Development Level

Tbio 31 | 11,445
Tchem 9 | 1,598
Tdark 8 | 6,588
Tclin 7 | 613

Collection

GPCR: IDG Consortium (Complete... 1 | 25

IMPC Phenotype

preweaning lethality, complete... 5 | 979
abnormal embryo size 4 | 220
abnormal behavior 3 | 298
abnormal kidney morphology 2 | 65
preweaning lethality, incomple... 2 | 499
abnormal body wall morphology 1 | 9
abnormal craniofacial morpholo... 1 | 33
abnormal epididymis morphology 1 | 42
abnormal facial morphology 1 | 17
abnormal head shape 1 | 10
abnormal motor capabilities-co... 1 | 5
abnormal outer ear morphology 1 | 3
abnormal retinal inner nuclear... 1 | 8
abnormal skin appearance 1 | 3
abnormal vibrissa morphology 1 | 25
anophthalmia 1 | 33
brachydactyly 1 | 19
cataract 1 | 92
decreased basophil cell number 1 | 16
decreased bone mineral content 1 | 151
decreased caudal vertebrae num... 1 | 53
decreased circulating choleste... 1 | 93
decreased circulating phosphat... 1 | 27
decreased lean body mass 1 | 135
decreased mean corpuscular hem... 1 | 31
decreased mean corpuscular vol... 1 | 79
decreased respiratory quotient 1 | 16
decreased total retina thickne... 1 | 17
edema 1 | 59
embryonic lethality prior to t... 1 | 278
enlarged epididymis 1 | 31
hypoactivity 1 | 132
increased CD4-positive, CD25-p... 1 | 1
increased KLRG1-positive NK ce... 1 | 1
increased NK cell number 1 | 3
increased anti-nuclear antigen... 1 | 19
increased body weight 1 | 25
increased bone mineral content 1 | 108
increased bone mineral density 1 | 72
increased effector memory CD4-... 1 | 1
increased fasted circulating g... 1 | 76
increased or absent threshold ... 1 | 101
long tibia 1 | 25
microphthalmia 1 | 26
pallor 1 | 34

Disease

Carcinoma 34 | 11,493
osteosarcoma 30 | 7,950
ovarian cancer 27 | 8,520
medulloblastoma, large-cell 26 | 6,241
psoriasis 25 | 6,694
glioblastoma 24 | 5,792
lung cancer 23 | 4,740
intraductal papillary-mucinous carcinoma (IPMC) 18 | 2,989
intraductal papillary-mucinous neoplasm (IPMN) 18 | 3,291
ependymoma 17 | 4,679
Cancer 16 | 2,499
atypical teratoid / rhabdoid tumor 15 | 5,112
non-small cell lung cancer 15 | 2,890
primitive neuroectodermal tumor 15 | 3,035
adult high grade glioma 14 | 3,801
group 3 medulloblastoma 14 | 4,104
interstitial cystitis 14 | 2,312
Breast cancer 13 | 3,578
Kidney cancer 13 | 2,613
adrenocortical carcinoma 13 | 1,428
lung adenocarcinoma 13 | 2,716
malignant mesothelioma 13 | 3,232
Astrocytoma, Pilocytic 12 | 3,081
diabetes mellitus 12 | 1,728
intraductal papillary-mucinous adenoma (IPMA) 12 | 2,955
ulcerative colitis 12 | 1,819
Acquired metabolic disease 11 | 336
invasive ductal carcinoma 11 | 2,951
oligodendroglioma 11 | 2,850
Obesity 10 | 678
pancreatic ductal adenocarcinoma liver metastasis 10 | 1,962
tuberculosis 10 | 2,010
Osteoporosis 9 | 363
cystic fibrosis 9 | 1,696
pituitary cancer 9 | 1,972
Intellectual disability 8 | 1,016
Liver carcinoma 8 | 240
Type 2 diabetes mellitus 8 | 272
astrocytic glioma 8 | 2,597
breast carcinoma 8 | 1,638
ductal carcinoma in situ 8 | 1,745
group 4 medulloblastoma 8 | 1,855
pancreatic cancer 8 | 2,398
subependymal giant cell astrocytoma 8 | 2,287
Carcinoma, Hepatocellular 7 | 228
Diabetes Mellitus, Type 2 7 | 142
Orbital separation excessive 7 | 244
Rheumatoid arthritis 7 | 1,191
Schizophrenia 7 | 1,160
Short stature 7 | 531
lung carcinoma 7 | 2,843
Alzheimer's disease 6 | 658
Autosomal recessive predisposition 6 | 1,442
Breast Neoplasms 6 | 445
Diabetes Mellitus, Non-Insulin-Dependent 6 | 145
Dull intelligence 6 | 645
Endometriosis 6 | 540
Fetal Growth Retardation 6 | 189
Hypoplastic mandible condyle 6 | 275
Infant, Small for Gestational Age 6 | 176
Intrauterine retardation 6 | 176
Low intelligence 6 | 645
Mammary Neoplasms 6 | 425
Mandibular hypoplasia 6 | 275
Mental Retardation 6 | 645
Mental deficiency 6 | 645
Micrognathism 6 | 275
Pick disease 6 | 1,894
Poor school performance 6 | 645
astrocytoma 6 | 1,146
Atopic dermatitis 5 | 952
Birth Weight 5 | 13
Cognitive delay 5 | 608
Concave bridge of nose 5 | 195
Crohn's disease 5 | 321
Depressed nasal bridge 5 | 195
Depressed nasal root/bridge 5 | 195
Global developmental delay 5 | 608
Long philtrum 5 | 137
Mental and motor retardation 5 | 608
Polycystic ovary syndrome 5 | 360
cutaneous lupus erythematosus 5 | 1,057
gastric carcinoma 5 | 807
juvenile dermatomyositis 5 | 1,187
medulloblastoma 5 | 720
pediatric high grade glioma 5 | 1,064
Asthma 4 | 385
Bilateral fifth finger clinodactyly 4 | 110
Broad flat nasal bridge 4 | 236
Congenital Epicanthus 4 | 177
Delayed bone age 4 | 136
Duchenne muscular dystrophy 4 | 601
Lens Opacities 4 | 231
Nasal bridge wide 4 | 236
Small nose 4 | 132
Waldenstrons macroglobulinemia 4 | 765
aldosterone-producing adenoma 4 | 665
colon cancer 4 | 1,478
dermatomyositis 4 | 966
nasopharyngeal carcinoma 4 | 1,058

Tissue

Endocrine System 54 | 18,159
Female tissues 54 | 17,400
Skin and soft tissues 53 | 17,230
Urinary Tract 53 | 16,678
Nervous System 52 | 16,725
Blood and immune system 51 | 16,909
Digestive Tract 51 | 17,369
Liver and Pancreas 51 | 16,750
Male tissues 51 | 17,142
Respiratory system 51 | 16,393
Cardiovascular System 46 | 15,192

Target Family

Non-IDG 23 | 12,091
Transcription Factor 9 | 1,400
Enzyme 8 | 4,145
GPCR 4 | 408
Epigenetic 3 | 242
Kinase 3 | 634
Transporter 3 | 473
Ion Channel 1 | 344
Nuclear Receptor 1 | 48

GWAS Trait

Birth weight 55 | 55
Obesity-related traits 569 | 569
Schizophrenia 533 | 533
Breast cancer 492 | 492
Body mass index 379 | 379
Height 369 | 369
Coronary artery disease 367 | 367
Blood protein levels 351 | 351
Post bronchodilator FEV1-FVC r... 308 | 308
Mean corpuscular volume 283 | 283
Platelet count 275 | 275
Intelligence (multi-trait anal... 267 | 267
Mean platelet volume 253 | 253
IgG glycosylation 250 | 250
Mean corpuscular hemoglobin 238 | 238
Inflammatory bowel disease 235 | 235
Plateletcrit 227 | 227
Crohn's disease 215 | 215
Type 2 diabetes 210 | 210
Red blood cell count 191 | 191
Monocyte count 183 | 183
Red cell distribution width 182 | 182
Eosinophil counts 180 | 180
Neuroticism 180 | 180
Platelet distribution width 174 | 174
Monocyte percentage of white c... 173 | 173
Post bronchodilator FEV1 173 | 173
Sum eosinophil basophil counts 173 | 173
White blood cell count 172 | 172
3-hydroxy-1-methylpropylmercap... 166 | 166
Eosinophil percentage of granu... 163 | 163
Eosinophil percentage of white... 163 | 163
Reticulocyte fraction of red c... 163 | 163
Ulcerative colitis 163 | 163
Granulocyte percentage of myel... 162 | 162
Itch intensity from mosquito b... 162 | 162
Systemic lupus erythematosus 159 | 159
High light scatter reticulocyt... 158 | 158
Lymphocyte counts 158 | 158
Reticulocyte count 158 | 158
Blood metabolite levels 157 | 157
Neutrophil count 154 | 154
High light scatter reticulocyt... 153 | 153
Neutrophil percentage of granu... 153 | 153
3-hydroxypropylmercapturic aci... 150 | 150
Tonsillectomy 149 | 149
Diastolic blood pressure 144 | 144
Sum basophil neutrophil counts 140 | 140
Autism spectrum disorder or sc... 134 | 134
Myeloid white cell count 133 | 133
Granulocyte count 132 | 132
Sum neutrophil eosinophil coun... 129 | 129
Colorectal cancer 126 | 126
Alzheimer disease and age of o... 124 | 124
Multiple sclerosis 124 | 124
Cholesterol, total 123 | 123
Night sleep phenotypes 123 | 123
Lung cancer 122 | 122
Lymphocyte percentage of white... 122 | 122
Menarche (age at onset) 122 | 122
Neutrophil percentage of white... 121 | 121
Rheumatoid arthritis 121 | 121
Systolic blood pressure 120 | 120
Immature fraction of reticuloc... 118 | 118
Diisocyanate-induced asthma 116 | 116
HDL cholesterol 116 | 116
Allergic disease (asthma, hay ... 115 | 115
Educational attainment (years ... 114 | 114
Hematocrit 113 | 113
Hemoglobin concentration 112 | 112
LDL cholesterol 110 | 110
QT interval 110 | 110
Waist circumference adjusted f... 110 | 110
Mosquito bite size 107 | 107
Asthma 106 | 106
Lobe attachment (rater-scored ... 103 | 103
Peripheral arterial disease (t... 101 | 101
Pulse pressure 97 | 97
Bipolar disorder 94 | 94
Major depressive disorder 94 | 94
Prostate cancer 92 | 92
Parkinson's disease 90 | 90
Hip circumference adjusted for... 89 | 89
Metabolite levels 87 | 87
Triglycerides 87 | 87
Colonoscopy-negative controls ... 85 | 85
Mean corpuscular hemoglobin co... 85 | 85
Itch intensity from mosquito b... 84 | 84
Bipolar disorder and schizophr... 83 | 83
Resting heart rate 82 | 82
Macrophage inflammatory protei... 81 | 81
Migraine 81 | 81
Waist-to-hip ratio adjusted fo... 81 | 81
PR interval in Tripanosoma cru... 80 | 80
Cognitive performance 79 | 79
Glomerular filtration rate (cr... 78 | 78
Late-onset Alzheimer's disease 78 | 78
Waist circumference adjusted f... 75 | 75
Tuberculosis 73 | 73
Type 1 diabetes 73 | 73
Morning vs. evening chronotype 72 | 72

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Hedgehog-interacting protein HHIP Tbio Non-IDG -1.83526 65.4 193
Solute carrier family 45 member 4 SLC45A4 Tdark Transporter 0.30 0.50 12
ATPase family AAA domain-containing protein 2B ATAD2B Tchem Epigenetic 0.27 1.01 18
Rab GTPase-activating protein 1 RABGAP1 Tbio Enzyme -0.72004 3.69 184
Mast cell carboxypeptidase A CPA3 Tchem Enzyme -1.72972 50.2 151
Sterol regulatory element-binding protein 2 SREBF2 Tchem Transcription Factor -2.61148 361.0 205
Leucine-, glutamate- and lysine-rich protein 1 LEKR1 Tdark Non-IDG 0.00000 17
Retinoblastoma-associated protein RB1 Tchem Non-IDG -3.07052 1137.4 2150
Carbohydrate-responsive element-binding protein MLXIPL Tbio Transcription Factor -2.29554 206.7 235
Ligand-dependent nuclear receptor corepressor-like protein LCORL Tbio Transcription Factor -1.37418 24.5 108