 1 | 93
decreased circulating fructosa... 1 | 30
decreased circulating glucose ... 1 | 126
decreased circulating iron lev... 1 | 32
decreased circulating lipase l... 1 | 3
decreased circulating potassiu... 1 | 20
decreased circulating serum al... 1 | 82
decreased circulating triglyce... 1 | 79
decreased erythrocyte cell num... 1 | 62
decreased fasted circulating g... 1 | 65
decreased grip strength 1 | 116
decreased hemoglobin content 1 | 68
decreased large unstained cell... 1 | 11
decreased pulmonary respirator... 1 | 5
decreased vertical activity 1 | 208
embryonic growth retardation 1 | 106
embryonic lethality prior to o... 1 | 239
embryonic lethality prior to t... 1 | 278
enlarged heart 1 | 210
enlarged seminal vesicle 1 | 10
female infertility 1 | 60
hydrometra 1 | 53
hyperactivity 1 | 148
hypoactivity 1 | 132
increased bone mineral content 1 | 108
increased bone mineral density 1 | 72
increased cardiac muscle contr... 1 | 8
increased circulating alanine ... 1 | 13
increased circulating bilirubi... 1 | 16
increased heart rate 1 | 23
increased leukocyte cell numbe... 1 | 47
increased mean corpuscular vol... 1 | 92
increased monocyte cell number 1 | 63
increased neutrophil cell numb... 1 | 46
pale yolk sac 1 | 25
pallor 1 | 34
prenatal lethality prior to he... 1 | 87
prolonged ST segment 1 | 36
short tibia 1 | 97
small adrenal glands 1 | 16
small seminal vesicle 1 | 10
small superior vagus ganglion 1 | 74
small testis 1 | 58
thrombocytopenia 1 | 56

Disease

Carcinoma 118 | 11,493
osteosarcoma 60 | 7,950
ovarian cancer 58 | 8,520
psoriasis 57 | 6,694
lung cancer 39 | 4,740
pancreatic ductal adenocarcinoma liver metastasis 39 | 1,962
medulloblastoma, large-cell 38 | 6,241
ependymoma 37 | 4,679
Autosomal recessive predisposition 31 | 1,442
Cancer 30 | 2,499
glioblastoma 30 | 5,792
malignant mesothelioma 29 | 3,232
atypical teratoid / rhabdoid tumor 28 | 5,112
group 3 medulloblastoma 26 | 4,104
lung carcinoma 25 | 2,843
non-small cell lung cancer 25 | 2,890
intraductal papillary-mucinous adenoma (IPMA) 23 | 2,955
pancreatic cancer 23 | 2,398
adult high grade glioma 22 | 3,801
intraductal papillary-mucinous neoplasm (IPMN) 22 | 3,291
diabetes mellitus 21 | 1,728
Breast cancer 20 | 3,578
oligodendroglioma 20 | 2,850
primitive neuroectodermal tumor 20 | 3,035
interstitial cystitis 19 | 2,312
Schizophrenia 18 | 1,160
cystic fibrosis 18 | 1,696
lung adenocarcinoma 18 | 2,716
Epilepsy 17 | 792
astrocytic glioma 17 | 2,597
colon cancer 17 | 1,478
intraductal papillary-mucinous carcinoma (IPMC) 17 | 2,989
tuberculosis 17 | 2,010
Astrocytoma, Pilocytic 16 | 3,081
active ulcerative colitis 16 | 764
Atherosclerosis 15 | 291
Hypertension 15 | 396
Kidney cancer 15 | 2,613
Obesity 15 | 678
ulcerative colitis 15 | 1,819
Coronary artery disease 14 | 268
Kidney disease 14 | 430
Prostatic Neoplasms 14 | 495
active Crohn's disease 14 | 922
nephrosclerosis 13 | 333
Anemia 12 | 365
Bilirubin metabolic disorder 12 | 41
Bipolar Disorder 12 | 666
Cardiovascular system disease 12 | 246
Intellectual disability 12 | 1,016
invasive ductal carcinoma 12 | 2,951
Chemical and Drug Induced Liver Injury 11 | 195
Hypertensive disease 11 | 292
Liver Cirrhosis, Experimental 11 | 769
Pick disease 11 | 1,894
Vascular disease 11 | 319
ductal carcinoma in situ 11 | 1,745
group 4 medulloblastoma 11 | 1,855
Major Depressive Disorder 10 | 301
Muscle hypotonia 10 | 571
Rheumatoid arthritis 10 | 1,191
pituitary cancer 10 | 1,972
spina bifida 10 | 1,074
subependymal giant cell astrocytoma 10 | 2,287
Alcoholic Intoxication, Chronic 9 | 289
Cognitive delay 9 | 608
Dull intelligence 9 | 645
Global developmental delay 9 | 608
Low intelligence 9 | 645
Mental Retardation 9 | 645
Mental and motor retardation 9 | 608
Mental deficiency 9 | 645
Metabolic syndrome X 9 | 52
Poor school performance 9 | 645
Seizures 9 | 596
Sickle Cell Anemia 9 | 53
Unipolar Depression 9 | 250
adrenocortical carcinoma 9 | 1,428
breast carcinoma 9 | 1,638
Alzheimer's disease 8 | 658
Atopic dermatitis 8 | 952
Attention deficit hyperactivity disorder 8 | 278
Cholestasis 8 | 155
Crohn's disease 8 | 321
Depressive disorder 8 | 409
Hepatomegaly 8 | 285
Lipid metabolism disorder 8 | 114
Liver cancer 8 | 604
Peripheral vascular disease 8 | 87
astrocytoma 8 | 1,146
nasopharyngeal carcinoma 8 | 1,058
Asthma 7 | 385
Cerebrovascular disease 7 | 238
Failure to gain weight 7 | 365
Pediatric failure to thrive 7 | 365
Type 2 diabetes mellitus 7 | 272
cutaneous lupus erythematosus 7 | 1,057
mucosa-associated lymphoid tissue lymphoma 7 | 484
non primary Sjogren syndrome sicca 7 | 891
progressive supranuclear palsy 7 | 676

Tissue

Liver and Pancreas 152 | 16,750
Digestive Tract 150 | 17,369
Urinary Tract 150 | 16,678
Skin and soft tissues 148 | 17,230
Endocrine System 146 | 18,159
Female tissues 146 | 17,400
Male tissues 145 | 17,142
Blood and immune system 139 | 16,909
Nervous System 139 | 16,725
Respiratory system 134 | 16,393
Cardiovascular System 117 | 15,192

Target Family

Enzyme 78 | 4,145
Non-IDG 44 | 12,091
Transporter 21 | 473
Transcription Factor 7 | 1,400
Ion Channel 3 | 344
Epigenetic 1 | 242
GPCR 1 | 408
Kinase 1 | 634
Nuclear Receptor 1 | 48

GWAS Trait

Blood metabolite levels 157 | 157
Obesity-related traits 569 | 569
Schizophrenia 533 | 533
Breast cancer 492 | 492
Body mass index 379 | 379
Height 369 | 369
Coronary artery disease 367 | 367
Blood protein levels 351 | 351
Post bronchodilator FEV1-FVC r... 308 | 308
Mean corpuscular volume 283 | 283
Platelet count 275 | 275
Intelligence (multi-trait anal... 267 | 267
Mean platelet volume 253 | 253
IgG glycosylation 250 | 250
Mean corpuscular hemoglobin 238 | 238
Inflammatory bowel disease 235 | 235
Plateletcrit 227 | 227
Crohn's disease 215 | 215
Type 2 diabetes 210 | 210
Red blood cell count 191 | 191
Monocyte count 183 | 183
Red cell distribution width 182 | 182
Eosinophil counts 180 | 180
Neuroticism 180 | 180
Platelet distribution width 174 | 174
Monocyte percentage of white c... 173 | 173
Post bronchodilator FEV1 173 | 173
Sum eosinophil basophil counts 173 | 173
White blood cell count 172 | 172
3-hydroxy-1-methylpropylmercap... 166 | 166
Eosinophil percentage of granu... 163 | 163
Eosinophil percentage of white... 163 | 163
Reticulocyte fraction of red c... 163 | 163
Ulcerative colitis 163 | 163
Granulocyte percentage of myel... 162 | 162
Itch intensity from mosquito b... 162 | 162
Systemic lupus erythematosus 159 | 159
High light scatter reticulocyt... 158 | 158
Lymphocyte counts 158 | 158
Reticulocyte count 158 | 158
Neutrophil count 154 | 154
High light scatter reticulocyt... 153 | 153
Neutrophil percentage of granu... 153 | 153
3-hydroxypropylmercapturic aci... 150 | 150
Tonsillectomy 149 | 149
Diastolic blood pressure 144 | 144
Sum basophil neutrophil counts 140 | 140
Autism spectrum disorder or sc... 134 | 134
Myeloid white cell count 133 | 133
Granulocyte count 132 | 132
Sum neutrophil eosinophil coun... 129 | 129
Colorectal cancer 126 | 126
Alzheimer disease and age of o... 124 | 124
Multiple sclerosis 124 | 124
Cholesterol, total 123 | 123
Night sleep phenotypes 123 | 123
Lung cancer 122 | 122
Lymphocyte percentage of white... 122 | 122
Menarche (age at onset) 122 | 122
Neutrophil percentage of white... 121 | 121
Rheumatoid arthritis 121 | 121
Systolic blood pressure 120 | 120
Immature fraction of reticuloc... 118 | 118
Diisocyanate-induced asthma 116 | 116
HDL cholesterol 116 | 116
Allergic disease (asthma, hay ... 115 | 115
Educational attainment (years ... 114 | 114
Hematocrit 113 | 113
Hemoglobin concentration 112 | 112
LDL cholesterol 110 | 110
QT interval 110 | 110
Waist circumference adjusted f... 110 | 110
Mosquito bite size 107 | 107
Asthma 106 | 106
Lobe attachment (rater-scored ... 103 | 103
Peripheral arterial disease (t... 101 | 101
Pulse pressure 97 | 97
Bipolar disorder 94 | 94
Major depressive disorder 94 | 94
Prostate cancer 92 | 92
Parkinson's disease 90 | 90
Hip circumference adjusted for... 89 | 89
Metabolite levels 87 | 87
Triglycerides 87 | 87
Colonoscopy-negative controls ... 85 | 85
Mean corpuscular hemoglobin co... 85 | 85
Itch intensity from mosquito b... 84 | 84
Bipolar disorder and schizophr... 83 | 83
Resting heart rate 82 | 82
Macrophage inflammatory protei... 81 | 81
Migraine 81 | 81
Waist-to-hip ratio adjusted fo... 81 | 81
PR interval in Tripanosoma cru... 80 | 80
Cognitive performance 79 | 79
Glomerular filtration rate (cr... 78 | 78
Late-onset Alzheimer's disease 78 | 78
Waist circumference adjusted f... 75 | 75
Tuberculosis 73 | 73
Type 1 diabetes 73 | 73
Morning vs. evening chronotype 72 | 72

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Elongation of very long chain fatty acids protein 2 ELOVL2 Tbio Non-IDG -1.99271 91.8 122
Solute carrier organic anion transporter family member 1B1 SLCO1B1 Tchem Transporter -2.77788 574.0 124
Arylsulfatase A ARSA Tbio Enzyme -2.50334 319.0 337
Nuclear receptor subfamily 1 group I member 3 NR1I3 Tchem Nuclear Receptor -2.57140 281.2 304
Serine palmitoyltransferase 3 SPTLC3 Tbio Enzyme -1.26166 18.5 24
3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type 2 HSD3B2 Tclin Enzyme -2.06512 109.2 126
Glycosylphosphatidylinositol anchor attachment 1 protein GPAA1 Tbio Non-IDG -1.52498 33.6 113
Hydroxyacid oxidase 2 HAO2 Tchem Enzyme -1.22385 16.1 72
Solute carrier family 13 member 5 SLC13A5 Tchem Transporter -1.70063 50.0 86
TGF-beta receptor type-2 TGFBR2 Tchem Kinase -2.84120 665.1 548