Development Level

Tbio 5 | 11,445

IMPC Phenotype

abnormal embryo size 1 | 220
abnormal epididymis morphology 1 | 42
abnormal seminal vesicle morph... 1 | 114
abnormal vibrissa morphology 1 | 25
absent vibrissae 1 | 12
decreased circulating LDL chol... 1 | 38
decreased circulating alanine ... 1 | 47
decreased circulating aspartat... 1 | 34
decreased circulating calcium ... 1 | 36
decreased circulating iron lev... 1 | 32
decreased lactate dehydrogenas... 1 | 16
edema 1 | 59
embryonic growth retardation 1 | 106
embryonic lethality prior to o... 1 | 239
enlarged epididymis 1 | 31
hyperactivity 1 | 148
preweaning lethality, incomple... 1 | 499

Disease

ovarian cancer 4 | 8,520
Carcinoma 3 | 11,493
Coronary artery disease 3 | 268
glioblastoma 3 | 5,792
medulloblastoma, large-cell 3 | 6,241
osteosarcoma 3 | 7,950
psoriasis 3 | 6,694
Astrocytoma, Pilocytic 2 | 3,081
Breast cancer 2 | 3,578
Cancer 2 | 2,499
Essential Hypertension 2 | 94
Hypertension 2 | 396
Kidney disease 2 | 430
Rheumatoid arthritis 2 | 1,191
Type 2 diabetes mellitus 2 | 272
adult high grade glioma 2 | 3,801
atypical teratoid / rhabdoid tumor 2 | 5,112
diabetes mellitus 2 | 1,728
ependymoma 2 | 4,679
lung cancer 2 | 4,740
medulloblastoma 2 | 720
pituitary cancer 2 | 1,972
primitive neuroectodermal tumor 2 | 3,035
substance-related disorder 2 | 162
Acquired metabolic disease 1 | 336
Adenoma 1 | 167
Alcoholic Intoxication, Chronic 1 | 289
Amyotrophic lateral sclerosis 1 | 451
Anemia 1 | 365
Atherosclerosis 1 | 291
Atopic dermatitis 1 | 952
Autosomal dominant nonsyndromic deafness 25 1 | 6
Barrett's esophagus 1 | 182
Breast Neoplasms 1 | 445
Breast fibroadenoma 1 | 8
Capillary hemangioma 1 | 12
Cavernous hemangioma 1 | 11
Celiac disease 1 | 116
Cell Transformation, Neoplastic 1 | 97
Cerebrovascular disease 1 | 238
Chronic obstructive pulmonary disease 1 | 184
Depressive disorder 1 | 409
Diabetes Mellitus, Non-Insulin-Dependent 1 | 145
Diabetes Mellitus, Type 2 1 | 142
Exophthalmos 1 | 112
Eye and adnexa disease 1 | 18
Gaucher disease type 1 1 | 180
Heart disease 1 | 306
Hemangioma 1 | 69
Human immunodeficiency virus infectious disease 1 | 138
Hypersensitivity reaction type II disease 1 | 253
Leber congenital amaurosis 1 | 69
Leiomyoma 1 | 32
Lipoma 1 | 32
Liver disease 1 | 237
Lymphangioma 1 | 9
Lymphatic system disease 1 | 15
Lymphoproliferative syndrome 1 | 58
Major Depressive Disorder 1 | 301
Mammary Neoplasms 1 | 425
Mastocytosis 1 | 27
Melanoma 1 | 711
Mental Depression 1 | 333
Metabolic syndrome X 1 | 52
Mood Disorders 1 | 184
Mucositis 1 | 29
Neoplastic Cell Transformation 1 | 89
Neurilemmoma 1 | 23
Neurofibromatosis 1 | 40
Neutropenia 1 | 72
Nonorganic psychosis 1 | 84
Osteoarthritis 1 | 184
Osteoporosis 1 | 363
Parkinson's disease 1 | 392
Pick disease 1 | 1,894
Pneumonia 1 | 174
Polycystic ovary syndrome 1 | 360
Polycythemia vera 1 | 27
Psychotic Disorders 1 | 151
Schnyder Corneal Dystrophy 1 | 23
Severe combined immunodeficiency 1 | 51
Skin disease 1 | 66
Thalassemia 1 | 53
Thrombocytopenia 1 | 197
Thrombocytosis 1 | 38
Unipolar Depression 1 | 250
Waldenstrons macroglobulinemia 1 | 765
Weight Gain 1 | 100
Wiskott-Aldrich syndrome 1 | 30
active Crohn's disease 1 | 922
active ulcerative colitis 1 | 764
adrenocortical carcinoma 1 | 1,428
autosomal dominant Emery-Dreifuss muscular dystrophy 1 | 510
chronic lymphosyte leukemia 1 | 204
cystic fibrosis 1 | 1,696
esophageal cancer 1 | 22
hereditary spastic paraplegia 1 | 318
lung adenocarcinoma 1 | 2,716
subependymal giant cell astrocytoma 1 | 2,287
tuberculosis 1 | 2,010

Tissue

Blood and immune system 5 | 16,909
Cardiovascular System 5 | 15,192
Digestive Tract 5 | 17,369
Endocrine System 5 | 18,159
Female tissues 5 | 17,400
Liver and Pancreas 5 | 16,750
Male tissues 5 | 17,142
Nervous System 5 | 16,725
Respiratory system 5 | 16,393
Skin and soft tissues 5 | 17,230
Urinary Tract 5 | 16,678

Target Family

Enzyme 2 | 4,145
Non-IDG 2 | 12,091
Transporter 1 | 473

GWAS Trait

Biomedical quantitative traits 5 | 5
Obesity-related traits 569 | 569
Schizophrenia 533 | 533
Breast cancer 492 | 492
Body mass index 379 | 379
Height 369 | 369
Coronary artery disease 367 | 367
Blood protein levels 351 | 351
Post bronchodilator FEV1-FVC r... 308 | 308
Mean corpuscular volume 283 | 283
Platelet count 275 | 275
Intelligence (multi-trait anal... 267 | 267
Mean platelet volume 253 | 253
IgG glycosylation 250 | 250
Mean corpuscular hemoglobin 238 | 238
Inflammatory bowel disease 235 | 235
Plateletcrit 227 | 227
Crohn's disease 215 | 215
Type 2 diabetes 210 | 210
Red blood cell count 191 | 191
Monocyte count 183 | 183
Red cell distribution width 182 | 182
Eosinophil counts 180 | 180
Neuroticism 180 | 180
Platelet distribution width 174 | 174
Monocyte percentage of white c... 173 | 173
Post bronchodilator FEV1 173 | 173
Sum eosinophil basophil counts 173 | 173
White blood cell count 172 | 172
3-hydroxy-1-methylpropylmercap... 166 | 166
Eosinophil percentage of granu... 163 | 163
Eosinophil percentage of white... 163 | 163
Reticulocyte fraction of red c... 163 | 163
Ulcerative colitis 163 | 163
Granulocyte percentage of myel... 162 | 162
Itch intensity from mosquito b... 162 | 162
Systemic lupus erythematosus 159 | 159
High light scatter reticulocyt... 158 | 158
Lymphocyte counts 158 | 158
Reticulocyte count 158 | 158
Blood metabolite levels 157 | 157
Neutrophil count 154 | 154
High light scatter reticulocyt... 153 | 153
Neutrophil percentage of granu... 153 | 153
3-hydroxypropylmercapturic aci... 150 | 150
Tonsillectomy 149 | 149
Diastolic blood pressure 144 | 144
Sum basophil neutrophil counts 140 | 140
Autism spectrum disorder or sc... 134 | 134
Myeloid white cell count 133 | 133
Granulocyte count 132 | 132
Sum neutrophil eosinophil coun... 129 | 129
Colorectal cancer 126 | 126
Alzheimer disease and age of o... 124 | 124
Multiple sclerosis 124 | 124
Cholesterol, total 123 | 123
Night sleep phenotypes 123 | 123
Lung cancer 122 | 122
Lymphocyte percentage of white... 122 | 122
Menarche (age at onset) 122 | 122
Neutrophil percentage of white... 121 | 121
Rheumatoid arthritis 121 | 121
Systolic blood pressure 120 | 120
Immature fraction of reticuloc... 118 | 118
Diisocyanate-induced asthma 116 | 116
HDL cholesterol 116 | 116
Allergic disease (asthma, hay ... 115 | 115
Educational attainment (years ... 114 | 114
Hematocrit 113 | 113
Hemoglobin concentration 112 | 112
LDL cholesterol 110 | 110
QT interval 110 | 110
Waist circumference adjusted f... 110 | 110
Mosquito bite size 107 | 107
Asthma 106 | 106
Lobe attachment (rater-scored ... 103 | 103
Peripheral arterial disease (t... 101 | 101
Pulse pressure 97 | 97
Bipolar disorder 94 | 94
Major depressive disorder 94 | 94
Prostate cancer 92 | 92
Parkinson's disease 90 | 90
Hip circumference adjusted for... 89 | 89
Metabolite levels 87 | 87
Triglycerides 87 | 87
Colonoscopy-negative controls ... 85 | 85
Mean corpuscular hemoglobin co... 85 | 85
Itch intensity from mosquito b... 84 | 84
Bipolar disorder and schizophr... 83 | 83
Resting heart rate 82 | 82
Macrophage inflammatory protei... 81 | 81
Migraine 81 | 81
Waist-to-hip ratio adjusted fo... 81 | 81
PR interval in Tripanosoma cru... 80 | 80
Cognitive performance 79 | 79
Glomerular filtration rate (cr... 78 | 78
Late-onset Alzheimer's disease 78 | 78
Waist circumference adjusted f... 75 | 75
Tuberculosis 73 | 73
Type 1 diabetes 73 | 73
Morning vs. evening chronotype 72 | 72

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Probable E3 ubiquitin-protein ligase HECTD4 HECTD4 Tbio Enzyme -1.02570 11.0 0
Hematopoietic progenitor cell antigen CD34 CD34 Tbio Non-IDG -4.14691 13698.4 1952
Protein FAM3C FAM3C Tbio Non-IDG -1.76501 60.8 157
Plasma membrane calcium-transporting ATPase 1 ATP2B1 Tbio Transporter -2.01694 100.0 110
Alpha-ketoglutarate-dependent dioxygenase FTO FTO Tbio Enzyme -3.13021 1342.0 318