Development Level

Tbio 59 | 11,445
Tdark 13 | 6,588
Tchem 9 | 1,598
Tclin 2 | 613

Collection

Ion Channel: IDG Consortium (T... 3 | 99
GPCR: IDG Consortium (Targets) 1 | 126
Kinase: IDG Consortium (Target... 1 | 125

IMPC Phenotype

preweaning lethality, complete... 5 | 979
abnormal behavior 3 | 298
abnormal lens morphology 2 | 81
abnormal testis morphology 2 | 43
cataract 2 | 92
decreased circulating bilirubi... 2 | 19
decreased hemoglobin content 2 | 68
embryonic lethality prior to o... 2 | 239
embryonic lethality prior to t... 2 | 278
prenatal lethality prior to he... 2 | 87
preweaning lethality, incomple... 2 | 499
small testis 2 | 58
abnormal bone structure 1 | 187
abnormal embryo size 1 | 220
abnormal gait 1 | 69
abnormal heart morphology 1 | 162
abnormal lung morphology 1 | 26
abnormal vitreous body morphol... 1 | 10
decreased basophil cell number 1 | 16
decreased bone mineral density 1 | 126
decreased circulating alkaline... 1 | 46
decreased circulating free fat... 1 | 31
decreased circulating glucose ... 1 | 126
decreased circulating serum al... 1 | 82
decreased circulating triglyce... 1 | 79
decreased erythrocyte cell num... 1 | 62
decreased lymphocyte cell numb... 1 | 83
decreased mean corpuscular hem... 1 | 50
decreased mean corpuscular vol... 1 | 79
decreased red blood cell distr... 1 | 41
decreased vertical activity 1 | 208
enlarged adrenal glands 1 | 3
enlarged heart 1 | 210
enlarged kidney 1 | 14
enlarged uterus 1 | 11
hydrometra 1 | 53
hyperactivity 1 | 148
impaired glucose tolerance 1 | 75
improved glucose tolerance 1 | 79
increased bone mineral density 1 | 72
increased circulating alkaline... 1 | 122
increased circulating lipase l... 1 | 3
increased circulating sodium l... 1 | 71
increased fasted circulating g... 1 | 76
increased heart weight 1 | 62
increased monocyte cell number 1 | 63
increased red blood cell distr... 1 | 34
increased startle reflex 1 | 112
irregularly shaped pupil 1 | 7
male infertility 1 | 123
polycystic kidney 1 | 15
prenatal lethality 1 | 28
small adrenal glands 1 | 16
small lymph nodes 1 | 1
thrombocytosis 1 | 27

Disease

Carcinoma 64 | 11,493
glioblastoma 43 | 5,792
medulloblastoma, large-cell 43 | 6,241
ovarian cancer 42 | 8,520
osteosarcoma 40 | 7,950
psoriasis 40 | 6,694
atypical teratoid / rhabdoid tumor 36 | 5,112
ependymoma 35 | 4,679
Kidney cancer 31 | 2,613
Astrocytoma, Pilocytic 30 | 3,081
oligodendroglioma 30 | 2,850
adult high grade glioma 29 | 3,801
astrocytic glioma 27 | 2,597
primitive neuroectodermal tumor 26 | 3,035
Cognitive disorder 25 | 50
group 3 medulloblastoma 25 | 4,104
intraductal papillary-mucinous neoplasm (IPMN) 24 | 3,291
lung cancer 24 | 4,740
malignant mesothelioma 24 | 3,232
Breast cancer 23 | 3,578
intraductal papillary-mucinous carcinoma (IPMC) 22 | 2,989
lung carcinoma 22 | 2,843
invasive ductal carcinoma 21 | 2,951
pituitary cancer 20 | 1,972
intraductal papillary-mucinous adenoma (IPMA) 19 | 2,955
pancreatic cancer 19 | 2,398
cystic fibrosis 18 | 1,696
Pick disease 17 | 1,894
group 4 medulloblastoma 15 | 1,855
lung adenocarcinoma 15 | 2,716
non-small cell lung cancer 15 | 2,890
tuberculosis 15 | 2,010
Schizophrenia 14 | 1,160
interstitial cystitis 13 | 2,312
subependymal giant cell astrocytoma 13 | 2,287
Bipolar Disorder 12 | 666
pancreatic ductal adenocarcinoma liver metastasis 12 | 1,962
Melanoma 10 | 711
colon cancer 10 | 1,478
pediatric high grade glioma 10 | 1,064
Cancer 9 | 2,499
ductal carcinoma in situ 9 | 1,745
Autosomal recessive predisposition 8 | 1,442
Intellectual disability 8 | 1,016
cutaneous lupus erythematosus 8 | 1,057
nasopharyngeal carcinoma 8 | 1,058
primary pancreatic ductal adenocarcinoma 8 | 1,109
Alzheimer's disease 7 | 658
Liver cancer 7 | 604
Muscle hypotonia 7 | 571
Rheumatoid arthritis 7 | 1,191
Skin cancer 7 | 469
acute quadriplegic myopathy 7 | 1,158
breast carcinoma 7 | 1,638
juvenile dermatomyositis 7 | 1,187
ulcerative colitis 7 | 1,819
Duchenne muscular dystrophy 6 | 601
Seizures 6 | 596
dermatomyositis 6 | 966
medulloblastoma 6 | 720
Acquired metabolic disease 5 | 336
Attention deficit hyperactivity disorder 5 | 278
Autistic Disorder 5 | 364
Epilepsy 5 | 792
Liver Cirrhosis, Experimental 5 | 769
Major Depressive Disorder 5 | 301
Multiple myeloma 5 | 1,332
Myopia 5 | 176
Neurodegenerative disease 5 | 414
Neuropathy 5 | 261
Obesity 5 | 678
Short stature 5 | 531
adrenocortical carcinoma 5 | 1,428
astrocytoma 5 | 1,146
autosomal dominant Emery-Dreifuss muscular dystrophy 5 | 510
gastric carcinoma 5 | 807
inflammatory breast cancer 5 | 286
urothelial carcinoma 5 | 318
Acquired scoliosis 4 | 281
Broad flat nasal bridge 4 | 236
Cardiovascular system disease 4 | 246
Curvature of spine 4 | 282
Down syndrome 4 | 499
Dull intelligence 4 | 645
Globe disease 4 | 67
Hydrolethalus syndrome 4 | 128
Low intelligence 4 | 645
Mental Depression 4 | 333
Mental Retardation 4 | 645
Mental deficiency 4 | 645
Multiple Sclerosis 4 | 540
Nasal bridge wide 4 | 236
Osteoporosis 4 | 363
Peripheral Neuropathy 4 | 134
Poor school performance 4 | 645
Short neck 4 | 140
Unipolar Depression 4 | 250
hereditary spastic paraplegia 4 | 318
mucosa-associated lymphoid tissue lymphoma 4 | 484
primary Sjogren syndrome 4 | 735

Tissue

Endocrine System 81 | 18,159
Digestive Tract 80 | 17,369
Female tissues 80 | 17,400
Male tissues 80 | 17,142
Urinary Tract 79 | 16,678
Liver and Pancreas 78 | 16,750
Nervous System 78 | 16,725
Skin and soft tissues 78 | 17,230
Blood and immune system 72 | 16,909
Respiratory system 72 | 16,393
Cardiovascular System 68 | 15,192

Target Family

Non-IDG 49 | 12,091
Enzyme 12 | 4,145
Ion Channel 6 | 344
Transporter 5 | 473
Epigenetic 4 | 242
GPCR 2 | 408
Kinase 2 | 634
Transcription Factor 2 | 1,400
Nuclear Receptor 1 | 48

GWAS Trait

Bipolar disorder and schizophr... 83 | 83
Obesity-related traits 569 | 569
Schizophrenia 533 | 533
Breast cancer 492 | 492
Body mass index 379 | 379
Height 369 | 369
Coronary artery disease 367 | 367
Blood protein levels 351 | 351
Post bronchodilator FEV1-FVC r... 308 | 308
Mean corpuscular volume 283 | 283
Platelet count 275 | 275
Intelligence (multi-trait anal... 267 | 267
Mean platelet volume 253 | 253
IgG glycosylation 250 | 250
Mean corpuscular hemoglobin 238 | 238
Inflammatory bowel disease 235 | 235
Plateletcrit 227 | 227
Crohn's disease 215 | 215
Type 2 diabetes 210 | 210
Red blood cell count 191 | 191
Monocyte count 183 | 183
Red cell distribution width 182 | 182
Eosinophil counts 180 | 180
Neuroticism 180 | 180
Platelet distribution width 174 | 174
Monocyte percentage of white c... 173 | 173
Post bronchodilator FEV1 173 | 173
Sum eosinophil basophil counts 173 | 173
White blood cell count 172 | 172
3-hydroxy-1-methylpropylmercap... 166 | 166
Eosinophil percentage of granu... 163 | 163
Eosinophil percentage of white... 163 | 163
Reticulocyte fraction of red c... 163 | 163
Ulcerative colitis 163 | 163
Granulocyte percentage of myel... 162 | 162
Itch intensity from mosquito b... 162 | 162
Systemic lupus erythematosus 159 | 159
High light scatter reticulocyt... 158 | 158
Lymphocyte counts 158 | 158
Reticulocyte count 158 | 158
Blood metabolite levels 157 | 157
Neutrophil count 154 | 154
High light scatter reticulocyt... 153 | 153
Neutrophil percentage of granu... 153 | 153
3-hydroxypropylmercapturic aci... 150 | 150
Tonsillectomy 149 | 149
Diastolic blood pressure 144 | 144
Sum basophil neutrophil counts 140 | 140
Autism spectrum disorder or sc... 134 | 134
Myeloid white cell count 133 | 133
Granulocyte count 132 | 132
Sum neutrophil eosinophil coun... 129 | 129
Colorectal cancer 126 | 126
Alzheimer disease and age of o... 124 | 124
Multiple sclerosis 124 | 124
Cholesterol, total 123 | 123
Night sleep phenotypes 123 | 123
Lung cancer 122 | 122
Lymphocyte percentage of white... 122 | 122
Menarche (age at onset) 122 | 122
Neutrophil percentage of white... 121 | 121
Rheumatoid arthritis 121 | 121
Systolic blood pressure 120 | 120
Immature fraction of reticuloc... 118 | 118
Diisocyanate-induced asthma 116 | 116
HDL cholesterol 116 | 116
Allergic disease (asthma, hay ... 115 | 115
Educational attainment (years ... 114 | 114
Hematocrit 113 | 113
Hemoglobin concentration 112 | 112
LDL cholesterol 110 | 110
QT interval 110 | 110
Waist circumference adjusted f... 110 | 110
Mosquito bite size 107 | 107
Asthma 106 | 106
Lobe attachment (rater-scored ... 103 | 103
Peripheral arterial disease (t... 101 | 101
Pulse pressure 97 | 97
Bipolar disorder 94 | 94
Major depressive disorder 94 | 94
Prostate cancer 92 | 92
Parkinson's disease 90 | 90
Hip circumference adjusted for... 89 | 89
Metabolite levels 87 | 87
Triglycerides 87 | 87
Colonoscopy-negative controls ... 85 | 85
Mean corpuscular hemoglobin co... 85 | 85
Itch intensity from mosquito b... 84 | 84
Resting heart rate 82 | 82
Macrophage inflammatory protei... 81 | 81
Migraine 81 | 81
Waist-to-hip ratio adjusted fo... 81 | 81
PR interval in Tripanosoma cru... 80 | 80
Cognitive performance 79 | 79
Glomerular filtration rate (cr... 78 | 78
Late-onset Alzheimer's disease 78 | 78
Waist circumference adjusted f... 75 | 75
Tuberculosis 73 | 73
Type 1 diabetes 73 | 73
Morning vs. evening chronotype 72 | 72

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Beta-1,4-galactosyltransferase 1 B4GALT1 Tbio Enzyme -2.34454 211.1 130
Calcium-activated potassium channel subunit beta-2 KCNMB2 Tbio Ion Channel 1.28 0.09 191
A disintegrin and metalloproteinase with thrombospondin motifs 6 ADAMTS6 Tdark Enzyme -0.67364 4.37 40
Glypican-6 GPC6 Tbio Non-IDG -1.33560 21.9 125
Mitotic spindle assembly checkpoint protein MAD1 MAD1L1 Tbio Non-IDG -1.17500 13.6 283
Beta-crystallin B1 CRYBB1 Tbio Non-IDG -1.89050 77.2 109
Contactin-associated protein-like 2 CNTNAP2 Tbio Non-IDG -2.36156 228.4 191
G-protein coupled receptor 20 GPR20 Tdark GPCR -0.12265 1.50 189
Mitochondrial peptide methionine sulfoxide reductase MSRA Tbio Enzyme -1.92325 88.1 167
Erythrocyte band 7 integral membrane protein STOM Tbio Non-IDG -2.27504 176.9 163