Development Level

Tbio 5 | 11,445
Tdark 1 | 6,588

IMPC Phenotype

decreased vertical activity 2 | 208
enlarged heart 2 | 210
abnormal heart morphology 1 | 162
abnormal seminal vesicle morph... 1 | 114
embryonic lethality prior to o... 1 | 239
embryonic lethality prior to t... 1 | 278
hypoactivity 1 | 132
preweaning lethality, complete... 1 | 979
preweaning lethality, incomple... 1 | 499

Disease

Carcinoma 5 | 11,493
lung carcinoma 4 | 2,843
ovarian cancer 4 | 8,520
Kidney cancer 3 | 2,613
atypical teratoid / rhabdoid tumor 3 | 5,112
ependymoma 3 | 4,679
glioblastoma 3 | 5,792
interstitial cystitis 3 | 2,312
intraductal papillary-mucinous neoplasm (IPMN) 3 | 3,291
lung cancer 3 | 4,740
medulloblastoma, large-cell 3 | 6,241
oligodendroglioma 3 | 2,850
psoriasis 3 | 6,694
Alzheimer's disease 2 | 658
Astrocytoma, Pilocytic 2 | 3,081
Autosomal recessive hypohidrotic ectodermal dysplasia syndrome 2 | 3
Ectodermal Dysplasia 10A, Hypohidrotic/Hair/Nail Type, Autosomal Dominant 2 | 3
Endometrial cancer 2 | 311
Hypohidrotic ectodermal dysplasia 2 | 15
acute quadriplegic myopathy 2 | 1,158
adult high grade glioma 2 | 3,801
astrocytic glioma 2 | 2,597
breast carcinoma 2 | 1,638
hereditary spastic paraplegia 2 | 318
intraductal papillary-mucinous adenoma (IPMA) 2 | 2,955
intraductal papillary-mucinous carcinoma (IPMC) 2 | 2,989
malignant mesothelioma 2 | 3,232
non-small cell lung cancer 2 | 2,890
tuberculosis 2 | 2,010
Abnormality of the fingernails 1 | 51
Acute necrotizing encephalitis 1 | 2
Adenoid Cystic Carcinoma 1 | 99
Alcohol dependence 1 | 107
Alopecia 1 | 115
Anhidrosis 1 | 23
Anodontia 1 | 12
Apraxia 1 | 26
Apraxias 1 | 27
Atopic dermatitis 1 | 952
Autistic Disorder 1 | 364
Autosomal dominant hypohidrotic ectodermal dysplasia syndrome (disorder) 1 | 3
Autosomal recessive hypohidrotic ectodermal dysplasia 1 | 3
Brain disease 1 | 96
Carcinoma, Adenoid Cystic 1 | 99
Clouston syndrome 1 | 9
Concave bridge of nose 1 | 195
Craniofacial Abnormalities 1 | 151
DOID:2627 1 | 94
Decreased size of teeth 1 | 62
Decreased width of tooth 1 | 59
Dental abnormalities 1 | 60
Depressed nasal bridge 1 | 195
Depressed nasal root/bridge 1 | 195
Dry skin 1 | 75
Dyslexia 1 | 43
Ectodermal Dysplasia 1 | 14
Ectodermal Dysplasia 3, Anhidrotic 1 | 2
Ectodermal Dysplasia, Hypohidrotic, Autosomal Recessive 1 | 3
Everted lower lip vermilion 1 | 54
Fibroma 1 | 18
Fine hair 1 | 42
Frontal bossing 1 | 157
Fuhrmann syndrome 1 | 7
Hypodontia 1 | 81
Hypohidrosis 1 | 34
Hypotrichosis 1 | 47
Inflammatory myofibroblastic tumor 1 | 8
Influenza 1 | 142
Keratoconus 1 | 113
Language Development Disorders 1 | 11
Large intestine cancer 1 | 126
Liver cancer 1 | 604
Major Depressive Disorder 1 | 301
Melanoma 1 | 711
Microdontia (disorder) 1 | 59
Nail dysplasia 1 | 52
Precocious exfoliation of primary tooth 1 | 11
Protruding lower lip 1 | 54
Silver-Russell syndrome 1 | 39
Skin cancer 1 | 469
Sparse eyebrow 1 | 42
Sparse eyelashes 1 | 31
Specific language impairment 1 | 34
Stuttering 1 | 17
Thick vermilion border 1 | 25
Tooth Abnormalities 1 | 69
Tooth agenesis 1 | 44
Unipolar Depression 1 | 250
Waldenstrons macroglobulinemia 1 | 765
Xerosis 1 | 75
active ulcerative colitis 1 | 764
astrocytoma 1 | 1,146
autosomal dominant Emery-Dreifuss muscular dystrophy 1 | 510
chronic rhinosinusitis 1 | 512
colon cancer 1 | 1,478
cystic fibrosis and chronic rhinosinusitis 1 | 214
fibroadenoma 1 | 559
nasopharyngeal carcinoma 1 | 1,058
progressive supranuclear palsy 1 | 676
urothelial carcinoma 1 | 318

Tissue

Blood and immune system 6 | 16,909
Cardiovascular System 6 | 15,192
Digestive Tract 6 | 17,369
Endocrine System 6 | 18,159
Female tissues 6 | 17,400
Liver and Pancreas 6 | 16,750
Male tissues 6 | 17,142
Respiratory system 6 | 16,393
Skin and soft tissues 6 | 17,230
Urinary Tract 6 | 16,678
Nervous System 5 | 16,725

Target Family

Non-IDG 3 | 12,091
Enzyme 2 | 4,145
Transcription Factor 1 | 1,400

GWAS Trait

Beard thickness 6 | 6
Obesity-related traits 569 | 569
Schizophrenia 533 | 533
Breast cancer 492 | 492
Body mass index 379 | 379
Height 369 | 369
Coronary artery disease 367 | 367
Blood protein levels 351 | 351
Post bronchodilator FEV1-FVC r... 308 | 308
Mean corpuscular volume 283 | 283
Platelet count 275 | 275
Intelligence (multi-trait anal... 267 | 267
Mean platelet volume 253 | 253
IgG glycosylation 250 | 250
Mean corpuscular hemoglobin 238 | 238
Inflammatory bowel disease 235 | 235
Plateletcrit 227 | 227
Crohn's disease 215 | 215
Type 2 diabetes 210 | 210
Red blood cell count 191 | 191
Monocyte count 183 | 183
Red cell distribution width 182 | 182
Eosinophil counts 180 | 180
Neuroticism 180 | 180
Platelet distribution width 174 | 174
Monocyte percentage of white c... 173 | 173
Post bronchodilator FEV1 173 | 173
Sum eosinophil basophil counts 173 | 173
White blood cell count 172 | 172
3-hydroxy-1-methylpropylmercap... 166 | 166
Eosinophil percentage of granu... 163 | 163
Eosinophil percentage of white... 163 | 163
Reticulocyte fraction of red c... 163 | 163
Ulcerative colitis 163 | 163
Granulocyte percentage of myel... 162 | 162
Itch intensity from mosquito b... 162 | 162
Systemic lupus erythematosus 159 | 159
High light scatter reticulocyt... 158 | 158
Lymphocyte counts 158 | 158
Reticulocyte count 158 | 158
Blood metabolite levels 157 | 157
Neutrophil count 154 | 154
High light scatter reticulocyt... 153 | 153
Neutrophil percentage of granu... 153 | 153
3-hydroxypropylmercapturic aci... 150 | 150
Tonsillectomy 149 | 149
Diastolic blood pressure 144 | 144
Sum basophil neutrophil counts 140 | 140
Autism spectrum disorder or sc... 134 | 134
Myeloid white cell count 133 | 133
Granulocyte count 132 | 132
Sum neutrophil eosinophil coun... 129 | 129
Colorectal cancer 126 | 126
Alzheimer disease and age of o... 124 | 124
Multiple sclerosis 124 | 124
Cholesterol, total 123 | 123
Night sleep phenotypes 123 | 123
Lung cancer 122 | 122
Lymphocyte percentage of white... 122 | 122
Menarche (age at onset) 122 | 122
Neutrophil percentage of white... 121 | 121
Rheumatoid arthritis 121 | 121
Systolic blood pressure 120 | 120
Immature fraction of reticuloc... 118 | 118
Diisocyanate-induced asthma 116 | 116
HDL cholesterol 116 | 116
Allergic disease (asthma, hay ... 115 | 115
Educational attainment (years ... 114 | 114
Hematocrit 113 | 113
Hemoglobin concentration 112 | 112
LDL cholesterol 110 | 110
QT interval 110 | 110
Waist circumference adjusted f... 110 | 110
Mosquito bite size 107 | 107
Asthma 106 | 106
Lobe attachment (rater-scored ... 103 | 103
Peripheral arterial disease (t... 101 | 101
Pulse pressure 97 | 97
Bipolar disorder 94 | 94
Major depressive disorder 94 | 94
Prostate cancer 92 | 92
Parkinson's disease 90 | 90
Hip circumference adjusted for... 89 | 89
Metabolite levels 87 | 87
Triglycerides 87 | 87
Colonoscopy-negative controls ... 85 | 85
Mean corpuscular hemoglobin co... 85 | 85
Itch intensity from mosquito b... 84 | 84
Bipolar disorder and schizophr... 83 | 83
Resting heart rate 82 | 82
Macrophage inflammatory protei... 81 | 81
Migraine 81 | 81
Waist-to-hip ratio adjusted fo... 81 | 81
PR interval in Tripanosoma cru... 80 | 80
Cognitive performance 79 | 79
Glomerular filtration rate (cr... 78 | 78
Late-onset Alzheimer's disease 78 | 78
Waist circumference adjusted f... 75 | 75
Tuberculosis 73 | 73
Type 1 diabetes 73 | 73
Morning vs. evening chronotype 72 | 72

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Microtubule-actin cross-linking factor 1, isoforms 1/2/3/5 MACF1 Tbio Non-IDG -2.05246 115.8 45
Uncharacterized protein C1orf127 C1orf127 Tdark Non-IDG 0.00000 0
Tumor necrosis factor receptor superfamily member EDAR EDAR Tbio Non-IDG -2.21203 161.3 194
E3 SUMO-protein ligase RanBP2 RANBP2 Tbio Enzyme -2.24609 178.6 172
Forkhead box protein P2 FOXP2 Tbio Transcription Factor -2.52644 311.4 340
E3 ubiquitin-protein ligase LNX LNX1 Tbio Enzyme -1.97887 97.9 146