Development Level

Tbio 11 | 10,625
Tdark 5 | 7,003

IMPC Phenotype

decreased circulating fructosa... 1 | 31
decreased total body fat amoun... 1 | 186
decreased vertical activity 1 | 22
increased bone mineral content 1 | 92
increased bone mineral density 1 | 52
increased lean body mass 1 | 107
preweaning lethality, complete... 1 | 633

Disease

medulloblastoma, large-cell 11 | 6,234
ovarian cancer 10 | 8,491
Carcinoma 7 | 2,147
atypical teratoid / rhabdoid tumor 7 | 4,369
glioblastoma 7 | 5,572
osteosarcoma 7 | 7,933
primitive neuroectodermal tumor 7 | 3,031
psoriasis 7 | 6,685
Pick disease 6 | 1,893
intraductal papillary-mucinous adenoma (IPMA) 6 | 2,956
lung carcinoma 6 | 2,844
pilocytic astrocytoma 6 | 3,086
Breast cancer 5 | 3,098
oligodendroglioma 5 | 2,849
adult high grade glioma 4 | 2,148
astrocytoma 4 | 1,493
ependymoma 4 | 2,514
group 3 medulloblastoma 4 | 2,254
interstitial cystitis 4 | 2,299
intraductal papillary-mucinous carcinoma (IPMC) 4 | 2,988
invasive ductal carcinoma 4 | 2,950
malignant mesothelioma 4 | 3,163
pancreatic cancer 4 | 2,300
pediatric high grade glioma 4 | 2,712
posterior fossa group A ependymoma 4 | 1,511
posterior fossa group B ependymoma 4 | 1,530
Obesity 3 | 616
Rheumatoid Arthritis 3 | 1,170
breast carcinoma 3 | 1,614
ductal carcinoma in situ 3 | 1,745
group 4 medulloblastoma 3 | 1,875
juvenile dermatomyositis 3 | 1,189
lung cancer 3 | 4,473
pituitary cancer 3 | 1,972
subependymal giant cell astrocytoma 3 | 2,287
Atopic dermatitis 2 | 944
Barrett's esophagus 2 | 185
Bipolar Disorder 2 | 266
Cardiovascular system disease 2 | 194
Chronic obstructive pulmonary disease 2 | 147
Colorectal Neoplasms 2 | 217
Duchenne muscular dystrophy 2 | 602
Esophageal cancer 2 | 30
Hydrolethalus syndrome 2 | 128
Juvenile arthritis 2 | 124
Pulmonary function (finding) 2 | 33
Type 2 diabetes mellitus 2 | 192
astrocytic glioma 2 | 2,241
autosomal dominant Emery-Dreifuss muscular dystrophy 2 | 499
dermatomyositis 2 | 966
esophageal adenocarcinoma 2 | 737
intraductal papillary-mucinous neoplasm (IPMN) 2 | 3,289
lung adenocarcinoma 2 | 2,714
medulloblastoma 2 | 1,524
nasopharyngeal carcinoma 2 | 1,056
pancreatic carcinoma 2 | 567
primary pancreatic ductal adenocarcinoma 2 | 1,271
sonic hedgehog group medulloblastoma 2 | 1,482
tuberculosis 2 | 1,563
Acquired metabolic disease 1 | 267
Alopecia 1 | 55
Alzheimer's disease 1 | 644
Amyotrophic Lateral Sclerosis 1 | 432
Blindness 1 | 84
Cancer 1 | 2,346
Choreatic disease 1 | 27
Colonic Neoplasms 1 | 126
Colorectal Cancer 1 | 62
Cutis laxa 1 | 28
Diabetes Mellitus, Non-Insulin-Dependent 1 | 161
Epilepsy 1 | 346
Gastroesophageal reflux disease 1 | 37
Heart disease 1 | 279
Huntington's disease 1 | 72
Hyperplasia 1 | 26
Major Depressive Disorder 1 | 106
Malignant neoplasm of breast 1 | 63
Mammary Neoplasms 1 | 410
Metabolic syndrome X 1 | 155
Multiple Sclerosis 1 | 498
Neurodegenerative disease 1 | 383
Neutropenia 1 | 78
Nonsyndromic deafness 1 | 121
Prostate cancer 1 | 172
Retinitis pigmentosa 1 | 156
Squamous cell carcinoma 1 | 96
Squamous cell carcinoma of esophagus 1 | 82
Stomach Neoplasms 1 | 282
Usher syndrome 1 | 34
Venous Thromboembolism 1 | 34
chronic rhinosinusitis 1 | 512
cystic fibrosis 1 | 1,670
dentatorubral-pallidoluysian atrophy 1 | 21
head and neck cancer and chronic obstructive pulmonary disease 1 | 237
hereditary spastic paraplegia 1 | 313
limb girdle muscular dystrophy 2A 1 | 156
permanent atrial fibrillation 1 | 44
progressive supranuclear palsy 1 | 674
sarcoidosis 1 | 368
tuberculosis and treatment for 6 months 1 | 686

Tissue

Cardiovascular System 16 | 17,957
Digestive Tract 16 | 18,472
Endocrine System 16 | 18,511
Female tissues 16 | 18,646
Liver and Pancreas 16 | 18,135
Male tissues 16 | 17,968
Nervous System 16 | 18,560
Skin and soft tissues 16 | 18,114
Urinary Tract 16 | 18,443
Blood and immune system 15 | 17,994
Respiratory system 15 | 17,483

Target Family

Non-IDG 11 | 11,969
Enzyme 3 | 4,146
Transcription Factor 1 | 1,400
Transporter 1 | 473

GWAS Trait

Bipolar disorder (body mass in... 16 | 16
Obesity-related traits 380 | 380
Schizophrenia 334 | 334
Height 250 | 250
Post bronchodilator FEV1-FVC r... 191 | 191
Body mass index 180 | 180
IgG glycosylation 162 | 162
Inflammatory bowel disease 117 | 117
Post bronchodilator FEV1 111 | 111
Crohn's disease 110 | 110
Blood metabolite levels 103 | 103
Type 2 diabetes 94 | 94
3-hydroxy-1-methylpropylmercap... 93 | 93
3-hydroxypropylmercapturic aci... 92 | 92
Ulcerative colitis 89 | 89
Platelet count 79 | 79
Systemic lupus erythematosus 78 | 78
HDL cholesterol 76 | 76
Rheumatoid arthritis 74 | 74
Cholesterol, total 73 | 73
Menarche (age at onset) 73 | 73
Diisocyanate-induced asthma 72 | 72
Multiple sclerosis 68 | 68
LDL cholesterol 67 | 67
QT interval 58 | 58
Metabolite levels 55 | 55
Atopic dermatitis 54 | 54
Bipolar disorder and schizophr... 54 | 54
Breast cancer 54 | 54
Prostate cancer 54 | 54
Triglycerides 53 | 53
Bipolar disorder 52 | 52
HIV-1 control 50 | 50
Post bronchodilator FEV1-FVC r... 50 | 50
HIV-1 viral setpoint 49 | 49
Cognitive performance 48 | 48
Amyotrophic lateral sclerosis ... 46 | 46
Bone mineral density 46 | 46
Clozapine-induced agranulocyto... 46 | 46
Attention deficit hyperactivit... 44 | 44
Blood pressure 44 | 44
Coronary heart disease 43 | 43
Glomerular filtration rate (cr... 43 | 43
Parkinson's disease 43 | 43
Type 1 diabetes 42 | 42
PR interval in Tripanosoma cru... 40 | 40
Post bronchodilator FEV1 in CO... 39 | 39
Alzheimer's disease (cognitive... 38 | 38
Educational attainment 38 | 38
Pulmonary function 38 | 38
Diffuse large B cell lymphoma 37 | 37
Inflammatory skin disease 37 | 37
Beta-2 microglubulin plasma le... 36 | 36
Glucose homeostasis traits 36 | 36
Urate levels 36 | 36
Blood metabolite ratios 35 | 35
Psoriasis 35 | 35
Autism spectrum disorder, atte... 34 | 34
Migraine 33 | 33
Coronary artery disease 32 | 32
Metabolic traits 32 | 32
Waist-to-hip ratio adjusted fo... 32 | 32
Cognitive function 31 | 31
Colorectal cancer 31 | 31
Amyotrophic lateral sclerosis 30 | 30
Myopia (pathological) 30 | 30
Obesity 30 | 30
Response to amphetamines 30 | 30
Systolic blood pressure 30 | 30
Alzheimer's disease (late onse... 29 | 29
Celiac disease 29 | 29
Phospholipid levels (plasma) 29 | 29
Red blood cell traits 29 | 29
Advanced age-related macular d... 28 | 28
Dental caries 28 | 28
Fibrinogen levels 28 | 28
Parental extreme longevity (95... 28 | 28
Pulmonary function (interactio... 28 | 28
Asthma 27 | 27
Cognitive decline rate in late... 27 | 27
Glomerular filtration rate in ... 27 | 27
Longevity 27 | 27
Mean platelet volume 27 | 27
Chronic kidney disease 26 | 26
Diabetic kidney disease 26 | 26
Diastolic blood pressure 26 | 26
Coronary artery calcification 25 | 25
Metabolic syndrome 25 | 25
Pancreatic cancer 25 | 25
Protein quantitative trait loc... 25 | 25
Hypertension 24 | 24
Migraine - clinic-based 24 | 24
Parental longevity (combined p... 24 | 24
Primary biliary cirrhosis 24 | 24
Thiazide-induced adverse metab... 24 | 24
Menopause (age at onset) 23 | 23
Response to antipsychotic trea... 23 | 23
Age-related macular degenerati... 22 | 22
Immune response to smallpox va... 22 | 22
Mild influenza (H1N1) infectio... 22 | 22
Sudden cardiac arrest 22 | 22

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
WW domain-containing oxidoreductase WWOX Tbio Enzyme -3.56179 2916.0 232
Ras and Rab interactor 2 RIN2 Tbio Non-IDG -1.42926 24.1 51
F-box/LRR-repeat protein 17 FBXL17 Tbio Non-IDG -0.47227 3.03 65
Transcription factor 7-like 2 TCF7L2 Tbio Transcription Factor -2.60797 439.7 281
Teashirt homolog 2 TSHZ2 Tbio Non-IDG -0.01649 3.43 78
Cadherin-23 CDH23 Tbio Non-IDG -1.98033 103.4 181
Protein FAM19A5 FAM19A5 Tdark Non-IDG -0.08831 1.64 7
Disintegrin and metalloproteinase domain-containing protein 19 ADAM19 Tbio Enzyme -1.56857 41.8 160
Transmembrane protein 132B TMEM132B Tdark Non-IDG 0.00000 1.00 25
Clathrin heavy chain linker domain-containing protein 1 CLHC1 Tdark Non-IDG 1.49 0.03 10