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Target Filters...

Development Level

Tbio 12 | 11,445
Tclin 2 | 613
Tchem 1 | 1,598

IMPC Phenotype

abnormal gait 1 | 69
abnormal sleep behavior 1 | 70
convulsive seizures 1 | 13
decreased total body fat amoun... 1 | 207
increased body length 1 | 32
increased fasted circulating g... 1 | 76
preweaning lethality, complete... 1 | 979
preweaning lethality, incomple... 1 | 499

Disease

osteosarcoma 9 | 7,950
ovarian cancer 9 | 8,520
Carcinoma 8 | 11,493
Cardiovascular system disease 7 | 246
psoriasis 6 | 6,694
ependymoma 5 | 4,679
medulloblastoma, large-cell 5 | 6,241
ulcerative colitis 5 | 1,819
Breast cancer 4 | 3,578
glioblastoma 4 | 5,792
interstitial cystitis 4 | 2,312
intraductal papillary-mucinous adenoma (IPMA) 4 | 2,955
intraductal papillary-mucinous neoplasm (IPMN) 4 | 3,291
pancreatic cancer 4 | 2,398
Acquired metabolic disease 3 | 336
Cancer 3 | 2,499
adrenocortical carcinoma 3 | 1,428
atypical teratoid / rhabdoid tumor 3 | 5,112
group 3 medulloblastoma 3 | 4,104
interstitial lung disease 3 | 298
intraductal papillary-mucinous carcinoma (IPMC) 3 | 2,989
lung adenocarcinoma 3 | 2,716
lung cancer 3 | 4,740
non-small cell lung cancer 3 | 2,890
primitive neuroectodermal tumor 3 | 3,035
Adenoma 2 | 167
Astrocytoma, Pilocytic 2 | 3,081
Autistic Disorder 2 | 364
Chondroma 2 | 15
Chronic obstructive pulmonary disease 2 | 184
Epilepsy 2 | 792
Heart disease 2 | 306
Kidney cancer 2 | 2,613
Leiomyoma 2 | 32
Multiple Sclerosis 2 | 540
Schizophrenia 2 | 1,160
Tremor 2 | 113
Type 2 diabetes mellitus 2 | 272
adult high grade glioma 2 | 3,801
breast carcinoma 2 | 1,638
cutaneous lupus erythematosus 2 | 1,057
cystic fibrosis 2 | 1,696
cystic fibrosis and chronic rhinosinusitis 2 | 214
ductal carcinoma in situ 2 | 1,745
esophageal adenocarcinoma 2 | 737
group 4 medulloblastoma 2 | 1,855
head and neck cancer 2 | 271
invasive ductal carcinoma 2 | 2,951
malignant mesothelioma 2 | 3,232
oligodendroglioma 2 | 2,850
primary pancreatic ductal adenocarcinoma 2 | 1,109
Absence Epilepsy 1 | 22
Acute coronary syndrome 1 | 39
Acute stress disorder 1 | 6
Arrhythmias, Cardiac 1 | 19
Batten disease 1 | 13
Carcinoma, Non-Small-Cell Lung 1 | 107
Cardiac arrest 1 | 36
Cardioversion of Atrial Fibrillation 1 | 9
Celiac disease 1 | 116
Choledochal Cyst 1 | 9
Chromosome 1p36 deletion syndrome 1 | 23
Chronic fatigue syndrome 1 | 25
Common variable immunodeficiency 1 | 101
Conventional (Clear Cell) Renal Cell Carcinoma 1 | 6
Exfoliation Syndrome 1 | 12
Fatty liver disease 1 | 103
Gastrointestinal stromal tumor 1 | 62
Gilles de la Tourette syndrome 1 | 47
Hydranencephaly 1 | 11
Hyperpigmentation 1 | 37
Hypertensive disorder 1 | 56
Iris disease 1 | 10
Leiomyosarcoma 1 | 24
Limb Deformities, Congenital 1 | 16
Lipodystrophy 1 | 40
Mild Mental Retardation 1 | 70
Myocardial Infarction Prevention 1 | 7
Myoclonus 1 | 74
Neoplasms 1 | 63
Neurilemmoma 1 | 23
Neuronal ceroid lipofuscinosis 1 | 28
Neuronal ceroid lipofuscinosis 1 1 | 15
Neuronal ceroid lipofuscinosis 2 1 | 17
Nonorganic psychosis 1 | 84
Perinatal necrotizing enterocolitis 1 | 21
Primary Prevention of Coronary Heart Disease 1 | 4
Prinzmetal angina 1 | 6
Salivary Gland Adenoma, Pleomorphic 1 | 2
Salivary Gland Pleomorphic Adenoma 1 | 2
Scoliosis 1 | 44
Subarachnoid intracranial hemorrhage 1 | 3
Syncope 1 | 22
Synovial sarcoma 1 | 25
Timothy syndrome 1 | 11
Urologic Neoplasms 1 | 8
Uterine fibroid 1 | 28
Vesicoureteral reflux 1 | 32
Williams-Beuren syndrome 1 | 50
uncontrolled asthma 1 | 56

Tissue

Blood and immune system 14 | 16,909
Cardiovascular System 14 | 15,192
Digestive Tract 14 | 17,369
Endocrine System 14 | 18,159
Female tissues 14 | 17,400
Liver and Pancreas 14 | 16,750
Male tissues 14 | 17,142
Nervous System 14 | 16,725
Respiratory system 14 | 16,393
Skin and soft tissues 14 | 17,230
Urinary Tract 14 | 16,678

Target Family

Enzyme 6 | 4,145
Non-IDG 5 | 12,091
Ion Channel 2 | 344
TF/Epigenetic 1 | 38
Transcription Factor 1 | 1,400

GWAS Trait

Aortic root size 15 | 15
Obesity-related traits 569 | 569
Schizophrenia 533 | 533
Breast cancer 492 | 492
Body mass index 379 | 379
Height 369 | 369
Coronary artery disease 367 | 367
Blood protein levels 351 | 351
Post bronchodilator FEV1-FVC r... 308 | 308
Mean corpuscular volume 283 | 283
Platelet count 275 | 275
Intelligence (multi-trait anal... 267 | 267
Mean platelet volume 253 | 253
IgG glycosylation 250 | 250
Mean corpuscular hemoglobin 238 | 238
Inflammatory bowel disease 235 | 235
Plateletcrit 227 | 227
Crohn's disease 215 | 215
Type 2 diabetes 210 | 210
Red blood cell count 191 | 191
Monocyte count 183 | 183
Red cell distribution width 182 | 182
Eosinophil counts 180 | 180
Neuroticism 180 | 180
Platelet distribution width 174 | 174
Monocyte percentage of white c... 173 | 173
Post bronchodilator FEV1 173 | 173
Sum eosinophil basophil counts 173 | 173
White blood cell count 172 | 172
3-hydroxy-1-methylpropylmercap... 166 | 166
Eosinophil percentage of granu... 163 | 163
Eosinophil percentage of white... 163 | 163
Reticulocyte fraction of red c... 163 | 163
Ulcerative colitis 163 | 163
Granulocyte percentage of myel... 162 | 162
Itch intensity from mosquito b... 162 | 162
Systemic lupus erythematosus 159 | 159
High light scatter reticulocyt... 158 | 158
Lymphocyte counts 158 | 158
Reticulocyte count 158 | 158
Blood metabolite levels 157 | 157
Neutrophil count 154 | 154
High light scatter reticulocyt... 153 | 153
Neutrophil percentage of granu... 153 | 153
3-hydroxypropylmercapturic aci... 150 | 150
Tonsillectomy 149 | 149
Diastolic blood pressure 144 | 144
Sum basophil neutrophil counts 140 | 140
Autism spectrum disorder or sc... 134 | 134
Myeloid white cell count 133 | 133
Granulocyte count 132 | 132
Sum neutrophil eosinophil coun... 129 | 129
Colorectal cancer 126 | 126
Alzheimer disease and age of o... 124 | 124
Multiple sclerosis 124 | 124
Cholesterol, total 123 | 123
Night sleep phenotypes 123 | 123
Lung cancer 122 | 122
Lymphocyte percentage of white... 122 | 122
Menarche (age at onset) 122 | 122
Neutrophil percentage of white... 121 | 121
Rheumatoid arthritis 121 | 121
Systolic blood pressure 120 | 120
Immature fraction of reticuloc... 118 | 118
Diisocyanate-induced asthma 116 | 116
HDL cholesterol 116 | 116
Allergic disease (asthma, hay ... 115 | 115
Educational attainment (years ... 114 | 114
Hematocrit 113 | 113
Hemoglobin concentration 112 | 112
LDL cholesterol 110 | 110
QT interval 110 | 110
Waist circumference adjusted f... 110 | 110
Mosquito bite size 107 | 107
Asthma 106 | 106
Lobe attachment (rater-scored ... 103 | 103
Peripheral arterial disease (t... 101 | 101
Pulse pressure 97 | 97
Bipolar disorder 94 | 94
Major depressive disorder 94 | 94
Prostate cancer 92 | 92
Parkinson's disease 90 | 90
Hip circumference adjusted for... 89 | 89
Metabolite levels 87 | 87
Triglycerides 87 | 87
Colonoscopy-negative controls ... 85 | 85
Mean corpuscular hemoglobin co... 85 | 85
Itch intensity from mosquito b... 84 | 84
Bipolar disorder and schizophr... 83 | 83
Resting heart rate 82 | 82
Macrophage inflammatory protei... 81 | 81
Migraine 81 | 81
Waist-to-hip ratio adjusted fo... 81 | 81
PR interval in Tripanosoma cru... 80 | 80
Cognitive performance 79 | 79
Glomerular filtration rate (cr... 78 | 78
Late-onset Alzheimer's disease 78 | 78
Waist circumference adjusted f... 75 | 75
Tuberculosis 73 | 73
Type 1 diabetes 73 | 73
Morning vs. evening chronotype 72 | 72

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Telomerase-binding protein EST1A SMG6 Tbio Enzyme -1.48788 32.6 37
Leukemia-associated protein 1 DLEU1 Tbio Non-IDG -1.81742 64.9 26
Lysyl oxidase homolog 1 LOXL1 Tbio Enzyme -2.55611 364.6 174
Palmdelphin PALMD Tbio Non-IDG -0.87030 4.82 111
High mobility group protein HMGI-C HMGA2 Tbio Transcription Factor -3.26377 1794.1 235
Aspartate aminotransferase, mitochondrial GOT2 Tbio Enzyme -3.23630 1435.0 450
Anoctamin-1 ANO1 Tclin Ion Channel -2.58674 414.4 565
Putative histone-lysine N-methyltransferase PRDM6 PRDM6 Tbio TF/Epigenetic -0.89332 7.63 84
BTB/POZ domain-containing protein KCTD7 KCTD7 Tbio Non-IDG -1.52412 35.2 98
Craniofacial development protein 1 CFDP1 Tbio Non-IDG -1.74804 57.2 169