Development Level

Tbio 22 | 11,445
Tchem 5 | 1,598
Tdark 4 | 6,588
Tclin 2 | 613

Collection

Ion Channel: IDG Consortium (T... 1 | 99

IMPC Phenotype

preweaning lethality, complete... 3 | 979
abnormal behavior 2 | 298
abnormal behavioral response t... 1 | 66
abnormal bone structure 1 | 187
abnormal optic disc morphology 1 | 10
abnormal tooth morphology 1 | 24
corneal opacity 1 | 32
decreased fasted circulating g... 1 | 65
decreased lactate dehydrogenas... 1 | 16
decreased lean body mass 1 | 135
decreased total body fat amoun... 1 | 207
enlarged heart 1 | 210
hyperactivity 1 | 148
impaired glucose tolerance 1 | 75
improved glucose tolerance 1 | 79
increased body length 1 | 32
increased bone mineral content 1 | 108
increased circulating alkaline... 1 | 122
increased lean body mass 1 | 172
increased total body fat amoun... 1 | 134
increased vertical activity 1 | 24
irregularly shaped pupil 1 | 7
prenatal lethality 1 | 28
small testis 1 | 58

Disease

Carcinoma 27 | 11,493
medulloblastoma, large-cell 21 | 6,241
ovarian cancer 21 | 8,520
Atrial Fibrillation 17 | 124
atypical teratoid / rhabdoid tumor 17 | 5,112
glioblastoma 16 | 5,792
psoriasis 16 | 6,694
lung cancer 15 | 4,740
osteosarcoma 15 | 7,950
ependymoma 14 | 4,679
Breast cancer 13 | 3,578
lung carcinoma 13 | 2,843
Astrocytoma, Pilocytic 12 | 3,081
Heart conduction disease 12 | 83
adult high grade glioma 12 | 3,801
malignant mesothelioma 11 | 3,232
non-small cell lung cancer 11 | 2,890
Kidney cancer 10 | 2,613
astrocytic glioma 10 | 2,597
oligodendroglioma 9 | 2,850
pituitary cancer 9 | 1,972
primitive neuroectodermal tumor 9 | 3,035
subependymal giant cell astrocytoma 9 | 2,287
group 3 medulloblastoma 8 | 4,104
interstitial cystitis 8 | 2,312
intraductal papillary-mucinous adenoma (IPMA) 8 | 2,955
intraductal papillary-mucinous carcinoma (IPMC) 8 | 2,989
pancreatic cancer 8 | 2,398
intraductal papillary-mucinous neoplasm (IPMN) 7 | 3,291
Autosomal recessive predisposition 6 | 1,442
Cancer 6 | 2,499
Pick disease 6 | 1,894
Schizophrenia 6 | 1,160
acute quadriplegic myopathy 6 | 1,158
lung adenocarcinoma 6 | 2,716
ulcerative colitis 6 | 1,819
Bipolar Disorder 5 | 666
Prostatic Neoplasms 5 | 495
colon cancer 5 | 1,478
cystic fibrosis 5 | 1,696
diabetes mellitus 5 | 1,728
invasive ductal carcinoma 5 | 2,951
juvenile dermatomyositis 5 | 1,187
spina bifida 5 | 1,074
Chronic Lymphocytic Leukemia 4 | 262
Congenital heart disease 4 | 93
Hypertension 4 | 396
Melanoma 4 | 711
Skin cancer 4 | 469
active ulcerative colitis 4 | 764
adrenocortical carcinoma 4 | 1,428
autosomal dominant Emery-Dreifuss muscular dystrophy 4 | 510
group 4 medulloblastoma 4 | 1,855
nasopharyngeal carcinoma 4 | 1,058
primary pancreatic ductal adenocarcinoma 4 | 1,109
Arthritis 3 | 290
Cerebrovascular disease 3 | 238
Cleft Palate 3 | 271
Congenital Heart Defects 3 | 58
Down syndrome 3 | 499
Duchenne muscular dystrophy 3 | 601
Heart Defects, Congenital 3 | 37
Heart disease 3 | 306
Highly variable severity 3 | 157
Liver Cirrhosis, Experimental 3 | 769
Liver cancer 3 | 604
Muscle Weakness 3 | 170
Neoplasm Metastasis 3 | 168
Obesity 3 | 678
Paroxysmal atrial fibrillation 3 | 14
Prostate cancer 3 | 175
Stomach Neoplasms 3 | 300
Variable expressivity 3 | 157
Vascular disease 3 | 319
aldosterone-producing adenoma 3 | 665
astrocytoma 3 | 1,146
dermatomyositis 3 | 966
mucosa-associated lymphoid tissue lymphoma 3 | 484
pancreatic carcinoma 3 | 562
pancreatic ductal adenocarcinoma liver metastasis 3 | 1,962
tuberculosis and treatment for 3 months 3 | 179
urothelial carcinoma 3 | 318
Alzheimer's disease 2 | 658
Arthritis, Juvenile 2 | 126
Atherosclerosis 2 | 291
Coronary artery disease 2 | 268
Creatine phosphokinase serum increased 2 | 110
Elevated creatine kinase 2 | 110
Endometrial cancer 2 | 311
Epilepsy 2 | 792
Essential Hypertension 2 | 94
Hepatomegaly 2 | 285
Mood Disorders 2 | 184
Multiple Sclerosis 2 | 540
active Crohn's disease 2 | 922
breast carcinoma 2 | 1,638
pediatric high grade glioma 2 | 1,064
posterior fossa group B ependymoma 2 | 416
progressive supranuclear palsy 2 | 676
tuberculosis 2 | 2,010

Tissue

Endocrine System 33 | 18,159
Digestive Tract 32 | 17,369
Female tissues 32 | 17,400
Male tissues 32 | 17,142
Nervous System 31 | 16,725
Blood and immune system 30 | 16,909
Cardiovascular System 30 | 15,192
Liver and Pancreas 30 | 16,750
Respiratory system 30 | 16,393
Urinary Tract 30 | 16,678
Skin and soft tissues 29 | 17,230

Target Family

Non-IDG 14 | 12,091
Ion Channel 6 | 344
Transcription Factor 6 | 1,400
Enzyme 4 | 4,145
Kinase 2 | 634
Transporter 1 | 473

GWAS Trait

Atrial fibrillation 33 | 33
Obesity-related traits 569 | 569
Schizophrenia 533 | 533
Breast cancer 492 | 492
Body mass index 379 | 379
Height 369 | 369
Coronary artery disease 367 | 367
Blood protein levels 351 | 351
Post bronchodilator FEV1-FVC r... 308 | 308
Mean corpuscular volume 283 | 283
Platelet count 275 | 275
Intelligence (multi-trait anal... 267 | 267
Mean platelet volume 253 | 253
IgG glycosylation 250 | 250
Mean corpuscular hemoglobin 238 | 238
Inflammatory bowel disease 235 | 235
Plateletcrit 227 | 227
Crohn's disease 215 | 215
Type 2 diabetes 210 | 210
Red blood cell count 191 | 191
Monocyte count 183 | 183
Red cell distribution width 182 | 182
Eosinophil counts 180 | 180
Neuroticism 180 | 180
Platelet distribution width 174 | 174
Monocyte percentage of white c... 173 | 173
Post bronchodilator FEV1 173 | 173
Sum eosinophil basophil counts 173 | 173
White blood cell count 172 | 172
3-hydroxy-1-methylpropylmercap... 166 | 166
Eosinophil percentage of granu... 163 | 163
Eosinophil percentage of white... 163 | 163
Reticulocyte fraction of red c... 163 | 163
Ulcerative colitis 163 | 163
Granulocyte percentage of myel... 162 | 162
Itch intensity from mosquito b... 162 | 162
Systemic lupus erythematosus 159 | 159
High light scatter reticulocyt... 158 | 158
Lymphocyte counts 158 | 158
Reticulocyte count 158 | 158
Blood metabolite levels 157 | 157
Neutrophil count 154 | 154
High light scatter reticulocyt... 153 | 153
Neutrophil percentage of granu... 153 | 153
3-hydroxypropylmercapturic aci... 150 | 150
Tonsillectomy 149 | 149
Diastolic blood pressure 144 | 144
Sum basophil neutrophil counts 140 | 140
Autism spectrum disorder or sc... 134 | 134
Myeloid white cell count 133 | 133
Granulocyte count 132 | 132
Sum neutrophil eosinophil coun... 129 | 129
Colorectal cancer 126 | 126
Alzheimer disease and age of o... 124 | 124
Multiple sclerosis 124 | 124
Cholesterol, total 123 | 123
Night sleep phenotypes 123 | 123
Lung cancer 122 | 122
Lymphocyte percentage of white... 122 | 122
Menarche (age at onset) 122 | 122
Neutrophil percentage of white... 121 | 121
Rheumatoid arthritis 121 | 121
Systolic blood pressure 120 | 120
Immature fraction of reticuloc... 118 | 118
Diisocyanate-induced asthma 116 | 116
HDL cholesterol 116 | 116
Allergic disease (asthma, hay ... 115 | 115
Educational attainment (years ... 114 | 114
Hematocrit 113 | 113
Hemoglobin concentration 112 | 112
LDL cholesterol 110 | 110
QT interval 110 | 110
Waist circumference adjusted f... 110 | 110
Mosquito bite size 107 | 107
Asthma 106 | 106
Lobe attachment (rater-scored ... 103 | 103
Peripheral arterial disease (t... 101 | 101
Pulse pressure 97 | 97
Bipolar disorder 94 | 94
Major depressive disorder 94 | 94
Prostate cancer 92 | 92
Parkinson's disease 90 | 90
Hip circumference adjusted for... 89 | 89
Metabolite levels 87 | 87
Triglycerides 87 | 87
Colonoscopy-negative controls ... 85 | 85
Mean corpuscular hemoglobin co... 85 | 85
Itch intensity from mosquito b... 84 | 84
Bipolar disorder and schizophr... 83 | 83
Resting heart rate 82 | 82
Macrophage inflammatory protei... 81 | 81
Migraine 81 | 81
Waist-to-hip ratio adjusted fo... 81 | 81
PR interval in Tripanosoma cru... 80 | 80
Cognitive performance 79 | 79
Glomerular filtration rate (cr... 78 | 78
Late-onset Alzheimer's disease 78 | 78
Waist circumference adjusted f... 75 | 75
Tuberculosis 73 | 73
Type 1 diabetes 73 | 73
Morning vs. evening chronotype 72 | 72

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Paired mesoderm homeobox protein 1 PRRX1 Tbio Transcription Factor -1.58479 38.8 304
Nesprin-2 SYNE2 Tbio Non-IDG -2.62747 380.6 39
Potassium voltage-gated channel subfamily D member 3 KCND3 Tclin Ion Channel -2.34610 217.9 162
Leucine-rich repeat-containing protein 63 LRRC63 Tdark Non-IDG 1.04 0.03 0
Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4 HCN4 Tclin Ion Channel -2.48671 270.6 121
Methylenetetrahydrofolate reductase MTHFR Tbio Enzyme -3.68447 5032.2 275
E3 ubiquitin-protein ligase NEURL1 NEURL1 Tbio Enzyme -1.09204 13.1 165
SH3 and PX domain-containing protein 2A SH3PXD2A Tbio Non-IDG -1.47710 30.7 110
Titin TTN Tbio Kinase -3.24415 1743.0 123
FAS-associated factor 1 FAF1 Tbio Non-IDG -1.71858 56.5 209