Development Level

Tbio 31 | 11,445
Tchem 6 | 1,598
Tdark 6 | 6,588
Tclin 3 | 613

Collection

GPCR: IDG Consortium (Targets) 1 | 126
Ion Channel: IDG Consortium (T... 1 | 99

IMPC Phenotype

preweaning lethality, incomple... 4 | 499
preweaning lethality, complete... 2 | 979
abnormal coat- hair morphology 1 | 19
abnormal embryo size 1 | 220
abnormal heart morphology 1 | 162
decreased circulating bilirubi... 1 | 19
decreased circulating creatini... 1 | 39
decreased circulating triglyce... 1 | 79
decreased heart rate 1 | 18
decreased vertical activity 1 | 208
impaired pupillary reflex 1 | 26
limb grasping 1 | 41
mydriasis 1 | 6
prenatal lethality prior to he... 1 | 87
prolonged RR interval 1 | 8
vertebral transformation 1 | 12

Disease

Carcinoma 39 | 11,493
ovarian cancer 24 | 8,520
medulloblastoma, large-cell 21 | 6,241
Kidney cancer 20 | 2,613
psoriasis 20 | 6,694
atypical teratoid / rhabdoid tumor 19 | 5,112
ependymoma 19 | 4,679
osteosarcoma 19 | 7,950
glioblastoma 18 | 5,792
adult high grade glioma 17 | 3,801
intraductal papillary-mucinous adenoma (IPMA) 16 | 2,955
lung cancer 16 | 4,740
Astrocytoma, Pilocytic 15 | 3,081
lung adenocarcinoma 13 | 2,716
pituitary cancer 13 | 1,972
astrocytic glioma 12 | 2,597
malignant mesothelioma 12 | 3,232
pancreatic cancer 12 | 2,398
Breast cancer 11 | 3,578
group 3 medulloblastoma 11 | 4,104
intraductal papillary-mucinous carcinoma (IPMC) 11 | 2,989
lung carcinoma 11 | 2,843
Asthma 10 | 385
ulcerative colitis 10 | 1,819
Cancer 9 | 2,499
invasive ductal carcinoma 9 | 2,951
non-small cell lung cancer 9 | 2,890
oligodendroglioma 9 | 2,850
primitive neuroectodermal tumor 9 | 3,035
Pick disease 8 | 1,894
acute quadriplegic myopathy 8 | 1,158
intraductal papillary-mucinous neoplasm (IPMN) 8 | 3,291
juvenile dermatomyositis 8 | 1,187
Autosomal recessive predisposition 7 | 1,442
Liver cancer 7 | 604
Schizophrenia 7 | 1,160
cystic fibrosis 7 | 1,696
ductal carcinoma in situ 7 | 1,745
subependymal giant cell astrocytoma 7 | 2,287
Epilepsy 6 | 792
Seizures 6 | 596
breast carcinoma 6 | 1,638
diabetes mellitus 6 | 1,728
medulloblastoma 6 | 720
Melanoma 5 | 711
Rheumatoid arthritis 5 | 1,191
adrenocortical carcinoma 5 | 1,428
group 4 medulloblastoma 5 | 1,855
interstitial cystitis 5 | 2,312
pancreatic ductal adenocarcinoma liver metastasis 5 | 1,962
primary Sjogren syndrome 5 | 735
primary pancreatic ductal adenocarcinoma 5 | 1,109
tuberculosis 5 | 2,010
Allergic rhinitis 4 | 94
Bipolar Disorder 4 | 666
Common cold 4 | 67
Fetal Growth Retardation 4 | 189
Infant, Small for Gestational Age 4 | 176
Intrauterine retardation 4 | 176
Parkinson's disease 4 | 392
Skin cancer 4 | 469
Small head 4 | 374
adrenocortical adenoma 4 | 131
colon cancer 4 | 1,478
gastric carcinoma 4 | 807
nasopharyngeal carcinoma 4 | 1,058
non primary Sjogren syndrome sicca 4 | 891
pancreatic carcinoma 4 | 562
Adenoid Cystic Carcinoma 3 | 99
Allergic hypersensitivity disease 3 | 126
Arthritis 3 | 290
Atopic dermatitis 3 | 952
Attention deficit hyperactivity disorder 3 | 278
Autistic Disorder 3 | 364
Carcinoma, Adenoid Cystic 3 | 99
Cardiovascular system disease 3 | 246
Cognitive delay 3 | 608
Depressive disorder 3 | 409
Duchenne muscular dystrophy 3 | 601
Glaucoma 3 | 239
Global developmental delay 3 | 608
Hypereosinophilic syndrome 3 | 71
Intellectual disability 3 | 1,016
Lissencephaly 3 | 69
Low-set, posteriorly rotated ears 3 | 110
Lung diseases 3 | 50
Mental Depression 3 | 333
Mental and motor retardation 3 | 608
Multiple myeloma 3 | 1,332
Muscle hypotonia 3 | 571
Nystagmus 3 | 317
Pneumonia 3 | 174
Short stature 3 | 531
Thrombocytopenia 3 | 197
autosomal dominant Emery-Dreifuss muscular dystrophy 3 | 510
cutaneous lupus erythematosus 3 | 1,057
dermatomyositis 3 | 966
fibroadenoma 3 | 559
non-small cell lung carcinoma 3 | 317
spina bifida 3 | 1,074

Tissue

Endocrine System 44 | 18,159
Digestive Tract 43 | 17,369
Liver and Pancreas 43 | 16,750
Male tissues 43 | 17,142
Skin and soft tissues 43 | 17,230
Blood and immune system 42 | 16,909
Female tissues 42 | 17,400
Nervous System 42 | 16,725
Respiratory system 40 | 16,393
Urinary Tract 39 | 16,678
Cardiovascular System 31 | 15,192

Target Family

Non-IDG 29 | 12,091
Enzyme 4 | 4,145
GPCR 4 | 408
Kinase 3 | 634
Epigenetic 2 | 242
Ion Channel 2 | 344
Transcription Factor 1 | 1,400
Transporter 1 | 473

GWAS Trait

Asthma (childhood onset) 46 | 46
Obesity-related traits 569 | 569
Schizophrenia 533 | 533
Breast cancer 492 | 492
Body mass index 379 | 379
Height 369 | 369
Coronary artery disease 367 | 367
Blood protein levels 351 | 351
Post bronchodilator FEV1-FVC r... 308 | 308
Mean corpuscular volume 283 | 283
Platelet count 275 | 275
Intelligence (multi-trait anal... 267 | 267
Mean platelet volume 253 | 253
IgG glycosylation 250 | 250
Mean corpuscular hemoglobin 238 | 238
Inflammatory bowel disease 235 | 235
Plateletcrit 227 | 227
Crohn's disease 215 | 215
Type 2 diabetes 210 | 210
Red blood cell count 191 | 191
Monocyte count 183 | 183
Red cell distribution width 182 | 182
Eosinophil counts 180 | 180
Neuroticism 180 | 180
Platelet distribution width 174 | 174
Monocyte percentage of white c... 173 | 173
Post bronchodilator FEV1 173 | 173
Sum eosinophil basophil counts 173 | 173
White blood cell count 172 | 172
3-hydroxy-1-methylpropylmercap... 166 | 166
Eosinophil percentage of granu... 163 | 163
Eosinophil percentage of white... 163 | 163
Reticulocyte fraction of red c... 163 | 163
Ulcerative colitis 163 | 163
Granulocyte percentage of myel... 162 | 162
Itch intensity from mosquito b... 162 | 162
Systemic lupus erythematosus 159 | 159
High light scatter reticulocyt... 158 | 158
Lymphocyte counts 158 | 158
Reticulocyte count 158 | 158
Blood metabolite levels 157 | 157
Neutrophil count 154 | 154
High light scatter reticulocyt... 153 | 153
Neutrophil percentage of granu... 153 | 153
3-hydroxypropylmercapturic aci... 150 | 150
Tonsillectomy 149 | 149
Diastolic blood pressure 144 | 144
Sum basophil neutrophil counts 140 | 140
Autism spectrum disorder or sc... 134 | 134
Myeloid white cell count 133 | 133
Granulocyte count 132 | 132
Sum neutrophil eosinophil coun... 129 | 129
Colorectal cancer 126 | 126
Alzheimer disease and age of o... 124 | 124
Multiple sclerosis 124 | 124
Cholesterol, total 123 | 123
Night sleep phenotypes 123 | 123
Lung cancer 122 | 122
Lymphocyte percentage of white... 122 | 122
Menarche (age at onset) 122 | 122
Neutrophil percentage of white... 121 | 121
Rheumatoid arthritis 121 | 121
Systolic blood pressure 120 | 120
Immature fraction of reticuloc... 118 | 118
Diisocyanate-induced asthma 116 | 116
HDL cholesterol 116 | 116
Allergic disease (asthma, hay ... 115 | 115
Educational attainment (years ... 114 | 114
Hematocrit 113 | 113
Hemoglobin concentration 112 | 112
LDL cholesterol 110 | 110
QT interval 110 | 110
Waist circumference adjusted f... 110 | 110
Mosquito bite size 107 | 107
Asthma 106 | 106
Lobe attachment (rater-scored ... 103 | 103
Peripheral arterial disease (t... 101 | 101
Pulse pressure 97 | 97
Bipolar disorder 94 | 94
Major depressive disorder 94 | 94
Prostate cancer 92 | 92
Parkinson's disease 90 | 90
Hip circumference adjusted for... 89 | 89
Metabolite levels 87 | 87
Triglycerides 87 | 87
Colonoscopy-negative controls ... 85 | 85
Mean corpuscular hemoglobin co... 85 | 85
Itch intensity from mosquito b... 84 | 84
Bipolar disorder and schizophr... 83 | 83
Resting heart rate 82 | 82
Macrophage inflammatory protei... 81 | 81
Migraine 81 | 81
Waist-to-hip ratio adjusted fo... 81 | 81
PR interval in Tripanosoma cru... 80 | 80
Cognitive performance 79 | 79
Glomerular filtration rate (cr... 78 | 78
Late-onset Alzheimer's disease 78 | 78
Waist circumference adjusted f... 75 | 75
Tuberculosis 73 | 73
Type 1 diabetes 73 | 73
Morning vs. evening chronotype 72 | 72

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Tyrosine-protein kinase Fer FER Tchem Kinase -1.86307 55.4 414
Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 1 MAGI1 Tbio Enzyme -1.08587 12.0 153
Kelch-like protein 5 KLHL5 Tdark Non-IDG 0.04 0.81 49
Pleckstrin homology domain-containing family G member 4B PLEKHG4B Tdark Non-IDG 0.00000 1.25 20
Gasdermin-A GSDMA Tbio Non-IDG -1.44401 26.7 77
5,6-dihydroxyindole-2-carboxylic acid oxidase TYRP1 Tbio Enzyme -2.95336 876.7 309
Metabotropic glutamate receptor 4 GRM4 Tchem GPCR -2.34335 217.2 150
Serine/threonine-protein kinase DCLK1 DCLK1 Tchem Kinase -2.08177 129.5 320
Cadherin-related family member 3 CDHR3 Tdark Non-IDG -1.12856 13.9 46
Low-density lipoprotein receptor-related protein 1B LRP1B Tbio Non-IDG -1.54531 39.3 15