Development Level

Tbio 29 | 11,445
Tdark 9 | 6,588
Tchem 8 | 1,598
Tclin 6 | 613

IMPC Phenotype

preweaning lethality, incomple... 4 | 499
abnormal bone structure 2 | 187
abnormal embryo size 2 | 220
abnormal seminal vesicle morph... 2 | 114
anophthalmia 2 | 33
decreased vertical activity 2 | 208
enlarged heart 2 | 210
hyperactivity 2 | 148
impaired glucose tolerance 2 | 75
microphthalmia 2 | 26
preweaning lethality, complete... 2 | 979
abnormal behavior 1 | 298
abnormal craniofacial morpholo... 1 | 33
abnormal facial morphology 1 | 17
abnormal head shape 1 | 10
abnormal heart morphology 1 | 162
abnormal outer ear morphology 1 | 3
decreased body length 1 | 101
decreased body weight 1 | 161
decreased bone mineral content 1 | 151
decreased bone mineral density 1 | 126
decreased caudal vertebrae num... 1 | 53
decreased circulating HDL chol... 1 | 68
decreased circulating alanine ... 1 | 47
decreased circulating aspartat... 1 | 34
decreased circulating choleste... 1 | 93
decreased circulating fructosa... 1 | 30
decreased circulating serum al... 1 | 82
decreased circulating total pr... 1 | 49
decreased lean body mass 1 | 135
decreased lumbar vertebrae num... 1 | 2
decreased neutrophil cell numb... 1 | 42
decreased startle reflex 1 | 75
embryonic lethality prior to t... 1 | 278
enlarged spleen 1 | 41
hypoactivity 1 | 132
increased lean body mass 1 | 172
increased lymphocyte cell numb... 1 | 32
increased respiratory quotient 1 | 2
increased spleen weight 1 | 10
mydriasis 1 | 6
prenatal lethality 1 | 28
prenatal lethality prior to he... 1 | 87
short tibia 1 | 97
vertebral transformation 1 | 12

Disease

Carcinoma 35 | 11,493
osteosarcoma 33 | 7,950
ovarian cancer 27 | 8,520
glioblastoma 20 | 5,792
medulloblastoma, large-cell 20 | 6,241
psoriasis 20 | 6,694
Cancer 17 | 2,499
atypical teratoid / rhabdoid tumor 17 | 5,112
ependymoma 16 | 4,679
adult high grade glioma 15 | 3,801
lung cancer 15 | 4,740
malignant mesothelioma 15 | 3,232
group 3 medulloblastoma 14 | 4,104
interstitial cystitis 13 | 2,312
Astrocytoma, Pilocytic 12 | 3,081
Breast cancer 12 | 3,578
Rheumatoid arthritis 12 | 1,191
lung adenocarcinoma 12 | 2,716
pancreatic cancer 12 | 2,398
ductal carcinoma in situ 11 | 1,745
intraductal papillary-mucinous carcinoma (IPMC) 11 | 2,989
intraductal papillary-mucinous neoplasm (IPMN) 11 | 3,291
ulcerative colitis 11 | 1,819
intraductal papillary-mucinous adenoma (IPMA) 10 | 2,955
lung carcinoma 10 | 2,843
pituitary cancer 10 | 1,972
Kidney cancer 9 | 2,613
breast carcinoma 9 | 1,638
diabetes mellitus 9 | 1,728
invasive ductal carcinoma 9 | 2,951
non-small cell lung cancer 9 | 2,890
Fever 8 | 138
cystic fibrosis 8 | 1,696
spina bifida 8 | 1,074
oligodendroglioma 7 | 2,850
primitive neuroectodermal tumor 7 | 3,035
subependymal giant cell astrocytoma 7 | 2,287
Autistic Disorder 6 | 364
Autosomal recessive predisposition 6 | 1,442
Multiple Sclerosis 6 | 540
esophageal adenocarcinoma 6 | 737
gastric carcinoma 6 | 807
Asthma 5 | 385
Bipolar Disorder 5 | 666
Carcinoma, Hepatocellular 5 | 228
Liver carcinoma 5 | 240
Multiple myeloma 5 | 1,332
Pick disease 5 | 1,894
Pulmonary Fibrosis 5 | 106
active ulcerative colitis 5 | 764
adrenocortical carcinoma 5 | 1,428
astrocytic glioma 5 | 2,597
astrocytoma 5 | 1,146
group 4 medulloblastoma 5 | 1,855
pancreatic ductal adenocarcinoma liver metastasis 5 | 1,962
primary Sjogren syndrome 5 | 735
Arthritis, Rheumatoid 4 | 174
Fatigue 4 | 182
Hypertension 4 | 396
Immune system cancer 4 | 140
Intellectual disability 4 | 1,016
Leukemia 4 | 104
Liver cancer 4 | 604
Lymphoid leukemia 4 | 160
Schizophrenia 4 | 1,160
Vasculitis 4 | 80
active Crohn's disease 4 | 922
acute myeloid leukemia 4 | 783
colon cancer 4 | 1,478
juvenile dermatomyositis 4 | 1,187
mucosa-associated lymphoid tissue lymphoma 4 | 484
primary pancreatic ductal adenocarcinoma 4 | 1,109
sarcoidosis 4 | 370
tuberculosis 4 | 2,010
Alzheimer's disease 3 | 658
Anemia 3 | 365
Arthritis 3 | 290
Blepharoptosis 3 | 231
Depressive disorder 3 | 409
Endometriosis 3 | 540
Highly variable severity 3 | 157
Hypereosinophilic syndrome 3 | 71
Kidney disease 3 | 430
Lung disease 3 | 142
Neuropathy 3 | 261
Osteoarthritis 3 | 184
Prostatic Neoplasms 3 | 495
Reperfusion Injury 3 | 86
Skin cancer 3 | 469
Variable expressivity 3 | 157
Vascular disease 3 | 319
Waldenstrons macroglobulinemia 3 | 765
acute quadriplegic myopathy 3 | 1,158
aldosterone-producing adenoma 3 | 665
atypical teratoid/rhabdoid tumor 3 | 357
dermatomyositis 3 | 966
gastric cancer 3 | 459
head and neck cancer 3 | 271
hepatocellular carcinoma 3 | 547
nephrosclerosis 3 | 333

Tissue

Digestive Tract 47 | 17,369
Female tissues 47 | 17,400
Skin and soft tissues 47 | 17,230
Blood and immune system 46 | 16,909
Endocrine System 46 | 18,159
Nervous System 46 | 16,725
Liver and Pancreas 45 | 16,750
Urinary Tract 45 | 16,678
Respiratory system 44 | 16,393
Male tissues 43 | 17,142
Cardiovascular System 38 | 15,192

Target Family

Non-IDG 22 | 12,091
Transcription Factor 9 | 1,400
Enzyme 8 | 4,145
GPCR 4 | 408
Transporter 4 | 473
Epigenetic 2 | 242
Kinase 2 | 634
Ion Channel 1 | 344

GWAS Trait

Basophil percentage of granulo... 52 | 52
Obesity-related traits 569 | 569
Schizophrenia 533 | 533
Breast cancer 492 | 492
Body mass index 379 | 379
Height 369 | 369
Coronary artery disease 367 | 367
Blood protein levels 351 | 351
Post bronchodilator FEV1-FVC r... 308 | 308
Mean corpuscular volume 283 | 283
Platelet count 275 | 275
Intelligence (multi-trait anal... 267 | 267
Mean platelet volume 253 | 253
IgG glycosylation 250 | 250
Mean corpuscular hemoglobin 238 | 238
Inflammatory bowel disease 235 | 235
Plateletcrit 227 | 227
Crohn's disease 215 | 215
Type 2 diabetes 210 | 210
Red blood cell count 191 | 191
Monocyte count 183 | 183
Red cell distribution width 182 | 182
Eosinophil counts 180 | 180
Neuroticism 180 | 180
Platelet distribution width 174 | 174
Monocyte percentage of white c... 173 | 173
Post bronchodilator FEV1 173 | 173
Sum eosinophil basophil counts 173 | 173
White blood cell count 172 | 172
3-hydroxy-1-methylpropylmercap... 166 | 166
Eosinophil percentage of granu... 163 | 163
Eosinophil percentage of white... 163 | 163
Reticulocyte fraction of red c... 163 | 163
Ulcerative colitis 163 | 163
Granulocyte percentage of myel... 162 | 162
Itch intensity from mosquito b... 162 | 162
Systemic lupus erythematosus 159 | 159
High light scatter reticulocyt... 158 | 158
Lymphocyte counts 158 | 158
Reticulocyte count 158 | 158
Blood metabolite levels 157 | 157
Neutrophil count 154 | 154
High light scatter reticulocyt... 153 | 153
Neutrophil percentage of granu... 153 | 153
3-hydroxypropylmercapturic aci... 150 | 150
Tonsillectomy 149 | 149
Diastolic blood pressure 144 | 144
Sum basophil neutrophil counts 140 | 140
Autism spectrum disorder or sc... 134 | 134
Myeloid white cell count 133 | 133
Granulocyte count 132 | 132
Sum neutrophil eosinophil coun... 129 | 129
Colorectal cancer 126 | 126
Alzheimer disease and age of o... 124 | 124
Multiple sclerosis 124 | 124
Cholesterol, total 123 | 123
Night sleep phenotypes 123 | 123
Lung cancer 122 | 122
Lymphocyte percentage of white... 122 | 122
Menarche (age at onset) 122 | 122
Neutrophil percentage of white... 121 | 121
Rheumatoid arthritis 121 | 121
Systolic blood pressure 120 | 120
Immature fraction of reticuloc... 118 | 118
Diisocyanate-induced asthma 116 | 116
HDL cholesterol 116 | 116
Allergic disease (asthma, hay ... 115 | 115
Educational attainment (years ... 114 | 114
Hematocrit 113 | 113
Hemoglobin concentration 112 | 112
LDL cholesterol 110 | 110
QT interval 110 | 110
Waist circumference adjusted f... 110 | 110
Mosquito bite size 107 | 107
Asthma 106 | 106
Lobe attachment (rater-scored ... 103 | 103
Peripheral arterial disease (t... 101 | 101
Pulse pressure 97 | 97
Bipolar disorder 94 | 94
Major depressive disorder 94 | 94
Prostate cancer 92 | 92
Parkinson's disease 90 | 90
Hip circumference adjusted for... 89 | 89
Metabolite levels 87 | 87
Triglycerides 87 | 87
Colonoscopy-negative controls ... 85 | 85
Mean corpuscular hemoglobin co... 85 | 85
Itch intensity from mosquito b... 84 | 84
Bipolar disorder and schizophr... 83 | 83
Resting heart rate 82 | 82
Macrophage inflammatory protei... 81 | 81
Migraine 81 | 81
Waist-to-hip ratio adjusted fo... 81 | 81
PR interval in Tripanosoma cru... 80 | 80
Cognitive performance 79 | 79
Glomerular filtration rate (cr... 78 | 78
Late-onset Alzheimer's disease 78 | 78
Waist circumference adjusted f... 75 | 75
Tuberculosis 73 | 73
Type 1 diabetes 73 | 73
Morning vs. evening chronotype 72 | 72

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Glutamate receptor-interacting protein 1 GRIP1 Tbio Non-IDG -2.18570 152.7 157
Activin receptor type-2A ACVR2A Tchem Kinase -2.08745 108.0 315
Palmitoyltransferase ZDHHC18 ZDHHC18 Tdark Enzyme 0.38 0.25 61
P2Y purinoceptor 2 P2RY2 Tclin GPCR -2.74629 565.7 192
AF4/FMR2 family member 1 AFF1 Tbio Transcription Factor -2.60388 403.1 201
Contactin-4 CNTN4 Tbio Non-IDG -1.54832 35.6 117
Putative uncharacterized protein encoded by LINC00299 LINC00299 Tdark Non-IDG 0.00000 0
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1 RPN1 Tbio Enzyme -2.17901 146.5 319
Protein GR6 LINC01565 Tdark Non-IDG 0.00000 0
Alpha-(1,3)-fucosyltransferase 6 FUT6 Tchem Enzyme -1.80643 59.7 183